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2014年

Resource Title Author Journal PMID
Ciona intestinalis EST Clones cibd016c12, ciad062k07, ciem809l11 Ciona intestinalis NADH dehydrogenase NDX confers stress-resistance and extended lifespan on Drosophila. Gospodaryov DV, Lushchak OV, Rovenko BM, Perkhulyn NV, Gerards M, Tuomela T, Jacobs HT. Biochim Biophys Acta. 1837(11): 1861-1869 (2014). 25124484
Genomic DNA of Bacillus halodurans JCM 9153 (JGD12232) Crystallization and preliminary X-ray diffraction analysis of YidC, a membrane-protein chaperone and insertase from Bacillus halodurans. Kumazaki K, Tsukazaki T, Nishizawa T, Tanaka Y, Kato HE, Nakada-Nakura Y, Hirata K, Mori Y, Suga H, Dohmae N, Ishitani R, Nureki O. Acta Crystallogr F Struct Biol Commun. 70(Pt 8): 1056-60 (2014). 25084381
8×3’Gli-BS-delta51-LucII (RDB08061); 8xm3’Gli-BS-delta51-LucII (RDB08062). Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett’s metaplasia. Wang DH, Tiwari A, Kim ME, Clemons NJ, Regmi NL, Hodges WA, Berman DM, Montgomery EA, Watkins DN, Zhang X, Zhang Q, Jie C, Spechler SJ, Souza RF. J Clin Invest. 124(9): 3767-80 (2014). 25083987
Genomic DNA of Thermus thermophilus JCM 10941T (JGD05989). Phylobiochemical characterization of class-ib aspartate/prephenate aminotransferases reveals evolution of the plant arogenate phenylalanine pathway. Dornfeld C, Weisberg AJ, K C R, Dudareva N, Jelesko JG, Maeda HA. Plant Cell. 26(7): 3101-14 (2014). 25070637
M01C028D08 (HGE091280) The role of Pak-interacting exchange factor-β phosphorylation at serines 340 and 583 by PKCγ in dopamine release. Shirafuji T, Ueyama T, Yoshino K, Takahashi H, Adachi N, Ago Y, Koda K, Nashida T, Hiramatsu N, Matsuda T, Toda T, Sakai N, Saito N. J Neurosci. 34(28): 9268-80 (2014). 25009260
c-erbB2 promoter(533)-pGL2-basic (RDB02839); pGL4-phESR1 (RDB07528) Screening to Identify Commonly Used Chinese Herbs That Affect ERBB2 and ESR1 Gene Expression Using the Human Breast Cancer MCF-7 Cell Line. Chiu JH, Chang CJ, Wu JC, Liu HJ, Wen CS, Hsu CH, Chen JL, Tseng LM, Chen WS, Shyr YM. Evid Based Complement Alternat Med. 2014(): 965486 (2014). 24987437
pRSFlag_mmSumo1 (RDB06126) Necdin promotes ubiquitin-dependent degradation of PIAS1 SUMO E3 ligase. Gur I, Fujiwara K, Hasegawa K, Yoshikawa K. PLoS One. 9(6): e99503 (2014). 24911587
pTK5 (RDB01027) Cancer cell specific cytotoxic gene expression mediated by ARF tumor suppressor promoter constructs. Kurayoshi K, Ozono E, Iwanaga R, Bradford AP, Komori H, Ohtani K. Biochem Biophys Res Commun. 450(1): 240-6 (2014). 24893334
hTRAIL/pMKITneo (RDB02934) YM155 sensitizes triple-negative breast cancer to membrane-bound TRAIL through p38 MAPK- and CHOP-mediated DR5 upregulation. Pennati M, Sbarra S, De Cesare M, Lopergolo A, Locatelli SL, Campi E, Daidone MG, Carlo-Stella C, Gianni AM, Zaffaroni N. Int J Cancer. (): (2014). 24866585
Common marmoset EST clones. Human speech- and reading-related genes display partially overlapping expression patterns in the marmoset brain. Kato M, Okanoya K, Koike T, Sasaki E, Okano H, Watanabe S, Iriki A. Brain Lang. 133(): 26-38 (2014). 24769279
Genomic DNA of Bacillus halodurans JCM 9153 (JGD12232). Structural basis of Sec-independent membrane protein insertion by YidC. Kumazaki K, Chiba S, Takemoto M, Furukawa A, Nishiyama K, Sugano Y, Mori T, Dohmae N, Hirata K, Nakada-Nakura Y, Maturana AD, Tanaka Y, Mori H, Sugita Y, Arisaka F, Ito K, Ishitani R, Tsukazaki T, Nureki O. Nature. 509(7501): 516-20 (2014). 24739968
B6N Mouse BAC clone, B6Ng01-170F09; B6Ng01-110O13. Neurogenin2-d4Venus and Gadd45g-d4Venus transgenic mice: visualizing mitotic and migratory behaviors of cells committed to the neuronal lineage in the developing mammalian brain. Kawaue T, Sagou K, Kiyonari H, Ota K, Okamoto M, Shinoda T, Kawaguchi A, Miyata T. Dev Growth Differ. 56(4): 293-304 (2014). 24712911
pEF-Flag-mSTAT3 (wild) (RDB02353). The adaptor TRAF5 limits the differentiation of inflammatory CD4(+) T cells by antagonizing signaling via the receptor for IL-6. Nagashima H, Okuyama Y, Asao A, Kawabe T, Yamaki S, Nakano H, Croft M, Ishii N, So T. Nat Immunol. 15(5): 449-56 (2014). 24681564
pCMFlag_hsOct3/4isoform1 (RDB06598). Bovine induced pluripotent stem cells are more resistant to apoptosis than testicular cells in response to mono-(2-ethylhexyl) phthalate. Lin YC, Kuo KK, Wuputra K, Lin SH, Ku CC, Yang YH, Wang SW, Wang SW, Wu DC, Wu CC, Chai CY, Lin CL, Lin CS, Kajitani M, Miyoshi H, Nakamura Y, Hashimoto S, Matsushima K, Jin C, Huang SK, Saito S, Yokoyama KK. Int J Mol Sci. 15(3): 5011-31 (2014). 24658443
Genomic DNA of Campylobacter jejuni subsp. jejuni JCM 2013 (JGD08023) Identification of a protein glycosylation operon from Campylobacter jejuni JCM 2013 and its heterologous expression in Escherichia coli. Srichaisupakit A, Ohashi T, Fujiyama K. J Biosci Bioeng. 118(3): 256-62 (2014). 24650731
Human MDR1 cDNA (RDB01372) The functional influences of common ABCB1 genetic variants on the inhibition of P-glycoprotein by Antrodia cinnamomea extracts. Sheu MJ, Teng YN, Chen YY, Hung CC. PLoS One. 9(2): e89622 (2014). 24586917
pGMH20 (RDB01956). High-throughput de novo screening of receptor agonists with an automated single-cell analysis and isolation system. Yoshimoto N, Tatematsu K, Iijima M, Niimi T, Maturana AD, Fujii I, Kondo A, Tanizawa K, Kuroda S. Sci Rep. 4(): 4242 (2014). 24577528
B6N Mouse BAC clone, B6Ng01-089N24. A combination of Wnt and growth factor signaling induces Arl4c expression to form epithelial tubular structures. Matsumoto S, Fujii S, Sato A, Ibuka S, Kagawa Y, Ishii M, Kikuchi A. EMBO J. 33(7): 702-18 (2014). 24562386
pCMFlag_hsIL1B (RDB06666). Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkcδ. Suzuki S, Franchi L, He Y, Munoz-Planillo R, Mimuro H, Suzuki T, Sasakawa C, Nunez G. PLoS Pathog. 10(2): e1003926 (2014). 24516390
S. pombe YFP-FLAG-His, SpYFH23B11 (SPW089235); SpYFH22C07 (SPW088855); SpYFH46F08 (SPW098528); SpYFH40H10 (SPW096178); SpYFH38C10 (SPW095258); SpYFH04F01 (SPW081721); SpYFH39B05 (SPW095629); SpYFH31D08 (SPW092480). RNAi mediates post-transcriptional repression of gene expression in fission yeast Schizosaccharomyces pombe. Smialowska A, Djupedal I, Wang J, Kylsten P, Swoboda P, Ekwall K. Biochem Biophys Res Commun. 444(2): 254-9 (2014). 24462781
pCAcc-Luc+ (RDB02443). Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors. Ge Z, Chen Q, Osada K, Liu X, Tockary TA, Uchida S, Dirisala A, Ishii T, Nomoto T, Toh K, Matsumoto Y, Oba M, Kano MR, Itaka K, Kataoka K. Biomaterials. 35(10): 3416-26 (2014). 24439417
pBMSA-PB2 (RDB01969). Crystallization and preliminary X-ray diffraction studies of a surface mutant of the middle domain of PB2 from human influenza A (H1N1) virus. Tsurumura T, Qiu H, Yoshida T, Tsumori Y, Tsuge H. Acta Crystallogr F Struct Biol Commun. 70(Pt 1): 26420 (2014). 24419622
pRx nZ ires Neo (RDB01699). Proliferation and survival signaling from both Jak2-V617F and Lyn involving GSK3 and mTOR/p70S6K/4EBP1 in PVTL-1 cell line newly established from acute myeloid leukemia transformed from polycythemia vera. Nagao T, Kurosu T, Umezawa Y, Nogami A, Oshikawa G, Tohda S, Yamamoto M, Miura O. PLoS One. 9(1): e84746 (2014). 24404189
GNP Clone, IRAK027I21 (HGX011013). Identification of residues required for stalled-ribosome rescue in the codon-independent release factor YaeJ. Kogure H, Handa Y, Nagata M, Kanai N, Guntert P, Kubota K, Nameki N. Nucleic Acids Res. 42(5): 3152-63 (2014). 24322300
AxdAdB3-F/RGD (RDB03012). Enhanced antitumor efficacy of integrin-targeted oncolytic adenovirus AxdAdB3-F/RGD on bladder cancer. Wang H, Cai Z, Yang F, Luo J, Satoh M, Arai Y, Li D. Urology. 83(2): 508.e13-9 (2014). 24315309
D-HA (RDB02139) Mental retardation-related protease, motopsin (prss12), binds to the BRICHOS domain of the integral membrane protein 2a. Mitsui S, Osako Y, Yuri K. Cell Biol Int. 38(1): 117-23 (2014). 23955961


