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Clontech Laboratories, Inc. and RIKEN BioResource Research Center concluded license agreement on preservation and distribution of Fluorescent Proteins, DsRed2 and mCherry for academic use

BRC News

Genes involved in the Notch signaling pathway


Fluorescent reporter clone of Notch signal activation

pRBS-EGFP expression clone

The pRBS-EGFP expression clone deposited by Dr. Makoto Mark Taketo, Graduate School of Medicine, Kyoto University allows you monitoring the state of activation of the Notch signaling by EGFP in living cells. The Notch signaling reporter construct containing the EGFP under the control of the Rbpj-binding sequences (RBS, hexamerized 50 bp EBNA2 response element of the TP-1 promoter) derived form the original plasmid pGA981-6 (TP1-luc(981-6)) deposited by Dr. Tasuku Honjo.


Depositor: Dr. Makoto Mark Taketo
Reference: Cancer Cell 19 (1): 125-137 (2011). PMID 21251616.
Press Release (2010, in Japanese)
Catalog no. Name of clone Running title Type
RDB08039 pRBS-EGFP Rbpj-binding sequence containing reporter GFP plasmid DNA clone

RBP-J-Venus expression clone

Fluorescent reporter clone of Notch signal activation

Depositor: Dr. Kenji Tanigaki

Reference: Neurosci. Res., 75 (3): 204-209 (2013). PMID 23396245.

Catalog no. Name of clone Running title
RDB08964 RBP-J-Venus Fluorescent reporter clone of Notch signal activation (transcriptional regulation by RBP-J)

Catalog no. Name of clone Running title
RDB06776 pGa981-6 Reporter construct containing the hexamerized 50 bp EBNA2 response element of the TP-1 promoter. TP1-luciferase reporter.
RDB06775 HES-1-Luc-Reporter Reporter construct of the mouse Hairy and enhancer of split 1.
RDB08039 pRBS-EGFP Rbpj-binding sequence containing reporter GFP plasmid
RDB08964 RBP-J-Venus Fluorescent reporter clone of Notch signal activation (transcriptional regulation by RBP-J)
RDB14127 pDll1-Ub-Fluc Reporter vector for time-lapse imaging of Dll1 transcription.
RDB14128 pDll1-Fluc Reporter vector for time-lapse imaging of Dll1 protein.

List of gene resources

Link to KEGG Pathway – Notch signaling pathway


(GSB0025e, 2012.04.06 T.M.)

2019.04.02