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遺伝子材料開発室より入手したDNAやウイルス株を用いて成果を論文発表される場合、必ず理研BRCならびに文部科学省ナショナルバイオリソースプロジェクトへの謝辞 (Acknowledgement) をAcknowledgement欄やMaterials & Methods欄に記載して頂くようお願い申し上げます。このことにより当該遺伝子材料に付加価値をつけることになり、さらに「ナショナルバイオリソースプロジェクト」や「理研BRC」の貢献を広く科学者に知らしめることができ、社会的にも貢献することになります。また、研究成果(論文)を刊行された場合は、その情報を当開発室までご送付いただければ幸甚です。
2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 and before
2019
Title | Author | Journal | NBRP RRC ID | PubMed PMID |
---|---|---|---|---|
Structural comparisons of phosphoenolpyruvate carboxykinases reveal the evolutionary trajectories of these phosphodiester energy-conversion enzymes. | Chiba, Y., Miyakawa, T., Shimane, Y., Takai, K., Tanokura, M., Nozaki, T. | J. Biol. Chem. pii: jbc.RA119.010920 (2019). | 57725 | 31662435 |
A pull-down and slot blot-based screening system for inhibitor compounds of the podoplanin-CLEC-2 interaction. | Watanabe, N., Kidokoro, M., Suzuki, Y., Tanaka, M., Inoue, S., Tsukamoto, H., Hirayama, N., Hsieh, P.W., Tseng, C.P., Nakagawa, Y., Inokuchi, S. | PLoS One 14 (9): e0222331 (2019). | 57724 | 31553741 |
Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate. | Arai, H.N., Sato, F., Yamamoto, T., Woltjen, K., Kiyonari, H., Yoshimoto, Y., Shukunami, C., Akiyama, H., Kist, R., Sehara-Fujisawa, A. | Cell Rep. 29 (3): 603-616.e5 (2019). | 57723 | 31618630 |
FRET-assisted photoactivation of flavoproteins for in vivo two-photon optogenetics. | Kinjo, T., Terai, K., Horita, S., Nomura, N., Sumiyama, K., Togashi, K., Iwata, S., Matsuda, M. | Nat. Methods. 16 (10): 1029-1036 (2019). | 57649 | 31501546 |
Characterization of doxycycline-dependent inducible Simian Virus 40 large T antigen immortalized human conjunctival epithelial cell line. | Mitani, A., Kobayashi, T., Hayashi, Y., Matsushita, N., Matsushita, S., Nakao, S., Takahira, N., Shiraishi, A., Ohashi, Y. | PLoS One 14 (9): e0222454 (2019). | 57648 | 31509592 |
KLF4 prevents epithelial to mesenchymal transition in human corneal epithelial cells via endogenous TGF-beta2 suppression. | Fujimoto, S., Hayashi, R., Hara, S., Sasamoto, Y., Harrington, J., Tsujikawa, M., Nishida, K. | Regen. Ther. 11: 249-257 (2019). | 57647 | 31538102 |
DCAF7 is required for maintaining the cellular levels of ERCC1-XPF and nucleotide excision repair. | Kawara, H., Akahori, R., Wakasugi, M., Sancar, A., Matsunaga, T. | Biochem. Biophys. Res. Commun. 519 (1): 204-210 (2019). | 57640 | 31493872 |
GREB1 induced by Wnt signaling promotes development of hepatoblastoma by suppressing TGFbeta signaling. | Matsumoto, S., Yamamichi, T., Shinzawa, K., Kasahara, Y., Nojima, S., Kodama, T., Obika, S., Takehara, T., Morii, E., Okuyama, H., Kikuchi, A. | Nat. Commun. 10(1): 3882 (2019). | 57639 | 31462641 |
Establishment of immortalized primary cell from the critically endangered Bonin flying fox (Pteropus pselaphon). | Tani, T., Eitsuka, T., Katayama, M., Nagamine, T., Nakaya, Y., Suzuki, H., Kiyono, T., Nakagawa, K., Inoue-Murayama, M., Onuma, M., Fukuda, T. | PLoS One 14 (8): e0221364 (2019). | 57638 | 31449544 |
he novel lncRNA CALIC upregulates AXL to promote colon cancer metastasis. | Kawasaki, Y., Miyamoto, M., Oda, T., Matsumura, K., Negishi, L., Nakato, R., Suda, S., Yokota, N., Shirahige, K., Akiyama, T. | EMBO Rep. 20 (8): e47052 (2019). | 57604 | 31353791 |
Soluble SLAMF7 promotes the growth of myeloma cells via homophilic interaction with surface SLAMF7. | Kikuchi, J., Hori, M., Iha, H., Toyama-Sorimachi, N., Hagiwara, S., Kuroda, Y., Koyama, D., Izumi, T., Yasui, H., Suzuki, A., Furukawa, Y. | Leukemia. 2019 Jul 29. . [Epub ahead of print] | 57603 | 31358854 |
Distinct Connectivity and Functionality of Aldehyde Dehydrogenase 1a1-Positive Nigrostriatal Dopaminergic Neurons in Motor Learning. | Wu, J., Kung, J., Dong, J., Chang, L., Xie, C., Habib, A., Hawes, S., Yang, N., Chen, V., Liu, Z., Evans, R., Liang, B., Sun, L., Ding, J., Yu, J., Saez-Atienzar, S., Tang, B., Khaliq, Z., Lin, D.T., Le, W., Cai, H. | Cell Rep. 28 (5): 1167-1181.e7 (2019). | 57558 | 31365862 |
Secretion of high amounts of hepatocyte growth factor is a characteristic feature of cancer-associated fibroblasts with EGFR-TKI resistance-promoting phenotype: A study of 18 cases of cancer-associated fibroblasts. | Suzuki, E., Yamazaki, S., Naito, T., Hashimoto, H., Okubo, S., Udagawa, H., Goto, K., Tsuboi, M., Ochiai, A., Ishii, G. | Pathol. Int. 69 (8): 472-480 (2019). | 57557 | 31339210 |
Protective effect of sestrin2 against iron overload and ferroptosis-induced liver injury. | Park, S.J., Cho, S.S., Kim, K.M., Yang, J.H., Kim, J.H., Jeong, E.H., Yang, J.W., Han, C.Y., Ku, S.K., Cho, I.J., Ki, S.H. | Toxicol. Appl. Pharmacol. 379: 114665 (2019). | 57549 | 31323261 |
GABARAPs dysfunction by autophagy deficiency in adolescent brain impairs GABAA receptor trafficking and social behavior. | Hui, K.K., Takashima, N., Watanabe, A., Chater, T.E., Matsukawa, H., Nekooki-Machida, Y., Nilsson, P., Endo, R., Goda, Y., Saido, T.C., Yoshikawa, T., Tanaka, M. | Sci. Adv. 5 (4): eaau8237 (2019). | 57548 | 30989111 |
Oral gram-positive bacterial DNA-based identification of saliva from highly degraded samples. | Ohta, J., Sakurada, K. | Forensic Sci. Int. Genet. 42: 103-112 (2019). | 57546 | 31302459 |
Pericentrin-mediated SAS-6 recruitment promotes centriole assembly. | Ito, D., Zitouni, S., Jana, S.C., Duarte, P., Surkont, J., Carvalho-Santos, Z., Pereira-Leal, J.B., Ferreira, M.G., Bettencourt-Dias, M. | Elife 8. pii: e41418 (2019). | 57531 | 31182187 |
CKAP4 Regulates Cell Migration via the Interaction with and Recycling of Integrin. | Osugi, Y., Fumoto, K., Kikuchi, A. | Mol. Cell. Biol. 39 (16). pii: e00073-19 (2019). | 57530 | 31160493 |
A Highly Versatile Expression System for the Production of Multiply Phosphorylated Proteins. | Zhu, P., Gafken, P.R., Mehl, R.A., Cooley, R.B. | ACS Chem. Biol. 14 (7): 1564-1572 (2019). | 57446 | 31243963 |
Quantitation of the neural silencing activity of anion channelrhodopsins in Caenorhabditis elegans and their applicability for long-term illumination. | Yamanashi, T., Maki, M., Kojima, K., Shibukawa, A., Tsukamoto, T., Chowdhury, S., Yamanaka, A., Takagi, S., Sudo, Y. | Sci. Rep. 9 (1): 7863 (2019). | 57439 | 31133660 |
Acute spatial spread of NO-mediated potentiation during hindpaw ischaemia in mice. | Onishi, T., Watanabe, T., Sasaki, M., Kamiya, Y., Horie, M., Tsukano, H., Hishida, R., Kohno, T., Takebayashi, H., Baba, H., Shibuki, K. | J. Physiol. 597 (13): 3441-3455 (2019). | 57438 | 31087329 |
Reduced Folate Carrier: an Entry Receptor for a Novel Feline Leukemia Virus Variant. | Miyake, A., Kawasaki, J., Ngo, H., Makundi, I., Muto, Y., Khan, A.H., Smith, D.J., Nishigaki, K. | J. Virol. 93 (13). pii: e00269-19 (2019). | 57424 | 30996094 |
Organoid culture containing cancer cells and stromal cells reveals that podoplanin-positive cancer-associated fibroblasts enhance proliferation of lung cancer cells. | Nakamura, H., Sugano, M., Miyashita, T., Hashimoto, H., Ochiai, A., Suzuki, K., Tsuboi, M., Ishii, G. | Lung Cancer 134: 100-107 (2019). | 57423 | 31319967 |
ROS amplification drives mouse spermatogonial stem cell self-renewal. | Morimoto, H., Kanastu-Shinohara, M., Ogonuki, N., Kamimura, S., Ogura, A., Yabe-Nishimura, C., Mori, Y., Morimoto, T., Watanabe, S., Otsu, K., Yamamoto, T., Shinohara, T. | Life Sci. Alliance 2 (2). pii: e201900374 (2019). | 57374 | 30940732 |
Thermostable CITase from Thermoanaerobacter thermocopriae shows negative cooperativity. | Yang, S.J., Choi, S.J., Park, B.R., Kim, Y.M. | Biotechnol. Lett. 41 (4-5): 625-632 (2019). | 57067 | 30927134 |
High filamin-C expression predicts enhanced invasiveness and poor outcome in glioblastoma multiforme. | Kamil, M., Shinsato, Y., Higa, N., Hirano, T., Idogawa, M., Takajo, T., Minami, K., Shimokawa, M., Yamamoto, M., Kawahara, K., Yonezawa, H., Hirano, H., Furukawa, T., Yoshimoto, K., Arita, K. | Br. J. Cancer. 120 (8): 819-826 (2019). | 56570 | 30867563 |
Wnt/beta-catenin signaling, which is activated in odontomas, reduces Sema3A expression to regulate odontogenic epithelial cell proliferation and tooth germ development. | Fujii, S., Nagata, K., Matsumoto, S., Kohashi, K.I., Kikuchi, A., Oda, Y., Kiyoshima, T., Wada, N. | Sci. Rep. 9 (1): 4257 (2019). | 55035 | 30862786 |
Role for tyrosine phosphorylation of SUV39H1 histone methyltransferase in enhanced trimethylation of histone H3K9 via neuregulin-1/ErbB4 nuclear signaling. | Nakajo, H., Ishibashi, K., Aoyama, K., Kubota, S., Hasegawa, H., Yamaguchi, N., Yamaguchi, N. | Biochem. Biophys. Res. Commun. 511 (4): 765-771 (2019). | 55034 | 30833073 |
Atg2 mediates direct lipid transfer between membranes for autophagosome formation. | Osawa, T., Kotani, T., Kawaoka, T., Hirata, E., Suzuki, K., Nakatogawa, H., Ohsumi, Y., Noda, N.N. | Nat. Struct. Mol. Biol. 26 (4): 281-288 (2019). | 55033 | 30911189 |
Single cell RNA-sequencing identified Dec2 as a suppressive factor for spermatogonial differentiation by inhibiting Sohlh1 expression. | Makino, Y., Jensen, N.H., Yokota, N., Rossner, M.J., Akiyama, H., Shirahige, K., Okada, Y. | Sci. Rep. 9 (1): 6063 (2019). | 55031 | 30988352 |
Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism. | Sasako, T., Ohsugi, M., Kubota, N., Itoh, S., Okazaki, Y., Terai, A., Kubota, T., Yamashita, S., Nakatsukasa, K., Kamura, T., Iwayama, K., Tokuyama, K., Kiyonari, H., Furuta, Y., Shibahara, J., Fukayama, M., Enooku, K., Okushin, K., Tsutsumi, T., Tateishi, R., Tobe, K., Asahara, H., Koike, K., Kadowaki, T., Ueki, K. | Nat. Commun. 10 (1): 947 (2019). | 55030 | 30814508 |
Mathematical analysis of gefitinib resistance of lung adenocarcinoma caused by MET amplification. | Ito, T., Kumagai, Y., Itano, K., Maruyama, T., Tamura, K., Kawasaki, S., Suzuki, T., Murakami ,Y. | Biochem. Biophys. Res. Commun. 511 (3): 544-550 (2019). | 55029 | 30824185 |
TEA Domain Transcription Factor 4 Is the Major Mediator of Yes-Associated Protein Oncogenic Activity in Mouse and Human Hepatoblastoma. | Zhang, J., Liu, P., Tao, J., Wang, P., Zhang, Y., Song, X., Che, L., Sumazin, P., Ribback, S., Kiss, A., Schaff, Z., Cigliano, A., Dombrowski, F., Cossu, C., Pascale, R.M., Calvisi, D.F., Monga, S.P., Chen, X. | Am. J. Pathol. pii: S0002-9440 (18) 30776-4 (2019). | 55028 | 30794805 |
Type I interferon protects neurons from prions in in vivo models. | Ishibashi, D., Homma, T., Nakagaki, T., Fuse, T., Sano, K., Satoh, K., Mori, T., Atarashi, R., Nishida, N. | Brain 142 (4): 1035-1050 (2019). | 55027 | 30753318 |
Type I interferon protects neurons from prions in in vivo models. | Ishibashi, D., Homma, T., Nakagaki, T., Fuse, T., Sano, K., Satoh, K., Mori, T., Atarashi, R., Nishida, N. | Brain 142 (4): 1035-1050 (2019). | 55027 | 30753318 |
Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats. | Goto, T., Hara, H., Sanbo, M., Masaki, H., Sato, H., Yamaguchi, T., Hochi, S., Kobayashi, T., Nakauchi, H., Hirabayashi, M. | Nat. Commun. 10 (1): 451 (2019). | 55026 | 30723213 |
Heat shock-induced mitotic arrest requires heat shock protein 105 for the activation of spindle assembly checkpoint. | Kakihana, A., Oto, Y., Saito, Y., Nakayama, Y. | FASEB J. 33 (3): 3936-3953 (2019). | 54549 | 30496702 |
NF-kappaB-induced NOX1 activation promotes gastric tumorigenesis through the expansion of SOX2-positive epithelial cells. | Echizen, K., Horiuchi, K., Aoki, Y., Yamada, Y., Minamoto, T., Oshima, H., Oshima, M. | Oncogene. 2019 Jan 30. doi: 10.1038/s41388-019-0702-0. [Epub ahead of print] | 54542 | 30700829 |
EphA2 phosphorylation at Ser897 by the Cdk1/MEK/ERK/RSK pathway regulates M-phase progression via maintenance of cortical rigidity. | Kaibori, Y., Saito, Y., Nakayama, Y. | FASEB J. 33 (4): 5334-5349 (2019). | 54541 | 30668924 |
Contribution of individual olfactory receptors to odor-induced attractive or aversive behavior in mice. | Horio, N., Murata, K., Yoshikawa, K., Yoshihara, Y., Touhara, K. | Nat. Commun. 10 (1): 209 (2019). | 54537 | 30643144 |
A method of producing genetically manipulated mouse mammary gland. | Tagaya, H., Ishikawa, K., Hosokawa, Y., Kobayashi, S., Ueoka, Y., Shimada, M., Ohashi, Y., Mikami, H., Yamamoto, M., Ihara, T., Kumazawa, K., Sugihara, K., Goshima, N., Watanabe, S., Semba, K. | Breast Cancer Res. 21 (1): 1 (2019). | 54536 | 30611295 |
Mitochondrial ribosomal protein PTCD3 mutations cause oxidative phosphorylation defects with Leigh syndrome. | Borna, N.N., Kishita, Y., Kohda, M., Lim, S.C., Shimura, M., Wu, Y., Mogushi, K., Yatsuka, Y., Harashima, H., Hisatomi, Y., Fushimi, T., Ichimoto, K., Murayama, K., Ohtake, A., Okazaki, Y. | Neurogenetics 20 (1): 9-25 (2019). | 54535 | 30607703 |
Novel GLI2 mutations identified in patients with Combined Pituitary Hormone Deficiency (CPHD): Evidence for a pathogenic effect by functional characterization. | Babu, D., Fanelli, A., Mellone, S., Muniswamy, R., Wasniewska, M., Prodam, F., Petri, A., Bellone, S., Salerno, M.C., Giordano, M. | Clin. Endocrinol. (Oxf). 90 (3): 449-456 (2019). | 54534 | 30548673 |
Yeast and human P4-ATPases transport glycosphingolipids using conserved structural motifs. | Roland, B.P., Naito, T., Best, J.T., Arnaiz-Yepez, C., Takatsu, H., Yu, R.J., Shin, H.W., Graham, T.R. | J. Biol. Chem. 294 (6): 1794-1806 (2019). | 54533 | 30530492 |
Off- and on-target effects of genome editing in mouse embryos. | Ayabe, S., Nakashima, K., Yoshiki, A. | J. Reprod. Dev. 65 (1): 1-5 (2019). | 54529 | 30518723 |
The nucleosome remodeling and deacetylase complex protein CHD4 regulates neural differentiation of mouse embryonic stem cells by down-regulating p53. | Hirota, A., Nakajima-Koyama, M., Ashida, Y., Nishida, E. | J. Biol. Chem. 294 (1): 195-209 (2019). | 54479 | 30409903 |
TAZ activation by Hippo pathway dysregulation induces cytokine gene expression and promotes mesothelial cell transformation. | Matsushita, A., Sato, T., Mukai, S., Fujishita, T., Mishiro-Sato, E., Okuda, M., Aoki, M., Hasegawa, Y., Sekido, Y. | Oncogene 38: 1966?1978 (2019). | 54478 | 30401981 |
Interactions of the dynein-2 intermediate chain WDR34 with the light chains are required for ciliary retrograde protein trafficking. | Tsurumi, Y., Hamada, Y., Katoh, Y., Nakayama, K. | Mol. Biol. Cell 16: mbcE18100678 (2019). | 54403 | 30649997 |
Desuppression of TGF-beta signaling via nuclear c-Abl-mediated phosphorylation of TIF1 gamma/TRIM33 at Tyr-524, -610, and -1048. | Yuki, R., Tatewaki, T., Yamaguchi, N., Aoyama, K., Honda, T., Kubota, S., Morii, M., Manabe, I., Kuga, T., Tomonaga, T., Yamaguchi, N. | Oncogene 38 (5): 637-655 (2019). | 54148 | 30177833 |
Characterization of cyanobacterial cells synthesizing 10-methyl stearic acid. | Machida, S., Suzuki, I. | Photosynth. Res. 139 (1-3): 173-183 (2019). | 53848 | 29943360 |
METHOD OF SCREENING ATP11C OR CDC50A INHIBITOR | Nagata, S., Segawa,K. | US Patent 2019/0242873, 2019 | 1443 |
2018
Title | Author | Journal | NBRP RRC ID | PubMed PMID |
---|---|---|---|---|
TAR DNA-Binding Protein 43 and Disrupted in Schizophrenia 1 Coaggregation Disrupts Dendritic Local Translation and Mental Function in Frontotemporal Lobar Degeneration. | Endo, R., Takashima, N., Nekooki-Machida, Y., Komi, Y., Hui, K.K-W., Takao, M., Akatsu, H., Murayama, S., Sawa, A., Tanaka, M. | Biol. Psychiatry. 84(7): 509-521 (2018). | 57435 | 29752072 |
KIR2DL4-HLAG interaction at human NK cell-oligodendrocyte interfaces regulates IFN-gamma-mediated effects. | Banerjee, P.P., Pang, L., Soldan, S.S., Miah, S.M., Eisenberg, A., Maru, S., Waldman, A., Smith, E.A., Rosenberg-Hasson, Y., Hirschberg, D., Smith, A., Ablashi, D.V., Campbell, K.S., Orange, J.S. | Mol. Immunol. pii: S0161-5890 (18) 30835-6 (2018). | 56705 | 30482463 |
Cell-to-Cell Heterogeneity in p38-Mediated Cross-Inhibition of JNK Causes Stochastic Cell Death. | Miura, H., Kondo, Y., Matsuda, M., Aoki, K. | Cell Rep. 24 (10): 2658-2668 (2018). | 56704 | 30184500 |
New neurons use Slit-Robo signaling to migrate through the glial meshwork and approach a lesion for functional regeneration. | Kaneko, N., Herranz-Perez, V., Otsuka, T., Sano, H., Ohno, N., Omata, T., Nguyen, H.B., Thai, T.Q., Nambu, A., Kawaguchi, Y., Garcia-Verdugo, J.M., Sawamoto, K. | Sci. Adv. 4 (12): eaav0618 (2018). | 55797 | 30547091 |
Efficient immortalization of cells derived from critically endangered Tsushima leopard cat (Prionailurus bengalensis euptilurus) with expression of mutant CDK4, Cyclin D1, and telomerase reverse transcriptase. | Gouko, R., Onuma, M., Eitsuka, T., Katayama, M., Takahashi, K., Nakagawa, K., Inoue-Murayama, M., Kiyono, T., Fukuda, T. | Cytotechnology 70 (6): 1619-1630 (2018). | 54547 | 30225752 |
Nrf2-mediated anti-oxidant effects contribute to suppression of non-alcoholic steatohepatitis-associated hepatocellular carcinoma in murine model. | Yamada, S., Kimura, M., Saito, Y., Saito, H. | J. Clin. Biochem. Nutr. \63 (2): 123-128 (2018). | 54546 | 30279623 |
Ribosome-induced RNA conformational changes in a viral 3′-UTR sense and regulate translation levels. | Hartwick, E.W., Costantino, D.A., MacFadden, A., Nix, J.C., Tian, S., Das, R., Kieft, J.S. | Nat. Commun. 9 (1): 5074 (2018). | 54506 | 30498211 |
Enhancing 3-hydroxypropionic acid production in combination with sugar supply engineering by cell surface-display and metabolic engineering of Schizosaccharomyces pombe. | Takayama, S., Ozaki, A., Konishi, R., Otomo, C., Kishida, M., Hirata, Y., Matsumoto, T., Tanaka, T., Kondo, A. | Microb. Cell Fact. 17 (1): 176 (2018). | 54482 | 30424766 |
Cellular density-dependent increases in HIF-1alpha compete with c-Myc to down-regulate human EP4 receptor promoter activity through Sp-1-binding region. | Seira, N., Yamagata, K., Fukushima, K., Araki, Y., Kurata, N., Yanagisawa, N., Mashimo, M., Nakamura, H., Regan, J.W., Murayama, T., Fujino, H. | Pharmacol. Res. Perspect. 6 (6): e00441 (2018). | 54481 | 30455960 |
USP10 Is a Driver of Ubiquitinated Protein Aggregation and Aggresome Formation to Inhibit Apoptosis. | Takahashi, M., Kitaura, H., Kakita, A., Kakihana, T., Katsuragi, Y., Nameta, M., Zhang, L., Iwakura, Y., Nawa, H., Higuchi, M., Komatsu, M., Fujii, M. | iScience 9: 433-450. (2018). | 54477 | 30469013 |
Acute HSF1 depletion induces cellular senescence through the MDM2-p53-p21 pathway in human diploid fibroblasts. | Oda, T., Sekimoto, T., Kurashima, K., Fujimoto, M., Nakai, A., Yamashita, T. | J. Cell Sci. 131 (9). pii: jcs210724 (2018). | 54411 | 29632240 |
Pol eta, a Y-family translesion synthesis polymerase, promotes cellular tolerance of Myc-induced replication stress. | Kurashima, K., Sekimoto, T., Oda, T., Kawabata, T., Hanaoka, F., Yamashita, T. | J. Cell Sci. 131 (12). pii: jcs212183 (2018). | 54410 | 29777036 |
Ubiquitin D is up-regulated by synergy of Notch signalling and TNF-alpha in the inflamed intestinal epithelia of IBD patients. | Kawamoto, A., Nagata, S., Anzai, S., Takahashi, J., Kawai, M., Hama, M., Nogawa, D., Yamamoto, K., Kuno, R., Suzuki, K., Shimizu, H., Hiraguri, Y., Yui, S., Ohshima, S., Tsuchiya, K., Nakamura, T., Ohtsuka, K., Kitagawa, M., Okamoto, R., Watanabe, M. | J Crohns Colitis. 2018 Nov 3. doi: 10.1093/ecco-jcc/jjy180. [Epub ahead of print] | 54388 | 30395194 |
Identification of the physiological substrates of PDIp, a pancreas-specific protein-disulfide isomerase family member. | Fujimoto, T., Nakamura, O., Saito, M., Tsuru, A., Matsumoto, M., Kohno, K., Inaba, K., Kadokura, H. | J. Biol. Chem. 293 (48): 18421-18433 (2018). | 54379 | 30315102 |
Activin E Controls Energy Homeostasis in Both Brown and White Adipose Tissues as a Hepatokine. | Hashimoto, O., Funaba, M., Sekiyama, K., Doi, S., Shindo, D., Satoh, R., Itoi, H., Oiwa, H., Morita, M., Suzuki, C., Sugiyama, M., Yamakawa, N., Takada, H., Matsumura, S., Inoue, K., Oyadomari, S., Sugino, H., Kurisaki, A. | Cell Rep. 25 (5): 1193-1203 (2018). | 54362 | 30380411 |
Development of mKO2 fusion proteins for real-time imaging and mechanistic investigation of the degradation kinetics of human IkappaBalpha in living cells. | Rahimova, N., Babazada, H., Higuchi, Y., Yamashita, F., Hashida, M. | Biochim. Biophys. Acta Mol. Cell Res. 1866 (2): 190-198 (2018). | 54361 | 30391277 |
Robust Enhancement of Lentivirus Production by Promoter Activation. | Suzuki, N., Yoshida, T., Takeuchi, H., Sakuma, R., Sukegawa, S., Yamaoka, S. | Sci. Rep. 8 (1): 15036 (2018). | 54331 | 30310119 |
Generation of orthotopically functional salivary gland from embryonic stem cells. | Tanaka, J., Ogawa, M., Hojo, H., Kawashima, Y., Mabuchi, Y., Hata, K., Nakamura, S., Yasuhara, R., Takamatsu, K., Irie, T., Fukada, T., Sakai, T., Inoue, T., Nishimura, R., Ohara, O., Saito, I., Ohba, S., Tsuji, T., Mishima, K. | Nat. Commun. 9 (1): 4216 (2018). | 54330 | 30310071 |
Single-Unit Imaging of Membrane Protein-Embedded Nanodiscs from Two Oriented Sides by High-Speed Atomic Force Microscopy. | Haruyama, T., Sugano, Y., Kodera, N., Uchihashi, T., Ando, T., Tanaka, Y., Konno, H., Tsukazaki, T. | Structure pii: S0969-2126 (18) 30331-9 (2018). | 54329 | 30318467 |
Human Sox4 facilitates the development of CXCL13-producing helper T cells in inflammatory environments. | Yoshitomi, H., Kobayashi, S., Miyagawa-Hayashino, A., Okahata, A., Doi, K., Nishitani, K., Murata, K., Ito, H., Tsuruyama, T., Haga, H., Matsuda, S., Toguchida, J. | Nat. Commun. 9 (1): 3762 (2018). | 54228 | 30232328 |
SIRT2-mediated inactivation of p73 is required for glioblastoma tumorigenicity. | Funato, K., Hayashi, T., Echizen, K., Negishi, L., Shimizu, N., Koyama-Nasu, R., Nasu-Nishimura, Y., Morishita, Y., Tabar, V., Todo, T., Ino, Y., Mukasa, A., Saito, N., Akiyama, T. | EMBO Rep. 19 (11). pii: e45587 (2018). | 54227 | 30213795 |
Forkhead box protein A1 confers resistance to transforming growth factor-beta-induced apoptosis in breast cancer cells through inhibition of Smad3 nuclear translocation. | Hirata, K., Takakura, Y., Shibazaki, M., Morii, M., Honda, T., Oshima, M., Aoyama, K., Iwama, A., Nakayama, Y., Takano, H., Yamaguchi, N., Yamaguchi, N. | J Cell Biochem. 2018 Sep 11. doi: 10.1002/jcb.27551. [Epub ahead of print] | 54226 | 30206966 |
Role of leukotriene B4 12-hydroxydehydrogenase in α-galactosylceramide-pulsed dendritic cell therapy for non-small cell lung cancer. | Tanaka, K., Kanesaka, Y., Takami, M., Suzuki, A., Hosokawa, H., Onodera, A., Kamata, T., Nagato, K., Nakayama, T., Yoshino, I., Motohashi, S. | Biochem. Biophys. Res. Commun. 506 (1): 27-32 (2018). | 54149 | 30336981 |
Repression of Somatic Genes by Selective Recruitment of HDAC3 by BLIMP1 Is Essential for Mouse Primordial Germ Cell Fate Determination. | Mochizuki, K., Hayashi, Y., Sekinaka, T., Otsuka, K., Ito-Matsuoka, Y., Kobayashi, H., Oki, S., Takehara, A., Kono, T., Osumi, N., Matsui, Y. | Cell Rep. 24 (10): 2682-2693.e6 (2018). | 54147 | 30184502 |
CFAP70 Is a Novel Axoneme-Binding Protein That Localizes at the Base of the Outer Dynein Arm and Regulates Ciliary Motility. | Shamoto, N., Narita, K., Kubo, T., Oda, T., Takeda, S. | Cells 7 (9). pii: E124 (2018). | 54146 | 30158508 |
Sensing of Escherichia coli and LPS by mammary epithelial cells is modulated by O-antigen chain and CD14. | Vedrine, M., Berthault, C., Leroux, C., Reperant-Ferter, M., Gitton, C., Barbey, S., Rainard, P., Gilbert, F.B., Germon, P. | PLoS One 13 (8): e0202664 (2018). | 54145 | 30142177 |
Chemogenetic Approach Using Ni(II) Complex-Agonist Conjugates Allows Selective Activation of Class A G-Protein-Coupled Receptors. | Kubota, R., Nomura, W., Iwasaka, T., Ojima, K., Kiyonaka, S., Hamachi, I. | ACS Cent. Sci. 4 (9): 1211-1221 (2018). | 54144 | 30276255 |
Tmc2 expression partially restores auditory function in a mouse model of DFNB7/B11 deafness caused by loss of Tmc1 function. | Nakanishi, H., Kurima, K., Pan, B., Wangemann, P., Fitzgerald, T.S., Geleoc, G.S., Holt. J.R., Griffith, A.J. | Sci. Rep. 8 (1): 12125 (2018). | 53919 | 30108230 |
Poly(ADP-ribose) polymerase-2 is a lipid-modulated modulator of muscular lipid homeostasis. | Marton, J., Peter, M., Balogh, G., Bodi, B., Vida, A., Szanto, M., Bojcsuk, D., Janko, L., Bhattoa, H.P., Gombos, I., Uray, K., Horvath, I., Torok, Z., Balint, B.L., Papp, Z., Vigh, L., Bai, P. | Biochim. Biophys. Acta Mol. Cell. Biol. Lipids pii: S1388-1981 (18) 30187-2 (2018). | 53915 | 30077797 |
Integration Mapping of piggyBac-Mediated CD19 Chimeric Antigen Receptor T Cells Analyzed by Novel Tagmentation-Assisted PCR. | Hamada, M., Nishio, N., Okuno, Y., Suzuki, S., Kawashima, N., Muramatsu, H., Tsubota, S., Wilson, M.H., Morita, D., Kataoka, S., Ichikawa, D., Murakami, N., Taniguchi, R., Suzuki, K., Kojima, D., Sekiya, Y., Nishikawa, E., Narita, A., Hama, A., Kojima, S., Nakazawa, Y., Takahashi, Y. | EBioMedicine 34: 18-26 (2018). | 53914 | 30082227 |
In silico drug screening by using genome-wide association study data repurposed dabrafenib, an anti-melanoma drug, for Parkinson’s disease. | Uenaka, T., Satake, W., Cha, P.C., Hayakawa, H., Baba, K., Jiang, S., Kobayashi, K., Kanagawa, M., Okada, Y., Mochizuki, H., Toda, T. | Hum. Mol. Genet. 27 (22): 3974-3985 (2018). | 53913 | 30137437 |
Lysine-specific demethylase 1 inhibitors prevent teratoma development from human induced pluripotent stem cells. | Osada, N., Kikuchi, J., Umehara, T., Sato, S., Urabe, M., Abe, T., Hayashi, N., Sugitani, M., Hanazono, Y., Furukawa, Y. | Oncotarget 9 (5): 6450-6462 (2018). | 53912 | 29464084 |
MicroRNA-101 inhibits the expression of Rhes, a striatal-enriched small G-protein, at the post-transcriptional level in vitro. | Mizuno, H., Taketomi, A. | BMC Res. Notes 11 (1): 528 (2018) | 53894 | 30064488 |
Live cell imaging of X chromosome reactivation during somatic cell reprogramming. | Tran, T.H.Y., Fukuda, A., Aizawa, S., Bui, P.L., Hayashi, Y., Nishimura, K., Hisatake, K. | Biochem. Biophys. Rep. 15: 86-92 (2018). | 53893 | 30094351 |
Interaction of LEF1 with TAZ is necessary for the osteoblastogenic activity of Wnt3a. | Kida, J., Hata, K., Nakamura, E., Yagi, H., Takahata, Y., Murakami, T., Maeda, Y., Nishimura, R. | Sci. Rep. 8 (1): 10375 (2018). | 53876 | 29991769 |
Schizosaccharomyces pombe cardiolipin synthase is part of a mitochondrial fusion protein regulated by intron retention. | Vircikova, V., Pokorna L., Tahotna, D., Dzugasova, V., Balazova, M., Griac, P. | Biochim Biophys Acta pii: S1388-1981 (18) 30146-X (2018). | 53860 | 29958934 |
Expression of human mutant cyclin dependent kinase 4, Cyclin D and telomerase extends the life span but does not immortalize fibroblasts derived from loggerhead sea turtle (Caretta caretta). | Fukuda, T., Eitsuka, T., Donai, K., Kurita, M., Saito, T., Okamoto, H., Kinoshita, K., Katayama, M., Nitto, H., Uchida, T., Onuma, M., Sone, H., Inoue-Murayama, M., Kiyono, T. | Sci. Rep. 8 (1): 9229 (2018). | 53847 | 29925962 |
A platform of BRET-FRET hybrid biosensors for optogenetics, chemical screening, and in vivo imaging. | Komatsu, N., Terai, K., Imanishi, A., Kamioka, Y., Sumiyama, K., Jin, T., Okada, Y., Nagai, T., Matsuda, M. | Sci. Rep. 8 (1): 8984 (2018). | 53846 | 29895862 |
Map7/7D1 and Dvl form a feedback loop that facilitates microtubule remodeling and Wnt5a signaling. | Kikuchi, K., Nakamura, A., Arata, M., Shi, D., Nakagawa, M., Tanaka, T., Uemura, T., Fujimori, T., Kikuchi, A., Uezu, A., Sakamoto, Y., Nakanishi, H. | EMBO Rep. 19 (7). pii: e45471 (2018). | 53836 | 29880710 |
Bacterial EndoMS/NucS acts as a clamp-mediated mismatch endonuclease to prevent asymmetric accumulation of replication errors. | Takemoto, N., Numata, I., Su’etsugu, M., Miyoshi-Akiyama, T. | Nucleic Acids Res. 46 (12): 6152-6165 (2018). | 53829 | 29878158 |
Composite regulation of ERK activity dynamics underlying tumour-specific traits in the intestine. | Muta, Y., Fujita, Y., Sumiyama, K., Sakurai, A., Taketo, M.M., Chiba, T., Seno, H., Aoki, K., Matsuda, M., Imajo, M. | Nat. Commun. 9 (1): 2174 (2018). | 53828 | 29872037 |
Corynebacterium kroppenstedtii in granulomatous mastitis: Analysis of formalin-fixed, paraffin-embedded biopsy specimens by immunostaining using low-specificity bacterial antisera and real-time polymerase chain reaction. | Fujii, M., Mizutani, Y., Sakuma, T., Tagami, K., Okamoto, K., Kuno, Y., Harada, M., Kubouchi, K., Tsutsumi, Y. | Pathol. Int. 68 (7): 409-418 (2018). | 53827 | 29862601 |
Interaction of WDR60 intermediate chain with TCTEX1D2 light chain of the dynein-2 complex is crucial for ciliary protein trafficking. | Hamada, Y., Tsurumi, Y., Nozaki, S., Katoh, Y., Nakayama, K. | Mol. Biol. Cell 29 (13): 1628-1639 (2018). | 53819 | 29742051 |
Interaction of heterotrimeric kinesin-II with IFT-B-connecting tetramer is crucial for ciliogenesis. | Funabashi, T., Katoh, Y., Okazaki, M., Sugawa, M., Nakayama, K. | J. Cell Biol. 217 (8): 2867-2876 (2018). | 53203 | 29903877 |
Hypoxic stress up-regulates Kir2.1 expression by a pathway including hypoxic-inducible factor-1 and dynamin2 in brain capillary endothelial cells. | Yamamura, H., Suzuki, Y., Yamamura, H., Asai, K., Giles, W., Imaizumi, Y. | Am. J. Physiol. Cell Physiol. 315 (2): C202-C213 (2018). | 52896 | 29768048 |
Relationship Between Homodimeric Glucocorticoid Receptor and Transcriptional Regulation Assessed via an In Vitro Fluorescence Correlation Spectroscopy-Microwell System. | Oasa, S., Mikuni, S., Yamamoto, J., Kurosaki, T., Yamashita, D., Kinjo, M. | Sci. Rep. 8 (1): 7488 (2018). | 52895 | 29748590 |
RUNX1 positively regulates the ErbB2/HER2 signaling pathway through modulating SOS1 expression in gastric cancer cells. | Mitsuda, Y., Morita, K., Kashiwazaki, G., Taniguchi, J., Bando, T., Obara, M., Hirata, M., Kataoka, T.R., Muto, M., Kaneda, Y., Nakahata, T., Liu, P.P., Adachi, S., Sugiyama, H., Kamikubo, Y. | Sci. Rep. 8 (1): 6423 (2018). | 52893 | 29686309 |
Overexpression of HER2 in the pancreas promotes development of intraductal papillary mucinous neoplasms in mice. | Shibata, W., Kinoshita, H., Hikiba, Y., Sato, T., Ishii, Y., Sue, S., Sugimori, M., Suzuki, N., Sakitani, K., Ijichi, H., Mori, R., Endo, I., Maeda, S. | Sci. Rep. 8 (1): 6150 (2018). | 52889 | 29670173 |
Detection of high CD44 expression in oral cancers using the novel monoclonal antibody, C44Mab-5. | Yamada, S., Itai, S., Nakamura, T., Yanaka, M., Kaneko, M.K., Kato, Y. | Biochem. Biophys. Rep. 14: 64-68 (2018). | 52888 | 29872736 |
Generation of TCR-Expressing Innate Lymphoid-like Helper Cells that Induce Cytotoxic T Cell-Mediated Anti-leukemic Cell Response. | Ueda, N., Uemura, Y., Zhang, R., Kitayama, S., Iriguchi, S., Kawai, Y., Yasui, Y., Tatsumi, M., Ueda, T., Liu, T.Y., Mizoro, Y., Okada, C., Watanabe, A., Nakanishi, M., Senju, S., Nishimura, Y., Kuzushima, K., Kiyoi, H., Naoe, T., Kaneko, S. | Stem Cell Reports 10 (6): 1935-1946 (2018). | 52879 | 29805109 |
Application of auxin-inducible degron technology to mouse oocyte activation with PLCzeta. | Miura, K., Matoba, S., Ogonuki, N., Namiki, T., Ito, J., Kashiwazaki, N., Ogura, A. | J. Reprod. Dev. 64 (4): 319-326 (2018). | 51575 | 29731504 |
The poly-cistronic expression of four transcriptional factors (CRX, RAX, NEURO-D, OTX2) in fibroblasts via retro- or lentivirus causes partial reprogramming into photoreceptor cells. | Fukuda, T., Ishizawa, Y., Donai, K., Sugano, E., Tomita, H. | Cell Biol. Int. 42 (5): 608-614 (2018). | 51322 | 29377330 |