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2013年

Resource Title Author Journal PMID
pBMSA-PB2 (RDB01969) Conformational Polymorphism of m(7)GTP in Crystal Structure of the PB2 Middle Domain from Human Influenza A Virus. Tsurumura T, Qiu H, Yoshida T, Tsumori Y, Hatakeyama D, Kuzuhara T, Tsuge H. PLoS One. 8(11): e82020 (2013). 24312396
pGL4-phSESN2 (RDB07413) Isorhamnetin protects against oxidative stress by activating Nrf2 and inducing the expression of its target genes. Yang JH, Shin BY, Han JY, Kim MG, Wi JE, Kim YW, Cho IJ, Kim SC, Shin SM, Ki SH. Toxicol Appl Pharmacol. 274(2): 293-301 (2013). 24211276
S. pombe YFP-FLAG-His, SpYFH08C03 (SPW083251). Subnuclear relocalization and silencing of a chromosomal region by an ectopic ribosomal DNA repeat. Jakociunas T, Domange Jordo M, Ait Mebarek M, Bunner CM, Verhein-Hansen J, Oddershede LB, Thon G. Proc Natl Acad Sci U S A. 110(47): E4465-73 (2013). 24191010
MSM Mouse BAC clone, MSMg01-329H21; MSMg01-362F04; MSMg01-544P17; MSMg01-494M12; MSMg01-419B05; MSMg01-148E20; MSMg01-355D01. Reciprocal virulence and resistance polymorphism in the relationship between Toxoplasma gondii and the house mouse. Lilue J, Muller UB, Steinfeldt T, Howard JC. Elife. 2(): e01298 (2013). 24175088
Y79(RBb) cDNA Clones, RBb11B10 (HKR324434). Involvement of a di-leucine motif in targeting of ABCC1 to the basolateral plasma membrane of polarized epithelial cells. Emi Y, Harada Y, Sakaguchi M. Biochem Biophys Res Commun. 441(1): 89-95 (2013). 24129190
pSTE33 (RDB00920) Identification, characterization and preliminary X-ray diffraction analysis of the rolling-circle replication initiator protein from plasmid pSTK1. Carr SB, Mecia LB, Phillips SE, Thomas CD. Acta Crystallogr Sect F Struct Biol Cryst Commun. 69(Pt 10): 1123-6 (2013). 24100563
pCMVluc+ (RDB03988) A novel aromatic carboxylic acid inactivates luciferase by acylation of an enzymatically active regulatory lysine residue. Nakagomi M, Fujimaki N, Ito A, Toda T, Fukasawa H, Shudo K, Tomita R. PLoS One. 8(9): e75445 (2013). 24066181
pCMFlag_hsHIF1A (RDB06378) Transcriptional upregulation of HIF-1α by NF-κB/p65 and its associations with β-catenin/p300 complexes in endometrial carcinoma cells. Yoshida T, Hashimura M, Mastumoto T, Tazo Y, Inoue H, Kuwata T, Saegusa M. Lab Invest. 93(11): 1184-93 (2013). 24042437
8xGT-IIC-LucII (RDB08067); pcDNA3.1-pA83-HA-Yap (RDB12190); pcDNA3.1-pA83-Lats2 (RDB12200) YAP and TAZ, Hippo signaling targets, act as a rheostat for nuclear SHP2 function. Tsutsumi R, Masoudi M, Takahashi A, Fujii Y, Hayashi T, Kikuchi I, Satou Y, Taira M, Hatakeyama M. Dev Cell. 26(6): 658-65 (2013). 24035415
pFBD-Hs alpha1CGH/beta3CGF (RDB12753); pFBD-Hs alpha1(K40R)CGH/beta3CGF (RDB12754). Overexpression, purification, and functional analysis of recombinant human tubulin dimer. Minoura I, Hachikubo Y, Yamakita Y, Takazaki H, Ayukawa R, Uchimura S, Muto E. FEBS Lett. 587(21): 566248 (2013). 24021646
pKM2L-phK5 (RDB05886) Functional conservation of Gsdma cluster genes specifically duplicated in the mouse genome. Tanaka S, Mizushina Y, Kato Y, Tamura M, Shiroishi T. G3 (Bethesda). 3(10): 1843-50 (2013). 23979942
pCALNL5 (RDB01862) Postnatal expression of BRAFV600E does not induce thyroid cancer in mouse models of thyroid papillary carcinoma. Shimamura M, Nakahara M, Orim F, Kurashige T, Mitsutake N, Nakashima M, Kondo S, Yamada M, Taguchi R, Kimura S, Nagayama Y. Endocrinology. 154(11): 4423-30 (2013). 23970782
Rat BAC RNB1 Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat. Atanur SS, Diaz AG, Maratou K, Sarkis A, Rotival M, Game L, Tschannen MR, Kaisaki PJ, Otto GW, Ma MC, Keane TM, Hummel O, Saar K, Chen W, Guryev V, Gopalakrishnan K, Garrett MR, Joe B, Citterio L, Bianchi G, McBride M, Dominiczak A, Adams DJ, Serikawa T, Flicek P, Cuppen E, Hubner N, Petretto E, Gauguier D, Kwitek A, Jacob H, Aitman TJ. Cell. 154(3): 691-703 (2013). 23890820
pCMFlag_hsCREB3L1 (RDB06267) Transcriptional regulation of mouse mesencephalic astrocyte-derived neurotrophic factor in Neuro2a cells. Oh-Hashi K, Hirata Y, Kiuchi K. Cell Mol Biol Lett. 18(3): 398-415 (2013). 23864333
pDUAL-YFH41c (RDB06152) Quantitative control of protein S-palmitoylation regulates meiotic entry in fission yeast. Zhang MM, Wu PY, Kelly FD, Nurse P, Hang HC. PLoS Biol. 11(7): e1001597 (2013). 23843742
Genomic DNA of Mouse KJR/Ms RBRC00655 New small molecule inhibitors of UPR activation demonstrate that PERK, but not IRE1α signaling is essential for promoting adaptation and survival to hypoxia. Cojocari D, Vellanki RN, Sit B, Uehling D, Koritzinsky M, Wouters BG. Radiother Oncol. 108(3): 541-7 (2013). 23830192
Genomic DNA of Thermotoga maritima JCM 10099T (JGD07695) Evolvability of thermophilic proteins from archaea and bacteria. Takano K, Aoi A, Koga Y, Kanaya S. Biochemistry. 52(28): 4774-80 (2013). 23822830
GNP Clone, IRAK141K24 (HGX056664). Diacylglycerol kinases terminate diacylglycerol signaling during the respiratory burst leading to heterogeneous phagosomal NADPH oxidase activation. Schlam D, Bohdanowicz M, Chatgilialoglu A, Steinberg BE, Ueyama T, Du G, Grinstein S, Fairn GD. J Biol Chem. 288(32): 23090-104 (2013). 23814057
GNP Clone, W01A023B19 (HGE009243). Generation of a large number of functional dendritic cells from human monocytes expanded by forced expression of cMYC plus BMI1. Haruta M, Tomita Y, Imamura Y, Matsumura K, Ikeda T, Takamatsu K, Nishimura Y, Senju S. Hum Immunol. 74(10): 1400-8 (2013). 23811433
Genomic DNA of Geobacillus kaustophilus JCM 20319T (JGD08098) Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT. Doki S, Kato HE, Solcan N, Iwaki M, Koyama M, Hattori M, Iwase N, Tsukazaki T, Sugita Y, Kandori H, Newstead S, Ishitani R, Nureki O. Proc Natl Acad Sci U S A. 110(28): 11343-8 (2013). 23798427
pcDNA3.1-pA83-aPKC lambda KD (RDB012202); HA-Amot130/pcDNA3.1-pA83 (RDB012203); HA-Amot80/pcDNA3.1-pA83 (RDB012204); HA-Amot130-delta CC/pcDNA3.1-pA83 (RDB012205); HA-Amot130-m5/pcDNA3.1-pA83 (RDB012206); HA-Amot130-delta PDZbd/pcDNA3.1-pA83 (RDB012207); HA-Amot130-S176A/pcDNA3.1-pA83 (RDB012208); HA-Amot130-S176E/pcDNA3.1-pA83 (RDB012209); HA-Merlin/pCAG-pA83 (RDB012210); HA-Amot-delta(45-100)/pcDNA3.1-pA83 (RDB012211); HA-Amot-delta(101-141)/pcDNA3.1-pA83 (RDB012212); pCMV/SV-Flag-Lats2 (RDB012213); pCMV/SV-Flag-Lats2-KD (RDB012214); Ecad-Flag/pCAG (RDB012215); E-Cadherin-delta C-Flag/pCAG (RDB012216) Polarity-dependent distribution of angiomotin localizes Hippo signaling in preimplantation embryos. Hirate Y, Hirahara S, Inoue K, Suzuki A, Alarcon VB, Akimoto K, Hirai T, Hara T, Adachi M, Chida K, Ohno S, Marikawa Y, Nakao K, Shimono A, Sasaki H. Curr Biol. 23(13): 1181-94 (2013). 23791731
pBMSA-PA (RDB01971) Anti-influenza activity of c60 fullerene derivatives. Shoji M, Takahashi E, Hatakeyama D, Iwai Y, Morita Y, Shirayama R, Echigo N, Kido H, Nakamura S, Mashino T, Okutani T, Kuzuhara T. PLoS One. 8(6): e66337 (2013). 23785493
D-HA (RDB02139); pCALwL (RDB01679) A mental retardation gene, motopsin/prss12, modulates cell morphology by interaction with seizure-related gene 6. Mitsui S, Hidaka C, Furihata M, Osako Y, Yuri K. Biochem Biophys Res Commun. 436(4): 638-44 (2013). 23770366
Rat BAC RNB2. Combined sequence-based and genetic mapping analysis of complex traits in outbred rats. Rat Genome Sequencing and Mapping Consortium, Baud A, Hermsen R, Guryev V, Stridh P, Graham D, McBride MW, Foroud T, Calderari S, Diez M, Ockinger J, Beyeen AD, Gillett A, Abdelmagid N, Guerreiro-Cacais AO, Jagodic M, Tuncel J, Norin U, Beattie E, Huynh N, Miller WH, Koller DL, Alam I, Falak S, Osborne-Pellegrin M, Martinez-Membrives E, Canete T, Blazquez G, Vicens-Costa E, Mont-Cardona C, Diaz-Moran S, Tobena A, Hummel O, Zelenika D, Saar K, Patone G, Bauerfeind A, Bihoreau MT, Heinig M, Lee YA, Rintisch C, Schulz H, Wheeler DA, Worley KC, Muzny DM, Gibbs RA, Lathrop M, Lansu N, Toonen P, Ruzius FP, de Bruijn E, Hauser H, Adams DJ, Keane T, Atanur SS, Aitman TJ, Flicek P, Malinauskas T, Jones EY, Ekman D, Lopez-Aumatell R, Dominiczak AF, Johannesson M, Holmdahl R, Olsson T, Gauguier D, Hubner N, Fernandez-Teruel A, Cuppen E, Mott R, Flint J. Nat Genet. 45(7): 767-75 (2013). 23708188
pEF-BOSneo-mNotch1 RAMIC (RDB06771) Wnt signaling regulates left-right axis formation in the node of mouse embryos. Kitajima K, Oki S, Ohkawa Y, Sumi T, Meno C. Dev Biol. 380(2): 222-32 (2013). 23707899
Genomic DNA of Archaeoglobus fulgidus JCM 9628T (JGD06275). Structural basis for the counter-transport mechanism of a H+/Ca2+ exchanger. Nishizawa T, Kita S, Maturana AD, Furuya N, Hirata K, Kasuya G, Ogasawara S, Dohmae N, Iwamoto T, Ishitani R, Nureki O. Science. 341(6142): 168-72 (2013). 23704374
Thermus thermophilus expression plasmid set, TEx18D08; TEx18C04. MutS stimulates the endonuclease activity of MutL in an ATP-hydrolysis-dependent manner. Shimada A, Kawasoe Y, Hata Y, Takahashi TS, Masui R, Kuramitsu S, Fukui K. FEBS J. 280(14): 3467-79 (2013). 23679952
Thermus thermophilus HB8 gene disruption plasmid, TTHA1294: TDs07A03. Conservation of two distinct types of 100S ribosome in bacteria. Ueta M, Wada C, Daifuku T, Sako Y, Bessho Y, Kitamura A, Ohniwa RL, Morikawa K, Yoshida H, Kato T, Miyata T, Namba K, Wada A. Genes Cells. 18(7): 554-74 (2013). 23663662
