RDB13913 - pGL4.17 Tyk2 WT

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pGL4.17 Tyk2 WT

Reporter plasmid of mouse Tyk2 gene. WT promoter.

Catalog number	RDB13913
Resource name	pGL4.17 Tyk2 WT
Clone info.	Reporter plasmid of mouse Tyk2 gene. WT promoter region corresponding to 21,131,165 to 21,132,563 of NC_000075.6 was cloned from C57BL/6J.
Comment	Insert DNA is a PCR product. Froward: 5'- CCCGGTACCCCAGGGCTTTCTGGTTTGTA -3' and Reverse: 5'- CCCGCTAGCCACTCACCGTTTCCGGAGTA -3'. Function was confirmed by the depositor by luciferase assay. Please refer Fig.5 of Izumi, K., Nat. Commun. 6: 6748 (2015).
Vector backbone	pGL4.17[Luc2/Neo] (Plasmid)
Size of vector backbone	5.6 kb
Gene/insert name	Mouse Tyk2 genomic DNA
Depositor\|Developer	Nagafuchi, Seiho \|

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mouse Tyk2

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Mouse Tyk2

Reference sequence

Distribution information

Please check terms and conditions set forth by the depositor, which are specified in the RIKEN BRC Catalog and/or Web Catalog.

Terms and conditions set forth by the DEPOSITOR In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. (Izumi, K., Nat. Commun. 6: 6748, 2015)

Additional terms and conditions for distribution The use of the BIOLOGICAL RESOURCE is restricted to the academic researches conducted by non-profit organization. By using this material, the RECIPIENT agrees to be bound by the conditions of the limited use statement of the Promega Corporation.

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Terms and conditions set forth by the DEPOSITOR	In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. (Izumi, K., Nat. Commun. 6: 6748, 2015)
Additional terms and conditions for distribution	The use of the BIOLOGICAL RESOURCE is restricted to the academic researches conducted by non-profit organization. By using this material, the RECIPIENT agrees to be bound by the conditions of the limited use statement of the Promega Corporation.
Ordering	Please visit Information of Request for Distribution.[link] Order form [Credit Card Payment] [Bank Transfer Payment] Material Transfer Agreement (MTA for use for not-for-profit academic purpose) [Word]

提供条件	利用者は、研究成果の公表にあたって寄託者の指定する文献を引用する。(Izumi, K., Nat. Commun. 6: 6748, 2015)
付加的提供条件	本件リソースの使用は学術機関での学術研究に限る。本件リソースの使用にあたって、利用者はプロメガ社の限定使用条件に従う必要がある。
提供依頼	手続きの詳細は、「提供申込みについて[link]」をご覧ください。提供依頼書 [Word] 提供同意書 (MTA、非営利機関による非営利学術研究用)[Word]

Catalog #	Resource name	Availability	Shipping form	Fee (non-profit org.)
RDB13913	pGL4.17 Tyk2 WT	Under QC test. Please contact us.	DNA solution

Please wait for results of QC test to be uploaded. This clone will be sequenced a portion for examination.

References and tips

Electronic file

Original reference

original	Izumi, K., Reduced Tyk2 gene expression in beta-cells due to natural mutation determines susceptibility to virus-induced diabetes. Nat. Commun. 6: 6748 (2015). PMID 25849081.

Further references such as user reports and related articles (go to bottom)

Sequence information

check Please wait for results of QC test to be uploaded. This clone will be sequenced a portion for examination.

References

Original, user report and related articles

original	Izumi, K., Reduced Tyk2 gene expression in beta-cells due to natural mutation determines susceptibility to virus-induced diabetes. Nat. Commun. 6: 6748 (2015). PMID 25849081.

2022.05.17

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