Elavl3 is essential for the maintenance of Purkinje neuron axons. | Ogawa, Y., Kakumoto, K., Yoshida, T., Kuwako, K.I., Miyazaki, T., Yamaguchi, J., Konno, A., Hata, J., Uchiyama, Y., Hirai, H., Watanabe, M., Darnell, R.B., Okano, H., Okano, H.J. | Sci. Rep. 8 (1): 2722 (2018). | 51321 | 29426875 |
Internalization of CD239 highly expressed in breast cancer cells: a potential antigen for antibody-drug conjugates. | Kikkawa, Y., Enomoto-Okawa, Y., Fujiyama, A., Fukuhara, T., Harashima, N., Sugawara, Y., Negishi, Y., Katagiri, F., Hozumi, K., Nomizu, M., Ito, Y. | Sci. Rep. 8 (1): 6612 (2018). | 51309 | 29700410 |
CLICK: one-step generation of conditional knockout mice. | Miyasaka, Y., Uno, Y., Yoshimi, K., Kunihiro, Y., Yoshimura, T., Tanaka, T., Ishikubo, H., Hiraoka, Y., Takemoto, N., Tanaka, T., Ooguchi, Y., Skehel, P., Aida, T., Takeda, J., Mashimo, T. | BMC Genomics 19 (1): 318 (2018). | 51308 | 29720086 |
Gasdermin D Exerts Anti-inflammatory Effects by Promoting Neutrophil Death. | Kambara, H., Liu, F., Zhang, X., Liu, P., Bajrami, B., Teng, Y., Zhao, L., Zhou, S., Yu, H., Zhou, W., Silberstein, L.E., Cheng, T., Han, M., Xu, Y., Luo, H.R. | Cell Rep. 22 (11): 2924-2936 (2018). | 51235 | 29539421 |
In Vivo Genetic Manipulation of Spermatogonial Stem Cells and Their Microenvironment by Adeno-Associated Viruses. | Watanabe, S., Kanatsu-Shinohara, M., Ogonuki, N., Matoba, S., Ogura, A., Shinohara, T. | Stem Cell Reports 10 (5): 1551-1564 (2018). | 50638 | 29628393 |
Comprehensive Analysis of a cis-Regulatory Region Reveals Pleiotropy in Enhancer Function. | Preger-Ben Noon, E., Sabaris, G., Ortiz, D.M., Sager, J., Liebowitz, A., Stern, D.L., Frankel, N. | Cell Rep. 22 (11): 3021-3031 (2018). | 50635 | 29539428 |
PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth. | Morita, M., Sato, T., Nomura, M., Sakamoto, Y., Inoue, Y., Tanaka, R., Ito, S., Kurosawa, K., Yamaguchi, K., Sugiura, Y., Takizaki, H., Yamashita, Y., Katakura, R., Sato, I., Kawai, M., Okada, Y., Watanabe, H., Kondoh, G., Matsumoto, S., Kishimoto, A., Obata, M., Matsumoto, M., Fukuhara, T., Motohashi, H., Suematsu, M., Komatsu, M., Nakayama, K.I., Watanabe, T., Soga, T., Shima, H., Maemondo, M., Tanuma, N. | Cancer Cell 33 (3): 355-367.e7 (2018). | 50634 | 29533781 |
RUNX transcription factors potentially control E-selectin expression in the bone marrow vascular niche in mice. | Morita, K., Tokushige, C., Maeda, S., Kiyose, H., Noura, M., Iwai, A., Yamada, M., Kashiwazaki, G., Taniguchi, J., Bando, T., Hirata, M., Kataoka, T.R., Nakahata, T., Adachi, S., Sugiyama, H., Kamikubo, Y. | Blood Adv. 2 (5): 509-515 (2018). | 50624 | 29500219 |
Regulation of granulocyte colony-stimulating factor receptor-mediated granulocytic differentiation by C-mannosylation. | Otani, K., Niwa, Y., Suzuki, T., Sato, N., Sasazawa, Y., Dohmae, N., Simizu, S. | Biochem. Biophys. Res. Commun. 498 (3): 466-472 (2018). | 50622 | 29501745 |
enChIP systems using different CRISPR orthologues and epitope tags. | Fujita, T., Yuno, M., Fujii, H. | BMC Res. Notes 11 (1): 154 (2018). | 50614 | 29482606 |
EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase. | Kasahara, K., Aoki, H., Kiyono, T., Wang, S., Kagiwada, H., Yuge, M., Tanaka, T., Nishimura, Y., Mizoguchi, A., Goshima, N., Inagaki, M. | Nat. Commun. 9 (1): 758 (2018). | 50463 | 29472535 |
Glutamate-cysteine ligase catalytic subunit is associated with cisplatin resistance in lung adenocarcinoma. | Hiyama, N., Ando, T., Maemura, K., Sakatani, T., Amano, Y., Watanabe, K., Kage, H., Yatomi, Y., Nagase, T., Nakajima, J., Takai, D. | Jpn. J. Clin. Oncol. 48 (4): 303-307 (2018). | 50462 | 29474642 |
Fatty Acid Binding Protein 4 (FABP4) Overexpression in Intratumoral Hepatic Stellate Cells within Hepatocellular Carcinoma with Metabolic Risk Factors. | Chiyonobu, N., Shimada, S., Akiyama, Y., Mogushi, K., Itoh, M., Akahoshi, K., Matsumura, S., Ogawa, K., Ono, H., Mitsunori, Y., Ban, D., Kudo, A., Arii, S., Suganami, T., Yamaoka, S., Ogawa, Y., Tanabe, M., Tanaka, S. | Am. J. Pathol. 188 (5): 1213-1224 (2018). | 50461 | 29454748 |
Trogocytosis of ligand-receptor complex and its intracellular transport in CD30 signalling. | Nakashima, M., Watanabe, M., Uchimaru, K., Horie, R. | Biol. Cell 110 (5): 109-124 (2018). | 50332 | 29431186 |
Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in Macrophages | Karasawa, T., Kawashima, A., Usui-Kawanishi, F., Watanabe, S., Kimura, H., Kamata, R., Shirasuna, K., Koyama, Y., Sato-Tomita, A., Matsuzaka, T., Tomoda, H., Park, S.Y., Shibayama, N., Shimano, H., Kasahara, T., Takahashi, M. | Arterioscler. Thromb. Vasc. Biol. 38 (4): 744-756 (2018). | 50300 | 29437575 |
Myeloma Cells are Activated in Bone Marrow Microenvironment by the CD180/MD-1 Complex which Senses Lipopolysaccharide. | Kikuchi, J., Kuroda, Y., Koyama, D., Osada, N., Izumi, T., Yasui, H., Kawase, T., Ichinohe, T., Furukawa, Y. | Cancer Res. 78 (7): 1766-1778 (2018). | 50076 | 29363546 |
The Cullin-3-Rbx1-KCTD10 complex controls endothelial barrier function via K63 ubiquitination of RhoB. | Kova?evi?. I., Sakaue, T., Majolee, J., Pronk, M.C., Maekawa, M., Geerts, D., Fernandez-Borja, M., Higashiyama, S., Hordijk, P.L. | J. Cell Biol. 217 (3): 1015-1032 (2018). | 50075 | 29358211 |
Radial Glial Fibers Promote Neuronal Migration and Functional Recovery after Neonatal Brain Injury. | Jinnou, H., Sawada, M., Kawase, K., Kaneko, N., Herranz-Perez, V., Miyamoto, T., Kawaue, T., Miyata, T., Tabata. Y., Akaike, T., Garcia-Verdugo, J.M., Ajioka, I., Saitoh, S., Sawamoto, K. | Cell Stem Cell 22 (1): 128-137.e9. (2018). | 50074 | 29276142 |
TUFT1 interacts with RABGAP1 and regulates mTORC1 signaling | Kawasaki, N., Isogaya, K., Dan, S., Yamori, T., Takano, H., Yao, R., Morishita, Y., Taguchi, L., Morikawa, M., Heldin, C.H. Noda, T., Ehata, S., Miyazono, K., Koinuma, D. | Cell Discovery 4 (1): (2018). | 50065 | 29423269 |
Arsenite-induced histone H3 modification and its effects on EGR1 and FOS expression in HeLa cells. | Suzuki, T., Watanabe, H., Kita, K., Honma, T., Ochi, T. | J. Appl. Toxicol. 38 (5): 734-743 (2018) | 50039 | 29350772 |
Development of intestinal M cells and follicle-associated epithelium is regulated by TRAF6-mediated NF-κB signaling. | Kanaya, T., Sakakibara, S., Jinnohara, T., Hachisuka, M., Tachibana, N., Hidano, S., Kobayashi, T., Kimura, S., Iwanaga, T., Nakagawa, T., Katsuno, T., Kato, N., Akiyama, T., Sato, T., Williams, I.R., Ohno, H. | J. Exp. Med. 215 (2): 501-519 (2018). | 50038 | 29339448 |
Pde6brd1 mutation modifies cataractogenesis in Foxe3rct mice. | Wada, K., Saito, J., Yamaguchi, M., Seki, Y., Furugori, M., Takahashi, G., Nishito, Y., Matsuda, H., Shitara, H., Kikkawa, Y. | Biochem. Biophys. Res. Commun. 496 (1): 231-237 (2018). | 50037 | 29317205 |
The RNA-splicing endonuclease from the euryarchaeaon Methanopyrus kandleri is a heterotetramer with constrained substrate specificity. | Kaneta, A., Fujishima, K., Morikazu, W., Hori, H., Hirata, A. | Nucleic. Acids. Res. 46 (4): 1958-1972 (2018). | 50036 | 29346615 |
Online measurement of the respiratory activity in shake flasks enables the identification of cultivation phases and patterns indicating recombinant protein production in various E. coli host strains. | Ihling, N., Bittner, N., Diederichs, S., Schelden, M., Korona, A., Hofler, G.T., Fulton, A., Jaeger, K.E., Honda, K., Ohtake, H., Buchs, J. | Biotechnol. Prog. 34 (2): 315-327 (2018). | 50031 | 29314728 |
The CDC50A extracellular domain is required for forming a functional complex with and chaperoning phospholipid flippases to the plasma membrane. | Segawa, K., Kurata, S., Nagata, S. | J. Biol. Chem. 293 (6): 2172-2182 (2018). | 50029 | 29276178 |
Potential usefulness of Brevibacillus for bacterial cancer therapy: intratumoral provision of tumor necrosis factor-α and anticancer effects. | Mukai, H., Takahashi, M., Watanabe, Y. | Cancer Gene Ther. 25(3-4): 47-57 (2018). | 50027 | 29255215 |
A Refined Culture System for Human Induced Pluripotent Stem Cell-Derived Intestinal Epithelial Organoids. | Takahashi, Y., Sato, S., Kurashima, Y., Yamamoto, T., Kurokawa, S., Yuki, Y., Takemura, N., Uematsu, S., Lai, C.Y., Otsu, M., Matsuno, H., Osawa, H., Mizushima, T., Nishimura, J., Hayashi, M., Yamaguchi, T., Kiyono, H. | Stem Cell Reports 10 (1): 314-328 (2018). | 50020 | 29233552 |
Physiological role of urothelial cancer-associated one long noncoding RNA in human skeletogenic cell differentiation. | Ishikawa, T., Nishida, T., Ono, M., Takarada, T., Nguyen, H.T., Kurihara, S., Furumatsu, T., Murase, Y., Takigawa, M., Oohashi, T., Kamioka, H., Kubota, S. | J. Cell. Physiol. 233 (6): 4825-4840 (2018). | 50016 | 29150954 |
Development of a rapid and quantitative method for the analysis of viral entry and release using a NanoLuc luciferase complementation assay. | Sasaki, M., Anindita, P.D., Phongphaew, W., Carr, M., Kobayashi, S., Orba, Y., Sawa, H. | Virus Res. 243: 69-74 (2018). | 49649 | 29074234 |
Novel biallelic mutations in the PNPT1 gene encoding a mitochondrial-RNA-import protein PNPase cause delayed myelination. | Sato, R., Arai-Ichinoi, N., Kikuchi, A., Matsuhashi, T., Numata-Uematsu, Y., Uematsu, M., Fujii, Y., Murayama, K., Ohtake, A., Abe, T., Kure, S. | Clin. Genet. 93 (2): 242-247 (2018). | 49236 | 28594066 |
2017
Title | Author | Journal | NBRP RRC ID | PubMed PMID |
---|---|---|---|---|
Radiosensitivity of quiescent and proliferating cells grown as multicellular tumor spheroids. | Onozato, Y., Kaida, A., Harada, H., Miura, M. | Cancer Sci. 108 (4): 704-712 (2017). | 57376 | 28135769 |
Noncanonical Pathway for Regulation of CCL2 Expression by an mTORC1-FOXK1 Axis Promotes Recruitment of Tumor-Associated Macrophages. | Nakatsumi, H., Matsumoto, M., Nakayama, K.I. | Cell Rep. 21 (9): 2471-2486 (2017). | 56703 | 29186685 |
Long-term maintenance of peripheral blood derived human NK cells in a novel human IL-15- transgenic NOG mouse. | Katano, I., Nishime, C., Ito, R., Kamisako, T., Mizusawa, T., Ka, Y., Ogura, T., Suemizu, H., Kawakami, Y., Ito, M., Takahashi, T. | Sci. Rep. 7 (1): 17230 (2017). | 55032 | 29222435 |
RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination. | Inano, S., Sato, K., Katsuki, Y., Kobayashi, W., Tanaka, H., Nakajima, K., Nakada, S., Miyoshi, H., Knies, K., Takaori-Kondo, A., Schindler, D., Ishiai, M., Kurumizaka, H., Takata, M. | Mol. Cell 66 (5): 622-634.e8 (2017). | 54484 | 28575658 |
Adoptive Cellular Gene Therapy for the Treatment of Experimental Autoimmune Polychondritis Ear Disease. | Zhou, B., Liao, Y., Guo, Y., Tarner, I.H., Liao, C., Chen, S., Kermany, M.H., Tu, H., Zhong, S., Chen, P. | ORL J. Otorhinolaryngol. Relat. Spec. 79 (3): 166-177 (2017). | 51319 | 28463837 |
Requirement of Hsp105 in CoCl2-induced HIF-1α accumulation and transcriptional activation. | Mikami, H., Saito, Y., Okamoto, N., Kakihana, A., Kuga, T., Nakayama, Y. | Exp. Cell Res. 352 (2): 225-233 (2017). | 51318 | 28185835 |
A novel method to generate single-cell-derived cancer-associated fibroblast clones. | Hashimoto, H., Suda, Y., Miyashita, T., Ochiai, A., Tsuboi, M., Masutomi, K., Kiyono, T., Ishii, G. | J. Cancer Res. Clin. Oncol. 143 (8): 1409-1419 (2017). | 51316 | 28364361 |
Notch Inhibitors from Calotropis gigantea That Induce Neuronal Differentiation of Neural Stem Cells. | Yoneyama, T., Arai, M.A., Akamine, R., Koryudzu, K., Tsuchiya, A., Sadhu, S.K., Ahmed, F., Itoh, M., Okamoto, R., Ishibashi, M. | J. Nat. Prod. 80 (9): 2453-2461 (2017). | 51315 | 28817274 |
Paradoxical enhancement of leukemogenesis in acute myeloid leukemia with moderately attenuated RUNX1 expressions. | Morita, K., Maeda, S., Suzuki, K., Kiyose, H., Taniguchi, J., Liu, P.P., Sugiyama, H., Adachi, S., Kamikumo, Y. | Blood Adv. 1: 1440-1451 (2017). | 51314 | 29296785 |
Functional Pituitary Tissue Formation Recapitulating Hypothalamus and Pituitary Development Using ES/iPS Cells. | Suga, H., Ozone, C. | Organ Regeneration Based on Developmental Biology pp 41-56. | 51313 | |
A cell-based high-throughput screening assay system for inhibitor compounds of antigen presentation by HLA class II molecule. | Watanabe, N., Suzuki, Y., Yonezu, T., Nakagawa, Y., Shiina, T., Hirayama, N., Inokuchi, S., Inoue, S. | Sci. Rep. 7 (1): 6798 (2017). | 50081 | 28754892 |
Neurocan, an extracellular chondroitin sulfate proteoglycan, stimulates neuroblastoma cells to promote malignant phenotypes. | Su, Z., Kishida, S., Tsubota, S., Sakamoto, K., Cao, D., Kiyonari, S., Ohira, M., Kamijo, T., Narita, A., Xu, Y., Takahashi, Y., Kadomatsu, K. | Oncotarget 8 (63): 106296-106310 (2017). | 50028 | 29290949 |
A genetic screen to discover SUMOylated proteins in living mammalian cells. | Komiya, M., Ito, A., Endo, M., Hiruma, D., Hattori, M., Saitoh, H., Yoshida, M., Ozawa, T. | Sci. Rep. 7 (1): 17443 (2017). | 50025 | 29234079 |
RUNX1 regulates site specificity of DNA demethylation by recruitment of DNA demethylation machineries in hematopoietic cells. | Suzuki, T., Shimizu, Y., Furuhata, E., Maeda, S., Kishima, M., Nishimura, H., Enomoto, S., Hayashizaki, Y., Suzuki, H. | Blood Adv. 1 (20): 1699-1711 (2017). | 50019 | 29296817 |
Autonomous feedback loop of RUNX1-p53-CBFB in acute myeloid leukemia cells. | Morita, K., Noura, M., Tokushige, C., Maeda, S., Kiyose, H., Kashiwazaki, G., Taniguchi, J., Bando, T., Yoshida, K., Ozaki, T., Matsuo, H., Ogawa, S., Liu, P.P., Nakahata, T., Sugiyama, H., Adachi, S., Kamikubo, Y. | Sci. Rep. 7 (1): 16604 (2017). | 50018 | 29192243 |
Direct conversion of human fibroblasts into hepatocyte-like cells by ATF5, PROX1, FOXA2, FOXA3, and HNF4A transduction. | Nakamori, D., Akamine, H., Takayama, K., Sakurai, F., Mizuguchi, H. | Sci. Rep. 7 (1): 16675 (2017). | 50017 | 29192290 |
TALEN-mediated shift of mitochondrial DNA heteroplasmy in MELAS-iPSCs with m.13513G>A mutation. | Yahata, N., Matsumoto, Y., Omi, M., Yamamoto, N., Hata, R. | Sci. Rep. 7 (1): 15557 (2017). | 50015 | 29138463 |
Circadian clock regulates hepatic polyploidy by modulating Mkp1-Erk1/2 signaling pathway. | Chao, H.W., Doi, M., Fustin, J.M., Chen, H., Murase, K., Maeda, Y., Hayashi, H., Tanaka, R., Sugawa, M., Mizukuchi, N., Yamaguchi, Y., Yasunaga, J.I., Matsuoka, M., Sakai, M., Matsumoto, M., Hamada, S., Okamura, H. | Nat. Commun. 8 (1): 2238 (2017). | 50014 | 29269828 |
Significance of dopamine D1 receptor signalling for steroidogenic differentiation of human induced pluripotent stem cells. | Matsuo, K., Sone, M., Honda-Kohmo, K., Toyohara, T., Sonoyama, T., Taura, D., Kojima, K., Fukuda, Y., Ohno, Y., Inoue, M., Ohta, A., Osafune, K., Nakao, K., Inagaki, N. | Sci. Rep. 7 (1): 15120 (2017). | 49725 | 29123220 |
Propagating Wave of ERK Activation Orients Collective Cell Migration. | Aoki, K., Kondo, Y., Naoki, H., Hiratsuka, T., Itoh, R.E., Matsuda, M. | Dev. Cell 43 (3): 305-317.e5 (2017). | 49724 | 29112851 |
Expression of Genes for a Flavin Adenine Dinucleotide-Binding Oxidoreductase and a Methyltransferase from Mycobacterium chlorophenolicum Is Necessary for Biosynthesis of 10-Methyl Stearic Acid from Oleic Acid in Escherichia coli. | Machida, S., Bakku, R.K., Suzuki, I. | Front. Microbiol. 8: 2061 (2017). | 49723 | 29109716 |
Fibroblasts promote the collective invasion of ameloblastoma tumor cells in a 3D coculture model. | Fuchigami, T., Koyama, H., Kishida, M., Nishizawa, Y., Iijima, M., Kibe, T., Ueda, M., Kiyono, T., Maniwa, Y., Nakamura, N., Kishida, S. | FEBS Open Bio. 7 (12): 2000-2007 (2017). | 49721 | 29226086 |
NK Cell Alloreactivity against KIR-Ligand-Mismatched HLA-Haploidentical Tissue Derived from HLA Haplotype-Homozygous iPSCs. | Ichise, H., Nagano, S., Maeda, T., Miyazaki, M., Miyazaki, Y., Kojima, H., Yawata, N., Yawata, M., Tanaka, H., Saji, H., Masuda, K., Kawamoto, H. | Stem Cell Reports 9 (3): 853-867 (2017). | 49718 | 28867344 |
Metabolic engineering of Schizosaccharomyces pombe via CRISPR-Cas9 genome editing for lactic acid production from glucose and cellobiose. | Ozaki, A., Konishi, R., Otomo, C., Kishida, M., Takayama, S., Matsumoto, T., Tanaka, T., Kondo, A. | Metab. Eng. Commun. 5: 60-67 (2017). | 49575 | 29188185 |
CRISPR-Cas9-based photoactivatable transcription systems to induce neuronal differentiation. | Nihongaki, Y., Furuhata, Y., Otabe, T., Hasegawa, S., Yoshimoto, K., Sato, M. | Nat. Methods 14 (10): 963-966 (2017). | 49561 | 28892089 |
FAD influx enhances neuronal differentiation of human neural stem cells by facilitating nuclear localization of LSD1. | Hirano, K., Namihira, M. | FEBS Open Bio. 7 (12): 1932-1942 (2017). | 49559 | 29226080 |
ARIH2 Ubiquitinates NLRP3 and Negatively Regulates NLRP3 Inflammasome Activation in Macrophages. | Kawashima, A., Karasawa, T., Tago, K., Kimura, H., Kamata, R., Usui-Kawanishi, F., Watanabe, S., Ohta, S., Funakoshi-Tago, M., Yanagisawa, K., Kasahara, T., Suzuki, K., Takahashi, M. | J. Immunol. 199 (10): 3614-3622 (2017). | 49558 | 29021376 |
Eudesmane-Type Sesquiterpene Lactones Inhibit Nuclear Translocation of the Nuclear Factor kappaB Subunit RelB in Response to a Lymphotoxin beta Stimulation. | Quach, H.T., Kondo, T., Watanabe, M., Tamura, R., Yajima, Y., Sayama, S., Ando, M., Kataoka, T. | Biol. Pharm. Bull. 40 (10): 1669-1677 (2017). | 49556 | 28966239 |
Reciprocal Inflammatory Signaling Between Intestinal Epithelial Cells and Adipocytes in the Absence of Immune Cells. | Takahashi, Y., Sato, S., Kurashima, Y., Lai, C.Y., Otsu, M., Hayashi, M., Yamaguchi, T., Kiyono, H. | EBioMedicine. 23: 34-45 (2017). | 49555 | 28789943 |
Mouse macrophages show different requirements for phosphatidylserine receptor Tim4 in efferocytosis. | Yanagihashi, Y., Segawa, K., Maeda, R., Nabeshima, Y., Nagata, S. | Proc. Natl. Acad. Sci. U.S.A. 114 (33): 8800-8805 (2017). | 49554 | 28768810 |
Astrocyte calcium waves propagate proximally by gap junction and distally by extracellular diffusion of ATP released from volume-regulated anion channels. | Fujii, Y., Maekawa, S., Morita, M. | Sci. Rep. 7 (1): 13115 (2017). | 49531 | 29030562 |
A Role for KLF4 in Promoting the Metabolic Shift via TCL1 during Induced Pluripotent Stem Cell Generation. | Nishimura, K., Aizawa, S., Nugroho, F.L., Shiomitsu, E., Tran, Y.T., Bui, P.L., Borisova, E., Sakuragi, Y., Takada, H., Kurisaki, A., Hayashi, Y., Fukuda, A., Nakanishi, M., Hisatake, K. | Stem Cell Reports 8 (3): 787-801 (2017). | 49491 | 28262547 |
Creation of mutant mice with megabase-sized deletions containing custom-designed breakpoints by means of the CRISPR/Cas9 system. | Kato, T., Hara, S., Goto, Y., Ogawa, Y., Okayasu, H., Kubota, S., Tamano, M., Terao, M., Takada, S. | Sci. Rep. 7 (1): 59 (2017). | 49490 | 28246396 |
HMGA1 regulates the Plasminogen activation system in the secretome of breast cancer cells. | Resmini, G., Rizzo, S., Franchin, C., Zanin, R., Penzo, C., Pegoraro, S., Ciani, Y., Piazza, S., Arrigoni, G., Sgarra, R., Manfioletti, G. | Sci. Rep. 7 (1): 11768 (2017). | 49319 | 28924209 |
A Long Noncoding RNA, lncRNA-Amhr2, Plays a Role in Amhr2 Gene Activation in Mouse Ovarian Granulosa Cells. | Kimura, A.P., Yoneda, R., Kurihara, M., Mayama, S., Matsubara, S. | Endocrinology 158 (11): 4105-4121 (2017). | 49318 | 28938492 |
Human SMOOTHENED inhibits human immunodeficiency virus type 1 infection. | Yoshida, T., Hamano, A., Ueda, A., Takeuchi, H., Yamaoka, S. | Biochem. Biophys. Res. Commun. 493 (1): 132-138 (2017). | 49317 | 28917838 |
The parathyroid hormone regulates skin tumour susceptibility in mice. | Okumura, K., Saito, M., Yoshizawa, Y., Munakata, H., Isogai, E., Miura, I., Wakana, S., Yamaguchi, M., Shitara, H., Taya, C., Karaplis, A.C., Kominami, R., Wakabayashi, Y. | Sci. Rep. 7 (1): 11208 (2017). | 49316 | 28894263 |
PM01183 inhibits myeloid-derived suppressor cells in vitro and in vivo. | Kuroda, H., Mabuchi, S., Kozasa, K., Yokoi, E., Matsumoto, Y., Komura, N., Kawano, M., Hashimoto, K., Sawada, K., Kimura, T. | Immunotherapy 9 (10): 805-817 (2017). | 49279 | 28877631 |
Enhancement of TGF-beta-induced Smad3 activity by c-Abl-mediated tyrosine phosphorylation of its coactivator SKI-interacting protein (SKIP). | Kuki, K., Yamaguchi, N., Iwasawa, S., Takakura, Y., Aoyama, K., Yuki, R., Nakayama, Y., Kuga, T., Hashimoto, Y., Tomonaga, T., Yamaguchi, N. | Biochem. Biophys. Res. Commun. 490 (3): 1045-1051 (2017). | 49278 | 28666867 |
A Key Enzyme of the NAD+ Salvage Pathway in Thermus thermophilus: Characterization of Nicotinamidase and the Impact of Its Gene Deletion at High Temperatures. | Taniguchi, H., Sungwallek, S., Chotchuang, P., Okano, K., Honda, K. | J. Bacteriol. 199 (17). pii: e00359-17 (2017). | 49277 | 28630126 |
ZEB1-regulated inflammatory phenotype in breast cancer cells. | Katsura, A., Tamura, Y., Hokari, S., Harada, M., Morikawa, M., Sakurai, T., Takahashi, K., Mizutani, A., Nishida, J., Yokoyama, Y., Morishita, Y., Murakami, T., Ehata, S., Miyazono, K., Koinuma, D. | Mol. Oncol. 11 (9): 1241-1262 (2017). | 49276 | 28618162 |
A novel nuclear complex of DRR1, F-actin and COMMD1 involved in NF-κB degradation and cell growth suppression in neuroblastoma. | Mu, P., Akashi, T., Lu, F., Kishida, S., Kadomatsu, K. | Oncogene 36 (41): 5745-5756 (2017). | 49275 | 28604741 |
ALK signaling cascade confers multiple advantages to glioblastoma cells through neovascularization and cell proliferation. | Chiba, R., Akiya, M., Hashimura, M., Oguri, Y., Inukai, M., Hara, A., Saegusa, M. | PLoS One 12 (8): e0183516 (2017). | 49267 | 28837676 |
Overexpression of C-type Natriuretic Peptide in Endothelial Cells Protects against Insulin Resistance and Inflammation during Diet-induced Obesity. | Bae, C.R., Hino, J., Hosoda, H., Arai, Y., Son, C., Makino, H., Tokudome, T., Tomita, T., Kimura, T., Nojiri, T., Hosoda, K., Miyazato, M., Kangawa, K. | Sci. Rep. 7 (1): 9807 (2017). | 49261 | 28852070 |
Direct reprogramming of fibroblasts into skeletal muscle progenitor cells by transcription factors enriched in undifferentiated subpopulation of satellite cells. | Ito, N., Kii, I., Shimizu, N., Tanaka, H., Shin’ichi, T. | Sci. Rep. 7 (1): 8097 (2017). | 49256 | 28808339 |
Ypt4 and lvs1 regulate vacuolar size and function in Schizosaccharomyces pombe. | Rains, A., Bryant, Y., Dorsett, K.A., Culver, A., Egbaria, J., Williams, A., Barnes, M., Lamere, R., Rossi, A.R., Waldrep, S.C., Wilder, C., Kliossis, E., Styers, M.L. | Cellular Logistics, 7 (3): e1335270 (2017). | 49238 | 28944093 |
Single-molecule fluorescence imaging of RalGDS on cell surfaces during signal transduction from Ras to Ral. | Yoshizawa, R., Umeki, N., Yanagawa, M., Murata, M., Sako, Y. | Biophys. Physicobiol. 14: 75-84 (2017). | 49235 | 28744424 |
Genetic regulation of the RUNX transcription factor family has antitumor effects. | Morita, K., Suzuki. K., Maeda, S., Matsuo, A., Mitsuda, Y., Tokushige, C., Kashiwazaki, G., Taniguchi, J., Maeda, R., Noura, M., Hirata, M., Kataoka, T., Yano, A., Yamada, Y., Kiyose, H., Tokumasu, M., Matsuo, H., Tanaka, S., Okuno, Y., Muto, M., Naka, K., Ito, K., Kitamura, T., Kaneda, Y., Liu, P.P., Bando, T., Adachi, S., Sugiyama, H., Kamikubo, Y. | J. Clin. Invest. 127 (7): 2815-2828 (2017). | 49234 | 28530640 |
Activating transcription factor 6-dependent sestrin 2 induction ameliorates ER stress-mediated liver injury. | Jegal, K.H., Park, S.M., Cho, S.S., Byun, S.H., Ku, S.K., Kim, S.C., Ki, S.H., Cho, I.J. | Biochim. Biophys. Acta 1864 (7): 1295-1307 (2017). | 49233 | 28433684 |
MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1. | Shichita, T., Ito, M., Morita, R., Komai, K., Noguchi, Y., Ooboshi, H., Koshida, R., Takahashi, S., Kodama, T., Yoshimura, A. | Nat. Med. 23 (6): 723-732 (2017). | 49232 | 28394332 |
CCAAT/enhancer-binding protein alpha decreases the viability of gastric cancer cells. | Tomizawa, M., Shinozaki, F., Motoyoshi, Y., Sugiyama, T., Yamamoto, S., Ishige, N. | Oncol. Lett. 13 (6): 4322-4326 (2017). | 49231 | 28599433 |
PU.1 acts as tumor suppressor for myeloma cells through direct transcriptional repression of IRF4. | Ueno, N., Nishimura, N., Ueno, S., Endo, S., Tatetsu, H., Hirata, S., Hata, H., Matsuoka, M., Mitsuya, H., Okuno, Y. | Oncogene 36 (31): 4481-4497 (2017). | 49230 | 28368411 |
RUNX1 induces DNA replication independent active DNA demethylation at SPI1 regulatory regions | Goyal, S., Suzuki, T., Li, J.R., Maeda, S., Kishima, M., Nishimura, H., Shimizu, Y., Suzuki, H. | BMC Mol. Biol. 18 (1): 9 (2017). | 49229 | 28376714 |
Immortalized prairie vole-derived fibroblasts (VMF-K4DTs) can be transformed into pluripotent stem cells and provide a useful tool with which to determine optimal reprogramming conditions. | Katayama, M., Hirayama, T., Kiyono, T., Onuma, M., Tani, T., Takeda, S., Nishimori, K., Fukuda, T. | J. Reprod. Dev. 63 (3): 311-318 (2017). | 49216 | 28331164 |
GLI-mediated Keratin 17 expression promotes tumor cell growth through the anti-apoptotic function in oral squamous cell carcinomas. | Mikami, Y., Fujii, S., Nagata, K., Wada, H., Hasegawa, K., Abe, M., Yoshimoto, R.U., Kawano, S., Nakamura, S., Kiyoshima, T. | J. Cancer Res. Clin. Oncol. 143 (8): 1381-1393 (2017). | 49215 | 28342001 |
Tumor necrosis factor-alpha inhibits differentiation of myogenic cells in human urethral rhabdosphincter. | Shinohara, M., Sumino, Y., Sato, F., Kiyono, T., Hashimoto, N., Mimata, H. | Int. J. Urol. 24 (6): 461-467 (2017). | 49214 | 28332237 |
Establishment and characterization of cell lines derived from complete hydatidiform mole. | Yamamoto, E., Niimi, K., Kiyono, T., Yamamoto, T., Nishino, K., Nakamura, K., Kotani, T., Kajiyama, H., Shibata, K., Kikkawa, F. | Int. J. Mol. Med. 40 (3): 614-622 (2017). | 48886 | 28713902 |
Aggregation of scaffolding protein DISC1 dysregulates phosphodiesterase 4 in Huntington’s disease. | Tanaka, M., Ishizuka, K., Nekooki-Machida, Y., Endo, R., Takashima, N., Sasaki, H., Komi, Y., Gathercole, A., Huston, E., Ishii, K., Hui, K.K., Kurosawa, M., Kim, S.H., Nukina, N., Takimoto, E., Houslay, M.D., Sawa, A. | J. Clin. Invest. 127 (4): 1438-1450 (2017). | 48884 | 28263187 |
Fibroblast-led cancer cell invasion is activated by epithelial-mesenchymal transition through platelet-derived growth factor BB secretion of lung adenocarcinoma. | Neri, S., Miyashita, T., Hashimoto, H., Suda, Y., Ishibashi, M., Kii, H., Watanabe, H., Kuwata, T., Tsuboi, M., Goto, K., Menju, T., Sonobe, M., Date, H., Ochiai, A., Ishii, G. | Cancer Lett. 395: 20-30 (2017). | 48883 | 28286261 |
Bacterial Sphingomyelinase is a State-Dependent Inhibitor of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR). | Stauffer, B.B., Cui, G., Cottrill, K.A., Infield, D.T., McCarty, N.A. | Sci. Rep. 7 (1): 2931 (2017). | 48841 | 28592822 |
A Glycopeptidyl-Glutamate Epimerase for Bacterial Peptidoglycan Biosynthesis. | Feng, R., Satoh, Y., Ogasawara, Y., Yoshimura, T., Dairi, T. | J. Am. Chem. Soc. 139 (12): 4243-4245 (2017). | 48834 | 28294606 |
A noncoding RNA containing a SINE-B1 motif associates with meiotic metaphase chromatin and has an indispensable function during spermatogenesis. | Nakajima, R., Sato, T., Ogawa, T., Okano, H., Noce, T. | PLoS One 12 (6): e0179585 (2017). | 48833 | 28658256 |
Genetically encoded bioluminescent voltage indicator for multi-purpose use in wide range of bioimaging. | Inagaki, S., Tsutsui, H., Suzuki, K., Agetsuma, M., Arai, Y., Jinno, Y., Bai, G., Daniels, M.J., Okamura, Y., Matsuda, T., Nagai, T. | Sci. Rep. 7: 42398 (2017). | 48814 | 28205521 |
The CUL3-SPOP-DAXX axis is a novel regulator of VEGFR2 expression in vascular endothelial cells. | Sakaue, T., Sakakibara, I., Uesugi, T., Fujisaki, A., Nakashiro, K.I., Hamakawa, H., Kubota, E., Joh, T., Imai, Y.K., Izutani, H., Higashiyama, S. | Sci. Rep. 7: 42845 (2017). | 48813 | 28216678 |
An aging-independent replicative lifespan in a symmetrically dividing eukaryote. | Spivey, E.C., Jones, S.K., Rybarski, J.R., Saifuddin, F.A., Finkelstein, I.J. | Elife 6. pii: e20340 (2017). | 48806 | 28139976 |
Deoxynucleoside Salvage in Fission Yeast Allows Rescue of Ribonucleotide Reductase Deficiency but Not Spd1-Mediated Inhibition of Replication. | Fleck, O., Fahnoe, U., Lovschal, K.V., Gasasira, M.U., Marinova, I.N., Kragelund, B.B., Carr, A.M., Hartsuiker, E., Holmberg, C., Nielsen, O. | Genes (Basel). 8 (5). pii: E128 (2017). | 48805 | 28441348 |
UBL/BAG-domain co-chaperones cause cellular stress upon overexpression through constitutive activation of Hsf1. | Poulsen, E.G., Kampmeyer, C., Kriegenburg, F., Johansen, J.V., Hofmann, K., Holmberg, C., Hartmann-Petersen, R. | Cell Stress Chaperones 22 (1): 143-154 (2017). | 48804 | 27966061 |
LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells. | Gu, M., LaJoie, D., Chen, O.S., von Appen, A., Ladinsky, M.S., Redd, M.J., Nikolova, L., Bjorkman, P.J., Sundquist, W.I., Ullman, K.S., Frost, A. | Proc. Natl. Acad. Sci. U.S.A. 114 (11): E2166-E2175 (2017). | 48803 | 28242692 |
SUMO-Targeted DNA Translocase Rrp2 Protects the Genome from Top2-Induced DNA Damage. | Wei, Y., Diao, L.X., Lu, S., Wang, H.T., Suo, F., Dong, M.Q., Du, L.L. | Mol. Cell 66 (5): 581-596 (2017). | 48799 | 28552615 |
APC Mutations as a Potential Biomarker for Sensitivity to Tankyrase Inhibitors in Colorectal Cancer. | Tanaka, N., Mashima, T., Mizutani, A., Sato, A., Aoyama, A., Gong, B., Yoshida, H., Muramatsu, Y., Nakata, K., Matsuura, M., Katayama, R., Nagayama, S., Fujita, N., Sugimoto, Y., Seimiya, H. | Mol. Cancer Ther. 16 (4): 752-762 (2017). | 48798 | 28179481 |
Sulfated glycosaminoglycans and non-classically secreted proteins, basic FGF and epimorphin, coordinately regulate TGF-beta-induced cell behaviors of human scar dermal fibroblasts. | Horigome, T., Takumi, S., Shirai, K., Kido, T., Hagiwara-Chatani, N., Nakashima, A., Adachi, N., Yano, H., Hirai, Y. | J. Dermatol. Sci. 86 (2): 132-141 (2017). | 48797 | 28209294 |
Genome-wide screen for cell growth regulators in fission yeast. | Weston, L., Greenwood, J., Nurse, P. | J. Cell Sci. 130 (12): 2049-2055 (2017). | 48764 | 28476936 |
Chromatin Domain Organization of the TCRb Locus and Its Perturbation by Ectopic CTCF Binding. | Rawat, P., Jalan, M., Sadhu, A., Kanaujia, A., Srivastava, M. | Mol. Cell. Biol. 37 (9). pii: e00557-16 (2017). | 48758 | 28137913 |
Mast Cells Are Crucial for Induction of Group 2 Innate Lymphoid Cells and Clearance of Helminth Infections. | Shimokawa, C., Kanaya, T., Hachisuka, M., Ishiwata, K., Hisaeda, H., Kurashima, Y., Kiyono, H., Yoshimoto, T., Kaisho, T., Ohno, H. | Immunity 46 (5): 863-874 (2017). | 48562 | 28514691 |
Transgenic Monkey Model of the Polyglutamine Diseases Recapitulating Progressive Neurological Symptoms. | Tomioka, I., Ishibashi, H., Minakawa, E.N., Motohashi, H.H., Takayama, O., Saito, Y., Popiel, H.A., Puentes, S., Owari, K., Nakatani, T., Nogami, N., Yamamoto, K., Noguchi, S., Yonekawa, T., Tanaka, Y., Fujita, N., Suzuki, H., Kikuchi, H., Aizawa, S., Nagano, S., Yamada, D., Nishino, I., Ichinohe, N., Wada, K., Kohsaka, S., Nagai, Y., Seki, K. | eNeuro 4 (2). pii: ENEURO.0250-16 (2017). | 48562 | 28374014 |