pGL4-phSESN2 (RDB07413) Resveratrol inhibits LXRα-dependent hepatic lipogenesis through novel antioxidant Sestrin2 gene induction. Jin SH, Yang JH, Shin BY, Seo K, Shin SM, Cho IJ, Ki SH. Toxicol Appl Pharmacol. 271(1): 95-105 (2013). 23651738
S. pombe YFP-FLAG-His, SpYFH06D01 (SPW082473); SpYFH25C07 (SPW090055). A proteome-wide visual screen identifies fission yeast proteins localizing to DNA double-strand breaks. Yu Y, Ren JY, Zhang JM, Suo F, Fang XF, Wu F, Du LL. DNA Repair (Amst). 12(6): 433-43 (2013). 23628481
pBR-lacZ alpha (RDB12261) Quantitative assay for TALEN activity at endogenous genomic loci. Hisano Y, Ota S, Arakawa K, Muraki M, Kono N, Oshita K, Sakuma T, Tomita M, Yamamoto T, Okada Y, Kawahara A. Biol Open. 2(4): 363-7 (2013). 23616919
S. pombe entry SpEnt26D11 (SPW010483). Structure of the lectin mannose 6-phosphate receptor homology (MRH) domain of glucosidase II, an enzyme that regulates glycoprotein folding quality control in the endoplasmic reticulum. Olson LJ, Orsi R, Alculumbre SG, Peterson FC, Stigliano ID, Parodi AJ, D’Alessio C, Dahms NM. J Biol Chem. 288(23): 16460-75 (2013). 23609449
Thermus thermophilus expression plasmid set, TTHA0345: TEx06D08; TTHA1598: TEx10C08; TTHA1507: TEx05A05. Production of uroporphyrinogen III, which is the common precursor of all tetrapyrrole cofactors, from 5-aminolevulinic acid by Escherichia coli expressing thermostable enzymes. Hibino A, Petri R, Buchs J, Ohtake H. Appl Microbiol Biotechnol. 97(16): 7337-44 (2013). 23604563
Genomic DNA of Mouse Mol-Mae/Stm RBRC00431; Genomic DNA of Mouse STM1 RBRC00265; Genomic DNA of Mouse STM2 RBRC00266; Genomic DNA of Mouse MOM RBRC01837. The ancestor of extant Japanese fancy mice contributed to the mosaic genomes of classical inbred strains. Takada T, Ebata T, Noguchi H, Keane TM, Adams DJ, Narita T, Shin-I T, Fujisawa H, Toyoda A, Abe K, Obata Y, Sakaki Y, Moriwaki K, Fujiyama A, Kohara Y, Shiroishi T. Genome Res. 23(8): 1329-38 (2013). 23604024
MSM Mouse BAC clone, MSMg01-261K04. WDR81 is necessary for purkinje and photoreceptor cell survival. Traka M, Millen KJ, Collins D, Elbaz B, Kidd GJ, Gomez CM, Popko B. J Neurosci. 33(16): 6834-44 (2013). 23595742
Genomic DNA of Pyrococcus furiosus JCM 8422T (JGD07704), An archaeal homolog of proteasome assembly factor functions as a proteasome activator. Kumoi K, Satoh T, Murata K, Hiromoto T, Mizushima T, Kamiya Y, Noda M, Uchiyama S, Yagi H, Kato K. PLoS One. 8(3): e60294 (2013). 23555947
Thermus thermophilus expression plasmid set, TTHA1435. Unique substrate specificity of purine nucleoside phosphorylases from Thermus thermophilus. Tomoike F, Kuramitsu S, Masui R. Extremophiles. 17(3): 505-14 (2013). 23546840
Common marmoset cDNA library Development and characterization of cDNA resources for the common marmoset: one of the experimental primate models. Tatsumoto S, Adati N, Tohtoki Y, Sakaki Y, Boroviak T, Habu S, Okano H, Suemizu H, Sasaki E, Satake M. DNA Res. 20(3): 255-62 (2013). 23543116
Genomic DNA of Pyrococcus furiosus JCM 8422T (JGD07704). Structural basis for the drug extrusion mechanism by a MATE multidrug transporter. Tanaka Y, Hipolito CJ, Maturana AD, Ito K, Kuroda T, Higuchi T, Katoh T, Kato HE, Hattori M, Kumazaki K, Tsukazaki T, Ishitani R, Suga H, Nureki O. Nature. 496(7444): 247-51 (2013). 23535598
Human MDR1 cDNA (RDB01372) Functional impact of ABCB1 variants on interactions between P-glycoprotein and methadone. Hung CC, Chiou MH, Teng YN, Hsieh YW, Huang CL, Lane HY. PLoS One. 8(3): e59419 (2013). 23527191
Thermus thermophilus expression plasmid set, TTHA1588. Crystallization and preliminary X-ray analysis of peptidyl-tRNA hydrolase from Thermus thermophilus HB8. Matsumoto A, Shimizu Y, Takemoto C, Ueda T, Uchiumi T, Ito K. Acta Crystallogr Sect F Struct Biol Cryst Commun. 69(Pt 3): 332-5 (2013). 23519816
pRS416-PADH1-ccdB-yEGFP-TTEF1 (RDB08380); pDONR221-GAP1 (RDB08381); pDONR221-PUT4 (RDB08382); pDONR221-AGP1 (RDB08383); pDONR221-GNP1 (RDB08384); pDONR221-gap1[K9R/K16R] (RDB08385); pRS416-PADH1-yEGFP-TTEF1 (RDB08386); pRS416-PADH1-GAP1-yEGFP-TTEF1 (RDB08387); pRS416-PADH1-PUT4-yEGFP-TTEF1 (RDB08388); pRS416-PADH1-AGP1-yEGFP-TTEF1 (RDB08389); pRS416-PADH1-GNP1-yEGFP-TTEF1 (RDB08390); pRS416-PADH1-gap1[K9R/K16R]yEGFP-TTEF1 (RDB08391) Phosphorylation of a conserved Thr357 in yeast Nedd4-like ubiquitin ligase Rsp5 is involved in down-regulation of the general amino acid permease Gap1. Sasaki T, Takagi H. Genes Cells. 18(6): 459-75 (2013). 23517290
pGEM3Zf_hsLIN28 (RDB06427); pCMV_S-FLAG (RDB05956) Lin28a is a putative factor in regulating cancer stem cell-like properties in side population cells of oral squamous cell carcinoma. Hayashi S, Tanaka J, Okada S, Isobe T, Yamamoto G, Yasuhara R, Irie T, Akiyama C, Kohno Y, Tachikawa T, Mishima K. Exp Cell Res. 319(8): 1220-8 (2013). 23500413
pCMV-MAZ (RDB03219); pGEX-hMAZ (RDB05701) MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice. Cogoi S, Zorzet S, Rapozzi V, Geci I, Pedersen EB, Xodo LE. Nucleic Acids Res. 41(7): 4049-64 (2013). 23471001
pDUAL-YFH1c (RDB06151); SpYFH30G11 (SPW092155); SpYFH39H12 (SPW095780); SpYFH13E01 (SPW085297); SpYFH36D10 (SPW094482); SpYFH36G05 (SPW094549). Haploinsufficiency of the Sec7 guanine nucleotide exchange factor gea1 impairs septation in fission yeast. Eckler AM, Wilder C, Castanon A, Ferris VM, Lamere RA, Perrin BA, Pearlman R, White B, Byrd C, Ludvik N, Nichols N, Poole-Sumrall K, Sztul E, Styers ML. PLoS One. 8(2): e56807 (2013). 23457617
His-Xpress-RALT (RDB012225); Flag-Chk1 (1-365) (RDB012229); His-Xpress-RALT S250A mutant (RDB012226); SNAP-RALT (RDB012227); SNAP-RALT S250A mutant (RDB012228); Flag-Chk1 (1-365) K38M mutant (RDB012230) Chk1-mediated phosphorylation of receptor-associated late transducer at serine 250 increases its stability by stimulating its interaction with 14-3-3. Takeda K, Takata T, Kawai Y, Ishigaki Y, Kajinami K. Genes Cells. 18(5): 369-86 (2013). 23432726
RBP-J-Venus (RDB08964) Notch signaling regulates nucleocytoplasmic Olig2 translocation in reactive astrocytes differentiation after ischemic stroke. Marumo T, Takagi Y, Muraki K, Hashimoto N, Miyamoto S, Tanigaki K. Neurosci Res. 75(3): 204-9 (2013). 23396245
pDUAL-FFH51 (RDB06537), pDUAL2-HFG1 (RDB06196) Display of active beta-glucosidase on the surface of Schizosaccharomyces pombe cells using novel anchor proteins. Tanaka T, Matsumoto S, Yamada M, Yamada R, Matsuda F, Kondo A. Appl Microbiol Biotechnol. 97(10): 4343-52 (2013). 23385477
X. laevis whole embryo(stage 25) EST clones XL099E15. Regulation of G-protein signaling via Gnas is required to regulate proximal tubular growth in the Xenopus pronephros. Zhang B, Romaker D, Ferrell N, Wessely O. Dev Biol. 376(1): 31-42 (2013). 23352791
pCALNLZ (RDB01680) A novel reporter rat strain that expresses LacZ upon Cre-mediated recombination. Fukamachi K, Tanaka H, Sakai Y, Alexander DB, Futakuchi M, Tsuda H, Suzui M. Genesis. 51(4): 268-74 (2013). 23349063
IRAK013J04 (HGX005420). Dimerization of Sir3 via its C-terminal winged helix domain is essential for yeast heterochromatin formation. Oppikofer M, Kueng S, Keusch JJ, Hassler M, Ladurner AG, Gut H, Gasser SM. EMBO J. 32(3): 437-49 (2013). 23299941
pGCDNsam-Fam57b_var1-IRES-EGFP(IG) (RDB12135); pGCDNsam-Fam57b_var1FLAG-IG (RDB12136); pGCDNsam-Fam57b_var2-IG (RDB12137); pGCDNsam-Fam57b_var2FLAG-IG (RDB12138); pGCDNsam-Fam57b_var3-IG (RDB12139); pGCDNsam-Fam57b_var3FLAG-IG (RDB12140) Fam57b (family with sequence similarity 57, member B), a novel peroxisome proliferator-activated receptor γ target gene that regulates adipogenesis through ceramide synthesis. Yamashita-Sugahara Y, Tokuzawa Y, Nakachi Y, Kanesaki-Yatsuka Y, Matsumoto M, Mizuno Y, Okazaki Y. J Biol Chem. 288(7): 4522-37 (2013). 23275342
Genome Network Project Gateway Entry Clone Set Enhanced expression of myogenic differentiation factors and skeletal muscle proteins in human amnion-derived cells via the forced expression of MYOD1. Akizawa Y, Kanno H, Kawamichi Y, Matsuda Y, Ohta H, Fujii H, Matsui H, Saito K. Brain Dev. 35(4): 349-55 (2013). 22727434
pMT-PURO2G (RDB09004); pMT-PURO2 (RDB12152) Fusion of fluorescent protein to puromycin N-acetyltransferase is useful in Drosophila Schneider S2 cells expressing heterologous proteins. Nagahashi K, Umemura K, Kanayama N, Iwaki T. Cytotechnology. 65(2): 173-8 (2013). 22706964
pCALNL5 (RDB01862) Excitatory cortical neurons with multipolar shape establish neuronal polarity by forming a tangentially oriented axon in the intermediate zone. Hatanaka Y, Yamauchi K. Cereb Cortex. 23(1): 105-13 (2013). 22267309
Mouse E-cadherin full length cDNA (RDB01184) Direct observation of cell cycle progression in living mouse embryonic stem cells on an extracellular matrix of E-cadherin. Jovic, D., Sakaue-Sawano, A., Abe, T., Cho, C.C., Nagaoka, N., Miyawaki, A., Akaike, T. SpringerPlus 2: 585 (2013).
Mouse E-cadherin full length cDNA (RDB01184) E-Cadherin ?EFc Chimeric Protein-Based Biomaterial: Breaking the Barriers in Stem Cell Technology and Regenerative Medicine. Nag, K., Akaike, T. Advanced Materials Research 810: 41-76 (2013).