Estimation of the influence of sequencing errors and distribution of random-sequence tags on quantitative sequencing. | Hoshino, T., Hamada, Y. | J. Biosci. Bioeng. pii: S1389-1723 (17) 30077-30074 (2017). | 48084 | 28457659 |
Specific glutamic acid residues in targeted proteins induce exaggerated retardations in Phos-tag SDS-PAGE migration. | Kinoshita, E., Kinoshita-Kikuta, E., Karata, K., Kawano, T., Nishiyama, A., Yamato, M., Koike, T. | Electrophoresis 38 (8): 1139-1146 (2017). | 47981 | 28112428 |
Efficient induction of dopaminergic neuron differentiation from induced pluripotent stem cells reveals impaired mitophagy in PARK2 neurons. | Suzuki, S., Akamatsu, W., Kisa, F., Sone, T., Ishikawa, K.I., Kuzumaki, N., Katayama, H., Miyawaki, A., Hattori, N., Okano, H. | Biochem. Biophys. Res. Commun. 483 (1): 88-93 (2017). | 47980 | 28057485 |
CD200-positive cancer associated fibroblasts augment the sensitivity of Epidermal Growth Factor Receptor mutation-positive lung adenocarcinomas to EGFR Tyrosine kinase inhibitors. | Ishibashi, M., Neri, S., Hashimoto, H., Miyashita, T., Yoshida, T., Nakamura, Y., Udagawa, H., Kirita, K., Matsumoto, S., Umemura, S., Yoh, K., Niho, S., Tsuboi, M., Masutomi, K., Goto, K., Ochiai, A., Ishii, G. | Sci. Rep. 7: 46662 (2017). | 47979 | 28429795 |
Tandem UIMs confer Lys48 ubiquitin chain substrate preference to deubiquitinase USP25. | Kawaguchi, K., Uo, K., Tanaka, T., Komada, M. | Sci. Rep. 7: 45037 (2017). | 47938 | 28327663 |
Application of Stochastic Labeling with Random-Sequence Barcodes for Simultaneous Quantification and Sequencing of Environmental 16S rRNA Genes. | Hoshino, T., Inagaki, F. | PLoS One 12 (1): e0169431 (2017). | 47733 | 28052139 |
Mutation in VPS33A affects metabolism of glycosaminoglycans: a new type of mucopolysaccharidosis with severe systemic symptoms. | Kondo, H., Maksimova, N., Otomo, T., Kato, H., Imai, A., Asano, Y., Kobayashi, K., Nojima, S., Nakaya, A., Hamada, Y., Irahara, K., Gurinova, E., Sukhomyasova, A., Nogovicina, A., Savvina, M., Yoshimori, T., Ozono, K., Sakai, N. | Hum. Mol. Genet. 26 (1): 173-183 (2017). | 47720 | 28013294 |
Hepatocyte Nuclear Factor 4 Alpha Promotes Definitive Endoderm Differentiation from Human Induced Pluripotent Stem Cells. | Hanawa, M., Takayama, K., Sakurai, F., Tachibana, M., Mizuguchi, H. | Stem Cell Rev. 13 (4): 542-551 (2017). | 47718 | 28000155 |
Interleukin-8 enhances the effect of colchicine on cell death. | Yokoyama, C., Yajima, C., Machida, T., Kawahito, Y., Uchida, M., Hisatomi, H. | Biochem. Biophys. Res. Commun. 485 (1): 89-94 (2017). | 47632 | 28189686 |
Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting. | Chen, Q., Osada, K., Ge, Z., Uchida, S., Tockary, T.A., Dirisala, A., Matsui, A., Toh, K., Takeda, K.M., Liu, X., Nomoto, T., Ishii, T., Oba, M., Matsumoto, Y., Kataoka, K. | Biomaterials 113: 253-265 (2017). | 47498 | 27835820 |
Intraflagellar transport-A complex mediates ciliary entry and retrograde trafficking of ciliary G protein-coupled receptors. | Hirano, T., Katoh, Y., Nakayama, K. | Mol. Biol. Cell 28 (3): 429-439 (2017). | 47487 | 27932497 |
Characterization of cytopathic factors through genome-wide analysis of the Zika viral proteins in fission yeast. | Li, G., Poulsen, M., Fenyvuesvolgyi, C., Yashiroda, Y., Yoshida, M., Simard, J.M., Gallo, R.C., Zhao, R.Y. | Proc. Natl. Acad. Sci. U.S.A. 114 (3): E376-E385 (2017). | 47477 | 28049830 |
Establishment of expression-state boundaries by Rif1 and Taz1 in fission yeast. | Toteva, T., Mason, B., Kanoh, Y., Brogger, P., Green, D., Verhein-Hansen, J., Masai, H., Thon, G. | Proc. Natl. Acad. Sci. U.S.A. 114 (5): 1093-1098 (2017). | 47471 | 28096402 |
Expression of Tim-1 in primary CNS lymphoma. | Kishimoto, W., Nishikori, M., Arima, H., Miyoshi, H., Sasaki, Y., Kitawaki, T., Shirakawa, K., Kato, T., Imaizumi, Y., Ishikawa, T., Ohno, H., Haga, H., Ohshima, K., Takaori-Kondo, A. | Cancer Med. 5 (11): 3235-3245 (2017). | 47458 | 27709813 |
miR-663a regulates growth of colon cancer cells, after administration of antimicrobial peptides, by targeting CXCR4-p21 pathway. | Kuroda, K., Fukuda, T., Krstic-Demonacos, M., Demonacos, C., Okumura, K., Isogai, H., Hayashi, M., Saito, K., Isogai, E. | BMC Cancer 17 (1): 33 (2017). | 47457 | 28061765 |
Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46-IFT56 as well as on its nuclear localization signal. | Funabashi, T., Katoh, Y., Michisaka, S., Terada, M., Sugawa, M., Nakayama, K. | Mol. Biol. Cell 28 (5): 624-633 (2017). | 47456 | 28077622 |
Expression of Six Proteins Causes Reprogramming of Porcine Fibroblasts into Induced Pluripotent Stem Cells with Both Active X Chromosomes. | Fukuda, T., Tani, T., Haraguchi, S., Donai, K., Nakajima, N., Uenishi, H., Eitsuka, T., Miyagawa, M., Song, S., Onuma, M., Hoshino, Y., Sato, E., Honda, A. | J. Cell Biochem. 118(3): 537-553 (2017). | 45801 | 27608441 |
Clinical Significance of Histone Demethylase NO66 in Invasive Colorectal Cancer. | Nishizawa, Y., Nishida, N., Konno, M., Kawamoto, K., Asai, A., Koseki, J., Takahashi, H., Haraguchi, N., Nishimura, J., Hata, T., Matsuda, C., Mizushima, T., Satoh, T., Doki, Y., Mori, M., Ishii, H. | Ann. Surg. Oncol. 24 (3): 841-849 (2017). | 41310 | 27473587 |
2016
Title | Author | Journal | NBRP RRC ID | PubMed PMID |
---|---|---|---|---|
TGF-beta induces the differentiation of human CXCL13-producing CD4(+) T cells. | Kobayashi, S., Watanabe, T., Suzuki, R., Furu, M., Ito, H., Ito, J., Matsuda, S., Yoshitomi, H. | Eur. J. Immunol. 46 (2): 360-371 (2016). | 54505 | 26541894 |
Essential role of autoactivation circuitry on Aurora B-mediated H2AX-pS121 in mitosis. | Shimada, M., Goshima, T., Matsuo, H., Johmura, Y., Haruta, M., Murata, K., Tanaka, H., Ikawa, M., Nakanishi, K., Nakanishi, M. | Nat. Commun. 7: 12059 (2016). | 54485 | 27389782 |
FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5′-DNA end. | Sato, K., Shimomuki, M., Katsuki, Y., Takahashi, D., Kobayashi, W., Ishiai, M., Miyoshi, H., Takata, M., Kurumizaka, H. | Nucleic Acids Res. 44 (22): 10758-10771 (2016). | 54483 | 27694619 |
Detailed analysis of inversions predicted between two human genomes: errors, real polymorphisms, and their origin and population distribution. | Vicente-Salvador, D., Puig, M., Gaya-Vidal, M., Pacheco, S., Giner-Delgado, C., Noguera, I., Izquierdo, D., Martinez-Fundichely, A., Ruiz-Herrera, A., Estivill, X., Aguado, C., Lucas-Lledo, J.I., Caceres, M. | Hum. Mol. Genet 26 (3): 567-581 (2016). | 51327 | 28025331 |
Development of New Formulation Dry Powder for Pulmonary Delivery Using Amino Acids to Improve Stability. | Suzuki, Y., Okuda, T., Okamoto, H. | Biol. Pharm. Bull. 39 (3): 394-400 (2016). | 51326 | 26725531 |
Cellular conservation of endangered midget buffalo (Lowland Anoa, Bubalus quarlesi) by establishment of primary cultured cell, and its immortalization with expression of cell cycle regulators. | Fukuda, T., Iino, Y., Eitsuka, T., Onuma, M., Katayama, M., Murata, K., Inoue-Murayama, M., Hara, K., Isogai, E., Kiyono, T. | Cytotechnology 68 (5): 1937-1947 (2016). | 50078 | 27449922 |
Rab8b Regulates Transport of West Nile Virus Particles from Recycling Endosomes. | Kobayashi, S., Suzuki, T., Kawaguchi, A., Phongphaew, W., Yoshii, K., Iwano, T., Harada, A., Kariwa, H., Orba, Y., Sawa, H. | J. Biol. Chem. 291 (12): 6559-6568 (2016). | 49650 | 26817838 |
ASBEL-TCF3 complex is required for the tumorigenicity of colorectal cancer cells. | Taniue, K., Kurimoto, A., Takeda, Y., Nagashima, T., Okada-Hatakeyama, M., Katou, Y., Shirahige, K., Akiyama, T. | Proc. Natl. Acad. Sci. U.S.A. 113 (45): 12739?12744 (2016). | 49217 | 27791078 |
CSL protein regulates transcription of genes required to prevent catastrophic mitosis in fission yeast. | P?evorovsky, M., Oravcova, M., Zach, R., Jordakova, A., Bahler, J., P?ta, F., Folk P. | Cell Cycle 15 (22): 3082-3093 (2016). | 48807 | 27687771 |
Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis. | Kawashima, S.A., Chen, Z., Aoi, Y., Patgiri, A., Kobayashi, Y., Nurse, P., Kapoor, T.M. | Cell 167 (2): 512-524 (2016). | 48802 | 27667686 |
Engineering an ABC transporter for enhancing resistance to caffeine in Saccharomyces cerevisiae. | Wang, M., Deng, W.W., Zhang, Z.Z., Yu, O. | J Agric Food Chem. 64 (42): 7973?7978 (2016). | 48801 | 27696877 |
Centromere localization and function of Mis18 requires Yippee-like domain-mediated oligomerization. | Subramanian, L., Medina-Pritchard, B., Barton, R., Spiller, F., Kulasegaran-Shylini, R., Radaviciute, G., Allshire, R.C., Arockia Jeyaprakash, A. | EMBO Rep. 17 (4):496-507 (2016). | 48800 | 26921242 |
Importance of Hepatocyte Nuclear Factor 4α in Glycerol-induced Glucose-6-phosphatase Expression in Liver. | Yoshida, M., Lee, E.Y., Kohno, T., Tanaka, T., Miyazaki, M., Miki, T. | Biomed. Res. 37 (2): 85-93 (2016). | 48757 | 27108878 |
A Gastrointestinal Calpain Complex, G-calpain, Is a Heterodimer of CAPN8 and CAPN9 Calpain Isoforms, Which Play Catalytic and Regulatory Roles, Respectively. | Hata, S., Kitamura, F., Yamaguchi, M., Shitara, H., Murakami, M., Sorimachi, H. | J. Biol. Chem. 291 (53): 27313-27322 (2016). | 48551 | 27881674 |
Cell-Surface Protein Profiling Identifies Distinctive Markers of Progenitor Cells in Human Skeletal Muscle. | Uezumi, A., Nakatani, M., Ikemoto-Uezumi, M., Yamamoto, N., Morita, M., Yamaguchi, A., Yamada, H., Kasai, T., Masuda, S., Narita, A., Miyagoe-Suzuki, Y., Takeda, S., Fukada, S., Nishino, I., Tsuchida, K. | Stem Cell Reports 7 (2): 263-278 (2016). | 48087 | 27509136 |
An easy method for preparation of Cre-loxP regulated fluorescent adenoviral expression vectors and its application for direct reprogramming into hepatocytes. | Kurihara, C., Nakade, K., Pan, J., Huang, J., Wasylyk, B., Obata, Y. | Biotechnol. Rep. (Amst.) 12: 26-32 (2016). | 48009 | 28352551 |
USP10 Is an Essential Deubiquitinase for Hematopoiesis and Inhibits Apoptosis of Long-Term Hematopoietic Stem Cells. | Higuchi, M., Kawamura, H., Matsuki, H., Hara, T., Takahashi, M., Saito, S., Saito, K., Jiang, S., Naito, M., Kiyonari, H., Fujii, M. | Stem Cell Reports 7 (6): 1116-1129 (2016). | 47911 | 27974222 |
CKAP4 is a Dickkopf1 receptor and is involved in tumor progression. | Kimura, H., Fumoto, K., Shojima, K., Nojima, S., Osugi, Y., Tomihara, H., Eguchi, H., Shintani, Y., Endo, H., Inoue, M., Doki, Y., Okumura, M., Morii, E., Kikuchi, A. | J. Clin. Invest. 126 (7): 2689-2705 (2016). | 47732 | 27322059 |
Myc/Mycn-mediated glycolysis enhances mouse spermatogonial stem cell self-renewal. | Kanatsu-Shinohara, M., Tanaka, T., Ogonuki, N., Ogura, A., Morimoto, H., Cheng, P.F., Eisenman, R.N., Trumpp, A., Shinohara, T. | Genes Dev. 30 (23): 2637-2648 (2016). | 47719 | 28007786 |
Dormant Pluripotent Cells Emerge during Neural Differentiation of Embryonic Stem Cells in a FoxO3-Dependent Manner. | Ikeda, M., Toyoshima, F. | Mol. Cell. Biol. 37 (5). pii: e00417-16 (2016). | 47717 | 27956699 |
Intravital imaging of mouse urothelium reveals activation of extracellular signal-regulated kinase by stretch-induced intravesical release of ATP. | Sano, T., Kobayashi, T., Negoro, H., Sengiku, A., Hiratsuka, T., Kamioka, Y., Liou, L.S., Ogawa, O., Matsuda, M. | Physiol. Rep. 4 (21). pii: e13033 (2016). | 47634 | 27905300 |
Intercellular Coupling of the Cell Cycle and Circadian Clock in Adult Stem Cell Culture. | Matsu-Ura, T., Dovzhenok, A., Aihara, E., Rood, J., Le, H., Ren, Y., Rosselot, A.E., Zhang, T., Lee, C., Obrietan, K., Montrose, M.H., Lim, S., Moore, S.R., Hong, C.I. | Mol. Cell 64 (5): 900-912 (2016). | 47633 | 27867006 |
FUS interacts with nuclear matrix-associated protein SAFB1 as well as Matrin3 to regulate splicing and ligand-mediated transcription. | Yamaguchi, A., Takanashi, K. | Sci. Rep. 6: 35195 (2016). | 47497 | 27731383 |
Leishmania Uses Mincle to Target an Inhibitory ITAM Signaling Pathway in Dendritic Cells that Dampens Adaptive Immunity to Infection. | Iborra, S., Martinez-Lopez, M., Cueto, F.J., Conde-Garrosa, R., Del Fresno, C., Izquierdo, H.M., Abram, C.L., Mori, D., Campos-Martin, Y., Reguera, R.M., Kemp, B., Yamasaki, S., Robinson, M.J., Soto, M., Lowell, C.A., Sancho, D. | Immunity 45 (4): 788-801 (2016). | 47496 | 27742545 |
The phospholipid flippase ATP9A is required for the recycling pathway from the endosomes to the plasma membrane. | Tanaka, Y., Ono, N., Shima, T., Tanaka, G., Katoh, Y., Nakayama, K., Takatsu, H., Shin, H.W. | Mol. Biol. Cell 27 (24): 3883-3893 (2016). | 47495 | 27733620 |
Structural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide. | Omura, H., Oikawa, D., Nakane, T., Kato, M., Ishii, R., Ishitani, R., Tokunaga, F., Nureki, O. | Sci. Rep. 6: 34756 (2016). | 47494 | 27721487 |
Bright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging. | Shcherbakova, D.M., Baloban, M., Emelyanov, A.V., Brenowitz, M., Guo, P., Verkhusha, V.V. | Nat. Commun. 7: 12405 (2016). | 47488 | 27539380 |
Overall Architecture of the Intraflagellar Transport (IFT)-B Complex Containing Cluap1/IFT38 as an Essential Component of the IFT-B Peripheral Subcomplex. | Katoh, Y., Terada, M., Nishijima, Y., Takei, R., Nozaki, S., Hamada, H., Nakayama, K. | J. Biol. Chem. 291 (21): 10962-10975 (2016). | 47486 | 26980730 |
Evaluation of an Hprt-Luciferase Reporter Gene on a Mammalian Artificial Chromosome in Response to Cytotoxicity. | Endo, T., Noda, N., Kuromi, Y., Kokura, K., Kazuki, Y., Oshimura, M., Ohbayashi, T. | Yonago Acta Med. 59 (2): 174-182 (2016). | 47470 | 27493490 |
Atg20- and Atg24-family proteins promote organelle autophagy in fission yeast. | Zhao, D., Liu, X.M., Yu, Z.Q., Sun, L.L., Xiong, X., Dong, M.Q., Du, L.L. | J. Cell Sci. 129 (22): 4289-4304 (2016). | 47468 | 27737912 |
Hyaluronan Production Regulates Metabolic and Cancer Stem-like Properties of Breast Cancer Cells via Hexosamine Biosynthetic Pathway-coupled HIF-1 Signaling. | Chanmee, T., Ontong, P., Izumikawa, T., Higashide, M., Mochizuki, N., Chokchaitaweesuk, C., Khansai, M., Nakajima, K., Kakizaki, I., Kongtawelert, P., Taniguchi, N., Itano, N. | J. Biol. Chem. 291 (46): 24105-24120 (2016). | 47460 | 27758869 |
Augmented Growth Hormone Secretion and Stat3 Phosphorylation in an Aryl Hydrocarbon Receptor Interacting Protein (AIP)-Disrupted Somatotroph Cell Line. | Fukuda, T., Tanaka, T., Hamaguchi, Y., Kawanami, T., Nomiyama, T., Yanase, T. | PLoS One 11 (10): e0164131 (2016). | 47321 | 27706259 |
Effect of chitosan on reactor performance and population of specific methanogens in a modified CSTR treating raw POME. | Khemkhao, M., Techkarnjanaruk, S., Phalakornkule, C. | Biomass and Bioenergy 86: 11-20 (2016). | 47291 | |
B Cell-Based Seamless Engineering of Antibody Fc Domains. | Hashimoto, K., Kurosawa, K., Murayama, A., Seo, H., Ohta, K. | PLoS One 11 (12): e0167232 (2016). | 47287 | 27907066 |
ASPL-TFE3 Oncoprotein Regulates Cell Cycle Progression and Induces Cellular Senescence by Up-Regulating p21. | Ishigro, N., Yoshida, H. | Neoplasia 18 (10): 626-635 (2016). | 47268 | 27673450 |
CCT2 Mutations Evoke Leber Congenital Amaurosis due to Chaperone Complex Instability. | Minegishi, Y., Sheng, X., Yoshitake, K., Sergeev, Y., Iejima, D., Shibagaki, Y., Monma, N., Ikeo, K., Furuno, M., Zhuang, W., Liu, Y., Rong, W., Hattori, S., Iwata, T. | Sci. Rep. 6: 33742 (2016). | 47267 | 27645772 |
Mitochondrial cereblon functions as a Lon-type protease. | Kataoka, K., Nakamura, C., Asahi, T., Sawamura, N. | Sci. Rep. 6: 29986 (2016). | 47266 | 27417535 |
Draft genome sequence of Syntrophomonas wolfei subsp. methylbutyratica strain 4J5T (JCM 14075), a mesophilic butyrate- and 2-methylbutyrate-degrading syntroph. | Narihiro, T., Nobu, M.K., Tamaki, H., Kamagata, Y., Liu, W.T. | Genome Announc. 4 (2): e00047-16 (2016). | 47265 | 26941138 |
Comparative genomics of syntrophic branched-chain fatty acid degrading bacteria. | Narihiro, T., Nobu, M.K., Tamaki, H., Kamagata, Y., Sekiguchi, Y., Liu, W.T. | Microbes environ. 31 (3): 288-292 (2016). | 47264 | 27431485 |
Microscopy-based Saccharomyces cerevisiae complementation model reveals functional conservation and redundancy of N-terminal acetyltransferases. | Osberg, C., Aksnes, H., Ninzima, S., Marie, M., Arnesen, T. | Sci. Rep. 6: 31627 (2016). | 47224 | 27555049 |
Structure and Function of the RING Domains of RNF20 and RNF40, Dimeric E3 Ligases that Monoubiquitylate Histone H2B. | Foglizzo, M., Middleton, A.J., Day, C.L. | J. Mol. Biol. 428 (20): 4073-4086 (2016). | 47223 | 27569044 |
Identification of Novel Mutations in the LRR-Cap Domain of C21orf2 in Japanese Patients With Retinitis Pigmentosa and Cone-Rod Dystrophy. | Suga, A., Mizota, A., Kato, M., Kuniyoshi, K., Yoshitake, K., Sultan, W., Yamazaki, M., Shimomura, Y., Ikeo, K., Tsunoda, K., Iwata, T. | Invest. Ophthalmol. Vis. Sci. 57 (10): 4255-4263 (2016). | 47222 | 27548899 |
Sequence Diversity, Intersubgroup Relationships, and Origins of the Mouse Leukemia Gammaretroviruses of Laboratory and Wild Mice. | Bamunusinghe, D., Naghashfar, Z., Buckler-White, A., Plishka, R., Baliji, S., Liu, Q., Kassner, J., Oler, A.J., Hartley, J., Kozak, C.A. | J. Virol. 90 (8): 4186-4198 (2016). | 46504 | 26865715 |
Influenza virus susceptibility of wild-derived CAST/EiJ mice results from two amino acid changes in the MX1 restriction factor. | Nurnberger, C., Zimmermann, V., Gerhardt, M., Staeheli, P. | J Virol. 2016 Nov 14;90(23):10682-10692 (2016). | 46503 | 27654285 |
Merlin/NF2-Lin28B-let-7 Is a Tumor-Suppressive Pathway that Is Cell-Density Dependent and Hippo Independent. | Hikasa, H., Sekido, Y., Suzuki, A. | Cell Rep. 14 (12): 2950-2961 (2016). | 45806 | 26997273 |
Conformational plasticity of JRAB/MICAL-L2 provides ‘law and order’ in collective cell migration. | Sakane, A., Yoshizawa, S., Nishimura, M., Tsuchiya, Y., Matsushita, N., Miyake, K., Horikawa, K., Imoto, I., Mizuguchi, C., Saito, H., Ueno, T., Matsushita, S., Haga, H., Deguchi, S., Mizuguchi, K., Yokota, H., Sasaki, T. | Mol. Biol. Cell 27(20): 3095-3108 (2016). | 45803 | 27582384 |
SGO1 is involved in the DNA damage response in MYCN-amplified neuroblastoma cells. | Murakami-Tonami, Y., Ikeda, H., Yamagishi, R., Inayoshi, M., Inagaki, S., Kishida, S., Komata, Y., Koster, J., Takeuchi, I., Kondo, Y., Maeda, T., Sekido, Y., Murakami, H., Kadomatsu, K. | Sci. Rep. 6: 31615 (2016). | 45802 | 27539729 |
Antagonizing effect of CLPABP on the function of HuR as a regulator of ARE-containing leptin mRNA stability and the effect of its depletion on obesity in old male mouse. | Nishino, T., Matsunaga, R., Jikihara, H., Uchida, M., Maeda, A., Qi, G., Abe, T., Kiyonari, H., Tashiro, S., Inagaki-Ohara, K., Shimamoto, F., Konishi, H. | Biochim. Biophys. Acta 1861 (11): 1816-1827 (2016). | 45608 | 27616329 |
Ciliary Entry of the Hedgehog Transcriptional Activator Gli2 Is Mediated by the Nuclear Import Machinery but Differs from Nuclear Transport in Being Imp-alpha/beta1-Independent. | Torrado, B., Grana, M., Badano, J.L., Irigoin, F. | PLoS One 11 (8): e0162033 (2016). | 45607 | 27579771 |
Discovery of allosteric modulators for GABAA receptors by ligand-directed chemistry. | Yamaura, K., Kiyonaka, S., Numata, T., Inoue, R., Hamachi, I. | Nat. Chem. Biol. 12 (10): 822-830 (2016). | 41314 | 27526031 |
MEF2D-BCL9 Fusion Gene Is Associated With High-Risk Acute B-Cell Precursor Lymphoblastic Leukemia in Adolescents. | Suzuki, K., Okuno, Y., Kawashima, N., Muramatsu, H., Okuno, T., Wang, X., Kataoka, S., Sekiya, Y., Hamada, M., Murakami, N., Kojima, D., Narita, K., Narita, A., Sakaguchi, H., Sakaguchi, K., Yoshida, N., Nishio, N., Hama, A., Takahashi, Y., Kudo, K., Kato, K., Kojima, S. | J. Clin. Oncol. 34 (28): 3451-3459 (2016). | 41313 | 27507882 |
Nonrandom Germline Transmission of Mouse Spermatogonial Stem Cells. | Kanatsu-Shinohara, M., Naoki, H., Shinohara, T. | Dev. Cell 38 (3): 248-261 (2016). | 41312 | 27505415 |
A putative adenosine kinase family protein possesses adenosine diphosphatase activity. | Tomoike, F., Tsunetou, A., Kim, K., Nakagawa, N., Kuramitsu, S., Masui, R. | Biosci. Biotechnol. Biochem. 80 (11): 2138-2143 (2016). | 41311 | 27484886 |
A Putative Association of a Single Nucleotide Polymorphism in GPR126 with Aggressive Periodontitis in a Japanese Population. | Kitagaki, J., Miyauchi, S., Asano, Y., Imai, A., Kawai, S., Michikami, I., Yamashita ,M., Yamada, S., Kitamura, M., Murakami, S. | PLoS One 11 (8): e0160765 (2016). | 41305 | 27509131 |
53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration. | Meitinger, F., Anzola, J.V., Kaulich, M., Richardson, A., Stender, J.D., Benner, C., Glass, C.K., Dowdy, S.F., Desai, A., Shiau, A.K., Oegema, K. | J. Cell Biol. 214 (2): 155-166 (2016). | 39660 | 27432897 |
Microinjection-based generation of mutant mice with a double mutation and a 0.5 Mb deletion in their genome by the CRISPR/Cas9 system. | Hara, S., Kato, T., Goto, Y., Kubota, S., Tamano, M., Terao, M., Takada, S. | J. Reprod. Dev. 62 (5): 531-536 (2016). | 39659 | 27396308 |
High-speed atomic force microscopy reveals strongly polarized movement of clostridial collagenase along collagen fibrils. | Watanabe-Nakayama, T., Itami, M., Kodera, N., Ando, T., Konno, H. | Sci. Rep. 6: 28975 (2016). | 39658 | 27373458 |
Positive Feedback Loop of OCT4 and c-JUN Expedites Cancer Stemness in Liver Cancer. | Kuo, K.K., Lee, K.T., Chen, K.K., Yang, Y.H., Lin, Y.C., Tsai, M.H., Wuputra, K., Lee, Y.L., Ku, C.C., Miyoshi, H., Nakamura, Y., Saito, S., Wu, C.C., Chai, C.Y., Eckner, R., Steve Lin, C.L., Wang, S.S., Wu, D.C., Lin, C.S., Yokoyama, K.K. | Stem Cells 34 (11): 2613-2624 (2016). | 39657 | 27341307 |
Downregulation of CREB Promotes Cell Proliferation by Mediating G1/S Phase Transition in Hodgkin Lymphoma. | Lu, F., Zheng, Y., Donkor, P.O., Zou, P., Mu, P. | Oncol. Res. 24 (3): 171-179 (2016). | 39656 | 27458098 |
In vitro synthesis of polyhydroxyalkanoates using thermostable acetyl-CoA synthetase, CoA transferase, and PHA synthase from thermotorelant bacteria. | Tajima, K., Han, X., Hashimoto, Y., Satoh, Y., Satoh, T., Taguchi, S. | J. Biosci. Bioeng. pii: S1389-1723 (16) 30121-30129 (2016). | 39655 | 27342638 |
Structural basis for amino acid export by DMT superfamily transporter YddG. | Tsuchiya, H., Doki, S., Takemoto, M., Ikuta, T., Higuchi, T., Fukui, K., Usuda, Y., Tabuchi, E., Nagatoishi, S., Tsumoto, K., Nishizawa, T., Ito, K., Dohmae, N., Ishitani, R., Nureki, O. | Nature 534 (7607): 417-420 (2016). | 39654 | 27281193 |
Proteomics analysis with a nano Random Forest approach reveals novel functional interactions regulated by SMC complexes on mitotic chromosomes. | Ohta, S., Montano-Gutierrez, L.F., Alves, F.L., Ogawa, H., Toramoto, I., Sato, N., Morrison, C.G., Takeda, S., Hudson, D.F., Rappsilber, J., Earnshaw, W.C. | Mol. Cell. Proteomics. pii: mcp.M116.057885 (2016).user report | 36994 | 27231315 |
Novel method for the high-throughput production of phosphorylation site-specific monoclonal antibodies. | Kurosawa, N., Wakata, Y., Inobe, T., Kitamura, H., Yoshioka, M., Matsuzawa, S., Kishi, Y., Isobe, M. | Sci. Rep. 6: 25174 (2016). | 36825 | 27125496 |
A genomic region transcribed into a long noncoding RNA interacts with the Prss42/Tessp-2 promoter in spermatocytes during mouse spermatogenesis, and its flanking sequences can function as enhancers. | Yoneda, R., Satoh, Y., Yoshida, I., Kawamura, S., Kotani, T., Kimura, A.P. | Mol. Reprod. Dev. 83 (6): 541-557 (2016). | 36824 | 27111572 |
Plasmid DNA delivery by arginine-rich cell-penetrating peptides containing unnatural amino acids. | Kato, T., Yamashita, H., Misawa, T., Nishida, K., Kurihara, M., Tanaka, M., Demizu, Y., Oba, M. | Bioorg. Med. Chem. pii: S0968-0896 (16) 30275-9 (2016). | 36823 | 27132868 |
Generation of Large Numbers of Antigen-Expressing Human Dendritic Cells Using CD14-ML Technology. | Imamura, Y., Haruta, M., Tomita, Y., Matsumura, K., Ikeda, T., Yuno, A., Hirayama, M., Nakayama, H., Mizuta, H., Nishimura, Y., Senju, S. | PLoS One. 2016 Apr 6;11(4):e0152384 (2016). | 36822 | 27050553 |
Eupatilin induces Sestrin2-dependent autophagy to prevent oxidative stress. | Jegal, K.H., Ko, H.L., Park, S.M., Byun, S.H., Kang, K.W., Cho, I.J., Kim, S.C. | Apoptosis 21 (5): 642-656 (2016). | 36732 | 27015669 |
Arg-Gly-Asp (RGD)-Modified E1A/E1B Double Mutant Adenovirus Enhances Antitumor Activity in Prostate Cancer Cells In Vitro and in Mice. | Shen, Y.H., Yang, F., Wang, H., Cai, Z.J., Xu, Y.P., Zhao, A., Su, Y., Zhang, G., Zhu, S.X. | PLoS One. 11 (1): e0147173 (2016). | 36054 | 26799485 |
LSD1 Mediates Neuronal Differentiation of Human Fetal Neural Stem Cells by Controlling The Expression of a Novel Target Gene, HEYL. | Hirano, K., Namihira, M. | Stem Cells 34 (7): 1872-1882 (2016). | 36050 | 27018646 |
A key role of PGC-1alpha transcriptional coactivator in production of VEGF by a novel angiogenic agent COA-Cl in cultured human fibroblasts. | Igarashi, J., Okamoto, R., Yamashita, T., Hashimoto, T., Karita, S., Nakai, K., Kubota, Y., Takata, M., Yamaguchi, F., Tokuda, M., Sakakibara, N., Tsukamoto, I., Konishi, R., Hirano, K. | Physiol. Rep. 4 (6). pii: e12742 (2016). | 36049 | 27033444 |
Dysregulation of Nutrient Sensing and CLEARance in Presenilin Deficiency. | Reddy, K., Cusack, C.L., Nnah, I.C., Khayati, K., Saqcena, C., Huynh, T.B., Noggle, S.A., Ballabio A., Dobrowolski, R. | Cell Rep. 14 (9): 2166-2179 (2016). | 36033 | 26923592 |
Inhibition of PA endonuclease activity of influenza virus RNA polymerase by Kampo medicines. | Shirayama, R., Shoji, M., Sriwilaijaroen, N., Hiramatsu, H., Suzuki, Y., Kuzuhara, T. | Drug Discov. Ther. 10 (2): 109-113 (2016). | 36032 | 26902927 |
beta-carotene reverses multidrug resistant cancer cells by selectively modulating human P-glycoprotein function. | Teng, Y.N., Sheu, M.J., Hsieha, Y.W., Wang, R.Y., Chiang, Y.C., Hung, C.C. | Phytomedicine 23 (3): 316-323, 2016. | 36029 | 26969385 |
Receptor tyrosine kinase-like orphan receptor 1, a target of NKX2-1/TTF-1 lineage-survival oncogene, inhibits apoptosis signal-regulating kinase 1-mediated pro-apoptotic signaling in lung adenocarcinoma. | Ida, L., Yamaguchi, T., Yanagisawa, K., Kajino, T., Shimada, Y., Suzuki, M., Takahashi, T. | Cancer Sci. 107 (2): 155-161 (2016). | 36028 | 26661061 |
PAX6 Isoforms, along with Reprogramming Factors, Differentially Regulate the Induction of Cornea-specific Genes. | Sasamoto, Y., Hayashi, R., Park, S.J., Saito-Adachi, M., Suzuki, Y., Kawasaki, S., Quantock, A.J., Nakai, K., Tsujikawa, M., Nishida, K. | Sci. Rep. 6: 20807, 2016. | 35968 | 26899008 |
A Comprehensive Genomic Analysis Reveals the Genetic Landscape of Mitochondrial Respiratory Chain Complex Deficiencies. | Kohda, M., Tokuzawa, Y., Kishita, Y., Nyuzuki, H., Moriyama, Y., Mizuno, Y., Hirata, T., Yatsuka, Y., Yamashita-Sugahara, Y., Nakachi, Y., Kato, H.,., Okuda, A., Tamaru, S., Borna, N.N., Banshoya, K., Aigaki, T., Sato-Miyata, Y., Ohnuma, K., Suzuki, T., Nagao, A., Maehata, H., Matsuda, F., Higasa, K., Nagasaki, M., Yasuda, J., Yamamoto, M., Fushimi, T., Shimura, M., Kaiho-Ichimoto, K., Harashima, H., Yamazaki, T., Mori, M., Murayama, K., Ohtake, A., Okazaki, Y. | PLoS Genet. 12 (1): e1005679 (2016). | 35951 | 26741492 |
MicroRNA-31 is a positive modulator of endothelial-mesenchymal transition and associated secretory phenotype induced by TGF-beta. | Katsura, A., Suzuki, H.I., Ueno, T., Mihira, H., Yamazaki, T., Yasuda, T., Watabe, T., Mano, H., Yamada, Y., Miyazono, K. | Genes Cells 21 (1): 99-116 | 35947 | 26663584 |
Reversible interconversion and maintenance of mammary epithelial cell characteristics by the ligand-regulated EGFR system. | Fukuda, S., Nishida-Fukuda, H., Nanba, D., Nakashiro, K., Nakayama, H., Kubota, H., Higashiyama, S. | Sci. Rep. 6: 20209 (2016). | 35936 | 26831618 |
Cytokine-dependent activation of JAK-STAT pathway in Saccharomyces cerevisiae. | Yoshimoto, N., Ikeda, Y., Tatematsu, K., Iijima, M., Nakai, T., Okajima, T., Tanizawa, K., Kuroda, S. | Biotechnol. Bioeng. 113 (8): 1796-1804 (2016). | 35935 | 26853220 |
Genomic Sequencing Identifies ELF3 as a Driver of Ampullary Carcinoma. | Yachida, S., Wood, L.D., Suzuki, M., Takai, E., Totoki, Y., Kato, M., Luchini, C., Arai, Y., Nakamura, H., Hama, N., Elzawahry, A., Hosoda, F., Shirota, T., Morimoto, N., Hori, K., Funazaki, J., Tanaka, H., Morizane, C., Okusaka, T., Nara, S., Shimada, K., Hiraoka, N., Taniguchi, H., Higuchi, R., Oshima, M., Okano, K., Hirono, S., Mizuma, M., Arihiro, K., Yamamoto, M., Unno, M., Yamaue, H., Weiss, M.J., Wolfgang, CL., Furukawa, T., Nakagama, H., Vogelstein, B., Kiyono, T., Hruban, R.H., Shibata, T. | Cancer Cell pii: S1535-6108 (15) 00476-6 (2016). | 35776 | 26806338 |
Identification of DPY19L3 as the C-mannosyltransferase of R-spondin1 in human cells. | Niwa, Y., Suzuki, T., Dohmae, N., Simizu, S. | Mol. Biol. Cell 27 (5): 744-756 (2016). | 35760 | 26764097 |
Transcription Factors and Medium Suitable for Initiating the Differentiation of Human Induced Pluripotent Stem Cells to the Hepatocyte Lineage. | Tomizawa, M., Shinozaki, F., Motoyoshi, Y., Sugiyama, T., Yamamoto, S., Ishige, N. | J. Cell. Biochem. 117 (9): 2001-2009 (2016). | 35759 | 26773721 |
ssODN-mediated knock-in with CRISPR-Cas for large genomic regions in zygotes. | Yoshimi, K., Kunihiro, Y., Kaneko, T., Nagahora, H., Voigt, B., Mashimo, T. | Nat. Commun. 7: 10431 (2016). | 35757 | 26786405 |
Maternal IL-6 can cause T cell-mediated juvenile alopecia by non-scarring follicular dystrophy in mice. | Smith, S.E., Maus, R.L., Davis, T.R., Sundberg, J.P., Gil, D., Schrum, A.G. | Exp. Dermatol. 25 (3): 223-228 (2016). | 35678 | 26660334 |
An in vitro system to characterize prostate cancer progression identified signaling required for self-renewal. | Salah, M., Nishimoto, Y., Kohno, S., Kondoh, A., Kitajima, S., Muranaka, H., Nishiuchi, T., Ibrahim, A., Yoshida, A., Takahashi, C. | Mol. Carcinog. 55 (12): 1974-1989 (2016). | 35466 | 26621780 |
Ligand-inducible dimeric antibody for selecting antibodies against a membrane protein based on mammalian cell proliferation. | Miura, T., Nagamune, T., Kawahara, M. | Biotechnol. Bioeng. 113 (5): 1113-1123 (2016). | 34900 | 26479395 |
2015
Title | Author | Journal | NBRP RRC ID | PubMed PMID |
---|---|---|---|---|
3beta-hydroxysterol delta24-reductase on the surface of hepatitis C virus-related hepatocellular carcinoma cells can be a target for molecular targeting therapy. | Saito, M., Takano, T., Nishimura, T., Kohara, M., Tsukiyama-Kohara, K. | PLoS One 10 (4): e0124197 (2015). | 57436 | 25875901 |
Phospholipid Flippase ATP10A Translocates Phosphatidylcholine and Is Involved in Plasma Membrane Dynamics. | Naito, T., Takatsu, H., Miyano, R., Takada, N., Nakayama, K., Shin, H.W. | J. Biol. Chem. 290 (24): 15004-15017 (2015). | 54532 | 25947375 |
High-level production of (5S)-hydroxyhexane-2-one by two thermostable oxidoreductases in a whole-cell catalytic approach | Diederichs, S., Linn, K., Luckgen, J., Klement, T., Grosch, J.-H., Honda, K., Ohtake, H., Buchs, J. | J. Mol. Catalysis B: Enzymatic 121: 37?44 (2015) | 53898 | |
A CAR-responsive enhancer element locating approximately 31 kb upstream in the 5′-flanking region of rat cytochrome P450 (CYP) 3A1 gene. | Gamou, T., Habano, W., Terashima, J., Ozawa, S. | Drug Metab. Pharmacokinet. 30 (2): 188-97 (2015). | 53896 | 25989892 |