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2012年

Resource Title Author Journal PMID
hTRAIL/pMKITneo (RDB02934) Surveillance of spontaneous breast cancer metastasis by TRAIL-expressing CD34? cells in a xenograft model. Rossini A, Giussani M, Giacomini A, Guarnotta C, Tagliabue E, Balsari A. Breast Cancer Res Treat. 136(2): 457-67 (2012). 23053664
MSM Mouse BAC clone Molecular cytogenetic identification and characterization of Robertsonian chromosomes in the large Japanese field mouse (Apodemus speciosus) using FISH. Yamagishi M, Matsubara K, Sakaizumi M. Zoolog Sci. 29(10): 709-13 (2012). 23030344
pEF-Flag-mSTATY705F (RDB02354) Transcriptional regulation of the interleukin-11 gene by oncogenic Ras. Shin SY, Choi C, Lee HG, Lim Y, Lee YH. Carcinogenesis. 33(12): 2467-76 (2012). 23027619
pMXs-GMT2A (RDB12141); pMXs-TMG2A (RDB12142) Induction of cardiomyocyte-like cells in infarct hearts by gene transfer of Gata4, Mef2c, and Tbx5. Inagawa K, Miyamoto K, Yamakawa H, Muraoka N, Sadahiro T, Umei T, Wada R, Katsumata Y, Kaneda R, Nakade K, Kurihara C, Obata Y, Miyake K, Fukuda K, Ieda M. Circ Res. 111(9): 1147-56 (2012). 22931955
Rat BAC RNB1-043O06; Rat BAC RNB2-482C01. Origins of albino and hooded rats: implications from molecular genetic analysis across modern laboratory rat strains. Kuramoto T, Nakanishi S, Ochiai M, Nakagama H, Voigt B, Serikawa T. PLoS One. 7(8): e43059 (2012). 22916206
Genome Network Project Gateway Entry Clone Set Establishment of single-cell screening system for the rapid identification of transcriptional modulators involved in direct cell reprogramming. Shin JW, Suzuki T, Ninomiya N, Kishima M, Hasegawa Y, Kubosaki A, Yabukami H, Hayashizaki Y, Suzuki H. Nucleic Acids Res. 40(21): e165 (2012). 22879381
pAxCALNLhMMP13(forward) (RDB03598) Osterix regulates calcification and degradation of chondrogenic matrices through matrix metalloproteinase 13 (MMP13) expression in association with transcription factor Runx2 during endochondral ossification. Nishimura R, Wakabayashi M, Hata K, Matsubara T, Honma S, Wakisaka S, Kiyonari H, Shioi G, Yamaguchi A, Tsumaki N, Akiyama H, Yoneda T. J Biol Chem. 287(40): 33179-90 (2012). 22869368
pAxEFwtit2 (RDB05215), pxCAG (RDB02546) Efficient recombinant production in mammalian cells using a novel IR/MAR gene amplification method. Araki Y, Hamafuji T, Noguchi C, Shimizu N. PLoS One. 7(7): e41787 (2012). 22844523
pBluescript SKII+mIL10 (RDB01476) Development of an optimized tetracycline-inducible expression system to increase the accumulation of interleukin-10 in tobacco BY-2 suspension cells. Bortesi L, Rademacher T, Schiermeyer A, Schuster F, Pezzotti M, Schillberg S. BMC Biotechnol. 12(): 40 (2012). 22784336
pCMFlag_hsNR5A1 (RDB06299) Differentiation of human embryonic stem cells and human induced pluripotent stem cells into steroid-producing cells. Sonoyama T, Sone M, Honda K, Taura D, Kojima K, Inuzuka M, Kanamoto N, Tamura N, Nakao K. Endocrinology. 153(9): 4336-45 (2012). 22778223
Genomic DNA of Aeropyrum pernix JCM 9820T (JGD07499) Structural basis for translation termination by archaeal RF1 and GTP-bound EF1α complex. Kobayashi K, Saito K, Ishitani R, Ito K, Nureki O. Nucleic Acids Res. 40(18): 9319-28 (2012). 22772989
Thermus thermophilus expression plasmid set In-cell NMR of intrinsically disordered proteins in prokaryotic cells. Ito Y, Mikawa T, Smith BO. Methods Mol Biol. 895(): 19-31 (2012). 22760309
pGL4-phSESN2 (RDB07413) Nrf2-ARE pathway regulates induction of Sestrin-2 expression. Shin BY, Jin SH, Cho IJ, Ki SH. Free Radic Biol Med. 53(4): 834-41 (2012). 22749810
pAxCALNLhIL-3R alpha(forward) (RDB04994) Opposing regulation of PROX1 by interleukin-3 receptor and NOTCH directs differential host cell fate reprogramming by Kaposi sarcoma herpes virus. Yoo J, Lee HN, Choi I, Choi D, Chung HK, Kim KE, Lee S, Aguilar B, Kang J, Park E, Lee YS, Maeng YS, Kim NY, Koh CJ, Hong YK. PLoS Pathog. 8(6): e1002770 (2012). 22719258
pDUAL-FFH1c (RDB06142); S. pombe FLAG2-His, SpFFH20F06 (SPW048126), SpFFH47B10 (SPW058834), Constitutively active Cullin-RING-Ligases fail to rescue loss of NEDD8 conjugation in Schizosaccharomyces pombe. Girdwood D, Robertson M, Gordon C. FEBS Lett. 586(10): 1522-8 (2012). 22673520
pEF-BOSneo-mNotch1 RAMIC (RDB06771); HES-1-Luc-Reporter (RDB07290) Casitas B-cell lymphoma mutation in childhood T-cell acute lymphoblastic leukemia. Saito Y, Aoki Y, Muramatsu H, Makishima H, Maciejewski JP, Imaizumi M, Rikiishi T, Sasahara Y, Kure S, Niihori T, Tsuchiya S, Kojima S, Matsubara Y. Leuk Res. 36(8): 1009-15 (2012). 22591685
pBSCiHox1 (RDB08929) Retinoic acid-driven Hox1 is required in the epidermis for forming the otic/atrial placodes during ascidian metamorphosis. Sasakura Y, Kanda M, Ikeda T, Horie T, Kawai N, Ogura Y, Yoshida R, Hozumi A, Satoh N, Fujiwara S. Development. 139(12): 2156-60 (2012). 22573621
pISRE-TK hRluc(F) (RDB05610) Suppression of feline coronavirus replication in vitro by cyclosporin A. Tanaka Y, Sato Y, Osawa S, Inoue M, Tanaka S, Sasaki T. Vet Res. 43(1): 41 (2012). 22546085
pKM2L-phP21 (RDB05893) TATA-binding protein (TBP)-like protein is required for p53-dependent transcriptional activation of upstream promoter of p21Waf1/Cip1 gene. Suzuki H, Ito R, Ikeda K, Tamura TA. J Biol Chem. 287(24): 19792-803 (2012). 22511763
pCAcc-Luc+ (RDB02443) Homo-catiomer integration into PEGylated polyplex micelle from block-catiomer for systemic anti-angiogenic gene therapy for fibrotic pancreatic tumors. Chen Q, Osada K, Ishii T, Oba M, Uchida S, Tockary TA, Endo T, Ge Z, Kinoh H, Kano MR, Itaka K, Kataoka K. Biomaterials. 33(18): 4722-30 (2012). 22444644
Thermus thermophilus expression plasmid set Discovery and analysis of cofactor-dependent phosphoglycerate mutase homologs as novel phosphoserine phosphatases in Hydrogenobacter thermophilus. Chiba Y, Oshima K, Arai H, Ishii M, Igarashi Y. J Biol Chem. 287(15): 11934-41 (2012). 22337887
pCMX-N/RBP-J (RDB03021) Reduction of NOTCH1 expression pertains to maturation abnormalities of keratinocytes in squamous neoplasms. Sakamoto K, Fujii T, Kawachi H, Miki Y, Omura K, Morita K, Kayamori K, Katsube K, Yamaguchi A. Lab Invest. 92(5): 688-702 (2012). 22330335
pGEX6P1- PIP5Kc661 Cterm-WT(434-661 a.a.) (RDB08477); pGEX6P1- PIP5Kc661 Cterm-SA(434-661 a.a.) (RDB08478); pGEX6P1- PIP5Kc661 Cterm-SE(434-661 a.a.) (RDB08479); pGEX6P1- PIP5Kc661 C26aa-SA(636-661 a.a.) (RDB08480); pGEX6P1- PIP5Kc661 C26aa-SE(636-661 a.a.) (RDB08481) NMDA receptor-mediated PIP5K activation to produce PI(4,5)P?Eis essential for AMPA receptor endocytosis during LTD. Unoki T, Matsuda S, Kakegawa W, Van NT, Kohda K, Suzuki A, Funakoshi Y, Hasegawa H, Yuzaki M, Kanaho Y. Neuron. 73(1): 135-48 (2012). 22243752
AxCANCre (RDB01748) The E1 protein of human papillomavirus type 16 is dispensable for maintenance replication of the viral genome. Egawa N, Nakahara T, Ohno S, Narisawa-Saito M, Yugawa T, Fujita M, Yamato K, Natori Y, Kiyono T. J Virol. 86(6): 3276-83 (2012). 22238312
Thermus thermophilus expression plasmid set Crystal structure of hypothetical protein TTHB210, controlled by the ρEE) /anti-ρEE) regulatory system in Thermus thermophilus HB8, reveals a novel homodecamer. Agari Y, Kuramitsu S, Shinkai A. Proteins. 80(3): 958-62 (2012). 22231934
pUC kit EH1 (RDB01344) Growth control of genetically modified cells using an antibody/c-Kit chimera. Kaneko E, Kawahara M, Ueda H, Nagamune T. J Biosci Bioeng. 113(5): 641-6 (2012). 22227120
pBMSA-NP (RDB01972) Heat-shock protein 70 from plant biofactories of recombinant antigens activate multiepitope-targeted immune responses. Buriani G, Mancini C, Benvenuto E, Baschieri S. Plant Biotechnol J. 10(3): 363-71 (2012). 22221920
pco12 EGFR (RDB01276) Surface plasmon resonance-biosensor detects the diversity of responses against epidermal growth factor in various carcinoma cell lines. Hiragun T, Yanase Y, Kose K, Kawaguchi T, Uchida K, Tanaka S, Hide M. Biosens Bioelectron. 32(1): 202-7 (2012). 22204782
Mouse E-cadherin full length cDNA (RDB01184) The differentiation and isolation of mouse embryonic stem cells toward hepatocytes using galactose-carrying substrata. Meng Q, Haque A, Hexig B, Akaike T. Biomaterials. 33(5): 1414-27 (2012). 22118818
MSM Mouse BAC clone Novel regulatory mechanism and functional implication of plasminogen activator inhibitor-1 (PAI-1) expression in CpG-ODN-stimulated macrophages. Thapa B, Kim YH, Kwon HJ, Kim DS. Mol Immunol. 49(4): 572-81 (2012). 22078208
mDEC1-FLAG in pCAGGS (RDB08473) HIF-1α induction suppresses excessive lipid accumulation in alcoholic fatty liver in mice. Nishiyama Y, Goda N, Kanai M, Niwa D, Osanai K, Yamamoto Y, Senoo-Matsuda N, Johnson RS, Miura S, Kabe Y, Suematsu M. J Hepatol. 56(2): 441-7 (2012). 21896344
pCR8/GW/TOPO-UeBgl3A (RDB08966) Identification, cloning, and characterization of β-glucosidase from Ustilago esculenta. Nakajima M, Yamashita T, Takahashi M, Nakano Y, Takeda T. Appl Microbiol Biotechnol. 93(5): 1989-98 (2012). 21850431
pEF-Flag-mSTATY705F (RDB02354) Stat3 inhibition in neural lineage cells. Chiba, T., Mack, L., Delis, N., Brill, B., Groner, B. Hormone Molecular Biology and Clinical Investigation 10 (2): 255-263 (2012).