Reconstitution of mitotic chromatids with a minimum set of purified factors. | Shintomi, K., Takahashi, T.S., Hirano, T. | Nat. Cell Biol. 17 (8): 1014-1023 (2015). | 53895 | 26075356 |
Epigenetic Heterogeneity in HIV-1 Latency Establishment. | Matsuda, Y., Kobayashi-Ishihara, M., Fujikawa, D., Ishida, T., Watanabe, T., Yamagishi, M. | Sci. Rep. 5: 7701 (2015). | 53152 | 25572573 |
Is D-aspartate produced by glutamic-oxaloacetic transaminase-1 like 1 (Got1l1): a putative aspartate racemase? | Tanaka-Hayashi, A., Hayashi, S., Inoue, R., Ito, T., Konno, K., Yoshida, T., Watanabe, M., Yoshimura, T., Mori, H. | Amino Acids 47 (1): 79-86 (2015). | 48756 | 25287256 |
The CDKN1B-RB1-E2F1 pathway protects mouse spermatogonial stem cells from genomic damage. | Tanaka, T., Kanatsu-Shinohara, M., Shinohara, T. | J. Reprod. Dev. 61 (4): 305-316 (2015). | 48550 | 25959802 |
The zinc finger transcription factor RP58 negatively regulates Rnd2 for the control of neuronal migration during cerebral cortical development. | Heng, J.I., Qu, Z., Ohtaka-Maruyama, C., Okado, H., Kasai, M., Castro, D., Guillemot, F., Tan, S.S. | Cereb. Cortex 25 (3): 806-816 (2015). | 48548 | 24084125 |
Bulk Segregant Analysis Reveals the Genetic Basis of a Natural Trait Variation in Fission Yeast. | Hu, W., Suo, F., Du, L.L. | Genome Biol. Evol. 7 (12): 3496-3510 (2015). | 47475 | 26615217 |
CRISPR/Cas9-mediated reporter knock-in in mouse haploid embryonic stem cells. | Kimura, Y., Oda, M., Nakatani, T., Sekita, Y., Monfort, A., Wutz, A., Mochizuki, H., Nakano, T. | Sci. Rep. 5: 10710 (2015) | 41306 | 26039937 |
Stella preserves maternal chromosome integrity by inhibiting 5hmC-induced gammaH2AX accumulation. | Nakatani, T., Yamagata, K., Kimura, T., Oda, M., Nakashima, H., Hori, M., Sekita, Y., Arakawa, T., Nakamura, T., Nakano, T. | EMBO Rep. 16 (5): 582-9 (2015). | 39501 | 25694116 |
Nucleolar protein PES1 is a marker of neuroblastoma outcome and is associated with neuroblastoma differentiation. | Nakaguro, M., Kiyonari, S., Kishida, S., Cao, D., Murakami-Tonami, Y., Ichikawa, H., Takeuchi, I., Nakamura, S., Kadomatsu, K. | Cancer Sci. 106 (3): 237-243 (2015). | 36897 | 25557119 |
Synthetic lateral inhibition governs cell-type bifurcation with robust ratios. | Matsuda, M., Koga, M., Woltjen, K., Nishida, E., Ebisuya, M. | Nat. Commun. 6: 6195 (2015). | 36055 | 25652697 |
Development of a new real-time PCR system for simultaneous detection of bacteria and fungi in pathological samples. | Fukumoto, H., Sato, Y., Hasegawa, H., Saeki, H., Katano, H. | Int. J. Clin. Exp. Pathol. 8 (11): 15479-15488 (2015). | 35779 | 26823918 |
Molecular mechanism by which acyclic retinoid induces nuclear localization of transglutaminase 2 in human hepatocellular carcinoma cells. | Shrestha, R., Tatsukawa, H., Shrestha, R., Ishibashi, N., Matsuura, T., Kagechika, H., Kose, S., Hitomi, K., Imamoto, N., Kojima, S. | Cell Death Dis. 6: e2002 (2015). | 35778 | 26633708 |
The significance of G-CSF expression and myeloid-derived suppressor cells in the chemoresistance of uterine cervical cancer. | Kawano, M., Mabuchi, S., Matsumoto, Y., Sasano, T., Takahashi, R., Kuroda, H., Kozasa, K., Hashimoto, K., Isobe, A., Sawada, K., Hamasaki, T., Morii, E., Kimura, T. | Sci. Rep. 5: 18217 (2015). | 35671 | 26666576 |
TSC-22 up-regulates collagen 3a1 gene expression in the rat heart. | Kelloniemi, A., Aro, J., Napankangas, J., Koivisto, E., Mustonen, E., Ruskoaho, H., Rysa, J. | BMC Cardiovasc. Disord. 15 (1): 122 (2015). | 34894 | 26464165 |
Podoplanin-expressing cancer-associated fibroblasts lead and enhance the local invasion of cancer cells in lung adenocarcinoma. | Neri, S., Ishii, G., Hashimoto, H., Kuwata, T., Nagai, K., Date, H., Ochiai, A. | Int. J. Cancer. 137 (4): 784-796 (2015). | 34846 | 25648219 |
Use of a Human Artificial Chromosome for Delivering Trophic Factors in a Rodent Model of Amyotrophic Lateral Sclerosis. | Watanabe, Y., Kazuki, Y., Kazuki, K., Ebiki, M., Nakanishi, M., Nakamura, K., Yoshida Yamakawa, M., Hosokawa, H., Ohbayashi, T., Oshimura, M., Nakashima, K. | Mol. Ther. Nucleic Acids. 4: e253 (2015). | 34813 | 26440597 |
In vitro dihydrouridine formation by tRNA dihydrouridine synthase from Thermus thermophilus, an extreme-thermophilic eubacterium. | Kusuba, H., Yoshida, T., Iwasaki, E., Awai, T., Kazayama, A., Hirata, A., Tomikawa, C., Yamagami, R., Hori, H. | J. Biochem. 158 (6): 513-521 (2015). | 34797 | 26112661 |
Histone H3 lysine 36 tri-methylation is established over the Xist promoter by antisense Tsix transcription and contributes to repressing Xist expression. | Ohhata, T., Matsumoto, M., Leeb, M., Shibata, S., Sakai, S., Kitagawa, K., Niida, H., Kitagawa, M., Wutz, A. | Mol. Cell. Biol. 35 (22): 3909-3920 (2015). | 34791 | 26370508 |
New type of encephalomyelitis responsive to trimethoprim/sulfamethoxazole treatment in Japan. | Sakiyama, Y., Kanda, N., Higuchi, Y., Yoshimura, M., Wakaguri, H., Takata, Y., Watanabe, O., Yuan, J., Tashiro, Y., Saigo, R., Nozuma, S., Yoshimura, A., Arishima, S., Ikeda, K., Shinohara, K., Arata, H., Michizono, K., Higashi, K., Hashiguchi, A., Okamoto, Y., Hirano, R., Shiraishi, T., Matsuura, E., Okubo, R., Higuchi, I., Goto, M., Hirano, H., Sano, A., Iwasaki, T., Matsuda, F., Izumo, S., Takashima, H. | Neurol. Neuroimmunol. Neuroinflamm. 2 (5): e143 (2015). | 34739 | 26309903 |
NOTCH2 signaling confers immature morphology and aggressiveness in human hepatocellular carcinoma cells. | Hayashi, Y., Osanai, M., Lee, G.H. | Oncol. Rep. 34, 1650-1658 (2015). | 34560 | 26252838 |
Actin Migration Driven by Directional Assembly and Disassembly of Membrane-Anchored Actin Filaments. | Katsuno, H., Toriyama, M., Hosokawa, Y., Mizuno, K., Ikeda, K., Sakumura, Y., Inagaki, N. | Cell Rep. 12 (4): 648-660 (2015). | 34526 | 26190109 |
Cereblon is recruited to aggresome and shows cytoprotective effect against ubiquitin-proteasome system dysfunction. | Sawamura, N., Wakabayashi, S., Matsumoto, K., Yamada, H., Asahi, T. | Biochem Biophys Res Commun. 2015 Jul 15. pii: S0006-291X(15)30298-9 | 34525 | 26188093 |
Structural basis for dynamic mechanism of nitrate/nitrite antiport by NarK. | Fukuda, M., Takeda, H., Kato, H.E., Doki, S., Ito, K., Maturana, A.D., Ishitani, R., Nureki, O. | Nat. Commun. 6: 7097 (2015). | 34495 | 25959928 |
A GSDMB enhancer-driven HSV thymidine kinase-expressing vector for controlling occult peritoneal dissemination of gastric cancer cells. | Saeki, N., Komatsuzaki, R., Chiwaki, F., Yanagihara, K., Sasaki, H. | BMC Cancer 15: 439 (2015). | 33974 | 26016667 |
Transcriptional upregulation of HNF-1β by NF-κB in ovarian clear cell carcinoma modulates susceptibility to apoptosis through alteration in bcl-2 expression. | Suzuki, E., Kajita, S., Takahashi, H., Matsumoto, T., Tsuruta, T., Saegusa, M. | Lab. Invest. 95 (8): 962-972 (2015). | 33973 | 26030369 |
Functional role of the C-terminal tail of the archaeal ribosomal stalk in recruitment of two elongation factors to the sarcin/ricin loop of 23S rRNA. | Imai, H., Miyoshi, T., Murakami, R., Ito, K., Ishino, Y., Uchiumi, T. | Genes Cells 20 (7): 613-624 (2015). | 33972 | 26033302 |
A practical fluorogenic substrate for high-throughput screening of glutathione S-transferase inhibitors. | Fujikawa, Y., Morisaki, F., Ogura, A., Morohashi, K., Enya, S., Niwa, R., Goto, S., Kojima, H., Okabe, T., Nagano, T., Inoue, H. | Chem. Commun. (Camb). 51 (57): 11459-11462 (2015). | 33971 | 26090533 |
Crystal Structure and Functional Analyses of the Lectin Domain of Glucosidase II: Insights into Oligomannose Recognition. | Olson, L.J., Orsi, R., Peterson, F.C., Parodi, A.J., Kim, J.P., D’Alessio, C., Dahms, N.M. | Biochemistry 54 (26): 4097-4111 (2015). | 33947 | 26062005 |
Plasmid DNA delivery using fluorescein-labeled arginine-rich peptides. | Oba, M., Demizu, Y., Yamashita, H., Kurihara, M., Tanaka, M. | Bioorg. Med. Chem. 23 (15): 4911-4918 (2015). | 33725 | 26048025 |
Construction of CoA-dependent 1-butanol synthetic pathway functions under aerobic conditions in Escherichia coli. | Kataoka, N., Vangnai, A.S., Pongtharangkul, T., Tajima, T., Yakushi, T., Matsushita, K., Kato, J. | J. Biotechnol. 204: 25-32 (2015). | 33708 | 25865277 |
Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects. | Hashizume, O., Ohnishi, S., Mito, T., Shimizu, A., Iashikawa, K., Nakada, K., Soda, M., Mano, H., Togayachi, S., Miyoshi, H., Okita, K., Hayashi, J. | Sci. Rep. 5: 10434 (2015). | 33706 | 26000717 |
Crystal structure and substrate-binding mode of GH63 mannosylglycerate hydrolase from Thermus thermophilus HB8. | Miyazaki, T., Ichikawa, M., Iino, H., Nishikawa, A., Tonozuka, T. | J. Struct. Biol. 190 (1): 21-30 (2015). | 33603 | 25712767 |
Activation of NF-κB by Human Papillomavirus 16 E1 Limits E1-Dependent Viral Replication through Degradation of E1. | Nakahara, T., Tanaka, K., Ohno, S., Egawa, N., Yugawa, T., Kiyono, T. | J. Virol. 89 (9): 5040-5059 (2015). | 33214 | 25717108 |
Inflammation and hypoxia linked to renal injury by CCAAT/enhancer-binding protein delta. | Yamaguchi, J., Tanaka, T., Eto, N., Nangaku, M. | Kidney Int. 88 (2): 262-275 (2015). | 33213 | 25692954 |
A Naturally Occurring Null Variant of the NMDA Type Glutamate Receptor NR3B Subunit Is a Risk Factor of Schizophrenia. | Matsuno, H., Ohi, K., Hashimoto, R., Yamamori, H., Yasuda, Y., Fujimoto, M., Yano-Umeda, S., Saneyoshi, T., Takeda, M., Hayashi, Y. | PLoS One 10 (3): e0116319 (2015). | 33180 | 25768306 |
Eicosapentaenoic acid upregulates VEGF-A through both GPR120 and PPARγ mediated pathways in 3T3-L1 adipocytes. | Hasan, A.U., Ohmori, K., Konishi, K., Igarashi, J., Hashimoto, T., Kamitori, K., Yamaguchi, F., Tsukamoto, I., Uyama, T., Ishihara, Y., Noma, T., Tokuda, M., Kohno, M. | Mol. Cell. Endocrinol. 406:10-18 (2015). | 32799 | 25697344 |
Chromatin remodelling and autocrine TNF alpha are required for optimal interleukin-6 expression in activated human neutrophils. | Zimmermann, M., Aguilera, F.B., Castellucci, M., Rossato, M., Costa, S., Lunardi, C., Ostuni, R., Girolomoni, G., Natoli, G., Bazzoni, F., Tamassia, N., Cassatella, M.A. | Nat. Commun. 6: 6061 (2015). | 32716 | 25616107 |
The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin. | Epting, D., Slanchev, K., Boehlke, C., Hoff, S., Loges, N.T., Yasunaga, T., Indorf, L., Nestel, S., Lienkamp, S.S., Omran, H., Kuehn, E.W., Ronneberger, O., Walz, G., Kramer-Zucker, A. | Development 42 (1): 174-184 (2015). | 32637 | 25516973 |
IL-33 activates eosinophils of visceral adipose tissue both directly and via innate lymphoid cells. | Hashiguchi, M., Kashiwakura, Y., Kojima, H., Kobayashi, A., Kanno, Y., Kobata, T. | Eur J Immunol. 2015 | 32636 | 25504587 |
Paired related homeobox 1 is associated with the invasive properties of glioblastoma cells. | Sugiyama, M., Hasegawa, H., Ito, S., Sugiyama, K., Maeda, M., Aoki, K., Wakabayashi, T., Hamaguchi, M., Natsume, A., Senga, T. | Oncol. Rep. 33 (3): 1123-1130 (2015). | 32635 | 25522823 |
Demethoxycurcumin Modulates Human P-Glycoprotein Function via Uncompetitive Inhibition of ATPase Hydrolysis Activity. | Teng, Y.N., Hsieh, Y.W., Hung, C.C., Lin, H.Y. | J. Agric. Food Chem. 63 (3): 847-855 (2015). | 32575 | 25594233 |
Fission yeast Cactin restricts telomere transcription and elongation by controlling Rap1 levels. | Lorenzi, L.E., Bah, A., Wischnewski, H., Shchepachev, V., Soneson, C., Santagostino, M., Azzalin, C.M.. | EMBO J. 34 (1): 115-129 (2015). | 32213 | 25398909 |
Structural basis for the facilitative diffusion mechanism by SemiSWEET transporter. | Lee, Y., Nishizawa, T., Yamashita, K., Ishitani, R., Nureki, O. | Nat. Commun. 6: 6112 (2015). | 32211 | 25598322 |
Rapid Evaluation of Tyrosine Kinase Activity of Membrane-Integrated Human Epidermal Growth Factor Receptor Using the Yeast G gamma Recruitment System. | Fukuda, N., Honda, S. | ACS Synth. Biol. 4 (4): 421-429 (2015). | 31880 | 25006755 |
Cabozantinib reverses multidrug resistance of human hepatoma HepG2/adr cells by modulating the function of P-glycoprotein. | Xiang, Q.F., Zhang, D.M., Wang, J.N., Zhang, H.W., Zheng, Z.Y., Yu, D.C., Li, Y.J., Xu, J., Chen, Y.J., Shang, C.Z. | Liver Int. 35 (3): 1010-1023 (2015). | 31701 | 24621440 |
YM155 sensitizes triple-negative breast cancer to membrane-bound TRAIL through p38 MAPK- and CHOP-mediated DR5 upregulation. | Pennati, M., Sbarra, S., De Cesare, M., Lopergolo, A., Locatelli, S.L., Campi, E., Daidone, M.G., Carlo-Stella, C., Gianni, A.M., Zaffaroni, N. | Int. J. Cancer 136 (2): 299-309 (2015). | 30914 | 24866585 |
2014
Title | Author | Journal | NBRP RRC ID | PubMed PMID |
---|---|---|---|---|
CBP-93872 inhibits NBS1-mediated ATR activation, abrogating maintenance of the DNA double-strand break-specific G2 checkpoint. | Hirokawa, T., Shiotani, B., Shimada, M., Murata, K., Johmura, Y., Haruta, M., Tahara, H., Takeyama, H., Nakanishi, M. | Cancer Res. 74 (14): 3880-3889 (2014). | 56567 | 24876101 |
A candidate enhancer element responsible for high-level expression of the aggrecan gene in chondrocytes. | Ikeda, Y., Ito, K., Izumi, Y., Shinomura, T. | J. Biochem. 156 (1): 21-28 (2014). | 53897 | 24554731 |
Oxidative stress-induced JNK1 phosphorylation inhibits hedgehog signalling and osteoblast differentiation. | Shiohama, T., Fujii, K., Uchikawa, H., Takatani, T., Mizuochi, H., Kohno, Y. | Cell Biol. Int. Rep. 21 (2); 53-62 (2014). | 50052 | |
Characterization of common marmoset dysgerminoma-like tumor induced by the lentiviral expression of reprogramming factors. | Yamaguchi, S., Marumoto, T., Nii, T., Kawano, H., Liao, J., Nagai, Y., Okada, M., Takahashi, A., Inoue, H., Sasaki, E., Fujii, H., Okano, S., Ebise, H., Sato, T., Suyama, M., Okano, H., Miura, Y., Tani, K. | Cancer Sci. 105 (4): 402-408 (2014). | 48012 | 24521492 |
Application of a phosphite dehydrogenase gene as a novel dominant selection marker for yeasts. | Kanda, K., Ishida, T., Hirota, R., Ono, S., Motomura, K., Ikeda, T., Kitamura, K., Kuroda, A. | J. Biotechnol. 182-183: 68-73 (2014). | 47472 | 24786825 |
Fission yeast Pxd1 promotes proper DNA repair by activating Rad16XPF and inhibiting Dna2. | Zhang, J.M., Liu, X.M., Ding, Y.H., Xiong, L.Y., Ren, J.Y., Zhou, Z.X., Wang, H.T., Zhang, M.J., Yu, Y., Dong, M.Q., Du, L.L. | PLoS Biol. 12 (9): e1001946 (2014). | 47466 | 25203555 |
Phospholipid flippase activities and substrate specificities of human type IV P-type ATPases localized to the plasma membrane. | Takatsu, H., Tanaka, G., Segawa, K., Suzuki, J., Nagata, S., Nakayama, K., Shin, H.W. | J. Biol. Chem. 289 (48): 33543-33556 (2014). | 47459 | 25315773 |
Anti-apoptotic roles for the mutant p53R248Q through suppression of p53-regulated apoptosis-inducing protein 1 in the RA-derived fibroblast-like synoviocyte cell line MH7A. | Igarashi, H., Hirano, H., Yahagi, A., Saika, T., Ishihara, K. | Clin. Immunol. 150 (1): 12-21 (2014). | 36027 | 24316591 |
Uterine cervical cancer displaying tumor-related leukocytosis: a distinct clinical entity with radioresistant feature. | Mabuchi, S., Matsumoto, Y., Kawano, M., Minami, K., Seo, Y., Sasano, T., Takahashi, R., Kuroda, H., Hisamatsu, T., Kakigano, A., Hayashi, M., Sawada, K., Hamasaki, T., Morii, E., Kurachi, H., Matsuura, N., Kimura, T. | J. Natl. Cancer Inst. 106 (7). pii: dju147 (2014). | 35670 | 24948742 |
Survivin-responsive conditionally replicating adenovirus kills rhabdomyosarcoma stem cells more efficiently than their progeny. | Tanoue, K., Wang, Y., Ikeda, M., Mitsui, K., Irie, R., Setoguchi, T., Komiya, S., Natsugoe, S., Kosai, K. | J. Transl. Med. 12: 27 (2014). | 34498 | 24467821 |
Optimized rod length of polyplex micelles for maximizing transfection efficiency and their performance in systemic gene therapy against stroma-rich pancreatic tumors. | Dirisala, A., Osada, K., Chen, Q., Tockary, T.A., Machitani, K., Osawa, S., Liu, X., Ishii, T., Miyata, K., Oba, M., Uchida, S., Itaka, K., Kataoka, K. | Biomaterials, 35 (20): 5359-5368 (2014). | 33958 | 24720877 |
Phenotyping the quality of complex medium components by simple online-monitored shake flask experiments. | Diederichs, S., Korona, A., Staaden, A., Kroutil, W., Honda, K., Ohtake, H., Buchs, J. | Microb. Cell Fact. 13 (1): 149 (2014). | 33604 | 25376163 |
Stimulation of melanogenesis by nordihydroguaiaretic Acid in human melanoma cells. | Takekoshi, S., Nagata, H., Kitatani, K. | Acta Histochem. Cytochem. 47 (5): 203-210 (2014). | 33085 | 25861126 |
Dbx1 triggers crucial molecular programs required for midline crossing by midbrain commissural axons. | Inamata, Y., Shirasaki, R. | Development 141 (6): 1260-1271 (2014). | 32639 | 24553291 |
A conserved noncoding sequence can function as a spermatocyte-specific enhancer and a bidirectional promoter for a ubiquitously expressed gene and a testis-specific long noncoding RNA. | Kurihara, M., Shiraishi, A., Satake, H., Kimura, A.P. | J. Mol. Biol., 426 (17): 3069-3093 (2014). | 32638 | 25020229 |
Geranium dielsianum extract powder (MISKAMISKATM) improves the intestinal environment through alteration of microbiota and microbial metabolites in rats. | Ikeda, T., Tanaka, Y., Yamamoto, K., Morii, H., Kamisako, T., Ogawa, H. | J. Funct. Foods, 11: 12-19 (2014). | 32604 | |
Gentiolactone, a secoiridoid dilactone from Gentiana triflora, inhibits TNF-alpha, iNOS and Cox-2 mRNA expression and blocks NF-kappaB promoter activity in murine macrophages. | Yamada, H., Kikuchi, S., Inui, T., Takahashi, H., Kimura, K. | PLoS One 9 (11): e113834 (2014). | 32576 | 25423092 |
Diverse allosteric and catalytic functions of tetrameric d-lactate dehydrogenases from three Gram-negative bacteria. | Furukawa, N., Miyanaga, A., Togawa, M., Nakajima, M., Taguchi, H. | AMB Express 4: 76 (2014). | 32212 | 25401076 |
Crystallization and preliminary X-ray crystallographic analysis of YfcM: an important factor for EF-P hydroxylation. | Kobayashi, K., Suzuki, T., Dohmae, N., Ishitani, R., Nureki, O. | Acta Crystallogr. F Struct. Biol. Commun. 70 (Pt 9): 1236-1239 (2014). | 31850 | 25195899 |
Aggregation of ALS-linked FUS mutant sequesters RNA binding proteins and impairs RNA granules formation. | Takanashi, K., Yamaguchi, A. | Biochem. Biophys. Res. Commun. 452 (3): 600-607 (2014). | 31849 | 25173930 |
Degradation of amyloid beta by human induced pluripotent stem cell-derived macrophages expressing Neprilysin-2. | Takamatsu, K., Ikeda, T., Haruta, M., Matsumura, K., Ogi, Y., Nakagata, N., Uchino, M., Ando, Y., Nishimura, Y., Senju, S. | Stem Cell Res. 13 (3PA): 442-453 (2014). | 31847 | 25460605 |
ESCRT-0 Protein Hepatocyte Growth Factor-regulated Tyrosine Kinase Substrate (Hrs) Is Targeted to Endosomes Independently of Signal-transducing Adaptor Molecule (STAM) and the Complex Formation with STAM Promotes Its Endosomal Dissociation. | Kojima, K., Amano, Y., Yoshino, K., Tanaka, N., Sugamura, K., Takeshita, T. | J. Biol. Chem. 289 (48): 33296-33310 (2014). | 31846 | 25296754 |
A novel transgenic mouse model carrying human Tribbles related protein 3 (TRB3) gene and its site specific phenotype. | Sakai, Y., Fukamachi, K., Futakuchi, M., Miyoshi, I., Tsuda, H., Suzui, M., Hayashi, H. | Biol. Pharm. Bull., 37 (6): 1068-1074 (2014). | 31844 | 24882419 |
Skp1-Cullin-F-box (SCF)-type ubiquitin ligase FBXW7 negatively regulates spermatogonial stem cell self-renewal. | Kanatsu-Shinohara, M., Onoyama, I., Nakayama, K.I., Shinohara, T. | Proc. Natl. Acad. Sci. U.S.A., 111 (24): 8826-8831 (2014). | 31843 | 24879440 |
In vitro and in vivo effects of xanthorrhizol on human breast cancer MCF-7 cells treated with tamoxifen. | Noomhorm, N., Chang, C.J., Wen, C.S., Wang, J.Y., Chen, J.L., Tseng, L.M., Chen, W.S., Chiu, J.H., Shyr, Y.M. | J. Pharmacol. Sci. 125 (4): 375-385 (2014). | 31694 | 25141924 |
VPS35 dysfunction impairs lysosomal degradation of alpha-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson’s disease. | Miura, E., Hasegawa, T., Konno, M., Suzuki, M., Sugeno, N., Fujikake, N., Geisler, S., Tabuchi, M., Oshima, R., Kikuchi, A., Baba, T., Wada, K., Nagai, Y., Takeda, A., Aoki, M. | Neurobiol. Dis. 71: 1-13 (2014). | 31693 | 25107340 |
Interferon regulatory factor 7 protects against vascular smooth muscle cell proliferation and neointima formation. | Huang, L., Zhang, S.M., Zhang, P., Zhang, X.J., Zhu, L.H., Chen, K., Gao, L., Zhang, Y., Kong, X.J., Tian, S., Zhang, X.D., Li, H. | J. Am. Heart Assoc. 3 (5). pii: e001309 (2014). | 31692 | 25304854 |
Ciona intestinalis NADH dehydrogenase NDX confers stress-resistance and extended lifespan on Drosophila. | Gospodaryov, D.V., Lushchak, O.V., Rovenko, B.M., Perkhulyn, N.V., Gerards, M., Tuomela, T., Jacobs, H.T. | Biochim. Biophys. Acta. -Bioenergetics 1837 (11): 1861-1869 (2014). | 31030 | 25124484 |
Phylobiochemical characterization of class-ib aspartate/prephenate aminotransferases reveals evolution of the plant arogenate phenylalanine pathway. | Dornfeld, C., Weisberg, A.J., K.C.Ritesh, Dudareva, N., Jelesko, J.G., Maeda, H.A. | Plant Cell 26 (7): 3101-3114 (2014). | 31029 | 25070637 |
Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett’s metaplasia. | Wang, D.H., Tiwari, A., Kim, M.E., Clemons, N.J., Regmi, N.L., Hodges, W.A., Berman, D.M., Montgomery, E.A., Watkins, D.N., Zhang, X., Zhang, Q., Jie, C., Spechler, S.J., Souza, R.F. | J. Clin. Invest. 124 (9): 3767-80 (2014). | 31028 | 25083987 |
Identification of a protein glycosylation operon from Campylobacter jejuni JCM 2013 and its heterologous expression in Escherichia coli. | Srichaisupakit, A., Ohashi, T., Fujiyama, K. | J. Biosci. Bioeng. 118 (3): 256-262 (2014). | 30956 | 24650731 |
The role of Pak-interacting exchange facto-beta phosphorylation at serines 340 and 583 by PKC gamma in dopamine release. | Shirafuji, T., Ueyama, T., Yoshino, K., Takahashi, H., Adachi, N., Ago, Y., Koda, K., Nashida, T., Hiramatsu, N., Matsuda, T., Toda, T., Sakai, N., Saito, N. | J. Neurosci., 34 (28): 9268-9280 (2014). | 30930 | 25009260 |
Crystallization and preliminary X-ray diffraction analysis of YidC, a membrane-protein chaperone and insertase from Bacillus halodurans. | Kumazaki, K., Tsukazaki, T., Nishizawa, T., Tanaka, Y., Kato, H.E., Nakada-Nakura, Y., Hirata, K., Mori, Y., Suga, H., Dohmae, N., Ishitani, R., Nureki, O. | Acta Crystallogr. F. Struct. Biol. Commun., 70 (Pt 8): 1056-1060 (2014). | 30929 | 25084381 |
Necdin promotes ubiquitin-dependent degradation of PIAS1 SUMO E3 ligase. | Gur, I., Fujiwara, K., Hasegawa, K., Yoshikawa, K. | PLoS One, 9 (6): e99503 (2014). | 30917 | 24911587 |
Cancer cell specific cytotoxic gene expression mediated by ARF tumor suppressor promoter constructs. | Kurayoshi, K., Ozono, E., Iwanaga, R., Bradford, A.P., Komori, H., Ohtani, K. | Biochem. Biophys. Res. Commun., 450 (1): 240-246 (2014). | 30915 | 24893334 |
Screening to identify commonly used chinese herbs that affect ERBB2 and ESR1 gene expression using the human breast cancer MCF-7 cell line. | Chiu, J.H., Chang, C.J., Wu, J.C., Liu, H.J., Wen, C.S., Hsu, C.H., Chen, J.L., Tseng, L.M., Chen, W.S., Shyr, Y.M. | Evid. Based Complement. Alternat. Med., 965486 (2014). | 30913 | 24987437 |
Human speech- and reading-related genes display partially overlapping expression patterns in the marmoset brain. | Kato, M., Okanoya, K., Koike, T., Sasaki, E., Okano, H., Watanabe, S., Iriki, A. | Brain Lang., 133: 26-38 (2014). | 30904 | 24769279 |
Neurogenin2-d4Venus and Gadd45g-d4Venus transgenic mice: visualizing mitotic and migratory behaviors of cells committed to the neuronal lineage in the developing mammalian brain. | Kawaue, T., Sagou, K., Kiyonari, H., Ota, K., Okamoto, M., Shinoda, T., Kawaguchi, A., Miyata, T. | Dev. Growth Differ., 56 (4): 293-304 (2014). | 30726 | 24712911 |
A combination of Wnt and growth factor signaling induces Arl4c expression to form epithelial tubular structures. | Matsumoto, S., Fujii, S., Sato, A., Ibuka, S., Kagawa, Y., Ishii, M., Kikuchi, A. | EMBO J., 33 (7): 702-718 (2014). | 30725 | 24562386 |
Structural basis of Sec-independent membrane protein insertion by YidC. | Kumazaki, K., Chiba, S., Takemoto, M., Furukawa, A., Nishiyama, K., Sugano, Y., Mori, T., Dohmae, N., Hirata, K., Nakada-Nakura, Y., Maturana, A.D., Tanaka, Y., Mori, H., Sugita, Y., Arisaka, F., Ito, K., Ishitani, R., Tsukazaki, T., Nureki, O. | Nature, 509 (7501): 516-520 (2014). | 30718 | 24739968 |
High-throughput de novo screening of receptor agonists with an automated single-cell analysis and isolation system. | Yoshimoto, N., Tatematsu, K., Iijima, M., Niimi, T., Maturana, A.D., Fujii, I., Kondo, A., Tanizawa, K., Kuroda, S. | Sci Rep., 4: 4242 (2014). | 30717 | 24577528 |
Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkc delta. | Suzuki, S., Franchi, L., He, Y., Munoz-Planillo, R., Mimuro, H., Suzuki, T., Sasakawa, C., Nunez, G. | PLoS Pathog., 10 (2): e1003926 (2014). | 30716 | 24516390 |
Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors. | Ge, Z., Chen, Q., Osada, K., Liu, X., Tockary, T.A., Uchida, S., Dirisala, A., Ishii, T., Nomoto, T., Toh, K., Matsumoto, Y., Oba, M., Kano, M.R., Itaka, K., Kataoka, K. | Biomaterials, 35 (10): 3416-3426 (2014). | 30715 | 24439417 |
Crystallization and preliminary X-ray diffraction studies of a surface mutant of the middle domain of PB2 from human influenza A (H1N1) virus. | Tsurumura, T., Qiu, H., Yoshida, T., Tsumori, Y., Tsuge, H. | Acta. Crystallogr. F Struct. Biol. Commun., 70 (Pt 1): 72-75 (2014). | 30714 | 24419622 |
Proliferation and survival signaling from both Jak2-V617F and Lyn involving GSK3 and mTOR/p70S6K/4EBP1 in PVTL-1 cell line newly established from acute myeloid leukemia transformed from polycythemia vera. | Nagao, T., Kurosu, T., Umezawa, Y., Nogami, A., Oshikawa, G., Tohda, S., Yamamoto, M., Miura, O. | PLoS One, 9 (1): e84746 (2014). | 30713 | 24404189 |
Bovine induced pluripotent stem cells are more resistant to apoptosis than testicular cells in response to mono-(2-ethylhexyl) phthalate. | Lin, Y.C., Kuo, K.K., Wuputra, K., Lin, S.H., Ku, C.C., Yang, Y.H., Wang, S.W., Wang, S.W., Wu, D.C., Wu, C.C., Chai, C.Y., Lin, C.L., Lin, C.S., Kajitani, M., Miyoshi, H., Nakamura, Y., Hashimoto, S., Matsushima, K., Jin, C., Huang, S.K., Saito, S., Yokoyama, K.K. | Int. J. Mol. Sci., 15 (3): 5011-5031 (2014). | 30711 | 24658443 |
The adaptor TRAF5 limits the differentiation of inflammatory CD4(+) T cells by antagonizing signaling via the receptor for IL-6. | Nagashima, H., Okuyama, Y., Asao, A., Kawabe, T., Yamaki, S., Nakano, H., Croft, M., Ishii, N., So, T. | Nat. Immunol., 15 (5): 449-456 (2014). | 30710 | 24681564 |
The functional influences of common ABCB1 genetic variants on the inhibition of P-glycoprotein by Antrodia cinnamomea extracts. | Sheu, M.J., Teng, Y.N., Chen, Y.Y., Hung, C.C. | PLoS One, 9 (2):e89622 (2014). | 30487 | 24586917 |
RNAi mediates post-transcriptional repression of gene expression in fission yeast Schizosaccharomyces pombe. | Smialowska, A., Djupedal, I., Wang, J., Kylsten, P., Swoboda, P., Ekwall, K. | Biochem. Biophys. Res. Commun., 444 (2): 254-259 (2014). | 28693 | 24462781 |
Mental retardation-related protease, motopsin (prss12), binds to the BRICHOS domain of the integral membrane protein 2a. | Mitsui, S., Osako, Y., Yuri, K. | Cell Biol. Int., 38 (1): 117-123 (2014). | 28604 | 23955961 |
Identification of residues required for stalled-ribosome rescue in the codon-independent release factor YaeJ. | Kogure, H., Handa, Y., Nagata, M., Kanai, N., Guntert, P., Kubota, K., Nameki, N. | Nucleic Acids Res., 42 (5):3152-3163 (2014). | 28464 | 24322300 |
2013
Title | Author | Journal | NBRP RRC ID | PubMed PMID |
---|---|---|---|---|
Methods to study the proliferation and differentiation of cardiac side population (CSP) cells. | Sereti, K.I., Oikonomopoulos, A., Unno, K., Liao, R. | Methods Mol. Biol. 1036: 95-106 (2013). | 57375 | 23807790 |
Establishment of a reporter system to monitor silencing status in induced pluripotent stem cell lines. | Donai, K., Kuroda, K., Guo, Y., So, K.H., Sone, H., Kobayashi, M., Nishimori, K., Fukuda, T. | Anal. Biochem. 443 (1): 104-112 (2013). | 54548 | 23973628 |
Genetic dissection of medial habenula-interpeduncular nucleus pathway function in mice. | Kobayashi, Y., Sano, Y., Vannoni, E., Goto, H., Suzuki, H., Oba, A., Kawasaki, H., Kanba, S., Lipp, H.P., Murphy, N.P., Wolfer, D.P., Itohara, S. | Front. Behav. Neurosci. 7: 17 (2013). | 49492 | 23487260 |
Protein kinase D2 and heat shock protein 90 beta are required for BCL6-associated zinc finger protein mRNA stabilization induced by vascular endothelial growth factor-A. | Miwa, D., Sakaue, T., Inoue, H., Takemori, N., Kurokawa, M., Fukuda, S., Omi, K., Goishi, K., Higashiyama, S. | Angiogenesis, 6 (3): 675-688 (2013). | 48812 | 23515950 |
Spatiotemporal visualization of proHB-EGF ectodomain shedding in living cells. | Inoue, H., Sakaue, T., Ozawa, T., Higashiyama, S. | J. Biochem., 154 (1): 67-76 (2013). | 48811 | 23598347 |
Reducing FLI1 levels in the MRL/lpr lupus mouse model impacts T cell function by modulating glycosphingolipid metabolism. | Richard, E.M., Thiyagarajan, T., Bunni, M.A., Basher, F., Roddy, P.O., Siskind, L.J., Nietert, P.J., Nowling, T.K. | PLoS One, 8 (9): e75175 (2013). | 48755 | 24040398 |
Microglia activation precedes the anti-opioid BDNF and NMDA receptor mechanisms underlying morphine analgesic tolerance. | Matsushita, Y., Omotuyi, I.O., Mukae, T., Ueda, H. | Curr. Pharm. Des. 19 (42): 7355-7361 (2013). | 48549 | 23448475 |
Global analysis of fission yeast mating genes reveals new autophagy factors. | Sun, L.L., Li, M., Suo, F., Liu, X.M., Shen, E.Z., Yang, B., Dong, M.Q., He, W.Z., Du, L.L. | PLoS Genet. 9 (8): e1003715 (2013). | 47467 | 23950735 |
Endogenous gammaretrovirus acquisition in Mus musculus subspecies carrying functional variants of the XPR1 virus receptor. | Bamunusinghe, D., Liu, Q., Lu, X., Oler, A., Kozak, C.A. | J. Virol. 87 (17): 9845-9855 (2013). | 46505 | 23824809 |
Netrin-1-induced activation of Notch signaling mediates glioblastoma cell invasion. | Ylivinkka, I., Hu, Y., Chen, P., Rantanen, V., Hautaniemi, S., Nyman, T.A., Keski-Oja, J., Hyytiainen, M. | J. Cell Sci. 126 (Pt 11): 2459-2469 (2013). | 35154 | 23549787 |
Cell Cycle-Dependent Rho GTPase Activity Dynamically Regulates Cancer Cell Motility and Invasion In Vivo. | Kagawa, Y., Matsumoto, S., Kamioka, Y., Mimori, K., Naito, Y., Ishii, T., Okuzaki, D., Nishida, N., Maeda, S., Naito, A., Kikuta, J., Nishikawa, K., Nishimura, J., Haraguchi, N., Takemasa, I., Mizushima, T., Ikeda, M., Yamamoto, H., Sekimoto, M., Ishii, H., Doki, Y., Matsuda, M., Kikuchi, A., Mori, M., Ishii, M. | PLoS One, 8 (12): e83629 (2013). | 34743 | 24386239 |
Interactions between peptidyl tRNA hydrolase homologs and the ribosomal release factor Mrf1 in S. pombe mitochondria. | Dujeancourt, L., Richter, R., Chrzanowska-Lightowlers, Z.M., Bonnefoy, N., Herbert, C.J. | Mitochondrion 13 (6): 871-880 (2013). | 33953 | 23892058 |
Concerted Action of the Ubiquitin-Fusion Degradation Protein 1 (Ufd1) and Sumo-Targeted Ubiquitin Ligases (STUbLs) in the DNA-Damage Response. | Koehler, J.B., Jorgensen, M.L., Beinoraite, G., Thorsen, M., Thon, G. | PLoS One, 8 (11): e80442 (2013). | 33606 | 24265825 |
Two portable recombination enhancers direct donor choice in fission yeast heterochromatin. | Jakociunas, T., Holm, L.R., Verhein-Hansen, J., Trusina, A., Thon, G. | PLoS Genet., 9 (10): e1003762 (2013). | 33605 | 24204285 |
Evidence for DNA cleavage caused directly by a transfer RNA-targeting toxin. | Shigematsu, M., Ogawa, T., Tanaka, W., Takahashi, K., Kitamoto, H.K., Hidaka, M., Masaki, H. | PLoS One. 8 (9): e75512 (2013). | 31988 | 24069426 |
Death signalobody: inducing conditional cell death in response to a specific antigen. | Tone, Y., Kawahara, M., Kawaguchi, D., Ueda, H., Nagamune, T. | Hum. Gene Ther. Methods 24 (3):141-150 (2013). | 31881 | 23470213 |
Reciprocal virulence and resistance polymorphism in the relationship between Toxoplasma gondii and the house mouse. | Lilue, J., Muller, U.B., Steinfeldt, T., Howard, J.C. | Elife, 2: e01298 (2013). | 30721 | 24175088 |
Involvement of a di-leucine motif in targeting of ABCC1 to the basolateral plasma membrane of polarized epithelial cells. | Emi, Y., Harada, Y., Sakaguchi, M. | Biochem. Biophys. Res. Commun., 441 (1): 89-95 (2013). | 30720 | 24129190 |
Enhanced Antitumor Efficacy of Integrin-targeted Oncolytic Adenovirus AxdAdB3-F/RGD on Bladder Cancer. | Wang, H., Cai, Z., Yang, F., Luo, J., Satoh, M., Arai, Y., Li, D. | Urology, pii: S0090-4295(13) 01369-1 (2013). | 30712 | 24315309 |
Diacylglycerol kinases terminate diacylglycerol signalling during the respiratory burst leading to heterogeneous phagosomal NADPH oxidase activation. | Schlam, D., Bohdanowicz, M., Chatgilialoglu, A., Steinberg, B.E., Ueyama, T., Du, G., Grinstein, S., Fairn, G.D. | J. Biol. Chem., 288 (32): 23090-23104 (2013). | 30709 | 23814057 |
Generation of a large number of functional dendritic cells from human monocytes expanded by forced expression of cMYC plus BMI1. | Haruta, M., Tomita, Y., Imamura, Y., Matsumura, K., Ikeda, T., Takamatsu, K., Nishimura, Y., Senju, S. | Hum. Immunol., 74 (10): 1400-1408 (2013). | 30708 | 23811433 |
MutS stimulates the endonuclease activity of MutL in an ATP-hydrolysis-dependent manner. | Shimada, A., Kawasoe, Y., Hata, Y., Takahashi, T.S., Masui, R., Kuramitsu, S., Fukui, K. | FEBS J., 280 (14): 3467-3479 (2013). | 30705 | 23679952 |
Conservation of two distinct types of 100S ribosome in bacteria. | Ueta, M., Wada, C., Daifuku, T., Sako, Y., Bessho, Y., Kitamura, A., Ohniwa, R.L., Morikawa, K., Yoshida, H., Kato, T., Miyata, T., Namba, K., Wada, A. | Genes Cells, 18 (7): 554-574 (2013). | 30704 | 23663662 |
A proteome-wide visual screen identifies fission yeast proteins localizing to DNA double-strand breaks. | Yu, Y., Ren, J.Y., Zhang, J.M., Suo, F., Fang, X.F., Wu, F., Du, L.L. | DNA Repair (Amst)., 12 (6): 433-443 (2013). | 30703 | 23628481 |
Production of uroporphyrinogen III, which is the common precursor of all tetrapyrrole cofactors, from 5-aminolevulinic acid by Escherichia coli expressing thermostable enzymes. | Hibino, A., Petri, R., Buchs, J., Ohtake, H. | Appl. Microbiol. Biotechnol., 97 (16): 7337-7344 (2013). | 30702 | 23604563 |
WDR81 is necessary for purkinje and photoreceptor cell survival. | Traka, M., Millen, K.J., Collins, D., Elbaz, B., Kidd, G.J., Gomez, C.M., Popko, B. | J. Neurosci., 33 (16): 6834-6844 (2013). | 30700 | 23595742 |
Unique substrate specificity of purine nucleoside phosphorylases from Thermus thermophilus. | Tomoike, F., Kuramitsu, S., Masui, R. | Extremophiles, 17 (3): 505-514 (2013). | 30698 | 23546840 |
Regulation of G-protein signaling via Gnas is required to regulate proximal tubular growth in the Xenopus pronephros. | Zhang, B., Romaker, D., Ferrell, N., Wessely, O. | Dev. Biol., 376(1): 31-42 (2013). | 30695 | 23352791 |
Dimerization of Sir3 via its C-terminal winged helix domain is essential for yeast heterochromatin formation. | Oppikofer, M., Kueng, S., Keusch, J.J., Hassler, M., Ladurner, A.G., Gut, H., Gasser, S.M. | EMBO J. 32 (3): 437-449 (2013). | 30694 | 23299941 |
Direct observation of cell cycle progression in living mouse embryonic stem cells on an extracellular matrix of E-cadherin. | Jovic, D., Sakaue-Sawano, A., Abe, T., Cho, C.C., Nagaoka, N., Miyawaki, A., Akaike, T. | SpringerPlus, 2: 585 (2013). | 30692 | 25674414 |
Structure of the lectin mannose 6-phosphate receptor homology (MRH) domain of glucosidase II, an enzyme that regulates glycoprotein folding quality control in the endoplasmic reticulum. | Olson, L.J., Orsi, R., Alculumbre, S.G., Peterson, F.C., Stigliano, I.D., Parodi, A.J., D’Alessio, C., Dahms, N.M. | J. Biol Chem. ;288 (23): 16460-16475 (2013). | 30216 | 23609449 |
A macrocyclic peptide that serves as a cocrystallization ligand and inhibits the function of a MATE family transporter. | Hipolito, C.J., Tanaka, Y., Katoh, T., Nureki, O., Suga, H. | Molecules, 18 (9): 10514-10530 (2013). | 29446 | 23999725 |
An archaeal homolog of proteasome assembly factor functions as a proteasome activator. | Kumoi, K., Satoh, T., Murata, K., Hiromoto, T., Mizushima, T., Kamiya, Y., Noda, M., Uchiyama, S., Yagi, H., Kato, K. | PLoS One, 8 (3): e60294 (2013). | 29299 | 23555947 |
Crystallization and preliminary X-ray analysis of peptidyl-tRNA hydrolase from Thermus thermophilus HB8. | Matsumoto, A., Shimizu, Y., Takemoto, C., Ueda, T., Uchiumi, T., Ito, K. | Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun., 69 (Pt 3): 332-335 | 29291 | 23519816 |
Genome Sequencing Reveals Loci under Artificial Selection that Underlie Disease Phenotypes in the Laboratory Rat. | Atanur, S.S. et al. | Cell 154 (3): 691-703 (2013). | 28837 | 23890820 |
Identification, characterization and preliminary X-ray diffraction analysis of the rolling-circle replication initiator protein from plasmid pSTK1. | Carr, S.B., Mecia, L.B., Phillips, S.E., Thomas, C.D. | Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun., 69 (Pt 10): 1123-1126 (2013). | 28595 | 24100563 |
Conformational Polymorphism of m(7)GTP in Crystal Structure of the PB2 Middle Domain from Human Influenza A Virus. | Tsurumura, T., Qiu, H., Yoshida, T., Tsumori, Y., Hatakeyama, D., Kuzuhara, T., Tsuge, H. | PLoS One, 8 (11): e82020 (2013). | 28585 | 24312396 |
A novel aromatic carboxylic acid inactivates luciferase by acylation of an enzymatically active regulatory lysine residue. | Nakagomi, M., Fujimaki, N., Ito, A., Toda, T., Fukasawa, H., Shudo, K., Tomita, R. | PLoS One, 8 (9): e75445 (2013). | 28584 | 24066181 |
Isorhamnetin protects against oxidative stress by activating Nrf2 and inducing the expression of its target genes. | Yang, J.H., Shin, B.Y., Han, J.Y., Kim, M.G., Wi, J.E., Kim, Y.W., Cho, I.J., Kim, S.C., Shin, S.M., Ki, S.H. | Toxicol. Appl. Pharmacol., 274 (2): 293-301 (2013). | 28583 | 24211276 |
Transcriptional upregulation of HIF-1 alpha by NF-kappaB/p65 and its associations with beta-catenin/p300 complexes in endometrial carcinoma cells. | Yoshida, T., Hashimura, M., Mastumoto, T., Tazo, Y., Inoue, H., Kuwata, T., Saegusa, M. | Lab. Invest., 93 (11): 1184-1193 (2013). | 28472 | 24042437 |
Functional conservation of Gsdma cluster genes specifically duplicated in the mouse genome. | Tanaka, S., Mizushina, Y., Kato, Y., Tamura, M., Shiroishi, T. | G3 (Bethesda), 3 (10): 1843-1850 (2013). | 28471 | 23979942 |
Postnatal expression of BRAFV600E does not induce thyroid cancer in mouse models of thyroid papillary carcinoma. | Shimamura, M., Nakahara, M., Orim, F., Kurashige, T., Mitsutake, N., Nakashima, M., Kondo, S., Yamada, M., Taguchi, R., Kimura, S., Nagayama, Y. | Endocrinology, 154 (11): 4423-4430 (2013). | 28470 | 23970782 |
E-Cadherin ? Fc Chimeric Protein-Based Biomaterial: Breaking the Barriers in Stem Cell Technology and Regenerative Medicine. | Nag, K., Akaike, T. | Advanced Materials Research, 810: 41-76 (2013). | 28467 | |
Quantitative control of protein S-palmitoylation regulates meiotic entry in fission yeast. | Zhang, M.M., Wu, P.Y., Kelly, F.D., Nurse, P., Hang, H.C. | PLoS Biol., 11 (7): e1001597 (2013). | 28091 | 23843742 |
Transcriptional regulation of mouse mesencephalic astrocyte-derived neurotrophic factor in Neuro2a cells. | Oh-Hashi, K., Hirata, Y., Kiuchi, K. | Cell. Mol. Biol. Lett., 18 (3): 398-415 (2013). | 28090 | 23864333 |
Subnuclear relocalization and silencing of a chromosomal region by an ectopic ribosomal DNA repeat. | Jakociunas, T., Domange Jordo, M., Ait Mebarek, M., Bunner, C.M., Verhein-Hansen, J., Oddershede, L.B., Thon, G. | Proc. Natl. Acad. Sci. U. S. A., 110 (47): E4465-4473 (2013). | 27921 | 24191010 |
Combined sequence-based and genetic mapping analysis of complex traits in outbred rats. | Rat Genome Sequencing and Mapping Consortium, Baud, A, et al. | Nat. Genet., 45 (7): 767-775 (2013). | 27718 | 23708188 |
A mental retardation gene, motopsin/prss12, modulates cell morphology by interaction with seizure-related gene 6. | Mitsui, S., Hidaka, C., Furihata, M., Osako, Y., Yuri, K. | Biochem. Biophys. Res. Commun., 436 (4): 638-644 (2013). | 27716 | 23770366 |
Anti-influenza activity of c60 fullerene derivatives. | Shoji, M., Takahashi, E., Hatakeyama, D., Iwai, Y., Morita, Y., Shirayama, R., Echigo, N., Kido, H., Nakamura, S., Mashino, T., Okutani, T., Kuzuhara, T. | PLoS One, 8 (6): e66337 (2013). | 27715 | 23785493 |
Wnt signaling regulates left-right axis formation in the node of mouse embryos. | Kitajima, K., Oki, S., Ohkawa, Y., Sumi, T., Meno, C. | Dev. Biol., 380 (2): 222-232 (2013). | 27714 | 23707899 |
Resveratrol inhibits LXR alpha-dependent hepatic lipogenesis through novel antioxidant Sestrin2 gene induction. | Jin, S.H., Yang, J.H., Shin, B.Y., Seo, K., Shin, S.M., Cho, I.J., Ki, S.H. | Toxicol. Appl. Pharmacol., 271 (1): 95-105 (2013). | 27713 | 23651738 |
Structural basis for the drug extrusion mechanism by a MATE multidrug transporter. | Tanaka, Y., Hipolito, C.J., Maturana, A.D., Ito, K., Kuroda, T., Higuchi, T., Katoh, T., Kato, H.E., Hattori, M., Kumazaki, K., Tsukazaki, T., Ishitani, R., Suga, H., Nureki, O. | Nature, 496 (7444): 247-251 (2013). | 27309 | 23535598 |
Structural basis for the counter-transport mechanism of a H+/Ca2+ exchanger. | Nishizawa, T., Kita, S., Maturana, A.D., Furuya, N., Hirata, K., Kasuya, G., Ogasawara, S., Dohmae, N., Iwamoto, T., Ishitani, R., Nureki, O. | Science, 341 (6142): 168-172 (2013). | 27307 | 23704374 |
Functional impact of ABCB1 variants on interactions between P-glycoprotein and methadone. | Hung, C.C., Chiou, M.H., Teng, Y.N., Hsieh, Y.W., Huang, C.L., Lane, H.Y. | PLoS One. 2013;8(3):e59419. | 27188 | 23527191 |
Lin28a is a putative factor in regulating cancer stem cell-like properties in side population cells of oral squamous cell carcinoma. | Hayashi, S., Tanaka, J., Okada, S., Isobe, T., Yamamoto, G., Yasuhara, R., Irie, T., Akiyama, C., Kohno, Y., Tachikawa, T., Mishima, K. | Exp Cell Res. 2013 May 1;319(8):1220-8. | 27187 | 23500413 |
MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice. | Cogoi, S., Zorzet, S., Rapozzi, V., Geci, I., Pedersen, E.B., Xodo, L.E. | Nucleic Acids Res., 41(7):4049-4064 (2013). | 27186 | 23471001 |
Haploinsufficiency of the Sec7 guanine nucleotide exchange factor gea1 impairs septation in fission yeast. | Eckler, A.M., Wilder, C., Castanon, A., Ferris, V.M., Lamere, R.A., Perrin, B.A., Pearlman, R., White, B,. Byrd, C., Ludvik, N., Nichols, N., Poole-Sumrall, K., Sztul, E., Styers, M.L. | PLoS One, 8 (2): e56807 (2013). | 27185 | 23457617 |
A novel reporter rat strain that expresses LacZ upon Cre-mediated recombination. | Fukamachi, K., Tanaka, H., Sakai, Y., Alexander, D.B., Futakuchi, M., Tsuda, H., Suzui, M. | Genesis, 51 (4): 268-274 (2013). | 27184 | 23349063 |
Excitatory cortical neurons with multipolar shape establish neuronal polarity by forming a tangentially oriented axon in the intermediate zone. | Hatanaka, Y., Yamauchi, K.. | Cereb. Cortex, 23 (1): 105-113 (2013). | 27182 | 22267309 |
The ancestor of extant Japanese fancy mice contributed to the mosaic genomes of classical inbred strains. | Takada, T., Ebata, T., Noguchi, H., Keane, T.M., Adams, D.J., Narita, T., Shin-I, T., Fujisawa, H., Toyoda, A., Abe, K., Obata, Y., Sakaki, Y., Moriwaki, K., Fujiyama, A., Kohara, Y., Shiroishi, T. | Genome Res., 23 (8): 1329-1338 (2013). | 21786 | 23604024 |
Display of active beta-glucosidase on the surface of Schizosaccharomyces pombe cells using novel anchor proteins. | Tanaka, T., Matsumoto, S., Yamada, M., Yamada, R., Matsuda, F., Kondo, A. | Appl. Microbiol. Biotechnol., 97 (10): 4343-4352 (2013). | 21120 | 23385477 |
2012
Title | Author | Journal | NBRP RRC ID | PubMed PMID |
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Live-cell studies of p300/CBP histone acetyltransferase activity and inhibition. | Dancy, B.M., Crump, N.T., Peterson, D.J., Mukherjee, C., Bowers, E.M., Ahn, Y.H., Yoshida, M., Zhang, J., Mahadevan, L.C., Meyers, D.J., Boeke, J.D., Cole, P.A. | Chembiochem. 13 (14): 2113-2121 (2012). | 55048 | 22961914 |
Efficient establishment of pig embryonic fibroblast cell lines with conditional expression of the simian vacuolating virus 40 large T fragment. | Fukuda, T., Katayama, M., Yoshizawa, T., Eitsuka, T., Mizukami, H., Nakagawa, K., Ito, H., Komagata, H., Song, S., Roh, S., Hoshino, Y., Sato, E., Hanada, H., Nishimori, K., Miyazawa, T., Uchida, T. | Biosci. Biotechnol. Biochem. 76 (7): 1372-1377 (2012). | 55037 | 22785463 |
Generation of corneal epithelial cells from induced pluripotent stem cells derived from human dermal fibroblast and corneal limbal epithelium. | Hayashi, R., Ishikawa, Y., Ito, M., Kageyama, T., Takashiba, K., Fujioka, T., Tsujikawa, M., Miyoshi, H., Yamato, M., Nakamura, Y., Nishida, K. | PLoS One 7 (9): e45435 (2012). | 53854 | 23029008 |
Structural and functional characterization of Rpn12 identifies residues required for Rpn10 proteasome incorporation. | Boehringer, J., Riedinger, C., Paraskevopoulos, K., Johnson, E.O., Lowe, E.D., Khoudian, C., Smith, D., Noble, M.E., Gordon, C., Endicott, J.A. | Biochem. J. 448 (1): 55-65 (2012). | 47483 | 22906049 |
Phosphorylation-dependent interactions between Crb2 and Chk1 are essential for DNA damage checkpoint. | Qu, M., Yang, B., Tao, L., Yates, J.R. 3rd, Russell, P., Dong, M.Q., Du, L.L. | PLoS Genet. 8 (7): e1002817 (2012). | 47465 | 22792081 |
Role of activation-induced cytidine deaminase in the progression of follicular lymphoma. | Shikata, H., Yakushijin, Y., Matsushita, N., Sakai, A., Sugita, A., Nakamura, N., Yamanouchi, J., Azuma, T., Hato, T., Yasukawa, M. | Cancer Sci. 103 (3): 415-421 (2012). | 45805 | 22168746 |
Hypothermia-induced tyrosine phosphorylation of SIRP alpha in the brain. | Maruyama, T., Kusakari S, Sato-Hashimoto M, Hayashi Y, Kotani T, Murata Y, Okazawa H, Oldenborg PA, Kishi S, Matozaki T, Ohnishi H. | J. Neurochem., 121 (6): 891-902 (2012). | 35683 | 22468987 |
Stat3 inhibition in neural lineage cells. | Chiba, T., Mack, L., Delis, N., Brill, B., Groner, B. | Horm. Mol. Biol. Clin. Investig. 10 (2): 255-263 (2012). | 28469 | 25436682 |
TATA-binding protein (TBP)-like protein is required for p53-dependent transcriptional activation of upstream promoter of p21Waf1/Cip1 gene. | Suzuki, H., Ito, R., Ikeda, K., Tamura, T.A. | J. Biol. Chem., 287 (24): 19792-19803 (2012). | 28093 | 22511763 |
Origins of albino and hooded rats: implications from molecular genetic analysis across modern laboratory rat strains. | Kuramoto, T., Nakanishi, S., Ochiai, M., Nakagama, H., Voigt, B., Serikawa, T. | PLoS One, 7 (8): e43059 (2012). | 27742 | 22916206 |
Casitas B-cell lymphoma mutation in childhood T-cell acute lymphoblastic leukemia. | Saito, Y., Aoki, Y., Muramatsu, H., Makishima, H., Maciejewski, J.P., Imaizumi, M., Rikiishi, T., Sasahara, Y., Kure, S., Niihori, T., Tsuchiya, S., Kojima, S., Matsubara, Y. | Leuk Res., 36 (8): 1009-1015 (2012). | 27183 | 22591685 |
Heat-shock protein 70 from plant biofactories of recombinant antigens activate multiepitope-targeted immune responses. | Buriani, G., Mancini, C., Benvenuto, E., Baschieri, S. | Plant Biotechnol J., 10 (3): 363-371 (2012). | 27181 | 22221920 |
The differentiation and isolation of mouse embryonic stem cells toward hepatocytes using galactose-carrying substrata. | Meng, Q., Haque, A., Hexig, B., Akaike, T. | Biomaterials, 33 (5): 1414-1427 (2012). | 27180 | 22118818 |
Surveillance of spontaneous breast cancer metastasis by TRAIL-expressing CD34? cells in a xenograft model. | Rossini, A., Giussani, M., Giacomini, A., Guarnotta, C., Tagliabue, E., Balsari, A. | Breast Cancer Res. Treat., 136 (2): 457-467 (2012). | 21542 | 23053664 |
Molecular cytogenetic identification and characterization of Robertsonian chromosomes in the large Japanese field mouse (Apodemus speciosus) using FISH. | Yamagishi, M., Matsubara, K., Sakaizumi, M. | Zoolog. Sci., 29 (10): 709-713 (2012). | 21541 | 23030344 |
Transcriptional regulation of the interleukin-11 gene by oncogenic Ras. | Shin, S.Y., Choi, C., Lee, H.G., Lim, Y., Lee, Y.H. | Carcinogenesis, 33 (12): 2467-2476 (2012). | 21540 | 23027619 |
The E1 protein of human papillomavirus type 16 is dispensable for maintenance replication of the viral genome. | Egawa, N., Nakahara, T., Ohno, S., Narisawa-Saito, M., Yugawa, T., Fujita, M., Yamato, K., Natori, Y., Kiyono, T. | J. Virol., 86 (6): 3276-3283 (2012). | 21539 | 22238312 |
Structural basis for translation termination by archaeal RF1 and GTP-bound EF1alpha complex. | Kobayashi, K., Saito, K., Ishitani, R., Ito, K., Nureki, O. | Nucleic Acids Res., 40 (18): 9319-9328 (2012). | 21538 | 22772989 |
Osterix regulates calcification and degradation of chondrogenic matrices through matrix metalloproteinase 13 (MMP13) expression in association with transcription factor Runx2 during endochondral ossification. | Nishimura, R., Wakabayashi, M., Hata, K., Matsubara, T., Honma, S., Wakisaka, S., Kiyonari, H., Shioi, G., Yamaguchi, A., Tsumaki, N., Akiyama, H., Yoneda, T. | J. Biol. Chem., 287 (40): 33179-33090 (2012). | 21537 | 22869368 |
Efficient recombinant production in mammalian cells using a novel IR/MAR gene amplification method. | Araki, Y., Hamafuji, T., Noguchi, C., Shimizu, N. | PLoS One, 7 (7): e41787 (2012). | 21536 | 22844523 |
Development of an optimized tetracycline-inducible expression system to increase the accumulation of interleukin-10 in tobacco BY-2 suspension cells. | Bortesi, L., Rademacher, T., Schiermeyer, A., Schuster, F., Pezzotti, M., Schillberg, S. | BMC Biotechnol.,12: 40 (2012). | 21535 | 22784336 |
Differentiation of human embryonic stem cells and human induced pluripotent stem cells into steroid-producing cells. | Sonoyama, T., Sone, M., Honda, K., Taura, D., Kojima, K., Inuzuka, M., Kanamoto, N., Tamura, N., Nakao, K. | Endocrinology, 153 (9): 4336-4345 (2012). | 21534 | 22778223 |
Enhanced expression of myogenic differentiation factors and skeletal muscle proteins in human amnion-derived cells via the forced expression of MYOD1. | Akizawa, Y., Kanno, H., Kawamichi, Y., Matsuda, Y., Ohta, H., Fujii, H., Matsui, H., Saito, K. | Brain Dev., 35 (4): 349-355 (2012). | 21533 | 22727434 |
In-cell NMR of intrinsically disordered proteins in prokaryotic cells. | Ito, Y., Mikawa, T., Smith, B.O. | Methods Mol. Biol., 895: 19-31 (2012). | 21532 | 22760309 |
Nrf2-ARE pathway regulates induction of Sestrin-2 expression. | Shin, B.Y., Jin, S.H., Cho, I.J., Ki, S.H. | Free Radic. Biol. Med., 53 (4): 834-841 (2012). | 21531 | 22749810 |
Establishment of single-cell screening system for the rapid identification of transcriptional modulators involved in direct cell . | Shin, J.W., Suzuki, T., Ninomiya, N., Kishima, M., Hasegawa, Y., Kubosaki, A., Yabukami, H., Hayashizaki, Y., Suzuki, H. | Nucleic Acids Res., 40 (21): e165 (2012). | 21530 | 22879381 |
Novel regulatory mechanism and functional implication of plasminogen activator inhibitor-1 (PAI-1) expression in CpG-ODN-stimulated macrophages. | Thapa, B., Kim, Y.H., Kwon, H.J., Kim, D.S. | Mol. Immunol. 49 (4): 572-581 (2012). | 21529 | 22078208 |
Opposing regulation of PROX1 by interleukin-3 receptor and NOTCH directs differential host cell fate reprogramming by Kaposi sarcoma herpes virus. | Yoo, J., Lee, H.N., Choi, I., Choi, D., Chung, H.K., Kim, K.E., Lee, S., Aguilar, B., Kang, J., Park, E., Lee, Y.S., Maeng, Y.S,. Kim, N.Y., Koh, C.J., Hong, Y.K. | PLoS Pathog. 8 (6): e1002770 (2012). | 21527 | 22719258 |
Reduction of NOTCH1 expression pertains to maturation abnormalities of keratinocytes in squamous neoplasms. | Sakamoto, K., Fujii, T., Kawachi, H., Miki, Y., Omura, K., Morita, K., Kayamori, K., Katsube, K., Yamaguchi, A. | Lab. Invest., 92 (5): 688-702 (2012). | 21526 | 22330335 |
Suppression of feline coronavirus replication in vitro by cyclosporin A. | Tanaka, Y., Sato, Y., Osawa, S., Inoue, M., Tanaka, S., Sasaki, T. | Vet. Res., 43 (1): 41 (2012). | 21525 | 22546085 |
Constitutively active Cullin-RING-Ligases fail to rescue loss of NEDD8 conjugation in Schizosaccharomyces pombe. | Girdwood, D., Robertson, M., Gordon, C. | FEBS Lett., 586 (10): 1522-1528 (2012). | 21524 | 22673520 |
Discovery and Analysis of Cofactor-dependent Phosphoglycerate Mutase Homologs as Novel Phosphoserine Phosphatases in Hydrogenobacter thermophilus. | Chiba, Y., Oshima, K., Arai, H., Ishii, M., Igarashi, Y. | J. Biol Chem. 287 (15): 11934-11941 (2012). | 21521 | 22337887 |
Homo-catiomer integration into PEGylated polyplex micelle from block-catiomer for systemic anti-angiogenic gene therapy for fibrotic pancreatic tumors. | Chen Q., Osada K, Ishii T, Oba M, Uchida S, Tockary TA, Endo T, Ge Z, Kinoh H, Kano MR, Itaka K, Kataoka K. | Biomaterials, 33 (18): 4722-4730 (2012). | 21520 | 22444644 |
Growth control of genetically modified cells using an antibody/c-Kit chimera. | Kaneko, E., Kawahara, M., Ueda, H., Nagamune, T. | J. Biosci. Bioeng., 113 (5): 641-646 (2012). | 21519 | 22227120 |
Crystal structure of hypothetical protein TTHB210, controlled by the σE/anti-σE regulatory system in Thermus thermophilus HB8, reveals a novel homodecamer. | Agari, Y., Kuramitsu, S., Shinkai, A. | Proteins 80 (3): 958-962 (2012). | 21517 | 22231934 |
Surface plasmon resonance-biosensor detects the diversity of responses against epidermal growth factor in various carcinoma cell lines. | Hiragun, T., Yanase, Y., Kose, K., Kawaguchi, T., Uchida, K., Tanaka, S., Hide, M. | Biosens. Bioelectron., 32 (1): 202-207 (2012). | 17607 | 22204782 |
Identification and characterization of Hoxa9 binding sites in hematopoietic cells. | Huang, Y., Sitwala, K., Bronstein, J., Sanders, D., Dandekar, M., Collins, C., Robertson, G., Macdonald, J., Cezard, T., Bilenky, M., Thiessen, N., Zhao, Y., Zeng, T., Hirst, M., Hero, A., Jones, S., Hess, J.L. | Blood 119 (2): 388-398 (2012). | 12715 | 22072553 |
Derivation of rat embryonic stem cells and generation of protease-activated receptor-2 knockout rats. | Yamamoto S., Nakata M, Sasada R, Ooshima Y, Yano T, Shinozawa T, Tsukimi Y, Takeyama M, Matsumoto Y, Hashimoto T. | Transgenic Res., 21 (4): 743-755 (2012). | 12712 | 22002084 |
2011
Title | Author | Journal | NBRP RRC ID | PubMed PMID |
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Drug-induced cell cycle modulation leading to cell-cycle arrest, nuclear mis-segregation, or endoreplication. | Sakaue-Sawano, A., Kobayashi, T., Ohtawa, K., Miyawaki, A. | BMC Cell Biol. 12: 2 (2011). | 49239 | 21226962 |
Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors. | Sekiya, S., Suzuki, A. | Nature 475 (7356): 390-393 (2011). | 48008 | 21716291 |
Bacillus anthracis tubulin-related protein Ba-TubZ assembles force-generating polymers. | Srinivasan, R., Mishra, M., Leong, F.Y., Chiam, K.H., Balasubramanian, M. | Cytoskeleton (Hoboken) 68(9): 501-511 (2011). | 47485 | 21780309 |
Charge-conversion ternary polyplex with endosome disruption moiety: a technique for efficient and safe gene delivery. | Lee, Y., Miyata, K., Oba, M., Ishii, T., Fukushima, S., Han, M., Koyama, H., Nishiyama, N., Kataoka, K. | Angew. Chem. Int. Ed. Engl. 47 (28): 5163-5166 (2008). | 34544 | 18528828 |
NF-kappaB plays an important role in indoxyl sulfate-induced cellular senescence, fibrotic gene expression, and inhibition of proliferation in proximal tubular cells. | Shimizu, H., Bolati, D., Adijiang, A., Muteliefu, G., Enomoto, A., Nishijima, F., Dateki, M., Niwa, T. | Am. J. Physiol. Cell Physiol. 301 (5): C1201-12 (2011). | 31848 | 21832251 |
Forced notch signaling inhibits commissural axon outgrowth in the developing chick central nerve system. | Shi, M., Liu, Z., Lv, Y., Zheng, M., Du, F., Zhao, G., Huang, Y., Chen, J., Han, H., Ding, Y. | PLoS One, 6 (1): e14570 (2011). | 30488 | 21283742 |
Control of singular cell cycle synchronization of mouse ES cells for hepatocyte differentiation on E-cadherin substratum. | Jovic, D., Haque, A., Exig, B., Nagaoka, m., Akaike, T. | J. Biotechnol. Biomaterial, 1: 6 (2011). | 28468 | |
Pseudouridine at position 55 in tRNA controls the contents of other modified nucleotides for low-temperature adaptation in the extreme-thermophilic eubacterium Thermus thermophilus. | Ishida, K., Kunibayashi, T., Tomikawa, C., Ochi, A., Kanai, T., Hirata, A., Iwashita, C., Hori, H. | Nucleic Acids Res., 39 (6): 2304-2318 (2011). | 27711 | 21097467 |
Phenotype of single hepatocytes expressing an activated version of beta-catenin in liver of transgenic mice. | Schreiber S, Rignall B, Braeuning A, Marx-Stoelting P, Ott T, Buchmann A, Hammad S, Hengstler JG, Schwarz M, Kohle C. | J. Mol. Histol., 42 (5): 393-400 (2011). | 27179 | 21822615 |
Coordinate regulation of cytochrome P450 1a1 expression in mouse liver by the aryl hydrocarbon receptor and the beta-catenin pathway. | Braeuning A, Kohle C, Buchmann A, Schwarz M. | Toxicol .Sci., 122 (1): 16-25 (2011). | 27178 | 21498875 |
YC-1, a novel potential anticancer agent, inhibit multidrug-resistant protein via cGMP-dependent pathway. | Hung, C.C., Liou, H.H. | Invest New Drugs 29 (6): 1337-1346 (2011). | 21522 | 20676745 |
A single amino acid limits the substrate specificity of Thermus thermophilus uridine-cytidine kinase to cytidine. | Tomoike, F., Nakagawa, N., Kuramitsu, S., Masui, R. | Biochemistry 50( 21): 4597-4607 (2011). | 21516 | 21539325 |
Ultrasound-mediated interferon beta gene transfection inhibits growth of malignant melanoma. | Yamaguchi, K., Feril, .L.B. Jr., Tachibana, K., Takahashi, A., Matsuo, M., Endo, H., Harada, Y., Nakayama, J. | Biochem. Biophys. Res. Commun. 411 (1): 137-142 (2011). | 21514 | 21723255 |
Adeno-associated virus Rep-mediated targeting of integrase-defective retroviral vector DNA circles into human chromosome 19. | Huang, S., Kawabe, Y., Ito, A., Kamihira, M. | Biochem. Biophys. Res. Commun. 417 (1): 78-83 (2011). | 12714 | 22138242 |
RB1CC1 suppresses type II collagen synthesis in chondrocytes, and causes dwarfism. | Nishimura, I., Chano, T., Kita, H., Matsusue, Y., Okabe, H. | J. Biol. Chem., 286 (51): 43925-43932 (2011). | 12713 | 22049074 |
RNF43 interacts with NEDL1 and regulates p53-mediated transcription. | Shinada, K., Tsukiyama, T., Sho, T., Okumura, F., Asaka, M., Hatakeyama, S. | Biochem. Biophys. Res. Commun., 404 (1): 143-147 (2011). | 12711 | 21108931 |
Effect of integrin targeting and PEG shielding on polyplex micelle internalization studied by live-cell imaging. | Mickler, F.M., Vachutinsky, Y., Oba, M., Miyata, K., Nishiyama, N., Kataoka, K., Brauchle, C., Ruthardt, N. | J. Control Release, 156 (3): 364-373 (2011). | 12710 | 21843561 |
Circadian transcriptional factor DBP regulates expression of Kiss1 in the anteroventral periventricular nucleus. | Xu, Z., Kaga, S., Tsubomizu, J., Fujisaki, J., Mochiduki, A., Sakai, T., Tsukamura, H., Maeda, K., Inoue, K., Adachi, A.A. | Mol Cell Endocrinol. 339 (1-2): 90-97 (2011). | 12709 | 21458520 |
Wt1a, Foxc1a, and the Notch mediator Rbpj physically interact and regulate the formation of podocytes in zebrafish. | O’Brien, L.L., Grimaldi, M., Kostun, Z., Wingert, R.A., Selleck, R., Davidson, A.J. | Dev. Biol., 358 (2): 318-330 (2011). | 12708 | 21871448 |
JNK1 Phosphorylation of Cdt1 Inhibits Recruitment of HBO1 Histone Acetylase and Blocks Replication Licensing in Response to Stress. | Miotto, B., Struhl, K. | Mol. Cell., 4 4(1): 62-71 (2011). | 12707 | 21856198 |
G4-DNA Formation in the HRAS Promoter and Rational Design of Decoy Oligonucleotides for Cancer Therapy. | Membrino, A., Cogoi, S., Pedersen, E.B., Xodo, L.E. | PLoS One. 6 (9): e24421 (2011). | 12706 | 21931711 |
Inhibition of Ubiquitin ligase F-box and WD repeat domain-containing 7(alpha) (Fbw7(alpha}) causes hepatosteatosis through the Kruppel-like factor 5 (KLF5)/PPAR(gamma)2 pathway, but not SREBP-1c in mice. | Kumadaki, S., Karasawa, T., Matsuzaka, T., Ema, M., Nakagawa, Y., Nakakuki, M., Saito, R., Yahagi, N., Iwasaki, H., Sone, H., Takekoshi, K., Yatoh, S., Kobayashi, K., Takahashi, A., Suzuki, H., Takahashi, S., Yamada, N., Shimano, H. | J. Biol. Chem., 286 (47): 40835-40846 (2011). | 12705 | 21911492 |
Water-Soluble Extract of Pacific Krill Prevents Triglyceride Accumulation in Adipocytes by Suppressing PPARgamma and C/EBPalpha Expression. | Yamada, H., Ueda, T., Yano, A. | PLoS One 6 (7): e21952 (2011). | 12704 | 21760932 |
Glucosidase II and N-glycan mannose content regulate the half-lives of monoglucosylated species in vivo. | Stigliano, I.D., Alculumbre, S.G., Labriola, C.A., Parodi, A.J., D’Alessio, C. | Mol. Biol. Cell 22 (11): 1810-1823 (2011). | 12703 | 21471007 |
An expression profile analysis of ES cell-derived definitive endodermal cells and Pdx1-expressing cells. | Ogaki, S., Harada, S., Shiraki, N., Kume, K., Kume, S. | BMC Dev. Biol., 11, 13 (2011). | 12702 | 21362171 |
A genome wide study in fission yeast reveals nine PPR proteins that regulate mitochondrial gene expression. | Kuhl, I., Dujeancourt, L., Gaisne, M., Herbert, C.J., Bonnefoy, N. | Nucleic Acids Res., 39 (18): 8029-8041 (2011). | 12549 | 21727087 |
Direct and differential effects of stem cell factor on the neovascularization activity of endothelial progenitor cells. | Kim, K.L., Meng, Y., Kim, J.Y., Baek, E.J., Suh, W. | Cardiovasc Res. 92 (1): 132-140 (2011). | 12245 | 21636540 |
Anti-influenza activity of marchantins, macrocyclic bisbibenzyls contained in liverworts. | Iwai, Y., Murakami, K., Gomi, Y., Hashimoto, T., Asakawa, Y., Okuno, Y., Ishikawa, T., Hatakeyama, D., Echigo, N., Kuzuhara, T. | PLoS One 6 (5): e19825 (2011). | 12232 | 21625478 |
Mechanisms by which Interleukin-6 Regulates Prostate Specific Antigen Gene Expression in Prostate LNCaP Carcinoma Cells. | Tsui K.H., Lin Y.F., Chen Y.H., Chang P.L., Juang H.H. | J. Androl. 32 (4): 383-393 (2011). | 11935 | 21051589 |
The effect of recombinant E-cadherin substratum on the differentiation of endoderm-derived hepatocyte-like cells from embryonic stem cells. | Haque, A., Hexig, B., Meng, Q., Hossain, S., Nagaoka, M., Akaike, T. | Biomaterials, 32, 2032-2042 (2011). | 11934 | 21163520 |