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2011年

RDB No. Title Journal Author PMID
(RDB 7363) pBluescript SKII+AV1-235-4491 Adeno-associated virus Rep-mediated targeting of integrase-defective retroviral vector DNA circles into human chromosome 19. Biochem Biophys Res Commun. 2011 Nov 22. [Epub ahead of print] Huang, S., Kawabe, Y., Ito, A., Kamihira, M. 22138242
(RDB 1442) pMFGmIL3 Identification and characterization of Hoxa9 binding sites in hematopoietic cells. Blood. 2011 Nov 9. [Epub ahead of print] Huang, Y., Sitwala, K., Bronstein, J., Sanders, D., Dandekar, M., Collins, C., Robertson, G., Macdonald, J., Cezard, T., Bilenky, M., Thiessen, N., Zhao, Y., Zeng, T., Hirst, M., Hero, A., Jones, S., Hess, J.L. 22072553
(RDB 1862) pCALNL5 RB1CC1 suppresses type II collagen synthesis in chondrocytes, and causes dwarfism. J. Biol. Chem., 286 (51): 43925-43932 (2011). Nishimura, I., Chano, T., Kita, H., Matsusue, Y., Okabe, H. 22049074
(RDB 6273) Rat BAC RNB1(RNB1-222L22) Derivation of rat embryonic stem cells and generation of protease-activated receptor-2 knockout rats. Transgenic Res. 2011 Oct 15. [Epub ahead of print] Yamamoto S., Nakata M, Sasada R, Ooshima Y, Yano T, Shinozawa T, Tsukimi Y, Takeyama M, Matsumoto Y, Hashimoto T. 22002084
(RDB 4267) pCMV-SP1 G4-DNA Formation in the HRAS Promoter and Rational Design of Decoy Oligonucleotides for Cancer Therapy. PLoS One. 6 (9): e24421 (2011). Membrino, A., Cogoi, S., Pedersen, E.B., Xodo, L.E. 21931711
(RDB 5699) pGEX-SP1
(RDB 5701) pGEX-hMAZ
(RDB 3219) pCMV-MAZ
(RDB 1748) AxCANCre
Inhibition of Ubiquitin ligase F-box and WD repeat domain-containing 7(alpha) (Fbw7(alpha}) causes hepatosteatosis through the Kruppel-like factor 5 (KLF5)/PPAR(gamma)2 pathway, but not SREBP-1c in mice. J. Biol. Chem., 286 (47): 40835-40846 (2011). Kumadaki, S., Karasawa, T., Matsuzaka, T., Ema, M., Nakagawa, Y., Nakakuki, M., Saito, R., Yahagi, N., Iwasaki, H., Sone, H., Takekoshi, K., Yatoh, S., Kobayashi, K., Takahashi, A., Suzuki, H., Takahashi, S., Yamada, N., Shimano, H. 21911492
(RDB 3021) pCMX-N/RBP-J Wt1a, Foxc1a, and the Notch mediator Rbpj physically interact and regulate the formation of podocytes in zebrafish. Dev. Biol., 358 (2): 318-330 (2011). O’Brien, L.L., Grimaldi, M., Kostun, Z., Wingert, R.A., Selleck, R., Davidson, A.J. 21871448
(RDB 6771) pEF-BOSneo-mNotch1 RAMIC
(RDB 6776) TP1-luc(981-6) (a.k.a. pGa981-6)
(RDB 6088) pEThsJNK1
JNK1 Phosphorylation of Cdt1 Inhibits Recruitment of HBO1 Histone Acetylase and Blocks Replication Licensing in Response to Stress. Mol. Cell., 4 4(1): 62-71 (2011). Miotto, B., Struhl, K. 21856198
(RDB 2443) pCAcc-Luc+ Effect of integrin targeting and PEG shielding on polyplex micelle internalization studied by live-cell imaging. J. Control Release, 156 (3): 364-373 (2011). Mickler, F.M., Vachutinsky, Y., Oba, M., Miyata, K., Nishiyama, N., Kataoka, K., Br?uchle, C., Ruthardt, N. 21843561
(RDB 5595) pC/EBP RE-TK hRluc(F)
(RDB 5658) pC/EBP RE-TK hRluc(R)
Water-Soluble Extract of Pacific Krill Prevents Triglyceride Accumulation in Adipocytes by Suppressing PPARgamma and C/EBPalpha Expression. PLoS One 6 (7): e21952 (2011). Yamada, H., Ueda, T., Yano, A. 21760932
(RDB ) S. pombe A genome wide study in fission yeast reveals nine PPR proteins that regulate mitochondrial gene expression. Nucleic Acids Res., 39 (18): 8029-8041 (2011). Kuhl, I., Dujeancourt, L., Gaisne, M., Herbert, C.J., Bonnefoy, N. 21727087
(RDB 5812) pKM2L-phKIT Direct and differential effects of stem cell factor on the neovascularization activity of endothelial progenitor cells. Cardiovasc Res. 92 (1): 132-140 (2011). Kim, K.L., Meng, Y., Kim, J.Y., Baek, E.J., Suh, W. 21636540
(RDB 1971) pBMSA-PA Anti-influenza activity of marchantins, macrocyclic bisbibenzyls contained in liverworts. PLoS One 6 (5): e19825 Iwai, Y., Murakami, K., Gomi, Y., Hashimoto, T., Asakawa, Y., Okuno, Y., Ishikawa, T., Hatakeyama, D., Echigo, N., Kuzuhara, T. 21625478
(RDB 6519) pREP1-ccdB2 Glucosidase II and N-glycan mannose content regulate the half-lives of monoglucosylated species in vivo. Mol. Biol. Cell, (2011). Stigliano, I.D., Alculumbre, S.G., Labriola, C.A., Parodi, A.J., D’Alessio, C. 21471007
(RDB 5820) S. pombe entry clone(26/D11)
(RDB 1376) pUC-ER6
Circadian transcriptional factor DBP regulates expression of Kiss1 in the anteroventral periventricular nucleus. Mol Cell Endocrinol. 339 (1-2): 90-97 (2011). Xu, Z., Kaga, S., Tsubomizu, J., Fujisaki, J., Mochiduki, A., Sakai, T., Tsukamura, H., Maeda, K., Inoue, K., Adachi, A.A. 21458520
anonymous An expression profile analysis of ES cell-derived definitive endodermal cells and Pdx1-expressing cells. BMC Dev. Biol., 11, 13 (2011). Ogaki, S., Harada, S., Shiraki, N., Kume, K., Kume, S. 21362171
(RDB 3022) pCMX-N/RBP-J (R218H) Regulation of nonclassical fgf1 release and fgf-dependent cell transformation by CBF1-mediated notch signaling. J. Cell. Physiol., 226 (11): 3064-3075 (2011). Kacer, D., McIntire, C., Kirov, A., Kany, E., Roth, J., Liaw, L., Small, D., Friesel, R., Basilico, C., Tarantini, F., Verdi, J., Prudovsky, I. 21302306
(RDB 5547) pKM2L-phUPA Plasminogen activator uPA is a direct transcriptional target of the JAG1-Notch receptor signaling pathway in breast cancer. Cancer Res., 71, 277-286 (2011) . Shimizu, M., Cohen, B., Goldvasser, P., Berman, H., Virtanen, C., Reedijk, M. 21199807
(RDB 1184) Mouse E-cadherin full length cDNA The effect of recombinant E-cadherin substratum on the differentiation of endoderm-derived hepatocyte-like cells from embryonic stem cells. Biomaterials, 32, 2032-2042 (2011). Haque, A., Hexig, B., Meng, Q., Hossain, S., Nagaoka, M., Akaike, T. 21163520
(RDB 5593) pp53-Box RE-TK hRluc(F) RNF43 interacts with NEDL1 and regulates p53-mediated transcription. Biochem. Biophys. Res. Commun., 404 (1): 143-147 (2011). Shinada, K., Tsukiyama, T., Sho, T., Okumura, F., Asaka, M., Hatakeyama, S. 21108931
(RDB 3219) pCMV-MAZ Mechanisms by which Interleukin-6 Regulates Prostate Specific Antigen Gene Expression in Prostate LNCaP Carcinoma Cells. J. Androl. 32 (4): 383-393 (2011). Tsui K.H., Lin Y.F., Chen Y.H., Chang P.L., Juang H.H. 21051589
(RDB 6119) Thermus thermophilus expression plasmid set Crystal structure of hypothetical protein TTHB210, controlled by the σE/anti-σE regulatory system in Thermus thermophilus HB8, reveals a novel homodecamer. Proteins: Structure, Function, and Bioinformatics, (2011), Agari, Y., Kuramitsu, S., Shinkai, A.
(RDB 1184) Mouse E-cadherin full length cDNA Control of singular cell cycle synchronization of mouse ES cells for hepatocyte differentiation on E-cadherin substratum. J. Biotechnol. Biomaterial, 1 (6) (2011). Jovic, D., Haque, A., Exig, B., Nagaoka, m., Akaike, T.
(RDB 1681) pCMV (Hu beta) Ultrasound-mediated interferon β gene transfection inhibits growth of malignant melanoma. Biochem. Biophys. Res. Commun. 411 (1): 137-142 (2011). Yamaguchi, K., Feril, .L.B. Jr., Tachibana, K., Takahashi, A., Matsuo, M., Endo, H., Harada, Y., Nakayama, J.