Plasminogen activator uPA is a direct transcriptional target of the JAG1-Notch receptor signaling pathway in breast cancer. | Shimizu, M., Cohen, B., Goldvasser, P., Berman, H., Virtanen, C., Reedijk, M. | Cancer Res., 71, 277-286 (2011) . | 11933 | 21199807 |
Regulation of nonclassical fgf1 release and fgf-dependent cell transformation by CBF1-mediated notch signaling. | Kacer, D., McIntire, C., Kirov, A., Kany, E., Roth, J., Liaw, L., Small, D., Friesel, R., Basilico, C., Tarantini, F., Verdi, J., Prudovsky, I. | J. Cell. Physiol., 226 (11): 3064-3075 (2011). | 11932 | 21302306 |
2010
Title | Author | Journal | NBRP RRC ID | PubMed PMID |
---|---|---|---|---|
Anti-influenza activity of phenethylphenylphthalimide analogs derived from thalidomide. | Iwai Y., Takahashi H., Hatakeyama D., Motoshima K., Ishikawa M., Sugita K., Hashimoto Y., Harada Y., Itamura S., Odagiri T., Tashiro M., Sei Y., Yamaguchi K., Kuzuhara T. | Bioorg. Med. Chem., 18, 5379-5390 (2010). | 6868 | 20538468 |
The KRAS promoter responds to Myc-associated zinc finger and poly(ADP-ribose) polymerase 1 proteins, which recognize a critical quadruplex-forming GA-element. | Cogoi S., Paramasivam M., Membrino A., Yokoyama KK., Xodo L.E. | J. Biol. Chem., 285, 22003-22016 (2010). | 6867 | 20457603 |
Involvement of ubiquitous and tale transcription factors, as well as liganded RXR alpha, in the regulation of human SOX2 gene expression in the NT2/D1 embryonal carcinoma cell line. | Milena, M., Gordana, N., Natasa, K.G., Krstic, A., Marija, M., Danijela, D., Milena, S. | Arch. Biol. Sci., Belgrade, 62, 199-210 (2010). | 6866 | |
Stimulation of p53 Transactivation Ability by Nicastrin in Mouse Fibroblasts. | Koshida, T., Kitagawa, M., Iwase, K., Takiguchi, M., Hiwasa, T. | SRX Biology, 2010 , Article ID 606391 | 6865 | |
Osteogenic differentiation of mouse mesenchymal progenitor cell, Kusa-A1 is promoted by mammalian transcriptional repressor Rbpj. | Wang S., Kawashima N., Sakamoto K., Katsube K., Umezawa A., Suda H. | Biochem. Biophys. Res. Commun., 400, 39-45 (2010). | 6863 | 20691157 |
Molecular engineering and validation of an oncolytic herpes simplex virus type 1 transcriptionally targeted to midkine-positive tumors. | Maldonado AR., Klanke C., Jegga AG., Aronow BJ., Mahller YY., Cripe TP., Crombleholme TM. | J. Gene. Med., 12, 613-623 (2010). | 6862 | 20603890 |
Integrin alpha5beta1 is necessary for regulation of radial migration of cortical neurons during mouse brain development. | Marchetti G., Escuin S., van der Flier A., De Arcangelis A., Hynes RO., Georges-Labouesse E. | Eur. J. Neurosci., 31, 399-409, (2010). | 6856 | 20105241 |
An accumulative site-specific gene integration system using Cre recombinase-mediated cassette exchange. | Kameyama Y., Kawabe Y., Ito A., Kamihira M. | Biotechnol. Bioeng., 105, 1106-1114 (2010). | 6855 | 19998287 |
Specific splicing defects in S. pombe carrying a degron allele of the Survival of Motor Neuron gene. | Campion Y., Neel H., Gostan T., Soret J., Bordonne R. | EMBO J. 29 (11): 1817-1829 (2010). | 6197 | 20400941 |
Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1 plasmid DNA carried by RGD-modified crosslinked polyplex micelles. | Vachutinsky Y., Oba M., Miyata K., Hiki S., Kano M.R., Nishiyama N., Koyama H., Miyazono K., Kataoka K. | J. Control. Release (2010). | 6195 | 20138936 |
Genetic variation of melatonin productivity in laboratory mice under domestication. | Kasahara T., Abe K., Mekada K., Yoshiki A., Kato T. | Proc. Natl. Acad. Sci. U S A., 107, 6412-6417 (2010). | 5992 | 20308563 |
Myogenic differentiation in atrium-derived adult cardiac pluripotent cells and the transcriptional regulation of GATA4 and myogenin on ANP promoter. | Kamrul Hasan M, Komoike Y., Tsunesumi SI., Nakao R., Nagao H., Ma.tsuoka R., Kawaguchi N. | Genes Cells, 15, 439-453 (2010). | 5831 | 20384792 |
Tumor necrosis factor-related apoptosis-inducing ligand 1 (TRAIL1) enhances the transition of red blood cells from the larval to adult type during metamorphosis in Xenopus. | Tamura K., Mawaribuchi S., Yoshimoto S., Shiba T., Takamatsu N., Ito M. | Blood, 115, 850-859 (2010). | 5825 | 19965624 |
Mature acinar cells are refractory to carcinoma development by targeted activation of Ras oncogene in adult rats. | Tanaka H., Fukamachi K., Futakuchi M., Alexander D.B., Long N., Tamamushi S., Minami K., Seino S., Ohara H., Joh T., Tsuda H. | Cancer Sci., 101, 341-346 (2010). | 5824 | 19917056 |
N7-Methylguanine at position 46 (m7G46) in tRNA from Thermus thermophilus is required for cell viability at high temperatures through a tRNA modification network. | Tomikawa C., Yokogawa T., Kanai T., Hori H. | Nucleic Acids Res., 38, 942-957 (2010). | 5823 | 19934251 |
Bifurcation of Toll-like receptor 9 signaling by adaptor protein 3. | Sasai, M., Linehan, M.M., Iwasaki, A. | Science 329 (5998): 1530-1534 (2010). | 52880 | 20847273 |
Rapid bacterial artificial chromosome modification for large-scale mouse transgenesis. | Gong, S., Kus, L., Heintz, N. | Nat. Protoc., 5 (10), 1678-1696 (2010). | 48832 | 20885380 |
Splicing-dependent NMD does not require the EJC in Schizosaccharomyces pombe. | Wen, J., Brogna, S. | EMBO J. 29 (9): 1537-1551 (2010). | 47473 | 20360683 |
Involvement of Notch1 inhibition in serum-stimulated glia and oligodendrocyte differentiation from human mesenchymal stem cells. | Lee, Y.J., Hung, S.C., Chu, M.S. | Stem Cells and Cloning: Advances and Applications, 3: 165-173 (2010). | 28466 | 24198522 |
Generation of induced pluripotent stem cells in rabbits: potential experimental models for human regenerative medicine. | Honda A., Hirose M., Hatori M., Matoba S., Miyoshi H., Inoue K., Ogura A. | J. Biol. Chem., 285, 31362-31369 (2010). | 12725 | 20670936 |
Omnipotent role of archaeal elongation factor 1 alpha (EF1alpha) in translational elongation and termination, and quality control of protein synthesis. | Saito, K., Kobayashi, K., Wada, M., Kikuno, I., Takusagawa, A., Mochizuki, M., Uchiumi, T., Ishitani, R., Nureki, O., Ito, K. | Proc. Natl. Acad. Sci. U S A., 107 (45): 19242-19247 (2010). | 12717 | 20974926 |
Structural basis for mRNA surveillance by archaeal Pelota and GTP-bound EF1 alpha complex. | Kobayashi, K., Kikuno, I., Kuroha, K., Saito, K., Ito, K., Ishitani, R., Inada, T., Nureki, O. | Proc. Natl. Acad. Sci. U S A., 107 (41): 17575-17579 (2010). | 12716 | 20876129 |
Efficient Gene Transduction in HER2-Expressing Cells by Two Recombinant Adenovirus Vectors with HER2 Promotor and Cre/loxP System. | Nodagashira T., Odagiri H., Ikenaga S.K., Murayama M., Sato T., Hakamada K. | Hirosaki Med. J., 61: 26-34 (2010). | 11963 | |
Transcriptional regulation of cGMP-dependent protein kinase II (cGK-II) in chondrocytes. | Yuasa, K., Uehara, S., Nagahama, M., Tsuji, A. | Biosci. Biotechnol. Biochem., 74 (1), 44-49 (2010). | 11946 | 20057151 |
Human CD34+ cells engineered to express membrane-bound tumor necrosis factor-related apoptosis-inducing ligand target both tumor cells and tumor vasculature. | Lavazza, C., Carlo-Stella, C., Giacomini, A., Cleris, L., Righi, M., Sia, D., Di Nicola, M., Magni, M., Longoni, P., Milanesi, M., Francolini, M., Gloghini, A., Carbone, A., Formelli, F., Gianni, A.M. | Blood, 115 (11), 2231-2240 (2010). | 11945 | 20075160 |
Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble flt-1. | Oba M, Vachutinsky Y, Miyata K, Kano MR, Ikeda S, Nishiyama N, Itaka K, Miyazono K, Koyama H, Kataoka K. | Mol. Pharm. 7 (2), 501-509 (2010). | 11943 | 20178335 |
A novel single-stranded DNA-specific 3′-5′ exonuclease, Thermus thermophilus exonuclease I, is involved in several DNA repair pathways. | Shimada, A., Masui, R., Nakagawa, N., Takahata, Y., Kim, K., Kuramitsu, S., Fukui, K. | Nucleic Acids Res., 38 (17), 5692-5705 (2010). | 11941 | 20457749 |
Identification of DAF1/CD55, a novel definitive endoderm marker. | Shiraki, N., Harada, S., Ogaki, S., Kume, K., Kume, S. | Cell Struct. Funct., 35 (2), 73-80 (2010). | 11940 | 20526042 |
Reorganization of the growth pattern of Schizosaccharomyces pombe in invasive filament formation. | Dodgson, J., Brown, W., Rosa, C.A., Armstrong, J. | Eukaryot. Cell, 9, 1788-1797 (2010). | 11938 | 20870879 |
Polyplex micelles prepared from omega-cholesteryl PEG-polycation block copolymers for systemic gene delivery. | Oba M., Miyata K., Osada K., Christie R.J., Sanjoh M., Li W., Fukushima S., Ishii T., Kano M.R., Nishiyama N., Koyama H., Kataoka K. | Biomaterials, 32 (2): 652-663 (2010) | 11936 | 20932567 |
Identification of dynamin-2-mediated endocytosis as a new target of osteoporosis drugs, bisphosphonates. | Masaike Y., Takagi T., Hirota M., Yamada J., Ishihara S., Yung T.M., Inoue T., Sawa C., Sagara H., Sakamoto S., Kabe Y., Takahashi Y., Yamaguchi Y., Handa H. | Mol. Pharmacol., 77, 262-269 (2010). | 11017 | 19903825 |
2009
Title | Author | Journal | NBRP RRC ID | PubMed PMID |
---|---|---|---|---|
Novel immortalized human fetal liver cell line, cBAL111, has the potential to differentiate into functional hepatocytes. | Deurholt T., van Til N.P., Chhatta A.A., ten Bloemendaal L., Schwartlander R., Payne C., Plevris J.N., Sauer I.M., Chamuleau R.A., Elferink R.P., Seppen J., Hoekstra R. | BMC Biotechnol., 9: 89 (2009). | 6193 | 19845959 |
Construction of a model cell line for the assay of MDR1 (multi drug resistance gene-1) substrates/inhibitors using HeLa cells. | Kugawa F., Suzuki T., Miyata M., Tomono K., Tamanoi F. | Pharmazie, 64, 296-300 (2009). | 6192 | 19530439 |
An animal model of preclinical diagnosis of pancreatic ductal adenocarcinomas. | Fukamachi K., Tanaka H., Hagiwara Y., Ohara H., Joh T., Iigo M., Alexander D.B., Xu J., Long, N., Takigahira M., Yanagihara K., Hino O., Saito I., Tsuda H. | Biochem. Biophys. Res. Commun., 390, 636-641 (2009). | 5822 | 19818733 |
Glucosidase II beta subunit modulates N-glycan trimming in fission yeasts and mammals. | Stigliano I.D., Caramelo J.J., Labriola C.A., Parodi A.J., D’Alessio C. | Mol. Biol. Cell, 20, 3974-3984 (2009). | 5821 | 19605557 |
Viral and murine interleukin-10 are correctly processed and retain their biological activity when produced in tobacco. | Bortesi L., Rossato M., Schuster F., Raven N., Stadlmann J., Avesani L., Falorni A., Bazzoni F., Bock R., Schillberg S., Pezzotti M. | BMC Biotechnol., 9: 22 (2009). | 5819 | 19298643 |
Structural basis of the influenza A virus RNA polymerase PB2 RNA-binding domain containing the pathogenicity-determinant lysine 627 residue. | Kuzuhara T., Kise D., Yoshida H., Horita T., Murazaki Y., Nishimura A., Echigo N., Utsunomiya H., Tsuge H. | J. Biol. Chem. 284, 6855-6860 (2009) | 4754 | 19144639 |
Phosphorylation of Activation Transcription Factor-2 at Serine 121 by Protein Kinase C Controls c-Jun-mediated Activation of Transcription. | Yamasaki T., Takahashi A., Pan J., Yamaguchi N., Yokoyama K.K. | J. Biol. Chem., 284, 8567-8581 (2009) | 4753 | 19176525 |
Adenovirus-mediated gene expression of the human c-FLIP(L) gene protects pig islets against human CD8(+) cytotoxic T lymphocyte-mediated cytotoxicity. | Tanemura M., Saga A., Kawamoto K., Machida T., Deguchi T., Nishida T., Sawa Y., Doki Y., Mori M., Ito T. | Transplant. Proc., 41, 319-322 (2009). | 4752 | 19249545 |
Cytosine deaminase-uracil phosphoribosyltransferase and interleukin (IL)-12 and IL-18: a multimodal anticancer interface marked by specific modulation in serum cytokines. | Khatri A., Husaini Y., Ow K., Chapman J., Russell P.J. | Clin. Cancer Res., 15, 2323-2334 (2009). | 4751 | 19318483 |
Usp46 is a quantitative trait gene regulating mouse immobile behavior in the tail suspension and forced swimming tests. | Tomida S., Mamiya T., Sakamaki H., Miura M., Aosaki T., Masuda M., Niwa M., Kameyama T., Kobayashi J., Iwaki Y., Imai S., Ishikawa A., Abe K., Yoshimura T., Nabeshima T., Ebihara S. | Nat. Genet., 41 (6): 688-695 (2009). | 4750 | 19465912 |
Chondromodulin-1 directly suppresses growth of human cancer cells. | Mera H., Kawashima H., Yoshizawa T., Ishibashi O., Ali M.M., Hayami T., Kitahara H., Yamagiwa H., Kondo N., Ogose A., Endo N., Kawashima H. | BMC Cancer, 9, 166 (2009). | 4749 | 19480713 |
Quick method of multimeric protein production for biologically active substances such as human GM-CSF (hGM-CSF). | Shinya E., Owaki A., Norose Y., Sato S., Takahashi H. | Biochem. Biophys. Res. Commun., 386, 40-44 (2009). | 4748 | 19497303 |
Visualization of chemokine receptor activation in transgenic mice reveals peripheral activation of CCR2 receptors in states of neuropathic pain. | Jung H., Bhangoo S., Banisadr G., Freitag C., Ren D., White F.A., Miller R.J. | J. Neurosci., 29, 8051-8062 (2009). | 4747 | 19553445 |
RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway. | Miyake, Y., Nakamura, M., Nabetani, A., Shimamura, S., Tamura, M., Yonehara, S., Saito, M., Ishikawa, F. | Mol. Cell 36 (2):193-206 (2009). | 47433 | 19854130 |
Regulation of exogenous bFGF gene mediated by recombinant adeno-associated virus in vitro | Song, K., Rao, N., Chen, M., Cao, Y. | Frontiers of Medicine in China, 3, 158-163 (2009). | 4600 | |
Thermus thermophilus-derived protein tags that aid in preparation of insoluble viral proteins. | Kondo N., Ebihara A., Ru H., Kuramitsu S., Iwamoto A., Rao Z., Matsuda Z. | Anal. Biochem., 385, 278-285 (2009). | 3801 | 19084492 |
Crystallization and X-ray diffraction analysis of the RNA primer/promoter-binding domain of influenza A virus RNA-dependent RNA polymerase PB2. | Kuzuhara T., Kise D., Yoshida H., Horita T., Murazaki Y., Utsunomiya H., Tsuge H. | Acta Crystallogr. Sect. F. Struct. Biol. Cryst. Commun., 65 (Pt 2): 144-146 (2009). | 3800 | 19194006 |
Mutation I810N in the alpha3 isoform of Na+,K+-ATPase causes impairments in the sodium pump and hyperexcitability in the CNS. | Clapcote, S.J., Duffy, S., Xie, G., Kirshenbaum, G., Bechard, A.R., Rodacker Schack, V., Petersen, J., Sinai, L., Saab, B.J., Lerch, J.P., Minassian, B.A., Ackerley, C.A., Sled, J.G., Cortez, M.A., Henderson, J.T., Vilsen, B., Roder, J.C. | Proc. Natl. Acad. Sci .U S A. 106 (33): 14085-14090 (2009). | 21528 | 19666602 |
Oncolytic gene therapy combined with double suicide genes for human bile duct cancer in nude mouse models. | Kojima, Y., Honda, K., Hamada, H., Kobayashi, N. | J. Surg. Res. 157 (1): e63-70 (2009). | 21523 | 19345377 |
The orphan nuclear receptor RORalpha restrains adipocyte differentiation through a reduction of C/EBPbeta activity and perilipin gene expression. | Ohoka, N., Kato. S., Takahashi. Y., Hayashi, H., Sato, R. | Mol. Endocrinol., 23, 759-771 (2009). | 21513 | 19324970 |
Genetic reconstruction of mouse spermatogonial stem cell self-renewal in vitro by Ras-cyclin D2 activation. | Lee, J., Kanatsu-Shinohara, M., Morimoto, H., Kazuki, Y., Takashima, S., Oshimura, M., Toyokuni, S., Shinohara, T. | Cell Stem. Cell, 5, 76-86 (2009). | 12759 | 19570516 |
Detection and genetic characterisation of qnrB in hospital isolates of Klebsiella pneumoniae in Singapore. | Teo, J.W., Ng, K.Y., Lin, R.T. | Int. J. Antimicrob. Agents., 33, 177-180 (2009). | 12023 | 18993034 |
Transcriptional regulation of fibrillin-2 gene by E2F family members in chondrocyte differentiation. | Yanagino, T., Yuasa, K., Nagahama, M., Matsuda, Y., Tsuji, A. | J. Cell. Biochem. 106 (4): 580-588 (2009). | 12022 | 19142862 |
Abnormal DNA methyltransferase expression in mouse germline stem cells results in spermatogenic defects. | Takashima, S., Takehashi, M., Lee, J., Chuma, S., Okano, M., Hata, K., Suetake, I., Nakatsuji, N., Miyoshi H, Tajima S, Tanaka Y, Toyokuni S, Sasaki, H., Kanatsu-Shinohara, M., Shinohara, T. | Biol. Reprod., 81, 155-164 (2009). | 11972 | 19228594 |
Introduction of tau mutation into cultured Rat1-R12 cells by gene targeting, using recombinant adeno-associated virus vector. | Shimada H., Numazawa K., Sasaki T., Kato N., Ebisawa T. | Cell. Mol. Neurobiol., 29, 699-705 (2009). | 11971 | 19305950 |
Regulation of intestinal Cl-/HCO3- exchanger SLC26A3 by intracellular pH. | Hayashi, H., Suruga, K., Yamashita, Y. | Am. J. Physiol. Cell Physiol., 296, C1279-1290 (2009). | 11970 | 19321737 |
Detection of plasmid-mediated quinolone resistance genes in clinical isolates of Enterobacter spp. in Spain. | Cano M.E., Rodriguez-Martinez J.M., Aguero J., Pascual A., Calvo J., Garcia-Lobo J.M., Velasco C., Francia M.V., Martinez-Martinez L. | J. Clin. Microbiol., 47, 2033-2039 (2009). | 11968 | 19386836 |
Establishment of a cell line derived from a mouse fetal liver that has the characteristic to promote the hepatic maturation of mouse embryonic stem cells by a coculture method. | Fukumitsu K., Ishii T., Yasuchika K., Amagai Y., Kawamura-Saito M., Kawamoto T., Kawase E., Suemori H., Nakatsuji N., Ikai I., Uemoto S. | Tissue Eng. Part A., 15, 3847-3856 (2009). | 11967 | 19558317 |
Selection and growth regulation of genetically modified cells with hapten-specific antibody/receptor tyrosine kinase chimera. | Tanaka, K., Kawahara, M., Ueda, H., Nagamune, T. | Biotechnol. Progr., 25, 1138-1145 (2009). | 11966 | 19569211 |
Green tea catechins inhibit the endonuclease activity of influenza A virus RNA polymerase. | Kuzuhara T., Iwai Y., Takahashi H., Hatakeyama D., Echigo N. | PLoS Curr., 1, RRN1052 (2009). | 11965 | 20025206 |
Construction of a multi-functional helper-dependent adenovirus based system for cancer gene therapy. | Long N., Hardiville S., Pierce A., Fukamachi K., Futakuchi M., Alexander D.B., Shirai T., Tsuda H. | Asian Pac. J. Cancer Prev., 10, 939-960 (2009). | 11964 | 20104994 |
2008
Title | Author | Journal | NBRP RRC ID | PubMed PMID |
---|---|---|---|---|
qnrD, a novel gene conferring transferable quinolone resistance in Salmonella enterica serovar Kentucky and Bovismorbificans strains of human origin. | Cavaco L.M., Hasman H., Xia S., Aarestrup F.M. | Antimicrob. Agents. Chemother., 53, 603-608 (2008). | 6189 | 19029321 |
Epigenetic regulation of neural cell differentiation plasticity in the adult mammalian brain. | Kohyama J., Kojima T., Takatsuka E., Yamashita T., Namiki J., Hsieh J., Gage F.H., Namihira M., Okano H., Sawamoto K., Nakashima K. | Proc. Natl. Acad. Sci. U. S. A., 105, 18012-18017 (2008). | 6188 | 19004774 |
p63/p51-induced onset of keratinocyte differentiation via the c-Jun N-terminal kinase pathway is counteracted by keratinocyte growth factor. | Ogawa E., Okuyama R., Egawa T., Nagoshi H., Obinata M., Tagami H., Ikawa S., Aiba S. | J. Biol. Chem., 283, 34241-34249 (2008). | 6187 | 18849344 |
JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells. | Gurzov E.N., Ortis F., Bakiri L., Wagner E.F, Eizirik,D.L. | PLoS One., 3, e3030 (2008). | 6186 | 18716665 |
Enhancement of cell function through heterotypic cell-cell interactions using E-cadherin-expressing NIH3T3 cells. | Ito A., Kiyohara T., Kawabe Y., Ijima H., Kamihira M. | J. Biosci. Bioeng., 105, 679-682 (2008). | 6185 | 18640611 |
Zfp64 participates in Notch signaling and regulates differentiation in mesenchymal cells. | Sakamoto K., Tamamura Y., Katsube K., Yamaguchi A. | J. Cell Sci., 121, 1613-1623 (2008). | 6184 | 18430783 |
Selective expansion of genetically modified T cells using an antibody/interleukin-2 receptor chimera. | Sogo T., Kawahara M., Tsumoto K., Kumagai I., Ueda H., Nagamune T. | J. Immunol. Methods, 337, 16-23(2008). | 4759 | 18589435 |
Design of the artificial acellular feeder layer for the efficient propagation of mouse embryonic stem cells. | Nagaoka M., Hagiwara Y., Takemura K., Murakami Y., Li J., Duncan S.A., Akaike T. | J. Biol. Chem., 283, 26468-26476 (2008). | 4758 | 18614540 |
Ramified microglial cells promote astrogliogenesis and maintenance of neural stem cells through activation of Stat3 function. | Zhu P., Hata R., Cao F., Gu F., Hanakawa Y., Hashimoto K., Sakanaka M. | FASEB J., 22, 3866-3877 (2008). | 4757 | 18685078 |
Involvement of human ORC and TRF2 in pre-replication complex assembly at telomeres. | Tatsumi Y., Ezura K., Yoshida K., Yugawa T., Narisawa-Saito M., Kiyono T., Ohta S., Obuse C., Fujita M. | Genes Cells, 13, 1045-1059 (2008). | 4756 | 18761675 |
Interaction of KLRG1 with E-cadherin: new functional and structural insights. | Rosshart S., Hofmann M., Schweier O., Pfaff A.K., Yoshimoto K., Takeuchi T., Molnar E., Schamel W.W., Pircher H. | Eur. J. Immunol., 38, 3354-3364 (2008). | 4755 | 19009530 |
Improved tools for efficient mapping of fission yeast genes: identification of microtubule nucleation modifier mod22-1 as an allele of chromatin- remodelling factor gene swr1. | Anders, A., Watt, S., Bahler, J., Sawin, K.E. | Yeast 25 (12): 913-925 (2008). | 47469 | 19160458 |
Monocyte chemoattractant protein-1 functions as a neuromodulator in dorsal root ganglia neurons. | Jung H., Toth P.T., White F.A., Miller R.J. | J. Neurochem., 104, 254-263 (2008). | 3815 | 17944871 |
Interleukin-10 gene transfer to peritoneal mesothelial cells suppresses peritoneal dissemination of gastric cancer cells due to a persistently high concentration in the peritoneal cavity. | Tanaka F., Tominaga K., Shiota M., Ochi M., Kuwamura H., Tanigawa T., Watanabe T., Fujiwara Y., Oshitani N., Higuchi K., Iwao H., Arakawa T. | Cancer Gene Ther., 15, 51-59 (2008). | 3814 | 17992202 |
Identification of angiogenin as the osteoclastic bone resorption-inhibitory factor in bovine milk. | Morita Y., Matsuyama H., Serizawa A., Takeya T., Kawakami H. | Bone, 42, 380-387 (2008). | 3813 | 18055286 |
Characterization of a neuregulin-1 gene promoter: positive regulation of type I isoforms by NF-kappaB. | Frensing T., Kaltschmidt C., Schmitt-John T. | Biochim. Biophys. Acta – Gene Regul. Mech., 1779, 139-144 (2008). | 3812 | 18082154 |
Dimerization-based homogeneous fluorosensor proteins for the detection of specific dsDNA. | Yoshitake K., Waki S., Ueda H. | Biosens. Bioelectron., 23, 1266-1271 (2008). | 3811 | 18178076 |
Plasmid-mediated qepA gene among Escherichia coli clinical isolates from Japan. | Yamane K., Wachino J., Suzuki S., Arakawa Y. | Antimicrob. Agents Chemother., 52, 1564-1566 (2008). | 3810 | 18285488 |
Oocyte-specific overexpression of mouse bone morphogenetic protein-15 leads to accelerated folliculogenesis and an early onset of acyclicity in transgenic mice. | McMahon, H.E., Hashimoto, O., Mellon, P.L., Shimasaki, S. | Endocrinology, 149, 2807-2815 (2008). | 3808 | 18308851 |
Functional evaluation of polymorphisms in the human ABCB1 gene and the impact on clinical responses of antiepileptic drugs. | Hung C.C., Chen C.C., Lin C.J., Liou H.H. | Pharmacogenet. Genomics, 18, 390-402 (2008). | 3807 | 18408562 |
Repair of 2′-C-cyano-2′-deoxy-1-beta-D-arabino-pentofuranosylcytosine-induced DNA single-strand breaks by transcription-coupled nucleotide excision repair. | Wang Y., Liu X., Matsuda A., Plunkett W. | Cancer Res., 68, 3881-3889 (2008). | 3806 | 18483273 |
Covalent split protein fragment-DNA hybrids generated through N-terminus-specific modification of proteins by oligonucleotides. | Takeda S., Tsukiji S., Ueda H., Nagamune T. | Org. Biomol. Chem., 6, 2187-2194 (2008). | 3805 | 18528581 |
Different initial steps of apoptosis induced by two types of antineoplastic drugs. | Takagi Y., Hidaka M., Sanada M., Yoshida H., Sekiguchi M. | Biochem. Pharmacol., 76, 303-311 (2008). | 3804 | 18573489 |
IRF2-binding protein-1 is a JDP2 ubiquitin ligase and an inhibitor of ATF2-dependent transcription. | Kimura M. | FEBS Lett., 582, 2833-2837 (2008). | 3803 | 18671972 |
Phosphorylation of two eukaryotic transcription factors, Jun dimerization protein 2 and activation transcription factor 2, in Escherichia coli by Jun N-terminal kinase 1. | Murata T., Shinozuka Y., Obata Y., Yokoyama K.K. | Anal. Biochem., 376, 115-121 (2008). | 3652 | 18307971 |
Involvement of the estrogen receptor beta in genistein-induced expression of p21(waf1/cip1) in PC-3 prostate cancer cells. | Matsumura, K., Tanaka, T., Kawashima, H., Nakatani, T. | Anticancer Res., 28 (2A): 709-714 (2008). | 30727 | 18507011 |
Expression of transforming growth factor-beta1 and connective tissue growth factor in the capsule in a rat immobilized knee model. | Hagiwara Y., Chimoto E., Takahashi I., Ando A., Sasano Y., Itoi E. | Upsala. J. Med. Sci., 113, 221-234 (2008). | 12026 | 18509817 |
Polyplex micelles with cyclic RGD peptide ligands and disulfide cross-links directing to the enhanced transfection via controlled intracellular trafficking. | Oba M., Aoyagi K., Miyata K., Matsumoto Y., Itaka K., Nishiyama N., Yamasaki Y., Koyama H., Kataoka K. | Mol. Pharm., 5, 1080-1092 (2008). | 12025 | 19434856 |
Homing of mouse spermatogonial stem cells to germline niche depends on beta1-integrin. | Kanatsu-Shinohara, M., Takehashi, M., Takashima, S., Lee, J., Morimoto, H., Chuma, S., Raducanu, A., Nakatsuji, N., Fassler, R., Shinohara, T. | Cell Stem Cell, 3 (5): 533-542 (2008). | 11962 | 18983968 |
Differentiation of mouse hepatic progenitor cells induced by hepatocyte nuclear factor-4 and cell transplantation in mice with liver fibrosis. | Suetsugu A., Nagaki M., Aoki H., Motohashi T., Kunisada T., Moriwaki H. | Transplantation, 86, 1178-1186 (2008). | 11961 | 19005397 |
2007
Title | Author | Journal | NBRP RRC ID | PubMed PMID |
---|---|---|---|---|
First detection of plasmid-mediated quinolone resistance (qnrA and qnrS) in Escherichia coli strains isolated from humans in Scandinavia. | Cavaco L.M., Hansen D.S., Friis-Moller A., Aarestrup F.M., Hasman H., Frimodt-Moller N. | J. Antimicrob. Chemother., 59, 804-805 (2007). | 6198 | 17284539 |
Plasmid-mediated quinolone resistance determinant qnrS1 detected in Salmonella enterica serovar Corvallis strains isolated in Denmark and Thailand. | Cavaco L.M., Hendriksen R.S., Aarestrup F.M. | J. Antimicrob. Chemother., 60, 704-706 (2007). | 6183 | 17635876 |
Cooperation of NF-kappaB2/p100 activation and the PDZ domain binding motif signal in human T-cell leukemia virus type 1 (HTLV-1) Tax1 but not HTLV-2 Tax2 is crucial for interleukin-2-independent growth transformation of a T-cell line. | Higuchi, M., Tsubata, C., Kondo, R., Yoshida, S., Takahashi, M., Oie, M., Tanaka, Y., Mahieux, R., Matsuoka, M., Fujii, M. | J. Virol. 81 (21): 11900-11907 (2007). | 54476 | 17715223 |
Interactions between peptides containing nucleobase amino acids and T7 phages displaying S. cerevisiae proteins. | Watanabe S., Tomizaki K.Y., Takahashi T., Usui K., Kajikawa K., Mihara H. | Biopolymers, 88, 131-140 (2007). | 3824 | 17206624 |
The administration of naked plasmid DNA into the liver induces antitumor innate immunity in a murine liver metastasis model. | Yonenaga Y., Mori A., Fujimoto A., Nagayama S., Tachibana T., Onodera H., Uemoto S. | J. Gene Med., 9, 299-307 (2007). | 3823 | 17397091 |
Identification of genetic networks involved in the cell growth arrest and differentiation of a rat astrocyte cell line RCG-12. | Takasaki I., Takarada S., Fukuchi M., Yasuda M., Tsuda M., Tabuchi Y. | J. Cell. Biochem., 102, 1472-1485 (2007). | 3822 | 17440958 |
E1A, E1B double-restricted adenovirus with RGD-fiber modification exhibits enhanced oncolysis for CAR-deficient biliary cancers. | Wakayama M., Abei M., Kawashima R., Seo E., Fukuda K., Ugai H., Murata T., Tanaka N., Hyodo I., Hamada H., Yokoyama K.K. | Clin. Cancer Res., 13, 3043-3050 (2007). | 3821 | 17505007 |
PIASxbeta is a key regulator of osterix transcriptional activity and matrix mineralization in osteoblasts. | Ali M.M., Yoshizawa T., Ishibashi O., Matsuda A., Ikegame M., Shimomura J., Mera H., Nakashima K., Kawashima H. | J. Cell Sci., 120 (Pt 15), 2565-2573 (2007). | 3820 | 17623776 |
Thrombin-induced cell proliferation and platelet-derived growth factor-AB release from A172 human glioblastoma cells. | Hayakawa Y., Kurimoto M., Nagai, S., Kurosaki K., Tsuboi Y., Hamada H., Hayashi N., Endo S. | J. Thromb. Haemost., 5, 2219-2226 (2007). | 3819 | 17958740 |
Transduction of phosphatase and tensin homolog deleted on chromosome 10 into eosinophils attenuates survival, chemotaxis, and airway inflammation. | Adachi T., Hanaka S., Masuda T., Yoshihara H., Nagase H., Ohta K. | J. Immunol., 179, 8105-8111 (2007). | 3818 | 18056352 |
A dileucine motif in its cytoplasmic domain directs beta-catenin-uncoupled E-cadherin to the lysosome. | Miyashita Y., Ozawa M. | J. Cell Sci., 120, 4395-4406 (2007). | 3817 | 18057030 |
Emergence of complex rearrangements at translocation breakpoints in a transgenic mouse; implications for mechanisms involved in the formation of chromosome rearrangements. | Kasai F., Yoshihara M., Matsukuma S., O’Brien P., Ferguson-Smith M.A. | Cytogenet. Genome Res., 119, 83-90 (2007). | 3816 | 18160786 |
JDP2 suppresses adipocyte differentiation by regulating histone acetylation. | Nakade K., Pan J., Yoshiki A., Ugai H., Kimura M., Liu B., Li H., Obata Y., Iwama M., Itohara S., Murata T., Yokoyama K.K. | Cell Death Differ., 14, 1398-1405 (2007). | 2284 | 17464331 |
Expression of pIX gene induced by transgene promoter: possible cause of host immune response in first-generation adenoviral vectors. | Nakai M., Komiya K., Murata M., Kimura T., Kanaoka M., Kanegae Y., Saito I. | Hum. Gene Ther., 18, 925-936 (2007). | 2283 | 17907966 |
Adipose tissue-specific inactivation of the retinoblastoma protein protects against diabesity because of increased energy expenditure. | Dali-Youcef N., Mataki C., Coste A., Messaddeq N., Giroud S., Blanc S., Koehl C., Champy M.F., Chambon P., Fajas L., Metzger D., Schoonjans K., Auwerx J. | Proc. Natl. Acad. Sci. U S A., 104, 10703-10708 (2007). | 2282 | 17556545 |
Ku70/80 modulates ATM and ATR signaling pathways in response to DNA double strand breaks. | Tomimatsu N., Tahimic C.G., Otsuki A., Burma S., Fukuhara A., Sato K., Shiota G., Oshimura M., Chen D.J., Kurimasa A. | J. Biol. Chem., 282, 10138-10145 (2007). | 2281 | 17272272 |
Notch Ligand Delta-Like 1 Is Essential for Postnatal Arteriogenesis. | Limbourg A., Ploom M., Elligsen D., Sorensen I., Ziegelhoeffer T., Gossler A., Drexler H., Limbourg F.P. | Circ. Res., 100, 363-371 (2007). | 1897 | 17234965 |
Adenovirus-mediated gene delivery into mouse spermatogonial stem cells. | Takehashi, M., Kanatsu-Shinohara, M., Inoue, K., Ogonuki, N., Miki, H., Toyokuni, S, Ogura A., Shinohara, T. | Proc. Natl. Acad. Sci. U. S. A., 104 (8): 2596-2601 (2007). | 12030 | 17299052 |
Strong enhancement of recombinant cytosine deaminase activity in Bifidobacterium longum for tumor-targeting enzyme/prodrug therapy. | Hamaji Y, Fujimori M, Sasaki T, Matsuhashi H, Matsui-Seki K, Shimatani-Shibata Y, Kano Y, Amano Y, Taniguchi S. | Biosci. Biotechnol. Biochem., 71, 874-883 (2007). | 12029 | 17420581 |
Cyclic RGD peptide-conjugated polyplex micelles as a targetable gene delivery system directed to cells possessing alphavbeta3 and alphavbeta5 integrins. | Oba M., Fukushima S., Kanayama N., Aoyagi K., Nishiyama N., Koyama H., Kataoka K. | Bioconjug. Chem., 18, 1415-1423 (2007). | 12028 | 17595054 |
Transcriptional regulation of human eosinophil RNases by an evolutionary- conserved sequence motif in primate genome. | Wang H.Y., Chang H.T., Pai T.W., Wu C.I., Lee Y.H., Chang Y.H., Tai H.L., Tang C.Y., Chou W.Y., Chang M.D. | BMC Mol. Biol., 8:89 (2007). | 12027 | 17927842 |