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2010年

RDB No. Title Journal Author PMID
(RDB 1750) AxCALNLNZ
(RDB 1675) pxCANCre
(RDB 5507) pKM2L-phP53
Stimulation of p53 Transactivation Ability by Nicastrin in Mouse Fibroblasts. SRX Biology, 2010 , Article ID 606391 Koshida, T., Kitagawa, M., Iwase, K., Takiguchi, M., Hiwasa, T.
(RDB 3219) pCMV-MAZ Involvement of ubiquitous and tale transcription factors, as well as liganded RXRα, in the regulation of human SOX2 gene expression in the NT2/D1 embryonal carcinoma cell line. Arch. Biol. Sci., Belgrade, 62, 199-210 (2010). Milena, M., Gordana, N., Natasa, K.G., Krstic, A., Marija, M., Danijela, D., Milena, S.
(RDB 1748) AxCANCre Efficient Gene Transduction in HER2-Expressing Cells by Two Recombinant Adenovirus Vectors with HER2 Promotor and Cre/loxP System. Hirosaki Med.J., 61, 26―34 (2010). Nodagashira T., Odagiri H., Ikenaga S.K., Murayama M., Sato T., Hakamada K.
(RDB 2453) AxCA Luc+ Identification of dynamin-2-mediated endocytosis as a new target of osteoporosis drugs, bisphosphonates. Mol. Pharmacol., 77, 262-269 (2010). Masaike Y., Takagi T., Hirota M., Yamada J., Ishihara S., Yung T.M., Inoue T., Sawa C., Sagara H., Sakamoto S., Kabe Y., Takahashi Y., Yamaguchi Y., Handa H. 19903825
(RDB 1862) pCALNL5 Mature acinar cells are refractory to carcinoma development by targeted activation of Ras oncogene in adult rats. Cancer Sci., 101, 341-346 (2010). Tanaka H., Fukamachi K., Futakuchi M., Alexander D.B., Long N., Tamamushi S., Minami K., Seino S., Ohara H., Joh T., Tsuda H. 19917056
(RDB 6284) T. thermophilus HB8 disruption plasmid(TTHA1619) N7-Methylguanine at position 46 (m7G46) in tRNA from Thermus thermophilus is required for cell viability at high temperatures through a tRNA modification network. Nucleic Acids Res., 38, 942-957 (2010). Tomikawa C., Yokogawa T., Kanai T., Hori H. 19934251
(RDB 1890) pRx-crmA-bsr Tumor necrosis factor-related apoptosis-inducing ligand 1 (TRAIL1) enhances the transition of red blood cells from the larval to adult type during metamorphosis in Xenopus. Blood, 115, 850-859 (2010). Tamura K., Mawaribuchi S., Yoshimoto S., Shiba T., Takamatsu N., Ito M. 19965624
(RDB 1675) pxCANCre An accumulative site-specific gene integration system using Cre recombinase-mediated cassette exchange. Biotechnol. Bioeng., 105, 1106-1114 (2010). Kameyama Y., Kawabe Y., Ito A., Kamihira M. 19998287
(RDB 4214) MSM Mouse BAC clone() Transcriptional regulation of cGMP-dependent protein kinase II (cGK-II) in chondrocytes. Biosci. Biotechnol. Biochem., 74 (1), 44-49 (2010). Yuasa, K., Uehara, S., Nagahama, M., Tsuji, A. 20057151
(RDB 2934) hTRAIL/pMKITneo Human CD34+ cells engineered to express membrane-bound tumor necrosis factor-related apoptosis-inducing ligand target both tumor cells and tumor vasculature. Blood, 115 (11), 2231-2240 (2010). Lavazza, C., Carlo-Stella, C., Giacomini, A., Cleris, L., Righi, M., Sia, D., Di Nicola, M., Magni, M., Longoni, P., Milanesi, M., Francolini, M., Gloghini, A., Carbone, A., Formelli, F., Gianni, A.M. 20075160
(RDB 1675) pxCANCre Integrin alpha5beta1 is necessary for regulation of radial migration of cortical neurons during mouse brain development. Eur. J. Neurosci., 31, 399-409, (2010). Marchetti G., Escuin S., van der Flier A., De Arcangelis A., Hynes RO., Georges-Labouesse E. 20105241
(RDB 2443) pCAcc-Luc+ Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1 plasmid DNA carried by RGD-modified crosslinked polyplex micelles. J. Control. Release (2010). Vachutinsky Y., Oba M., Miyata K., Hiki S., Kano M.R., Nishiyama N., Koyama H., Miyazono K., Kataoka K. 20138936
(RDB 3486) pAxCALNLheIF2 alpha(forward) Maintaining ATP levels via the suppression of PERK-mediated rRNA synthesis at ER stress. Biochem. Biophys. Res. Commun., 394, 42-47 (2010). Okamoto A., Koike M., Yasuda K., Kakizuka A. 20171949
(RDB 2443) pCAcc-Luc+ Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble flt-1. Mol. Pharm. 7 (2), 501-509 (2010). Oba M, Vachutinsky Y, Miyata K, Kano MR, Ikeda S, Nishiyama N, Itaka K, Miyazono K, Koyama H, Kataoka K. 20178335
(RDB 6142) pDUAL-FFH1c A novel yeast cell-based screen identifies flavone as a tankyrase inhibitor. Biochem. Biophys. Res. Commun., 394, 569-573 (2010). Yashiroda, Y., Okamoto, R., Hatsugai, K., Takemoto, Y., Goshima, N., Saito, T., Hamamoto, M., Sugimoto, Y., Osada, H., Seimiya, H., Yoshida, M. 20214890
(RDB 4214) MSM Mouse BAC clone(MSMg01-318O12) Genetic variation of melatonin productivity in laboratory mice under domestication. Proc. Natl. Acad. Sci. U S A., 107, 6412-6417 (2010). Kasahara T., Abe K., Mekada K., Yoshiki A., Kato T. 20308563
(RDB 1764) RAT GATA-GT2 Myogenic differentiation in atrium-derived adult cardiac pluripotent cells and the transcriptional regulation of GATA4 and myogenin on ANP promoter. Genes Cells, 15, 439-453 (2010). Kamrul Hasan M., Komoike Y., Tsunesumi SI., Nakao R., Nagao H., Matsuoka R., Kawaguchi N. 20384792
(RDB 6107) S. pombe YFH-tag clone() Specific splicing defects in S. pombe carrying a degron allele of the Survival of Motor Neuron gene. EMBO J. 29 (11): 1817-1829 (2010). Campion Y., Neel H., Gostan T., Soret J., Bordonne R. 20400941
(RDB 5701) pGEX-hMAZ
(RDB 3219) pCMV-MAZ
The KRAS promoter responds to Myc-associated zinc finger and poly(ADP-ribose) polymerase 1 proteins, which recognize a critical quadruplex-forming GA-element. J. Biol. Chem., 285, 22003-22016 (2010). Cogoi S., Paramasivam M., Membrino A., Yokoyama KK., Xodo L.E. 20457603
(RDB 6284) T. thermophilus HB8 disruption plasmid(TTHB178)
(RDB 3436) pUC18-HTK (with promoter)
A novel single-stranded DNA-specific 3′-5′ exonuclease, Thermus thermophilus exonuclease I, is involved in several DNA repair pathways. Nucleic Acids Res., 38 (17), 5692-5705 (2010). Shimada, A., Masui, R., Nakagawa, N., Takahata, Y., Kim, K., Kuramitsu, S., Fukui, K. 20457749
(RDB 5723) NIA 15K Mouse cDNA Clone Identification of DAF1/CD55, a novel definitive endoderm marker. Cell Struct. Funct., 35 (2), 73-80 (2010). Shiraki, N., Harada, S., Ogaki, S., Kume, K., Kume, S. 20526042
(RDB 1969) pBMSA-PB2
(RDB 1971) pBMSA-PA
Anti-influenza activity of phenethylphenylphthalimide analogs derived from thalidomide. Bioorg. Med. Chem., 18, 5379-5390 (2010). Iwai Y., Takahashi H., Hatakeyama D., Motoshima K., Ishikawa M., Sugita K., Hashimoto Y., Harada Y., Itamura S., Odagiri T., Tashiro M., Sei Y., Yamaguchi K., Kuzuhara T. 20538468
(RDB 6142) pDUAL-FFH1c Marine antifungal theonellamides target 3beta-hydroxysterol to activate Rho1 signaling. Nat. Chem. Biol., 6, 519-526 (2010). Nishimura, S., Arita, Y., Honda, M., Iwamoto, K., Matsuyama, A., Shirai, A., Kawasaki, H., Kakeya, H., Kobayashi, T., Matsunaga, S., Yoshida, M. 20543850
(RDB 5514) pKM2L-phMK Molecular engineering and validation of an oncolytic herpes simplex virus type 1 transcriptionally targeted to midkine-positive tumors. J. Gene. Med., 12, 613-623 (2010). Maldonado AR., Klanke C., Jegga AG., Aronow BJ., Mahller YY., Cripe TP., Crombleholme TM. 20603890
(RDB 1801) RBP-J Osteogenic differentiation of mouse mesenchymal progenitor cell, Kusa-A1 is promoted by mammalian transcriptional repressor Rbpj. Biochem. Biophys. Res. Commun., 400, 39-45 (2010). Wang S., Kawashima N., Sakamoto K., Katsube K., Umezawa A., Suda H. 20691157
(RDB 5820) S. pombe entry clone(02-G12)
(RDB 5820) S. pombe entry clone(18-E01)
Reorganization of the growth pattern of Schizosaccharomyces pombe in invasive filament formation. Eukaryot. Cell, 9, 1788-1797 (2010). Dodgson, J., Brown, W., Rosa, C.A., Armstrong, J. 20870879
(RDB 7499) Aeropyrum pernix JCM 9820T Structural basis for mRNA surveillance by archaeal Pelota and GTP-bound EF1α complex. Proc. Natl. Acad. Sci. U S A., 107 (41): 17575-17579 (2010). Kobayashi, K., Kikuno, I., Kuroha, K., Saito, K., Ito, K., Ishitani, R., Inada, T., Nureki, O. 20876129
(RDB 7573) B6N Mouse BAC clone()
(RDB 4214) MSM Mouse BAC clone()
Rapid bacterial artificial chromosome modification for large-scale mouse transgenesis. Nat. Protoc., 5 (10), 1678-1696 (2010). Gong, S., Kus, L., Heintz, N. 20885380
(RDB 2443) pCAcc-Luc+ Polyplex micelles prepared from omega-cholesteryl PEG-polycation block copolymers for systemic gene delivery. Biomaterials., 32 (2): 652-663 (2010) Oba M., Miyata K., Osada K., Christie R.J., Sanjoh M., Li W., Fukushima S., Ishii T., Kano M.R., Nishiyama N., Koyama H., Kataoka K. 20932567
(RDB 7499) Aeropyrum pernix JCM 9820T Omnipotent role of archaeal elongation factor 1 alpha (EF1α in translational elongation and termination, and quality control of protein synthesis. Proc. Natl. Acad. Sci. U S A., 107 (45): 19242-19247 (2010). Saito, K., Kobayashi, K., Wada, M., Kikuno, I., Takusagawa, A., Mochizuki, M., Uchiumi, T., Ishitani, R., Nureki, O., Ito, K. 20974926


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2009年

RDB No. Title Journal Author PMID
(RDB 1675) pxCANCre Construction of a multi-functional helper-dependent adenovirus based system for cancer gene therapy. Asian Pac. J. Cancer Prev., 10, 939-960 (2009). Long N., Hardiville S., Pierce A., Fukamachi K., Futakuchi M., Alexander D.B., Shirai T., Tsuda H. 20104994
(RDB 1971) pBMSA-PA Green tea catechins inhibit the endonuclease activity of influenza A virus RNA polymerase. PLoS Curr., 1, RRN1052 (2009). Kuzuhara T., Iwai Y., Takahashi H., Hatakeyama D., Echigo N. 20025206
(RDB 1748) AxCANCre Novel immortalized human fetal liver cell line, cBAL111, has the potential to differentiate into functional hepatocytes. BMC Biotechnol., 9: 89 (2009). Deurholt T., van Til N.P., Chhatta A.A., ten Bloemendaal L., Schwartlander R., Payne C., Plevris J.N., Sauer I.M., Chamuleau R.A., Elferink R.P., Seppen J., Hoekstra R. 19845959
(RDB 1862) pCALNL5 An animal model of preclinical diagnosis of pancreatic ductal adenocarcinomas. Biochem. Biophys. Res. Commun., 390, 636-641 (2009). Fukamachi K., Tanaka H., Hagiwara Y., Ohara H., Joh T., Iigo M., Alexander D.B., Xu J., Long, N., Takigahira M., Yanagihara K., Hino O., Saito I., Tsuda H. 19818733
(RDB 6151) pDUAL-YFH1c
(RDB 6519) pREP1-ccdB2
(RDB 5820) S. pombe entry clone(26/D11 (SPCC825.02))
Glucosidase II beta subunit modulates N-glycan trimming in fission yeasts and mammals. Mol. Biol. Cell, 20, 3974-3984 (2009). Stigliano I.D., Caramelo J.J., Labriola C.A., Parodi A.J., D’Alessio C. 19605557
(RDB 1276) pco12 EGFR Selection and growth regulation of genetically modified cells with hapten-specific antibody/receptor tyrosine kinase chimera. Biotechnol. Progr., 25, 1138-1145 (2009). Tanaka, K., Kawahara, M., Ueda, H., Nagamune, T. 19569211
(RDB 1126) pSVtsA58 ori (-) Establishment of a cell line derived from a mouse fetal liver that has the characteristic to promote the hepatic maturation of mouse embryonic stem cells by a coculture method. Tissue Eng. Part A., 15, 3847-3856 (2009). Fukumitsu K., Ishii T., Yasuchika K., Amagai Y., Kawamura-Saito M., Kawamoto T., Kawase E., Suemori H., Nakatsuji N., Ikai I., Uemoto S. 19558317
(RDB 4214) MSM Mouse BAC clone() Visualization of chemokine receptor activation in transgenic mice reveals peripheral activation of CCR2 receptors in states of neuropathic pain. J. Neurosci., 29, 8051-8062 (2009). Jung H., Bhangoo S., Banisadr G., Freitag C., Ren D., White F.A., Miller R.J. 19553445
(RDB 1372) Human MDR1 cDNA Construction of a model cell line for the assay of MDR1 (multi drug resistance gene-1) substrates/inhibitors using HeLa cells. Pharmazie, 64, 296-300 (2009). Kugawa F., Suzuki T., Miyata M., Tomono K., Tamanoi F. 19530439
(RDB 1687) pCM-hGM Quick method of multimeric protein production for biologically active substances such as human GM-CSF (hGM-CSF). Biochem. Biophys. Res. Commun., 386, 40-44 (2009). Shinya E., Owaki A., Norose Y., Sato S., Takahashi H. 19497303
(RDB 5610) pISRE-TK hRluc(F)
(RDB 5624) pGAS RE-TK hRluc(F)
(RDB 5616) pSTAT RE-TK hRluc(F)
Chondromodulin-1 directly suppresses growth of human cancer cells. BMC Cancer, 9, 166 (2009). Mera H., Kawashima H., Yoshizawa T., Ishibashi O., Ali M.M., Hayami T., Kitahara H., Yamagiwa H., Kondo N., Ogose A., Endo N., Kawashima H. 19480713
(RDB 4214) MSM Mouse BAC clone() Usp46 is a quantitative trait gene regulating mouse immobile behavior in the tail suspension and forced swimming tests. Nat. Genet., 41 (6): 688-695 (2009). Tomida S., Mamiya T., Sakamaki H., Miura M., Aosaki T., Masuda M., Niwa M., Kameyama T., Kobayashi J., Iwaki Y., Imai S., Ishikawa A., Abe K., Yoshimura T., Nabeshima T., Ebihara S. 19465912
(RDB 5463) pBC-H2.6 Detection of plasmid-mediated quinolone resistance genes in clinical isolates of Enterobacter spp. in Spain. J. Clin. Microbiol., 47, 2033-2039 (2009). Cano M.E., Rodriguez-Martinez J.M., Aguero J., Pascual A., Calvo J., Garcia-Lobo J.M., Velasco C., Francia M.V., Martinez-Martinez L. 19386836
(RDB 4395) pENTR4-H1 The orphan nuclear receptor RORalpha restrains adipocyte differentiation through a reduction of C/EBPbeta activity and perilipin gene expression. Mol. Endocrinol., 23, 759-771 (2009). Ohoka, N., Kato. S., Takahashi. Y., Hayashi, H., Sato, R. 19324970
(RDB 2139) D-HA Regulation of intestinal Cl-/HCO3- exchanger SLC26A3 by intracellular pH. Am. J. Physiol. Cell Physiol., 296, C1279-1290 (2009). Hayashi, H., Suruga, K., Yamashita, Y. 19321737
(RDB 1735) Ax1 CI-mIGIF Cytosine deaminase-uracil phosphoribosyltransferase and interleukin (IL)-12 and IL-18: a multimodal anticancer interface marked by specific modulation in serum cytokines. Clin. Cancer Res., 15, 2323-2334 (2009). Khatri A., Husaini Y., Ow K., Chapman J., Russell P.J. 19318483
(RDB 1675) pxCANCre Introduction of tau mutation into cultured Rat1-R12 cells by gene targeting, using recombinant adeno-associated virus vector. Cell. Mol. Neurobiol., 29, 699-705 (2009). Shimada H., Numazawa K., Sasaki T., Kato N., Ebisawa T. 19305950
(RDB 1476) pBluescript SKII+mIL10 Viral and murine interleukin-10 are correctly processed and retain their biological activity when produced in tobacco. BMC Biotechnol., 9: 22 (2009). Bortesi L., Rossato M., Schuster F., Raven N., Stadlmann J., Avesani L., Falorni A., Bazzoni F., Bock R., Schillberg S., Pezzotti M. 19298643
(RDB 2199) AxCAhFLIP Adenovirus-mediated gene expression of the human c-FLIP(L) gene protects pig islets against human CD8(+) cytotoxic T lymphocyte-mediated cytotoxicity. Transplant. Proc., 41, 319-322 (2009). Tanemura M., Saga A., Kawamoto K., Machida T., Deguchi T., Nishida T., Sawa Y., Doki Y., Mori M., Ito T. 19249545
(RDB 1748) AxCANCre Abnormal DNA methyltransferase expression in mouse germline stem cells results in spermatogenic defects. Biol. Reprod., 81, 155-164 (2009). Takashima, S., Takehashi, M., Lee, J., Chuma, S., Okano, M., Hata, K., Suetake, I., Nakatsuji, N., Miyoshi H, Tajima S, Tanaka Y, Toyokuni S, Sasaki, H., Kanatsu-Shinohara, M., Shinohara, T. 19228594
(RDB 1969) pBMSA-PB2 Crystallization and X-ray diffraction analysis of the RNA primer/promoter-binding domain of influenza A virus RNA-dependent RNA polymerase PB2. Acta Crystallogr. Sect. F. Struct. Biol. Cryst. Commun., 65 (Pt 2): 144-146 (2009). Kuzuhara T., Kise D., Yoshida H., Horita T., Murazaki Y., Utsunomiya H., Tsuge H. 19194006
(RDB 1969) pBMSA-PB2 Structural basis of the influenza A virus RNA polymerase PB2 RNA-binding domain containing the pathogenicity-determinant lysine 627 residue. J. Biol. Chem. 284, 6855-6860 (2009) Kuzuhara T., Kise D., Yoshida H., Horita T., Murazaki Y., Nishimura A., Echigo N., Utsunomiya H., Tsuge H. 19144639
(RDB 4214) MSM Mouse BAC clone() Transcriptional regulation of fibrillin-2 gene by E2F family members in chondrocyte differentiation. J. Cell. Biochem. 106 (4): 580-588 (2009). Yanagino, T., Yuasa, K., Nagahama, M., Matsuda, Y., Tsuji, A. 19142862
(RDB 6119) Thermus thermophilus expression plasmid set Thermus thermophilus-derived protein tags that aid in preparation of insoluble viral proteins. Anal. Biochem., 385, 278-285 (2009). Kondo N., Ebihara A., Ru H., Kuramitsu S., Iwamoto A., Rao Z., Matsuda Z. 19084492
(RDB 5463) pBC-H2.6 Detection and genetic characterisation of qnrB in hospital isolates of Klebsiella pneumoniae in Singapore. Int. J. Antimicrob. Agents., 33, 177-180 (2009). Teo, J.W., Ng, K.Y., Lin, R.T. 18993034
(RDB 1579) AxCEAprZ E1A, E1B double-restricted replicative adenovirus at low dose greatly augments tumor-specific suicide gene therapy for gallbladder cancer. Cancer Gene Ther., 16, 126-136 (2009). Fukuda K., Abei M., Ugai H., Kawashima R., Seo E., Wakayama M., Murata T., Endo S., Hamada H., Hyodo I., Yokoyama K.K. 18818710
(RDB 1487) pBluescript SKII+mbFGF Regulation of exogenous bFGF gene mediated by recombinant adeno-associated virus in vitro Frontiers of Medicine in China, 3, 158-163 (2009). Song, K., Rao, N., Chen, M., Cao, Y.