PTEN reduces cuff-induced neointima formation and proinflammatory cytokines. | Koide, S., Okazaki, M., Tamura, M., Ozumi, K., Takatsu, H., Kamezaki, F., Tanimoto, A., Tasaki, H., Sasaguri, Y., Nakashima, Y., Otsuji, Y. | Am. J. Physiol. Heart Circ. Physiol., 292, 2824-2831 (2007). | 11042 | 17277022 |
PAR1 specifies ciliated cells in vertebrate ectoderm downstream of aPKC. | Ossipova, O., Tabler, J., Green, J.B., Sokol, S.Y. | Development, 134 (23), 4297-4306 (2007). | 11023 | 17993468 |
2006
Title | Author | Journal | NBRP RRC ID | PubMed PMID |
---|---|---|---|---|
Suppression of PTEN expression during aggregation with retinoic acid in P19 mouse embryonal carcinoma cells. | Lee J.H., Shin S.Y., Kim S., Choo J., Lee Y.H. | Biochem. Biophys. Res. Commun., 347, 715-722 (2006). | 6182 | 16842746 |
Suppression of Egr-1 transcription through targeting of the serum response factor by oncogenic H-Ras. | Shin S.Y., Bahk Y.Y., Ko J., Chung I.Y., Lee Y.S., Downward J., Eibel H., Sharma P.M., Olefsky J.M., Kim Y.H., Lee B., Lee Y.H. | EMBO J., 25, 1093-1103 (2006). | 6181 | 16456537 |
E-cadherin-coated plates maintain pluripotent ES cells without colony formation. | Nagaoka M., Koshimizu U., Yuasa S., Hattori F., Chen H., Tanaka T., Okabe M., Fukuda K., Akaike T. | PLoS One, 1, (2006). | 4762 | 17183641 |
Mouse model of human infertility: transient and local inhibition of endometrial STAT-3 activation results in implantation failure. | Nakamura H., Kimura T., Koyama S., Ogita K., Tsutsui T., Shimoya K., Taniguchi T., Koyama M., Kaneda Y., Murata Y. | FEBS Lett., 580, 2717-2722 (2006). | 3888 | 16647058 |
Canonical notch signaling functions as a commitment switch in the epidermal lineage. | Blanpain C., Lowry W.E., Pasolli H.A., Fuchs E. | Gene. Dev., 20, 3022-3035 (2006). | 3887 | 17079689 |
The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development. | Sakaki-Yumoto M., Kobayashi C., Sato A., Fujimura S., Matsumoto Y., Takasato M., Kodama T., Aburatani H., Asashima M., Yoshida N., Nishinakamura R. | Development, 133, 3005-3013 (2006). | 2279 | 16790473 |
Combination gene therapy of HGF and truncated type II TGF-beta receptor for rat liver cirrhosis after partial hepatectomy.† | Ozawa, S., Uchiyama, K., Nakamori, M., Ueda, K., Iwahashi, M., Ueno, H., Muragaki, Y., Ooshima, A., Yamaue, H. | Surgery, 139, 563-573 (2006). | 2278 | 16627068 |
Transgenic mouse for conditional, tissue-specific Cox-2 overexpression | Kamei, K., Ishikawa, T., Herschman, H.R. | Genesis, 44, 177-182 (2006). | 2277 | 16604526 |
Cutting edge: identification of E-cadherin as a ligand for the murine killer cell lectin-like receptor G1. | Grundemann C., Bauer M., Schweier O., von Oppen N., Lassing U., Saudan P., Becker K.F., Karp K., Hanke T., Bachmann M.F., Pircher H. | J. Immunol., 176, 1311-1315 (2006). | 2276 | 16424155 |
CTLA-4Ig suppresses liver injury by inhibiting acquired immune responses in a mouse model of fulminant hepatitis. | Nakayama Y., Shimizu Y., Hirano K., Ebata K., Minemura M., Watanabe A., Sugiyama T. | Hepatology, 42, 915-924 (2006). | 2275 | 16175605 |
Activation of connective tissue growth factor gene by the c-Maf and Lc-Maf transcription factors. | Omoteyama K., Ikeda H., Imaki J., Sakai M. | Biochem. Biophys. Res. Commun., 339, 1089-1097 (2006). | 1905 | 16343439 |
A Novel Yeast-Based Reporter Assay System for the Sensitive Detection of Genotoxic Agents Mediated by a DNA Damage-Inducible LexA-GAL4 Protein. | Ichikawa K., Eki T. | J. Biochem. (Tokyo)., 139, 105-112 (2006). | 1904 | 16428325 |
Regulation of histone acetylation and nucleosome assembly by transcription factor JDP2. | Jin, C., Kato, K., Chimura, T., Yamasaki, T., Nakade, K., Murata, T., Li, H., Pan, J., Zhao, M., Sun, K., Chiu, R., Ito, T., Nagata, K., Horikoshi, M., Yokoyama, K.K. | Nat. Struct. Mol. Biol., 13, 331-338 (2006). | 1902 | 16518400 |
The boosting effect of co-transduction with cytokine genes on cancer vaccine therapy using genetically modified dendritic cells expressing tumor-associated antigen. | Ojima T., Iwahashi M., Nakamura M., Matsuda K., Naka T., Nakamori M., Ueda K., Ishida K., Yamaue H. | Int. J. Oncol., 28, 947-953 (2006). | 1900 | 16525645 |
Ductal origin of pancreatic adenocarcinomas induced by conditional activation of a human Ha-ras oncogene in rat pancreas. | Ueda S., Fukamachi K., Matsuoka Y., Takasuka N., Takeshita F., Naito A., Iigo M., Alexander D.B., Moore M.A., Saito I., Ochiya T., Tsuda H. | Carcinogenesis, 27, 2497-2510 (2006). | 1899 | 16774944 |
Overexpression of SOCS3 inhibits astrogliogenesis and promotes maintenance of neural stem cells | Cao, F., Hata, R., Zhu, P., Ma, Y.J., Tanaka, J., Hanakawa, Y., Hashimoto, K., Niinobe, M., Yoshikawa, K., Sakanaka, M. | J. Neurochem., 98, 459?470 (2006). | 1898 | 16805839 |
Relationship between the P53 functional status of human tumor cell lines and their chemosensitivities to different anticancer drug. | TAN Yajun,LOU Bin,CHEN Yu. | Chin. Edu. Gen. Pract., 4 (2006). | 12039 | |
Defect in serine 46 phosphorylation of p53 contributes to acquisition of p53 resistance in oral squamous cell carcinoma cells. | Ichwan S.J., Yamada S., Sumrejkanchanakij P., Ibrahim-Auerkari E., Eto K., Ikeda M.A. | Oncogene, 25, 1216-1224 (2006). | 12038 | 16247456 |
Lipopolysaccharide-induced microglial activation induces learning and memory deficits without neuronal cell death in rats. | Tanaka S., Ide M., Shibutani T., Ohtaki H., Numazawa S., Shioda S., Yoshida T. | J. Neurosci. Res., 83, 557-566 (2006). | 12037 | 16429444 |
Targeted gene therapy toward astrocytoma using a Cre/loxP-based adenovirus system. | Maeda M., Namikawa K., Kobayashi I., Ohba N., Takahara Y., Kadono C., Tanaka A,, Kiyama H. | Brain Res., 1081, 34-43 (2006). | 12036 | 16529724 |
Src homology 2 (SH2)-containing 5′-inositol phosphatase localizes to podosomes, and the SH2 domain is implicated in the attenuation of bone resorption in osteoclasts. | Yogo K., Mizutamari M., Mishima K., Takenouchi H., Ishida-Kitagawa N., Sasaki T., Takeya T. | Endocrinology, 147, 3307-3317 (2006). | 12035 | 16601135 |
Direct modulation of rheumatoid inflammatory mediator expression in retinoblastoma protein-dependent and -independent pathways by cyclin-dependent kinase 4/6. | Nonomura Y., Nagasaka K., Hagiyama H., Sekine C., Nanki T., Tamamori-Adachi M., Miyasaka N., Kohsaka H. | Arthritis Rheum., 54, 2074-2083 (2006). | 12034 | 16802342 |
Mutation analyses of genes on 6p12-p11 in patients with juvenile myoclonic epilepsy. | Suzuki T., Delgado-Escueta A.V., Alonso M.E., Morita R., Okamura N., Sugimoto Y., Bai D., Medina M.T., Bailey JN, Rasmussen A, Ramos-Peek J, Cordova S, Rubio-Donnadieu F, Ochoa A., Jara-Prado A., Inazawa J., Yamakawa K. | Neurosci. Lett., 405, 126-131 (2006). | 12033 | 16876319 |
Assessment of in vitro applicability of reversibly immortalized NKNT-3 cells and clonal derivatives. | Hoekstra R., Deurholt T., ten Bloemendaal L., Desille M., van Wijk A.C., Clement B., Oude Elferink R.P., van Gulik T.M., Chamuleaut R.A. | Cell Transplant., 15, 423-433 (2006). | 12032 | 16970284 |
Retrovirus-mediated conditional immortalization and analysis of established cell lines of osteoclast precursor cells. | Kawata S., Suzuki J., Maruoka M., Mizutamari M., Ishida-Kitagawa N., Yogo K., Jat P.S., Shishido T. | Biochem. Biophys. Res. Commun., 350, 97-104 (2006). | 12031 | 17005159 |
2005
Title | Author | Journal | NBRP RRC ID | PubMed PMID |
---|---|---|---|---|
Characterization and gene transfer in mesenchymal stem cells derived from human umbilical-cord blood. | Lu F.Z., Fujino M., Kitazawa Y., Uyama T., Hara Y., Funeshima N., Jiang J.Y., Umezawa A., Li X.K. | J. Lab. Clin. Med., 146, 271-278 (2005). | 4763 | 16242526 |
Gene expression profiling of cathepsin D, metallothioneins-1 and -2, osteopontin, and tenascin-C in a mouse spinal cord injury model by cDNA microarray analysis. | Hashimoto M., Koda M., Ino H., Yoshinaga K., Murata A., Yamazaki M., Kojima K., Chiba K., Mori C., Moriya H. | Acta Neuropathol., 109, 165-180 (2005). | 3910 | 15592854 |
Overexpression of granulocyte-macrophage colony-stimulating factor in mouse liver enhances the susceptibility of lipopolysaccharide leading to massive apoptosis of hepatocytes | Hirano, K., Shimizu, Y., Nakayama, Y., Minemura, M., Yasumura, S., Sugiyama, T. | Liver Int., 25, 1027-1035 (2005). | 2274 | 16162163 |
Gene therapy for hepatocellular carcinoma using sonoporation enhanced by contrast agents | Sakakima Y., Hayashi S., Yagi Y., Hayakawa A., Tachibana K., Nakao A. | Cancer Gene Ther., 12, 884-889 (2005). | 2273 | 15891773 |
G alpha 12/13- and reactive oxygen species-dependent activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase by angiotensin receptor stimulation in rat neonatal cardiomyocytes. | Nishida M., Tanabe S., Maruyama Y., Mangmool S., Urayama K., Nagamatsu Y., Takagahara S., Turner J.H., Kozasa T., Kobayashi H., Sato Y., Kawanishi T., Inoue R., Nagao T., Kurose H. | J. Biol. Chem., 280, 18434-18441 (2005). | 2016 | 15743761 |
Galpha12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts. | Fujii T., Onohara N., Maruyama Y., Tanabe S., Kobayashi H., Fukutomi M., Nagamatsu Y., Nishihara N., Inoue R., Sumimoto H., Shibasaki F., Nagao T., Nishida M., Kurose H. | J. Biol. Chem., 280, 23041-23047 (2005). | 2015 | 15826947 |
C/EBPalpha functionally and physically interacts with GABP to activate the human myeloid IgA Fc receptor (Fc alphaR, CD89) gene promoter. | Shimokawa T., Ra C. | Blood, 106, 2534-2542 (2005). | 2014 | 15928042 |
Suppression of Stat3 promotes neurogenesis in cultured neural stem cells. | Gu F., Hata R., Ma Y.J., Tanaka J., Mitsuda N., Kumon Y., Hanakawa Y., Hashimoto K., Nakajima K., Sakanaka M. | J. Neurosci. Res., 81, 163-171 (2005). | 2013 | 15948155 |
Impaired nuclear translocation of CAR in hepatic preneoplastic lesions: association with an attenuated CYP2B induction by phenobarbital. | Numazawa S., Shindo S., Maruyama K., Chibana F., Kawahara Y., Ashino T., Tanaka S., Yoshida T. | FEBS Lett., 579, 3560-3564 (2005). | 2012 | 15953603 |
Light-induced gene transfer from packaged DNA enveloped in a dendrimeric photosensitizer. | Nishiyama N., Iriyama A., Jang W.D., Miyata K., Itaka K., Inoue Y., Takahashi H., Yanagi Y., Tamaki Y., Koyama H., Kataoka K. | Nat. Mater., 4, 934-941 (2005). | 2010 | 16299510 |
Distinct roles of EGF repeats for the Notch signaling system. | Sakamoto K., Chao W.S., Katsube K., Yamaguchi A. | Exp. Cell Res., 302, 281-291 (2005). | 1614 | 15561108 |
Delection of the PDGFR-beta Gene Affects Key Fibroblast Functions Important for Wound Healing | Gao Z., Sasaoka T., Fujimori T., Oya T., Ishii Y., Sabit H., Kawaguchi M., Kurotaki Y., Naito M., Wada T., Ishizawa S., Kobayashi M., Nabeshima Y., Sasahara M. | J. Biol. Chem., 280, 9375-9389 (2005). | 1613 | 15590688 |
Functional characterization of a conditionally immortalized mouse epididymis caput epithelial cell line MEPC5 using temperature-sensitive simian virus 40 large T-antigen. | Tabuchi Y, Toyama Y, Toshimori K, Komiyama M, Mori C, Kondo T. | Biochem. Biophys. Res. Commun., 329, 812-823 (2005). | 1611 | 15752729 |
Interference with the IL-1-signaling pathway improves the toxicity profile of systemically applied adenovirus vectors. | Shayakhmetov D.M., Li Z.Y., Ni S., Lieber A. | J. Immunol., 174, 7310-7319 (2005). | 1609 | 15905578 |
A database of recombinant viruses and recombinant viral vectors available from the RIKEN DNA bank. | Ugai H., Murata T., Nagamura Y., Ugawa Y., Suzuki E., Nakata H., Kujime Y., Inamoto S., Hirose M., Inabe K., Terashima M., Yamasaki T., Liu B., Nakade K., Pan J., Kimura M., Saito I., Hamada H., Obata Y., Yokoyama K.K. | J. Gene Med., 7, 1148-1157 (2005). | 1607 | 15945121 |
Akt/protein kinase B-dependent phosphorylation and inactivation of WEE1Hu promote cell cycle progression at G2/M transition. | Katayama K., Fujita N., Tsuruo T. | Mol. Cell. Biol., 25, 5725-5737 (2005). | 1606 | 15964826 |
Adenovirus-mediated p53 gene transfer to the bile duct by direct administration into the bile in a rat cholangitis model. | Kojima Y., Honda K., Kotegawa H., Kushihata F., Kobayashi N., Liu B., Yokoyama K.K. | J. Surg. Res., 128, 126-131 (2005). | 1605 | 16005898 |
Adenovirus-mediated gene delivery of interleukin-10, but not transforming growth factor beta, ameliorates the induction of Graves’ hyperthyroidism in BALB/c mice. | Saitoh O., Mizutori Y., Takamura N., Yamasaki H., Kita A., Kuwahara H., Nagayama Y. | Clin. Exp. Immunol., 141, 405-411 (2005). | 1604 | 16045729 |
Ribozymes targeting serine/threonine kinase Akt1 sensitize cells to anticancer drugs. | Yanagihara M., Katano M., Takahashi-Sasaki N., Kimata K., Taira K., Andoh T. | Cancer Sci., 96, 620-6 (2005). | 1603 | 16128748 |
Effective gene therapy of biliary tract cancers by a conditionally replicative adenovirus expressing uracil phosphoribosyltransferase: significance of timing of 5-fluorouracil administration. | Seo E., Abei M., Wakayama M., Fukuda K., Ugai H., Murata T., Todoroki T., Matsuzaki Y., Tanaka N., Hamada H., Yokoyama K.K. | Cancer Res., 65, 546-552 (2005). | 1528 | 15695398 |
Secretory phospholipases A2 induce neurite outgrowth in PC12 cells through lysophosphatidylcholine generation and activation of G2A receptor. | Ikeno Y., Konno N., Cheon S.H., Bolchi A., Ottonello S., Kitamoto K., Arioka M. | J. Biol. Chem., 280, 28044-28052, (2005). | 1479 | 15927955 |
Identification of HIV-1 epitopes that induce the synthesis of a R5 HIV-1 suppression factor by human CD4+ T cells isolated from HIV-1 immunized hu-PBL SCID mice. | Yoshida A., Tanaka R., Kodama A., Yamamoto N., Ansari A.A., Tanaka Y. | Clin. Dev. Immunol., 12, 235-242 (2005). | 12700 | 16584108 |
Physical and functional association of c-Src and adhesion and degranulation promoting adaptor protein (ADAP) in osteoclastogenesis in vitro. | Koga S., Yogo K., Yoshikawa K., Samori H., Goto M., Uchida T., Ishida N., Takeya T. | J. Biol. Chem., 280, 31564-31571 (2005). | 12044 | 16020549 |
Adenovirus-mediated expression of heparin cofactor II inhibits thrombin-induced cellular responses in fibroblasts and vascular smooth muscle cells. | Hayakawa Y., Hirashima Y., Yamamoto H., Hayashi N., Kurimoto M., Kuwayama N., Endo S. | Thromb. Res., 116, 357-363 (2005). | 12043 | 16038721 |
Downregulation of cyclin-dependent kinase inhibitor; p57(kip2), is involved in the cell cycle progression of vascular smooth muscle cell. | Nakano, N., Urasawa, K., Takagi, Y., Saito, T., Kaneta, S., Ishikawa, S., Higashi, H., Tsutsui, H., Hatakeyama, M., Kitabatake, A. | Biochem. Biophys. Res. Commun., 338, 1661-1667 (2005). | 12042 | 16259944 |
Homologues of the Caenorhabditis elegans Fox-1 protein are neuronal splicing regulators in mammals. | Underwood, J.G., Boutz, P.L., Dougherty, J.D., Stoilov, P., Black, D.L. | Mol. Cell. Biol., 25 (22), 10005-10016 (2005). | 12041 | 16260614 |
Conditional MN1-TEL knock-in mice develop acute myeloid leukemia in conjunction with overexpression of HOXA9. | Kawagoe, H., Grosveld, G.C. | Blood 106 (13): 4269-4277 (2005). | 11033 | 16105979 |
Accumulation of infectious mutants in stocks during the propagation of fiber-modified recombinant adenoviruses. | Ugai H., Inabe K., Yamasaki T., Murata T., Obata Y., Hamada H., Yokoyama K.K. | Biochem. Biophys. Res. Commun. 337, 806-814 (2005). | 16214112 |
2004
Title | Author | Journal | NBRP RRC ID | PubMed PMID |
---|---|---|---|---|
Adenovirus-mediated p53 gene transfer to the biliary tract in a rat cholangitis model. | Kojima Y., Honda K., Yokoyama K.K, Kushihata F., Kobayashi N. | J. Japan Biliary Assoc., 18, 174-181 (2004). | 2018 | |
Immature dendritic cells reduce proinflammatory cytokine production by a coculture of macrophages and apoptotic cells in a cell-to-cell contact-dependent manner. | Takahashi M., Kurosaka K., Kobayashi Y. | J. Leukoc. Biol., 75, 865-873 (2004). | 2017 | 14761936 |
Stress induces mitochondria-mediated apoptosis independent of SAPK/JNK activation in embryonic stem cells. | Nishitai G., Shimizu N., Negishi T., Kishimoto H., Nakagawa K., Kitagawa D., Watanabe T., Momose H., Ohata S., Tanemura S., Asaka S., Kubota J., Saito R., Yoshida H., Mak T.W., Wada T., Penninger J.M., Azuma N., Nishina H., Katada T. | J. Biol. Chem., 279, 1621-1626 (2004). | 1599 | 14585831 |
S100A1 is a novel molecular chaperone and a member of the Hsp70/Hsp90 multichaperone complex. | Okada M., Hatakeyama T., Itoh H., Tokuta N., Tokumitsu H., Kobayashi R. | J. Biol. Chem., 279, 4221-4233 (2004). | 1598 | 14638689 |
A simple method for the simultaneous detection of E1A and E1B in adenovirus stocks. | Suzuki E., Murata T., Watanabe S., Kujime Y., Hirose M., Pan J., Yamazaki T., Ugai H., Yokoyama K.K. | Oncol. Rep., 11, 173-178 (2004). | 1597 | 14654922 |
Xenopus death receptor-M1 and -M2, new members of the tumor necrosis factor receptor superfamily, trigger apoptotic signaling by differential mechanisms. | Tamura K., Noyama T., Ishizawa YH., Takamatsu N., Shiba T., Ito M. | J. Biol. Chem., 279, 7629-7635 (2004) | 1596 | 14668340 |
Model of unidirectional transluminal gene transfer. | Arap MA, Lahdenranta J, Hajitou A, Marini FC 3rd, Wood CG, Wright KC, Fueyo J, Arap W, Pasqualini R. | Mol. Ther., 9, 305-310 (2004). | 1595 | 14759814 |
Identification of a POU factor involved in regulating the neuron-specific expression of the gene encoding diapause hormone and pheromone biosynthesis-activating neuropeptide in Bombyx mori. | Zhang T.Y., Kang L., Zhang Z.F., Xu W.H. | Biochem. J., 380, 255-263 (2004). | 1594 | 14766018 |
Gene therapy eradicating distant disseminated micro-metastases by optimal cytokine expression in the primary lesion only: novel concepts for successful cytokine gene therapy. | Nagano S., Yuge K., Fukunaga M., Terazaki Y., Fujiwara H., Komiya S., Kosai K. | Int. J. Oncol., 24, 549-558 (2004). | 1593 | 14767539 |
Separate control of Rep and Cap expression using mutant and wild-type loxP sequences and improved packaging system for adeno-associated virus vector production. | Mizukami H., Okada T., Ogasawara Y., Matsushita T., Urabe M., Kume A., Ozawa K. | Mol. Biotechnol., 27, 7-14 (2004). | 1591 | 15122043 |
Dendritic cell vaccine therapy by immunization with fusion cells of interleukin-2 gene-transduced, spleen-derived dendritic cells and tumour cells. | Ogawa F., Iinuma H., Okinaga K. | Scand. J. Immunol., 59, 432-439 (2004). | 1590 | 15140052 |
Cell specificity and efficiency of the Semliki forest virus vector- and adenovirus vector-mediated gene expression in mouse cerebellum. | Sato Y., Shiraishi Y., Furuichi T. | J. Neurosci. Methods, 137, 111-121 (2004). | 1589 | 15196833 |
Development of donor-specific immunoregulatory T-cells after local CTLA4Ig gene transfer to pancreatic allograft. | Miao G., Ito T., Uchikoshi F., Akamaru Y., Kiyomoto T., Komodo H., Song J., Nozawa M., Matsuda H. | Transplantation, 78, 59-64 (2004). | 1588 | 15257039 |
Genes for systemic vascular complications are differentially expressed in the livers of type 2 diabetic patients. | Takamura T., Sakurai M., Ota T., Ando H., Honda M., Kaneko S. | Diabetologia, 47, 638-647 (2004). | 1587 | 15298340 |
Reciprocal signaling between the transcriptional co-factor Eya2 and specific members of the Galphai family. | Embry A.C., Glick J.L., Linder M.E., Casey P.J. | Mol. Pharmacol., 66, 1325-1331 (2004). | 1586 | 15308761 |
Alteration of the timing of implantation by in vivo gene transfer: delay of implantation by suppression of nuclear factor kappaB activity and partial rescue by leukemia inhibitory factor. | Nakamura H., Kimura T., Ogita K., Koyama S., Tsujie T., Tsutsui T., Shimoya K., Koyama M., Kaneda Y., Murata Y. | Biochem. Biophys. Res. Commun., 321, 886-892 (2004). | 1585 | 15358109 |
Cardiomyocytes fuse with surrounding noncardiomyocytes and reenter the cell cycle. | Matsuura K., Wada H., Nagai T., Iijima Y., Minamino T., Sano M., Akazawa H., Molkentin J.D., Kasanuki H., Komuro I. | J. Cell Biol., 167, 351-363 (2004). | 1584 | 15492039 |
Adeno-associated virus vector-mediated interleukin-10 gene transfer inhibits atherosclerosis in apolipoprotein E-deficient mice. | Yoshioka T., Okada T., Maeda Y., Ikeda U., Shimpo M., Nomoto T., Takeuchi K., Nonaka-Sarukawa M., Ito T., Takahashi M., Matsushita T., Mizukami H., Hanazono Y., Kume A., Ookawara S., Kawano M., Ishibashi S., Shimada K., Ozawa K. | Gene Ther., 11, 1772-1779 (2004). | 1583 | 15496963 |
An antigen-mediated selection system for mammalian cells that produce glycosylated single-chain Fv. | Pihkala P., Kawahara M., Ueda H., Nagamune T. | Biochem. Biophys. Res. Commun., 324, 1165-1172 (2004). | 1582 | 15504336 |
Induction of mouse c-src in RAW264 cells is dependent on AP-1 and NF-kappaB and important for progression to multinucleated cell formation. | Kumagai N., Ohno K., Tameshige R., Hoshijima M., Yogo K., Ishida N., Takeya T. | Biochem. Biophys. Res. Commun., 325, 758-768 (2004). | 1581 | 15541355 |
Production of soluble mammalian proteins in Escherichia coli: identification of protein features that correlate with successful expression | Dyson M.R., Shadbolt S.P., Vincent K.J., Perera R.L., McCafferty J. | BMC Biotechnol., 4, 1-18 (2004). | 1580 | 15598350 |
Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation. | Ikeda F., Nishimura R., Matsubara T., Tanaka S., Inoue J., Reddy S.V., Hata K., Yamashita K., Hiraga T., Watanabe T., Kukita T., Yoshioka K., Rao A., Yoneda T. | J. Clin. Invest., 114, 475-484 (2004). | 1377 | 15314684 |
Angiogenic endothelium-specific nestin expression is enhanced by the first intron of the nestin gene. | Aihara M., Sugawara K., Torii S., Hosaka M., Kurihara H., Saito N., Takeuchi T. | Lab. Invest., 84, 1581-1592 (2004). | 1370 | 15502861 |
Altered expression of antiviral cytokine mRNAs associated with cyclophosphamide’s enhancement of viral oncolysis. | Wakimoto H., Fulci G., Tyminski E., Chiocca E.A. | Gene. Ther., 11, 214-223 (2004). | 12740 | 14712306 |
Quercetin enhances melanogenesis by increasing the activity and synthesis of tyrosinase in human melanoma cells and in normal human melanocytes. | Nagata, H., Takekoshi, S., Takeyama, R., Homma, T., Osamura, R.Y. | Pigment Cell Res. 17, 66-73 (2004). | 12052 | 14717847 |
A method for oral DNA delivery with N-acetylated chitosan. | Kai E., Ochiya T. | Pharm. Res., 21, 838-843 (2004). | 12051 | 15180343 |
Effects of the phytoestrogen coumestrol on RANK-ligand-induced differentiation of osteoclasts. | Kanno S., Hirano S., Kayama F. | Toxicology., 203, 211-220 (2004). | 12049 | 15363596 |
Functional activity of human hepatoma cells transfected with adenovirus-mediated hepatocyte nuclear factor (HNF)-4 gene. | Naiki T., Nagaki M., Shidoji Y., Kojima H., Moriwaki H. | Cell Transplant., 13, 393-403 (2004). | 12048 | 15468681 |
2003
Title | Author | Journal | NBRP RRC ID | PubMed PMID |
---|---|---|---|---|
Spontaneous mutations in the human gene for p53 in recombinant adenovirus during multiple passages in human embryonic kidney 293 cells. | Ugai H., Suzuki E., Inabe K., Murata T., Hamada H., Yokoyama K.K. | Biochem. Biophys. Res. Commun., 300, 448-456. (2003). | 2042 | 12504105 |
Reduction of Natural Adenovirus Tropism to the Liver by both Ablation of Fiber-Coxsackievirus and Adenovirus Receptor Interaction and Use of Replaceable Short Fiber. | Nakamura T., Sato K., Hamada H. | J. Virol., 77, 2512-2521 (2003). | 2041 | 12551989 |
Differential Requirement of G{alpha}12, G{alpha}13, G{alpha}q, and G{beta gamma} for Endothelin-1-Induced c-Jun NH2-Terminal Kinase and Extracellular Signal-Regulated Kinase Activation. | Arai K., Maruyama Y., Nishida M., Tanabe S., Takagahara S., Kozasa T., Mori Y., Nagao T., Kurose H. | Mol. Pharmacol., 63, 478-488 (2003). | 2040 | 12606754 |
Prevention of autoantibody-mediated Graves’-like hyperthyroidism in mice with IL-4, a Th2 cytokine. | Nagayama Y., Mizuguchi H., Hayakawa T., Niwa M., McLachlan S.M., Rapoport B. | J. Immunol., 170, 3522-3527 (2003). | 2039 | 12646613 |
Recombinant adenovirus vector bearing antisense macrophage migration inhibitory factor cDNA prevents acute lipopolysaccharide-induced liver failure in mice. | Iwaki T., Sugimura M., Nishihira J., Matsuura T., Kobayashi T., Kanayama N. | Lab. Invest., 83, 561-570 (2003). | 2037 | 12695559 |
Transgenic expression of a dominant-negative connexin26 causes degeneration of the organ of Corti and non-syndromic deafness. | Kudo T., Kure S., Ikeda K., Xia A.P., Katori Y., Suzuki M., Kojima K., Ichinohe A., Suzuki Y., Aoki Y., Kobayashi T., Matsubara Y. | Hum. Mol. Genet., 12, 995-1004 (2003). | 2036 | 12700168 |
Adenovirus-mediated gene transfer of interferon alpha improves dimethylnitrosamine-induced liver cirrhosis in rat model. | Suzuki K., Aoki K., Ohnami S., Yoshida K., Kazui T., Kato N., Inoue K., Kohara M., Yoshida T. | Gene Ther., 10, 765-773 (2003). | 2035 | 12704415 |
Potential tumor suppressive pathway involving DUSP6/MKP-3 in pancreatic cancer. | Furukawa T., Sunamura M., Motoi F., Matsuno S., Horii A. | Am. J. Pathol., 162, 1807-1815 (2003). | 2032 | 12759238 |
Insight into antibody responses induced by plasmid or adenoviral vectors encoding thyroid peroxidase, a major thyroid autoantigen. | Guo J., Pichurin P., Nagayama Y., Rapoport B., McLachlan S.M. | Clin. Exp. Immunol., 132, 408-415 (2003). | 2031 | 12780686 |
Human MDR1 polymorphism: G2677T/A and C3435T have no effect on MDR1 transport activities. | Morita N., Yasumori T., Nakayama K. | Biochem. Pharmacol., 65, 1843-1852 (2003). | 2030 | 12781336 |
Hsp90 is a direct target of the anti-allergic drugs disodium cromoglycate and amlexanox. | Okada M., Itoh H., Hatakeyama T., Tokumitsu H., Kobayashi R. | Biochem. J., 374, 433-441 (2003). | 2029 | 12803546 |
Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation. | Furuyama T., Kitayama K., Yamashita H., Mori N. | Biochem. J., 375, 365-371 (2003). | 2028 | 12820900 |
Effect of an adenoviral vector that expresses the canine p53 gene on cell growth of canine osteosarcoma and mammary adenocarcinoma cell lines. | Yazawa M., Setoguchi A., Hong S.H., Uyama R., Nakagawa T., Kanaya N., Nishimura R., Sasaki N., Masuda K., Ohno K., Tsujimoto H. | Am. J. Vet. Res., 64, 880-888 (2003). | 2027 | 12856773 |
Adenoviral interleukin-12 gene transduction into human bronchial epithelial cells: up-regulation of pro-inflammatory cytokines and its prevention by corticosteroids. | Ogawa H., Nishimura N., Nishioka Y., Azuma M., Yanagawa H., Sone S. | Clin. Exp. Allergy., 33, 921-929 (2003). | 2026 | 12859448 |
E1A, E1B double-restricted adenovirus for oncolytic gene therapy of gallbladder cancer. | Fukuda K., Abei M., Ugai H., Seo E., Wakayama M., Murata T., Todoroki T., Tanaka N., Hamada H., Yokoyama K.K. | Cancer Res., 63, 4434-4440 (2003). | 2025 | 12907616 |
Immortalization of bone marrow-derived human mesenchymal stem cells by removable simian virus 40T antigen gene: analysis of the ability to support expansion of cord blood hematopoietic progenitor cells. | Nishioka K., Fujimori Y., Hashimoto-Tamaoki T., Kai S., Qiu H., Kobayashi N., Tanaka N., Westerman K.A, Leboulch P., Hara H. | Int. J. Oncol., 23, 925-32 (2003). | 2024 | 12963970 |
Involvement of fatty acid pathways and cortical interaction of the pronuclear complex in Caenorhabditis elegans embryonic polarity. | Nonomura Y., Kohsaka H., Nagasaka K., Miyasaka N. | BMC Dev. Biol., 3, 8 (2003). | 2023 | 14527340 |
Gene transfer of a cell cycle modulator exerts anti-inflammatory effects in the treatment of arthritis. | Nonomura Y., Kohsaka H., Nagasaka K., Miyasaka N. | J. Immunol., 171, 4913-4919 (2003). | 2022 | 14568973 |
Inducible liver injury in the transgenic rat by expressing liver-specific suicide gene. | Kawasaki M., Fujino M., Li X.K., Kitazawa Y., Funeshima N., Takahashi R., Ueda M., Amano T., Hakamata Y., Kobayashi E. | Biochem. Biophys. Res. Commun., 311, 920-928 (2003). | 2021 | 14623269 |
Effects of rhinovirus infection on the adherence of Streptococcus pneumoniae to cultured human rirway epithelial cells. | Ishizuka S., Yamaya M., Suzuki T., Takahashi H., Ida S., Sasaki T., Inoue D., Sekizawa K., Nishimura H., Sasaki H. | J. Infect. Dis., 188, 1928-1939 (2003). | 2020 | 14673774 |
Thyroid cancer immuno-therapy with retroviral and adenoviral vectors expressing granulocyte macrophage colony stimulating factor and interleukin-12 in a rat model. | Tanaka K., Towata S., Nakao K., Mizuguchi H., Hayakawa T., Niwa M., Ishii N., Nagayama Y. | Clin. Endocrinol., 59, 734-742 (2003). | 2019 | 14974915 |
Region-specific and epileptogenic-dependent expression of six subtypes of alpha2,3-sialyltransferase in the adult mouse brain. | Matsuhashi H., Horii Y., Kato K. | J. Neurochem., 84, 53-66 (2003). | 12057 | 12485401 |
Ex vivo and systemic transfer of adenovirus-mediated CTLA4Ig gene combined with a short course of FK506 therapy prolongs islet graft survival. | Akamaru Y., Ito T., Uchikoshi F., Maeda A., Tori M., Kiyomoto T., Komoda H., Miao G., Matsuda H. | Transpl. Immunol., 11, 91-100 (2003). | 12056 | 12727480 |
Induction of protective immune responses against R5 human immunodeficiency virus type 1 (HIV-1) infection in hu-PBL-SCID mice by intrasplenic immunization with HIV-1-pulsed dendritic cells: possible involvement of a novel factor of human CD4(+) T-cell origin. | Yoshida A., Tanaka R., Murakami T., Takahashi Y., Koyanagi Y., Nakamura M., Ito M., Yamamoto N., Tanaka Y. | J. Virol., 77, 8719-8728 (2003). | 12055 | 12885891 |
Roles of MGMT and MLH1 proteins in alkylation-induced apoptosis and mutagenesis. | Takagi Y., Takahashi M., Sanada M., Ito R., Yamaizumi M., Sekiguchi M. | DNA Repair (Amst)., 2, 1135-1146 (2003). | 12054 | 13679151 |
Inhibition by dexamethasone of interleukin 13 production via glucocorticoid receptor-mediated inhibition of c-Jun phosphorylation. | Hirasawa N., Izumi S., Linwong W., Ohuchi K. | FEBS Lett., 554, 489-493 (2003). | 12053 | 14623117 |
2002
Title | Author | Journal | NBRP RRC ID | PubMed PMID |
---|---|---|---|---|
Controlled expansion of human endothelial cell populations by Cre-loxP-based reversible immortalization. | Noguchi H., Kobayashi N., Westerman K.A., Sakaguchi M., Okitsu T., Totsugawa T., Watanabe T., Matsumura T., Fujiwara T., Ueda T., Miyazaki M., Tanaka N., Leboulch P. | Hum. Gene Ther., 13, 321-334 (2002). | 4767 | 11812287 |
Adenovirus-mediated gene delivery and in vitro microinsemination produce offspring from infertile male mice. | Kanatsu-Shinohara M., Ogura A., Ikegawa M., Inoue K., Ogonuki N., Tashiro K., Toyokuni S., Honjo T., Shinohara T. | Proc. Natl. Acad. Sci. U. S. A., 99, 1383-1388 (2002). | 2061 | 11818536 |
A novel murine model of Graves’ hyperthyroidism with intramuscular injection of adenovirus expressing the thyrotropin receptor. | Nagayama Y., Kita-Furuyama M., Ando T., Nakao K., Mizuguchi H., Hayakawa T., Eguchi K., Niwa M. | J. Immunol., 168, 2789-2794 (2002). | 2060 | 11884447 |
Enhanced antitumor effect and reduced vector dissemination with fiber-modified adenovirus vectors expressing herpes simplex virus thymidine kinase. | Mizuguchi H., Hayakawa T. | Cancer Gene Ther., 9, 236-242 (2002). | 2059 | 11896439 |
Interleukin (IL)-12 gene transduction and expression into human bronchial epithelial cells (BEAS-2B) by adenovirus vector. | Ogawa H., Nishimura N., Nishioka Y., Azuma M., Yanagawa H., Sone S. | J. Med. Invest., 49, 74-82 (2002). | 2058 | 11901765 |
Characterization of caspase-8L: a novel isoform of caspase-8 that behaves as an inhibitor of the caspase cascade. | Himeji D., Horiuchi T., Tsukamoto H., Hayashi K., Watanabe T., Harada M. | Blood, 99, 4070-4078 (2002). | 2057 | 12010809 |
TGFbeta3-induced activation of RhoA/Rho-kinase pathway is necessary but not sufficient for epithelio-mesenchymal transdifferentiation: implications for palatogenesis. | Kaartinen V., Haataja L., Nagy A., Heisterkamp N., Groffen J. | Int. J. Mol. Med., 9, 563-70 (2002). | 2056 | 12011971 |
Stability of a Recombinant Adenoviral Vector: Optimization of Conditions for Storage, Transport and Delivery | Ugai H., Watanabe S., Suzuki E., Tsutsui-Nakata H., Yokoyama K., Murata T. | Jpn. J. Cancer Res., 93, 598-603 (2002). | 2055 | 12036457 |
Over-expression of PAR-3 suppresses contact-mediated inhibition of cell migration in MDCK cells. | Mishima A., Suzuki A., Enaka M., Hirose T., Mizuno K., Ohnishi T., Mohri H., Ishigatsubo Y., Ohno S. | Genes Cells., 7, 581-596 (2002). | 2054 | 12059961 |
aPKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarization. | Suzuki A., Ishiyama C., Hashiba K., Shimizu M., Ebnet K., Ohno S. | J. Cell Sci., 115, 3565-3573 (2002). | 2052 | 12186943 |
Differential expression of multiple isoforms of the ELKS mRNAs involved in a papillary thyroid carcinoma. | Nakata T., Yokota T., Emi M., Minami S. | Gene. Chromosome. Canc., 35, 30-37 (2002). | 2051 | 12203787 |
MAPK-upstream protein kinase (MUK) regulates the radial migration of immature neurons in telencephalon of mouse embryo. | Hirai S., Kawaguchi A., Hirasawa R., Baba M., Ohnishi T., Ohno S. | Development, 129, 4483-4495 (2002). | 2050 | 12223406 |
Developmental alteration of nerve injury induced glial cell line-derived neurotrophic factor (GDNF) receptor expression is crucial for the determination of injured motoneuron fate. | Honma M., Namikawa K., Mansur K., Iwata T., Mori N., Iizuka H., Kiyama H. | J. Neurochem., 82, 961-975 (2002). | 2049 | 12358802 |
Regulated protein-protein interaction between aPKC and PAR-3 plays an essential role in the polarization of epithelial cells. | Nagai-Tamai Y., Mizuno K., Hirose T., Suzuki A., Ohno S. | Genes Cells, 7, 1161-1171 (2002). | 2048 | 12390250 |
Galpha(12/13) mediates alpha(1)-adrenergic receptor-induced cardiac hypertrophy. | Maruyama Y., Nishida M., Sugimoto Y., Tanabe S., Turner J.H., Kozasa T., Wada T., Nagao T., Kurose H. | Circ. Res., 91, 961-969 (2002). | 2047 | 12433842 |
A homogeneous and noncompetitive immunoassay based on the enhanced fluorescence resonance energy transfer by leucine zipper interaction. | Ohiro Y., Arai R., Ueda H., Nagamune T. | Anal. Chem., 74, 5786-5792 (2002). | 2046 | 12463362 |
Immobilized E-cadherin model can enhance cell attachment and differentiation of primary hepatocytes but not proliferation. | Nagaoka M., Ise H., Akaike T. | Biotechnol. Lett., 24, 1857-1862 (2002). | 1555 | |
Analysis of gene expression profile induced by hepatocyte nuclear factor 4alpha in hepatoma cells using an oligonucleotide microarray. | Naiki T., Nagaki M., Shidoji Y., Kojima H., Imose M., Kato T., Ohishi N., Yagi K., Moriwaki H. | J. Biol. Chem., 277, 14011-14019(2002). | 12065 | 11834723 |
Stimulation of catecholamine biosynthesis via the protein kinase C pathway by endothelin-1 in PC12 rat pheochromocytoma cells. | Takekoshi K., Ishii K., Shibuya S., Kawakami Y., Isobe K., Nakai T. | Biochem. Pharmacol., 63, 977-984 (2002). | 12064 | 11911850 |
Cytoplasmic RNA vector derived from nontransmissible Sendai virus. Production and use. | Iida A., Hasegawa M. | Methods Mol. Med., 69, 361-370 (2002). | 12063 | 11987789 |
Transepithelial transport and cellular accumulation of steroid hormones and polychlorobiphenyl in porcine kidney cells expressed with human P-glycoprotein. | Fujise H., Annoura T., Sasawatari S., Ikeda T., Ueda K. | Chemosphere., 46, 1505-1511 (2002). | 12062 | 12002483 |
Interleukin-12-gene transduction makes DCs from tumor-bearing mice an effective inducer of tumor-specific immunity in a peritoneal dissemination model. | Furumoto K., Mori A., Yamasaki S., Inoue N., Yang W., Nakau M., Yasuda S., Arii S., Imamura M. | Immunol. Lett., 83, 13-20 (2002). | 12060 | 12057850 |
Cloned cytosine deaminase gene expression of Bifidobacterium longum and application to enzyme/pro-drug therapy of hypoxic solid tumors. | Nakamura T., Sasaki T., Fujimori M., Yazawa K., Kano Y., Amano J., Taniguchi S. | Biosci. Biotechnol. Biochem., 66, 2362-2366 (2002). | 12059 | 12506973 |
Method for identification of mutant glutathione S-transferases conferring enhanced resistance to the anti-cancer drug chlorambucil. | Hirota K., Hanyu Y. | J. Biosci. Bioeng., 93, 618-621 (2002). | 12058 | 16233260 |
2001
Title | Author | Journal | NBRP RRC ID | PubMed PMID |
---|---|---|---|---|
Targeting the replication of adenovirus to p53-defective thyroid carcinoma with a p53-regulated Cre/loxP system. | Nagayama Y., Nishihara E., Namba H., Yokoi H., Hasegawa M., Mizuguchi H., Hayakawa T., Hamada H., Yamashita S., Niwa M. | Cancer Gene Ther., 8, 36-44 (2001). | 4788 | 11219492 |
Enhanced efficiency by centrifugal manipulation of adenovirus-mediated interleukin 12 gene transduction into human monocyte-derived dendritic cells. | Nishimura N., Nishioka Y., Shinohara T., Sone S. | Hum. Gene Ther., 12, 333-346 (2001). | 4787 | 11242526 |
Insulin-like growth factor I (IGF-I) protects cells from apoptosis by Alzheimer’s V642I mutant amyloid precursor protein through IGF-I receptor in an IGF-binding protein-sensitive manner. | Niikura T., Hashimoto Y., Okamoto T., Abe Y., Yasukawa T., Kawasumi M., Hiraki T., Kita Y., Terashita K., Kouyama K., Nishimoto I. | J. Neurosci., 21, 1902-1910 (2001). | 4786 | 11245675 |
Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures. | Suzuki A., Yamanaka T., Hirose T., Manabe N., Mizuno K., Shimizu M., Akimoto K., Izumi Y., Ohnishi T., Ohno S. | J. Cell Biol., 152, 1183-1196 (2001). | 4785 | 11257119 |
Antigen-specific T cell-mediated gene therapy in collagen-induced arthritis. | Nakajima A., Seroogy C.M., Sandora M.R., Tarner I.H., Costa G.L., Taylor-Edwards C., Bachmann M.H., Contag C.H., Fathman C.G. | J. Clin. Invest., 107, 1293-301 (2001). | 4783 | 11375419 |
A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promoters. | Kitagawa M., Oyama T., Kawashima T., Yedvobnick B., Kumar A., Matsuno K., Harigaya K. | Mol. Cell Biol., 21, 4337-4346 (2001). | 4782 | 11390662 |
Genetically modified bone marrow continuously supplies anti-inflammatory cells and suppresses renal injury in mouse Goodpasture syndrome. | Yokoo T., Ohashi T., Utsunomiya Y., Shen J.S., Hisada Y., Eto Y., Kawamura T., Hosoya T. | Blood, 98, 57-64 (2001). | 4781 | 11418463 |
Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis. | Ohba Y., Ikuta K., Ogura A., Matsuda J., Mochizuki N., Nagashima K., Kurokawa K., Mayer B.J., Maki K., Miyazaki J., Matsuda M. | EMBO J., 20, 3333-3341 (2001). | 4779 | 11432821 |
Expression of the oxygen-regulated protein ORP150 accelerates wound healing by modulating intracellular VEGF transport. | Ozawa K., Kondo T., Hori O., Kitao Y., Stern D.M., Eisenmenger W., Ogawa S., Ohshima T. | J. Clin. Invest., 108, 41-50 (2001). | 4778 | 11435456 |
Overexpression of EC-SOD suppresses endothelial-cell-mediated LDL oxidation. | Takatsu H., Tasaki H., Kim H.N., Ueda S., Tsutsui M., Yamashita K., Toyokawa T., Morimoto Y., Nakashima Y., Adachi T. | Biochem. Biophys. Res. Commun., 285, 84-91 (2001). | 4777 | 11437376 |
An unfolded putative transmembrane polypeptide, which can leado endoplasmic reticulum stress, is a substrate of Parkin. | Imai Y., Soda M., Inoue H., Hattori N., Mizuno Y., Takahashi R. | Cell, 105, 891-902 (2001). | 4776 | 11439185 |
Adoptive immunotherapy of experimental autoimmune encephalomyelitis via T cell delivery of the IL-12 p40 subunit. | Costa G.L., Sandora M.R., Nakajima A., Nguyen E.V., Taylor-Edwards C., Slavin A.J., Contag C.H., Fathman C.G., Benson J.M. | J. Immunol., 167, 2379-2387 (2001). | 4775 | 11490028 |
Induction of antitumor immunity by transduction of CD40 ligand gene and interferon-gamma gene into lung cancer. | Noguchi M., Imaizumi K., Kawabe T., Wakayama H., Horio Y., Sekido Y., Hara T., Hashimoto N., Takahashi M., Shimokata K., Hasegawa Y. | Cancer Gene Ther., 8, 421-429 (2001). | 4774 | 11498762 |
Accelerated degradation of cellular FLIP protein through the ubiquitin-proteasome pathway in p53-mediated apoptosis of human cancer cells. | Fukazawa T., Fujiwara T., Uno F., Teraishi F., Kadowaki Y., Itoshima T., Takata Y., Kagawa S., Roth J.A., Tschopp J., Tanaka N. | Oncogene, 20, 5225-5231 (2001). | 4772 | 11526513 |
PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex. | Yamanaka T., Horikoshi Y., Suzuki A., Sugiyama Y., Kitamura K., Maniwa R., Nagai Y., Yamashita A., Hirose T., Ishikawa H., Ohno S. | Genes Cells, 6, 721-731 (2001). | 4771 | 11532031 |
Cre/loxP-based reversible immortalization of human hepatocytes. | Kobayashi N., Noguchi H., Westerman K.A., Watanabe T., Matsumura T., Totsugawa T., Fujiwara T., Leboulch P., Tanaka N. | Cell Transplant., 10, 383-386 (2001). | 4770 | 11549058 |
Inflamed glomeruli-specific gene activation that uses recombinant adenovirus with the Cre/loxP system. | Yokoo T., Ohashi T., Utsunomiya Y., Shiba H., Shen J.S., Hisada Y., Eto Y., Kawamura T., Hosoya T. | J. Am. Soc. Nephrol., 12, 2330-2337 (2001). | 4769 | 11675409 |
Removal of the floxed neo gene from a conditional knockout allele by the adenoviral Cre recombinase in vivo. | Kaartinen V., Nagy A. | Genesis., 31, 126-129 (2001). | 4768 | 11747203 |
Identification of differentially expressed genes in hepatocellular carcinoma with cDNA microarrays. | Shirota Y., Kaneko S., Honda M., Kawai H.F., Kobayashi K. | Hepatology, 33, 832-840 (2001). | 4760 | 11283847 |
Successful retroviral gene transfer of simian virus 40 T antigen and herpes simplex virus-thymidine kinase into human hepatocytes. | Kobayashi, N., Noguchi, H., Westerman, K.A., Watanabe, T., Matsumura, T., Totsugawa, T., Fujiwara, T., Leboulch, P., Tanaka, N.. | Cell Transplant, 10 (4-5): 377-381 (2001). | 27177 | 11549057 |
Tumor suppressor protein VHL is induced at high cell density and mediates contact inhibition of cell growth. | Baba, M., Hirai, S., Kawakami, S., Kishida, T., Sakai, N., Kaneko, S., Yao, M., Shuin, T., Kubota, Y., Hosaka, M., Ohno, S. | Oncogene, 20 (22): 2727-2736 (2001). | 12747 | 11420685 |
Suppression of arthritis by forced expression of cyclin-dependent kinase inhibitor p21(Cip1) gene into the joints. | Nonomura Y., Koike R., Nishio J., Tsubata R., Kohsaka H., Kubota T., Miyasaka N. | Int. Immunol., 13, 723-731 (2001). | 12698 | 11369699 |
Ca(2+) mobilization, tyrosine hydroxylase activity, and signaling mechanisms in cultured porcine adrenal medullary chromaffin cells: effects of leptin. | Takekoshi K., Ishii K., Kawakami Y., Isobe K., Nanmoku T., Nakai T. | Endocrinology, 142, 290-298 (2001). | 12156 | 11145592 |
alpha-fetoprotein-producing hepatoma cell lines share common expression profiles of genes in various categories demonstrated by cDNA microarray analysis. | Kawai H.F., Kaneko S., Honda M., Shirota Y., Kobayashi K. | Hepatology, 33, 676-691 (2001). | 12155 | 11230749 |
Differential gene expression between chronic hepatitis B and C hepatic lesion. | Honda, M., Kaneko, S., Kawai, H., Shirota, Y., Kobayashi, K. | Gastroenterology., 120, 955-966 (2001). | 12154 | 11231949 |
alpha-Synuclein forms a complex with transcription factor Elk-1. | Iwata A., Miura S., Kanazawa I., Sawada M., Nukina N. | J. Neurochem., 77, 239-252 (2001). | 12153 | 11279280 |
Ulcerative proctitis, rectal prolapse, and intestinal pseudo-obstruction in transgenic mice overexpressing hepatocyte growth factor/scatter factor. | Takayama H., Takagi H., Larochelle W.J., Kapur R.P., Merlino G. | Lab. Invest., 81, 297-305 (2001). | 12152 | 11310823 |
Antitumor Effect on Murine Renal Cell Carcinoma by Autologous Tumor Vaccines Genetically Modified with Granulocyte-Macrophage Colony-Stimulating Factor and Interleukin-6 Cells. | Kinoshita Y., Kono T., Yasumoto R., Kishimoto T., Wang C.Y., Haas G.P., Nishisaka N. | J. Immunother (1991)., 24, 205-211 (2001). | 12151 | 11395635 |
Brain responses to acute withdrawal in phenobarbital-dependent rats. | Tanaka S., Okuno Y., Numazawa S., Yamamoto T., Shioda S., Yoshida T. | Eur. J. Pharmacol., 421, 101-108 (2001). | 12150 | 11399265 |
Rapidly functional immobilization of immortalized human hepatocytes using cell adhesive GRGDS peptide-carrying cellulose microspheres. | Kobayashi N., Taguchi T., Noguchi H., Okitsu T., Totsugawa T., Watanabe T., Matsumura T., Fujiwara T., Urata H., Kishimoto N., Hayashi N., Nakaji S., Murakami T., Tanaka N. | Cell Transplant., 10, 387-392 (2001). | 12069 | 11549059 |
alpha-Synuclein affects the MAPK pathway and accelerates cell death. | Iwata A., Maruyama M., Kanazawa I., Nukina N. | J. Biol. Chem., 276, 45320-45329 (2001). | 12068 | 11560921 |
Leptin stimulates catecholamine synthesis in a PKC-dependent manner in cultured porcine adrenal medullary chromaffin cells. | Takekoshi K., Ishii K., Nanmoku T., Shibuya S., Kawakami Y., Isobe K., Nakai T. | Endocrinology, 142, 4861-4871 (2001). | 12066 | 11606454 |
2000
Title | Author | Journal | NBRP RRC ID | PubMed PMID |
---|---|---|---|---|
The effects of cell adhesion on the growth and protein productivity of animal cells. | Nishijima K., Fujiki T., Kojima H., Iijima S. | Cytotechnology, 33, 147 – 155 (2000). | 28092 | 19002822 |
Dietary docosahexaenoic acid ameliorates, but rapeseed oil and safflower oil accelerate renal injury in stroke-prone spontaneously hypertensive rats as compared with soybean oil, which is associated with expression for renal transforming growth factor-beta, fibronectin and renin. | Miyazaki M., Takemura N., Watanabe S., Hata N., Misawa Y., Okuyama H. | Biochim. Biophys. Acta -Mol. Cell Biol. Lip., 1483, 101-110 (2000). | 12179 | 10601699 |
Endogenously Generated Nitric Oxide by Nitric-Oxide Synthase Gene Transfer Inhibits Cellular Proliferation. | Maeda Y., Ikeda U., Oya K., Shimpo M., Ueno S., Okada K., Saito T., Mano H., Ozawa K., Shimada K. | J. Pharmacol. Exp. Ther., 292, 387-393 (2000). | 12178 | 10604975 |
Shp-2 specifically regulates several tyrosine-phosphorylated proteins in brain-derived neurotrophic factor signaling in cultured cerebral cortical neurons. | Araki T., Yamada M., Ohnishi H., Sano S., Uetsuki T., Hatanaka H. | Neurochem., 74, 659-668 (2000). | 12177 | 10646517 |
Prevention of acute liver failure in rats with reversibly immortalized human hepatocytes. | Kobayashi N., Fujiwara T., Westerman K.A., Inoue Y., Sakaguchi M., Noguchi H., Miyazaki M., Cai J., Tanaka N., Fox I.J., Leboulch P. | Science, 287, 1258-1262 (2000). | 12176 | 10678831 |
The timing of GM-CSF expression plasmid administration influences the Th1/Th2 response induced by an HIV-1-specific DNA vaccine. | Kusakabe K., Xin K.Q., Katoh H., Sumino K., Hagiwara E., Kawamoto S., Okuda K., Miyagi Y., Aoki I., Nishioka K., Klinman D., Okuda K. | J. Immunol., 164, 3102-3111 (2000). | 12175 | 10706700 |
Role of c-jun expression increased by heat shock- and ceramide-activated caspase-3 in HL-60 cell apoptosis. Possible involvement of ceramide in heat shock-induced apoptosis. | Kondo T., Matsuda T., Kitano T., Takahashi A., Tashima M., Ishikura H., Umehara H., Domae N., Uchiyama T., Okazaki T. | J. Biol. Chem., 275, 7668-7676 (2000). | 12174 | 10713077 |
Suppression of heat shock protein-70 by ceramide in heat shock-induced HL-60 cell apoptosis. | Kondo T., Matsuda T., Tashima M., Umehara H., Domae N., Yokoyama K., Uchiyama T., Okazaki T. | J. Biol. Chem., 275, 8872-8879 (2000). | 12173 | 10722733 |
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. | Ko M.S., Kitchen J.R., Wang X., Threat T.A., Wang X., Hasegawa A., Sun T., Grahovac M.J., Kargul GJ, Lim MK, Cui Y, Sano Y, Tanaka T, Liang Y, Mason S., Paonessa P.D., Sauls A.D., DePalma G.E., Sharara R., Rowe L.B., Eppig J., Morrell C., Doi H. | Development, 127, 1737-1749 (2000). | 12172 | 10725249 |
Differential suppression of liver-specific genes in regenerating rat liver induced by extended hepatectomy. | Kurumiya Y., Nozawa K., Sakaguchi K., Nagino M., Nimura Y., Yoshida S. | J. Hepatol., 32, 636-644 (2000). | 12170 | 10782913 |
Glioma/glioblastoma-specific adenoviral gene expression using the nestin gene regulator. | Kurihara H., Zama A., Tamura M., Takeda J., Sasaki T., Takeuchi T. | Gene Ther., 7, 686-693 (2000). | 12169 | 10800092 |
Enhancement of adenovirus-mediated gene transfer into dermal fibroblasts in vitro and in vivo by polyethylene glycol 6000. | Ohsawa T., Nakamura T., Mihara M., Sato K. | J. Dermatol., 27, 244-251 (2000). | 12168 | 10824488 |
Effects of natriuretic peptides (ANP, BNP, CNP) on catecholamine synthesis and TH mRNA levels in PC12 cells. | Takekoshi K., Ishii K., Isobe K., Nomura F., Nammoku T., Nakai T. | Life Sci., 66, PL303-311 (2000). | 12167 | 10834306 |
kappa-Opioid inhibits catecholamine biosynthesis in PC12 rat pheochromocytoma cell. | Takekoshi K., Ishii K., Kawakami Y., Isobe K., Nakai T. | FEBS Lett., 477, 273-277 (2000). | 12165 | 10908734 |
Spleen-derived dendritic cells engineered to enhance interleukin-12 production elicit therapeutic antitumor immune responses. | Furumoto K., Arii S., Yamasaki S., Mizumoto M., Mori A., Inoue N., Isobe N., Imamura M. | Int. J. Cancer., 87, 665-672 (2000). | 12164 | 10925360 |
Interleukin-10 gene transfer improves the survival rate of mice inoculated with Escherichia coli. | Takakuwa T., Endo S., Shirakura Y., Yokoyama M., Tamatani M., Tohyama M., Aozasa K., Inada K. | Crit. Care. Med., 28, 2685-2689 (2000). | 12162 | 10966236 |
Geranylgeranylacetone stimulates mucin synthesis in cultured guinea pig gastric pit cells by inducing a neuronal nitric oxide synthase. | Rokutan K., Teshima S., Kawai T., Kawahara T., Kusumoro K., Mizushima T., Kishi K. | J. Gastroenterol., 35, 673-681 (2000). | 12161 | 11023038 |
Antigen-specific T cells transduced with IL-10 ameliorate experimentally induced arthritis without impairing the systemic immune response to the antigen. | Setoguchi K., Misaki Y., Araki Y., Fujio K., Kawahata K., Kitamura T., Yamamoto K. | J. Immunol., 165, 5980-5986 (2000). | 12160 | 11067961 |
G alpha(i) and G alpha(o) are target proteins of reactive oxygen species. | Nishida M., Maruyama Y., Tanaka R., Kontani K., Nagao T., Kurose H. | Nature, 408, 492-495 (2000). | 12159 | 11100733 |
Transfection of the plasma-type platelet-activating factor acetylhydrolase gene attenuates glutamate-induced apoptosis in cultured rat cortical neurons. | Hirashima Y., Ueno H., Karasawa K., Yokoyama K., Setaka M., Takaku A. | Brain Res., 885, 128-132 (2000). | 12158 | 11121539 |
A speedy method to detect inserted DNA fragment in cell lines transpected with retroviral vectors. | Ding, L-H, Iimura E., Saijo K., Hamada H., Ohno T. | Cytotechnology, 34, 243-252 (2000). | 12157 | 19003400 |
1999 and before
Title | Author | Journal | NBRP RRC ID | PubMed PMID |
---|---|---|---|---|
[Japanese text only] | Miura, M., Tanaka, S., Koike T. | Brain 21, 2, 221-227 (1999). | 33954 | |
Biochemical functions and mRNA expression of rat hepatocytes in a bioartifical liver module. | Okada S., Kono Y., Shiraki K. | Yonago Acta medica, 42, 103-112 (1999). | 12196 | |
Adenovirus-mediated gene expression in the septal cells of cirrhotic rat livers. | Nakamura T., Akiyoshi H., Saito I., Sato K. | J. Hepatol., 30, 101-106 (1999). | 12195 | 9927156 |
Wy-14,643, a peroxisome proliferator, inhibits compensative cell proliferation and hepatocyte growth factor mRNA expression in the rat liver. | Motoki Y., Tamura H., Watanabe T., Suga T. | Cancer Lett., 135, 145-150 (1999). | 12194 | 10096422 |
IL-6 synthesis by rheumatoid synoviocytes is autonomously upregulated at the transcriptional level. | Miyazawa K., Mori A., Okudaira H. | J. Allergy Clin. Immunol., 103, S437-444 (1999). | 12193 | 10329846 |
CrkL activates integrin-mediated hematopoietic cell adhesion through the guanine nucleotide exchange factor C3G. | Arai A., Nosaka Y., Kohsaka H., Miyasaka N., Miura O. | Blood., 93, 3713-3722 (1999). | 12192 | 10339478 |
Adenovirus-mediated transfer of wild-type p53 gene results in apoptosis or growth arrest in human cultured gastric carcinoma cells. | Tatebe S., Matsuura T., Endo K., Teramachi K., Nakamura T., Sato K., Ito H. | Int. J. Oncol., 15, 229-235 (1999). | 12191 | 10402231 |
Immunotherapy for lung metastases of murine renal cell carcinoma: synergy between radiation and cytokine-producing tumor vaccines. | Nishisaka N., Maini A., Kinoshita Y., Yasumoto R., Kishimoto T., Jones R.F., Morse P., Hillman G.G., Wang C.Y., Haas G.P. | J. Immunother., 22, 308-314 (1999). | 12190 | 10404432 |
Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13). | Yagasaki F., Jinnai I., Yoshida S., Yokoyama Y., Matsuda A., Kusumoto S., Kobayashi H., Terasaki H., Ohyashiki K., Asou N., Murohashi I., Bessho M., Hirashima K. | Gene. Chromosome. Canc., 26, 192-202 (1999). | 12189 | 10502316 |
Angiotensin II stimulates platelet-derived growth factor-B chain expression in newborn rat vascular smooth muscle cells and neointimal cells through Ras, extracellular signal-regulated protein kinase, and c-Jun N-terminal protein kinase mechanisms. | Deguchi J., Makuuchi M., Nakaoka T., Collins T., Takuwa Y. | Circ. Res., 85, 565-574 (1999). | 12188 | 10506481 |
Hepatoprotective action of adenovirus-transferred HNF-3gamma gene in acute liver injury caused by CCl4. | Nakamura T., Akiyoshi H., Shiota G., Isono M., Nakamura K., Moriyama M., Sato K. | FEBS Let., 459, 1-4 (1999). | 12187 | 10508906 |
CrkL mediates Ras-dependent activation of the Raf/ERK pathway through the guanine nucleotide exchange factor C3G in hematopoietic cells stimulated with erythropoietin or interleukin-3. | Nosaka Y., Arai A., Miyasaka N., Miura O. | J. Biol. Chem., 274, 30154-30162 (1999). | 12186 | 10514505 |
Asbestos-induced phosphorylation of epidermal growth factor receptor is linked to c-fos and apoptosis. | Zanella C.L., Timblin C.R., Cummins A., Jung M., Goldberg J., Raabe R., Tritton T.R., Mossman B.T. | Am. J. Physiol., 277, 684-693 (1999). | 12185 | 10516208 |
DNA immunization with Plasmodium falciparum serine repeat antigen: regulation of humoral immune response by coinoculation of cytokine expression plasmid. | Sakai T., Horii T., Hisaeda H., Zhang M., Ishii K., Nakano Y., Maekawa Y., Izumi K., Nitta Y., Miyazaki J., Himeno K. | Parasitol. Int., 48, 27-33 (1999). | 12182 | 11269323 |
Stretch activates jun N-terminal Kinase/Stress-activated protein kinase in vascular smooth muscle cells through mechanisms involving autocrine ATP stimulation of purinoceptors. | Hamada K., Takuwa N., Yokoyama K., Takuwa Y. | J. Biol. Chem., 273, 6334-6340 (1998). | 12210 | 9497362 |
Constitutive transcription of the human interleukin-6 gene by rheumatoid synoviocytes: spontaneous activation of NF-kappaB and CBF1. | Miyazawa K., Mori A., Yamamoto K., Okudaira H. | Am. J. Pathol., 152, 793-803 (1998). | 12209 | 9502421 |
Transcriptional roles of CCAAT/enhancer binding protein-beta, nuclear factor-kappaB, and C-promoter binding factor 1 in interleukin (IL)-1beta-induced IL-6 synthesis by human rheumatoid fibroblast-like synoviocytes. | Miyazawa K., Mori A., Yamamoto K., Okudaira H. | J. Biol. Chem., 273, 7620-7627 (1998). | 12208 | 9516466 |
Expression of mRNA coding for four catecholamine-synthesizing enzymes in human adrenal pheochromocytomas. | Isobe K., Nakai T., Yukimasa N., Nanmoku T., Takekoshi K., Nomura F. | Eur. J. Endocrinol., 138, 383-387 (1998). | 12207 | 9578504 |
Leptin receptor signal transduction: OBRa and OBRb of fa type. | Yamashita T., Murakami T., Otani S., Kuwajima M., Shima K. | Biochem. Biophys. Res. Commun., 246, 752-759 (1998). | 12206 | 9618284 |
Altered activities of transcription factors and their related gene expression in cardiac tissues of diabetic rats. | Nishio Y., Kashiwagi A., Taki H., Shinozaki K., Maeno Y., Kojima H., Maegawa H., Haneda M., Hidaka H., Yasuda H., Horiike K., Kikkawa R. | Diabetes., 47, 1318-1325 (1998). | 12205 | 9703334 |
Enhanced expression of heparin-binding EGF-like growth factor and its receptor in hypertrophied left ventricle of spontaneously hypertensive rats. | Fujino T., Hasebe N., Fujita M., Takeuchi K., Kawabe J., Tobise K., Higashiyama S., Taniguchi N., Kikuchi K. | Cardiovasc. Res., 38, 365-374 (1998). | 12204 | 9709397 |
Regulation of interleukin-1beta-induced interleukin-6 gene expression in human fibroblast-like synoviocytes by p38 mitogen-activated protein kinase. | Miyazawa K., Mori A., Miyata H., Akahane M., Ajisawa Y., Okudaira H. | J. Biol. Chem., 273, 24832-24838 (1998). | 12203 | 9733787 |
Oxygen tension regulates heme oxygenase-1 gene expression in mammalian cell lines. | Takahashi S., Takahashi Y., Yoshimi T., Miura T. | Cell Biochem. Funct., 16, 183-193 (1998). | 12202 | 9747510 |
A novel protein containing Cdc10/SWI6 motifs regulates expression of mRNA encoding catecholamine biosynthesizing enzymes. | Yamakuni T., Yamamoto T., Hoshino M., Song S.Y., Yamamoto H., Kunikata-Sumitomo M., Minegishi A., Kubota M., Ito M., Konishi S. | J. Biol. Chem., 273, 27051-27054 (1998). | 12201 | 9765218 |
Glutathione depletion inhibits oxidant-induced activation of nuclear factor-kappa B, AP-1, and c-Jun/ATF-2 in cultured guinea-pig gastric epithelial cells. | Rokutan K., Teshima S., Miyoshi M., Kawai T., Nikawa T., Kishi K. | J. Gastroenterol., 33, 646-655 (1998). | 12200 | 9773928 |
Adenovirus-transferred HNF-3 gamma conserves some liver functions in primary cultured hepatocytes of adult rats. | Nakamura T., Mura T., Saito K., Ohsawa T., Akiyoshi H., Sato K. | Biochem. Biophys. Res. Commun., 253, 352-357 (1998). | 12199 | 9878541 |
A newly developed adenovirus-mediated transfer of a wild-type p53 gene increases sensitivity to cis-diamminedichloroplatinum (II) in p53-deleted ovarian cancer cells. | Kanamori Y., Kigawa J., Minagawa Y., Irie T., Oishi T., Shimada M., Takahashi M., Nakamura T., Sato K., Terakawa N. | Eur. J. Cancer., 34, 1802-1806 (1998). | 12198 | 9893672 |
Heat shock protein expression in hearts hypertrophied by genetic and nongenetic hypertension. | Iwabuchi K., Tajima M., Isoyama S. | Heart Vessels., 13, 30-39 (1998). | 12197 | 9923563 |
Simultaneous triple fluorescence detection of mRNA localization, nuclear DNA, and apoptosis in cultured cells using confocal scanning laser microscopy. | Davis W.P., Janssen Y.M., Mossman B.T., Taatjes D.J. | Histochem. Cell Biol., 108, 307-311 (1997). | 33960 | 9387922 |
A short form of leptin receptor performs signal transduction. | Murakami T., Yamashita T., Iida M., Kuwajima M., Shima K. | Biochem. Biophys. Res. Commun., 231, 26-29 (1997). | 12218 | 9070213 |
Leptin receptor of Zucker fatty rat performs reduced signal transduction. | Yamashita T., Murakami T., Iida M., Kuwajima M., Shima K. | Diabetes, 46, 1077-1080 (1997). | 12216 | 9166683 |
Increases in the mRNA levels of gamma-glutamyltransferase and heme oxygenase-1 in the rat lung after ozone exposure. | Takahashi Y., Takahashi S., Yoshimi T., Miura T., Mochitate K., Kobayashi T. | Biochem. Pharmacol., 53, 1061-1064 (1997). | 12215 | 9174121 |
Decreased hepatocyte growth factor level by Wy-14,643, non-genotoxic hepatocarcinogen in F-344 rats. | Motoki Y., Tamura H., Morita R., Watanabe T., Suga T. | Carcinogenesis, 18, 1303-1309 (1997). | 12214 | 9230272 |
Oxidant-induced activation of nuclear factor-kappa B in cultured guinea pig gastric epithelial cells. | Rokutan K., Teshima S., Miyoshi M., Nikawa T., Kishi K. | Dig. Dis. Sci., 42, 1880-1889 (1997). | 12213 | 9331151 |
TSC-36 (follistatin-related polypeptide) gene expression in estrogen receptor positive osteoblastic cell line, CDO7F. | Ohashi T., Sato S., Yoshiki A., Kusakabe M. | Calcified. Tissue Int., 61, 400-403 (1997). | 12212 | 9351882 |
Development of a novel selective amplifier gene for controllable expansion of transduced hematopoietic cells. | Ito K., Ueda Y., Kokubun M., Urabe M., Inaba T., Mano H., Hamada H., Kitamura T., Mizoguchi H., Sakata T., Hasegawa M., Ozawa K. | Blood, 90, 3884-3892 (1997). | 9354655 | |
Detection of living cells that express AP1 using a fluorolabeled DNA probe. | Shimokawa, N., Miura, M. | FEBS Lett., 388, 16-20 (1996). | 12226 | 8654580 |
HLA-G gene polymorphism in a Japanese population. | Yamashita T., Fujii T., Watanabe Y., Tokunaga K., Tadokoro K., Juji T., Taketani Y. | Immunogenetics., 44, 186-191 (1996). | 12225 | 8662085 |
Suppressed expression of phenobarbital-inducible hepatic cytochrome P-450s in Eisai-hyperbilirubinuria rats (EHBR/Eis). | Oguro T., Kaneko E., Kaneko Y., Numazawa S., Imaoka S., Funae Y., Mikami T., Yoshida T. | J. Pharmacol. Exp. Ther., 277, 1676-1684 (1996). | 12224 | 8667238 |
A cardiotonic steroid bufalin-induced differentiation of THP-1 cells. Involvement of Na+, K(+)-ATPase inhibition in the early changes in proto-oncogene expression. | Numazawa S., Inoue N., Nakura H., Sugiyama T., Fujino E., Shinoki M., Yoshida T., Kuroiwa Y. | Biochem. Pharmacol., 52, 321-329 (1996). | 12223 | 8694857 |
An epidermal growth factor receptor/Jak2 tyrosine kinase domain chimera induces tyrosine phosphorylation of Stat5 and transduces a growth signal in hematopoietic cells. | Nakamura N., Chin H., Miyasaka N., Miura O. | J. Biol. Chem., 271, 19483-19488 (1996). | 12222 | 8702638 |
Pituitary adenylate cyclase-activating polypeptide induces gene expression of the catecholamine synthesizing enzymes, tyrosine hydroxylase and dopamine beta hydroxylase, through 3′,5′-cyclic adenosine monophosphate- and protein kinase C-dependent mechanisms in cultured porcine adrenal medullary chromaffin cells. | Isobe K., Yukimasa N., Nakai T., Takuwa Y. | Neuropeptides., 30, 167-175 (1996). | 12221 | 8771559 |
Construction and characterization of adenoviral vector expressing biologically active brain-derived neurotrophic factor. | Kojima H., Inuzuka S., Miwa T., Furukawa S., Hayashi K., Kanegae Y., Saito I., Ohishi N., Takamori M., Yagi K. | Biochem. Biophys. Res. Commun., 212, 712-717 (1995). | 12229 | 7542888 |
Requirement of AP-1 for ceramide-induced apoptosis in human leukemia HL-60 cells. | Sawai H., Okazaki T., Yamamoto H., Okano H., Takeda Y., Tashima M., Sawada H., Okuma M., Ishikura H., Umehara H., et al. | J. Biol. Chem., 270, 27326-27331 (1995). | 12228 | 7592995 |
Expression of mRNAs coding for catecholamine synthesizing enzymes in human adrenal pheochromocytoma. | Isobe K., Yukimasa N., Takekoshi K., Nomura F., Nakai T. | Jpn. J. Clin. Pathol., 43, 540-544 (1995). | 12227 | 7602797 |
Chimeric YACs were generated at unreduced rates in conditions that suppress coligation. | Wada M., Abe K., Okumura K., Taguchi H., Kohno K., Imamoto F., Schlessinger D., Kuwano M. | Nucleic. Acids. Res., 22, 1651-1654 (1994). | 12230 | 8202367 |
(GRP0065j 2019.11.12 T.M.)
2019.11.12