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2008年

RDB No. Title Journal Author PMID
(RDB 2443) pCAcc-Luc+ Polyplex micelles with cyclic RGD peptide ligands and disulfide cross-links directing to the enhanced transfection via controlled intracellular trafficking. Mol. Pharm., 5, 1080-1092 (2008). Oba M., Aoyagi K., Miyata K., Matsumoto Y., Itaka K., Nishiyama N., Yamasaki Y., Koyama H., Kataoka K. 19434856
(RDB 5463) pBC-H2.6 qnrD, a novel gene conferring transferable quinolone resistance in Salmonella enterica serovar Kentucky and Bovismorbificans strains of human origin. Antimicrob. Agents. Chemother., 53, 603-608 (2008). Cavaco L.M., Hasman H., Xia S., Aarestrup F.M. 19029321
(RDB 1184) Mouse E-cadherin full length cDNA Interaction of KLRG1 with E-cadherin: new functional and structural insights. Eur. J. Immunol., 38, 3354-3364 (2008). Rosshart S., Hofmann M., Schweier O., Pfaff A.K., Yoshimoto K., Takeuchi T., Molnar E., Schamel W.W., Pircher H. 19009530
(RDB 1745) AxCALacZ Differentiation of mouse hepatic progenitor cells induced by hepatocyte nuclear factor-4 and cell transplantation in mice with liver fibrosis. Transplantation, 86, 1178-1186 (2008). Suetsugu A., Nagaki M., Aoki H., Motohashi T., Kunisada T., Moriwaki H. 19005397
(RDB 1862) pCALNL5 Epigenetic regulation of neural cell differentiation plasticity in the adult mammalian brain. Proc. Natl. Acad. Sci. U. S. A., 105, 18012-18017 (2008). Kohyama J., Kojima T., Takatsuka E., Yamashita T., Namiki J., Hsieh J., Gage F.H., Namihira M., Okano H., Sawamoto K., Nakashima K. 19004774
(RDB 1748) AxCANCre Homing of mouse spermatogonial stem cells to germline niche depends on beta1-integrin. Cell Stem Cell, 3 (5): 533-542 (2008). Kanatsu-Shinohara, M., Takehashi, M., Takashima, S., Lee, J., Morimoto, H., Chuma, S., Raducanu, A., Nakatsuji, N., F?ssler, R., Shinohara, T. 18983968
(RDB 3452) p3AP1 (PMA) RE-TK hRluc(F) p63/p51-induced onset of keratinocyte differentiation via the c-Jun N-terminal kinase pathway is counteracted by keratinocyte growth factor. J. Biol. Chem., 283, 34241-34249 (2008). Ogawa E., Okuyama R., Egawa T., Nagoshi H., Obinata M., Tagami H., Ikawa S., Aiba S. 18849344
(RDB 2547) AxCAHSVtk
(RDB 1745) AxCALacZ
(RDB 1746) Ax1w1
(RDB 1578) AxCEAprTK
(RDB 1038) pUCAlu
Involvement of human ORC and TRF2 in pre-replication complex assembly at telomeres. Genes Cells, 13, 1045-1059 (2008). Tatsumi Y., Ezura K., Yoshida K., Yugawa T., Narisawa-Saito M., Kiyono T., Ohta S., Obuse C., Fujita M. 18761675
(RDB 2774) AxCArJunB (forward) JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells. PLoS One., 3, e3030 (2008). Gurzov E.N., Ortis F., Bakiri L., Wagner E.F, Eizirik,D.L. 18716665
(RDB 1678) pAxCAwt Ramified microglial cells promote astrogliogenesis and maintenance of neural stem cells through activation of Stat3 function. FASEB J., 22, 3866-3877 (2008). Zhu P., Hata R., Cao F., Gu F., Hanakawa Y., Hashimoto K., Sakanaka M. 18685078
(RDB 3459) p3CRE RE-TK hRluc IRF2-binding protein-1 is a JDP2 ubiquitin ligase and an inhibitor of ATF2-dependent transcription. FEBS Lett., 582, 2833-2837 (2008). Kimura M. 18671972
(RDB 1184) Mouse E-cadherin full length cDNA Enhancement of cell function through heterotypic cell-cell interactions using E-cadherin-expressing NIH3T3 cells. J. Biosci. Bioeng., 105, 679-682 (2008). Ito A., Kiyohara T., Kawabe Y., Ijima H., Kamihira M. 18640611
(RDB 1184) Mouse E-cadherin full length cDNA Design of the artificial acellular feeder layer for the efficient propagation of mouse embryonic stem cells. J. Biol. Chem., 283, 26468-26476 (2008). Nagaoka M., Hagiwara Y., Takemura K., Murakami Y., Li J., Duncan S.A., Akaike T. 18614540
(RDB 1201) pIL-2R gamma 2 Selective expansion of genetically modified T cells using an antibody/interleukin-2 receptor chimera. J. Immunol. Methods, 337, 16-23(2008). Sogo T., Kawahara M., Tsumoto K., Kumagai I., Ueda H., Nagamune T. 18589435
(RDB 1126) pSVtsA58 ori (-) Different initial steps of apoptosis induced by two types of antineoplastic drugs. Biochem. Pharmacol., 76, 303-311 (2008). Takagi Y., Hidaka M., Sanada M., Yoshida H., Sekiguchi M. 18573489
(RDB 1198) ETR103 Covalent split protein fragment-DNA hybrids generated through N-terminus-specific modification of proteins by oligonucleotides. Org. Biomol. Chem., 6, 2187-2194 (2008). Takeda S., Tsukiji S., Ueda H., Nagamune T. 18528581
(RDB 1195) Rat TGF beta 1 cDNA Expression of transforming growth factor-beta1 and connective tissue growth factor in the capsule in a rat immobilized knee model. Upsala. J. Med. Sci., 113, 221-234 (2008). Hagiwara Y., Chimoto E., Takahashi I., Ando A., Sasano Y., Itoi E. 18509817
(RDB 1785) pcDNA3-XPF Repair of 2′-C-cyano-2′-deoxy-1-beta-D-arabino-pentofuranosylcytosine-induced DNA single-strand breaks by transcription-coupled nucleotide excision repair. Cancer Res., 68, 3881-3889 (2008). Wang Y., Liu X., Matsuda A., Plunkett W. 18483273
(RDB 3021) pCMX-N/RBP-J Zfp64 participates in Notch signaling and regulates differentiation in mesenchymal cells. J. Cell Sci., 121, 1613-1623 (2008). Sakamoto K., Tamamura Y., Katsube K., Yamaguchi A. 18430783
(RDB 1372) Human MDR1 cDNA Functional evaluation of polymorphisms in the human ABCB1 gene and the impact on clinical responses of antiepileptic drugs. Pharmacogenet. Genomics, 18, 390-402 (2008). Hung C.C., Chen C.C., Lin C.J., Liou H.H. 18408562
(RDB 1862) pCALNL5 Oocyte-specific overexpression of mouse bone morphogenetic protein-15 leads to accelerated folliculogenesis and an early onset of acyclicity in transgenic mice. Endocrinology, 149, 2807-2815 (2008). McMahon, H.E., Hashimoto, O., Mellon, P.L., Shimasaki, S. 18308851
(RDB 4778) pGST-mmJDP2_T148A
(RDB 6216) pET_His-hsJDP2
(RDB 6321) pET_HisFLAG-hsATF-2
(RDB 6211) pT7Tet1
(RDB 6793) H3002E12
(RDB 4757) pGST-mmJDP2_full
Phosphorylation of two eukaryotic transcription factors, Jun dimerization protein 2 and activation transcription factor 2, in Escherichia coli by Jun N-terminal kinase 1. Anal. Biochem., 376, 115-121 (2008). Murata T., Shinozuka Y., Obata Y., Yokoyama K.K. 18307971
(RDB 5463) pBC-H2.6 Plasmid-mediated qepA gene among Escherichia coli clinical isolates from Japan. Antimicrob. Agents Chemother., 52, 1564-1566 (2008). Yamane K., Wachino J., Suzuki S., Arakawa Y. 18285488
(RDB 1198) ETR103 Dimerization-based homogeneous fluorosensor proteins for the detection of specific dsDNA. Biosens. Bioelectron., 23, 1266-1271 (2008). Yoshitake K., Waki S., Ueda H. 18178076
(RDB 4267) pCMV-SP1
(RDB 3219) pCMV-MAZ
Characterization of a neuregulin-1 gene promoter: positive regulation of type I isoforms by NF-kappaB. Biochim. Biophys. Acta – Gene Regul. Mech., 1779, 139-144 (2008). Frensing T., Kaltschmidt C., Schmitt-John T. 18082154
(RDB 1524) pCAhMCSF Identification of angiogenin as the osteoclastic bone resorption-inhibitory factor in bovine milk. Bone, 42, 380-387 (2008). Morita Y., Matsuyama H., Serizawa A., Takeya T., Kawakami H. 18055286
(RDB 1410) AxCAmIL10 Interleukin-10 gene transfer to peritoneal mesothelial cells suppresses peritoneal dissemination of gastric cancer cells due to a persistently high concentration in the peritoneal cavity. Cancer Gene Ther., 15, 51-59 (2008). Tanaka F., Tominaga K., Shiota M., Ochi M., Kuwamura H., Tanigawa T., Watanabe T., Fujiwara Y., Oshitani N., Higuchi K., Iwao H., Arakawa T. 17992202
(RDB 4214) MSM Mouse BAC clone() Monocyte chemoattractant protein-1 functions as a neuromodulator in dorsal root ganglia neurons. J. Neurochem., 104, 254-263 (2008). Jung H., Toth P.T., White F.A., Miller R.J. 17944871


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2007年

RDB No. Title Journal Author PMID
(RDB 4214) MSM Mouse BAC clone(MSMg01-379H11)
(RDB 4214) MSM Mouse BAC clone(MSMg01-090M04)
(RDB 4214) MSM Mouse BAC clone(MSMg01-528J16)
(RDB 4214) MSM Mouse BAC clone(MSMg01-412N17)
(RDB 4214) MSM Mouse BAC clone(MSMg01-342I20)
(RDB 4214) MSM Mouse BAC clone(MSMg01-121H09)
Emergence of complex rearrangements at translocation breakpoints in a transgenic mouse; implications for mechanisms involved in the formation of chromosome rearrangements. Cytogenet. Genome Res., 119, 83-90 (2007). Kasai F., Yoshihara M., Matsukuma S., O’Brien P., Ferguson-Smith M.A. 18160786
(RDB 1171) pKCR. Tac-2A A dileucine motif in its cytoplasmic domain directs beta-catenin-uncoupled E-cadherin to the lysosome. J. Cell Sci., 120, 4395-4406 (2007). Miyashita Y., Ozawa M. 18057030
(RDB 2013) pAxCAhPTEN1 Transduction of phosphatase and tensin homolog deleted on chromosome 10 into eosinophils attenuates survival, chemotaxis, and airway inflammation. J. Immunol., 179, 8105-8111 (2007). Adachi T., Hanaka S., Masuda T., Yoshihara H., Nagase H., Ohta K. 18056352
(RDB 1746) Ax1w1 Thrombin-induced cell proliferation and platelet-derived growth factor-AB release from A172 human glioblastoma cells. J. Thromb. Haemost., 5, 2219-2226 (2007). Hayakawa Y., Kurimoto M., Nagai, S., Kurosaki K., Tsuboi Y., Hamada H., Hayashi N., Endo S. 17958740
(RDB 5974) pGEX-MAZ-delta34
(RDB 5701) pGEX-hMAZ
Transcriptional regulation of human eosinophil RNases by an evolutionary- conserved sequence motif in primate genome. BMC Mol. Biol., 8:89 (2007). Wang H.Y., Chang H.T., Pai T.W., Wu C.I., Lee Y.H., Chang Y.H., Tai H.L., Tang C.Y., Chou W.Y., Chang M.D. 17927842
(RDB 2203) AxCMTK/R
(RDB 1737) Ax1 CMhIL4
Expression of pIX gene induced by transgene promoter: possible cause of host immune response in first-generation adenoviral vectors. Hum. Gene Ther., 18, 925-936 (2007). Nakai M., Komiya K., Murata M., Kimura T., Kanaoka M., Kanegae Y., Saito I. 17907966
(RDB 5463) pBC-H2.6 Plasmid-mediated quinolone resistance determinant qnrS1 detected in Salmonella enterica serovar Corvallis strains isolated in Denmark and Thailand. J. Antimicrob. Chemother., 60, 704-706 (2007). Cavaco L.M., Hendriksen R.S., Aarestrup F.M. 17635876
(RDB 5610) pISRE-TK hRluc(F)
(RDB 5624) pGAS RE-TK hRluc(F)
(RDB 5616) pSTAT RE-TK hRluc(F)
PIASxbeta is a key regulator of osterix transcriptional activity and matrix mineralization in osteoblasts. J. Cell Sci., 120 (Pt 15), 2565-2573 (2007). Ali M.M., Yoshizawa T., Ishibashi O., Matsuda A., Ikegame M., Shimomura J., Mera H., Nakashima K., Kawashima H. 17623776
(RDB 2443) pCAcc-Luc+ Cyclic RGD peptide-conjugated polyplex micelles as a targetable gene delivery system directed to cells possessing alphavbeta3 and alphavbeta5 integrins. Bioconjug. Chem., 18, 1415-1423 (2007). Oba M., Fukushima S., Kanayama N., Aoyagi K., Nishiyama N., Koyama H., Kataoka K. 17595054
(RDB 1749) AxCANLacZ
(RDB 1748) AxCANCre
Adipose tissue-specific inactivation of the retinoblastoma protein protects against diabesity because of increased energy expenditure. Proc. Natl. Acad. Sci. U S A., 104, 10703-10708 (2007). Dali-Youcef N., Mataki C., Coste A., Messaddeq N., Giroud S., Blanc S., Koehl C., Champy M.F., Chambon P., Fajas L., Metzger D., Schoonjans K., Auwerx J. 17556545
(RDB 1745) AxCALacZ
(RDB 1746) Ax1w1
(RDB 2194) AxCAZ3-F/RGD
E1A, E1B double-restricted adenovirus with RGD-fiber modification exhibits enhanced oncolysis for CAR-deficient biliary cancers. Clin. Cancer Res., 13, 3043-3050 (2007). Wakayama M., Abei M., Kawashima R., Seo E., Fukuda K., Ugai H., Murata T., Tanaka N., Hyodo I., Hamada H., Yokoyama K.K. 17505007
(RDB 1745) AxCALacZ JDP2 suppresses adipocyte differentiation by regulating histone acetylation. Cell Death Differ., 14, 1398-1405 (2007). Nakade K., Pan J., Yoshiki A., Ugai H., Kimura M., Liu B., Li H., Obata Y., Iwama M., Itohara S., Murata T., Yokoyama K.K. 17464331
(RDB 1126) pSVtsA58 ori (-) Identification of genetic networks involved in the cell growth arrest and differentiation of a rat astrocyte cell line RCG-12. J. Cell. Biochem., 102, 1472-1485 (2007). Takasaki I., Takarada S., Fukuchi M., Yasuda M., Tsuda M., Tabuchi Y. 17440958
(RDB 1591) pAxCACD Strong enhancement of recombinant cytosine deaminase activity in Bifidobacterium longum for tumor-targeting enzyme/prodrug therapy. Biosci. Biotechnol. Biochem., 71, 874-883 (2007). Hamaji Y, Fujimori M, Sasaki T, Matsuhashi H, Matsui-Seki K, Shimatani-Shibata Y, Kano Y, Amano Y, Taniguchi S. 17420581
(RDB 1870) pCAZ 2 The administration of naked plasmid DNA into the liver induces antitumor innate immunity in a murine liver metastasis model. J. Gene Med., 9, 299-307 (2007). Yonenaga Y., Mori A., Fujimoto A., Nagayama S., Tachibana T., Onodera H., Uemoto S. 17397091
(RDB 1749) AxCANLacZ
(RDB 1748) AxCANCre
Adenovirus-mediated gene delivery into mouse spermatogonial stem cells. Proc. Natl. Acad. Sci. U. S. A., 104 (8): 2596-2601 (2007). Takehashi, M., Kanatsu-Shinohara, M., Inoue, K., Ogonuki, N., Miki, H., Toyokuni, S, Ogura A., Shinohara, T. 17299052
(RDB 5463) pBC-H2.6 First detection of plasmid-mediated quinolone resistance (qnrA and qnrS) in Escherichia coli strains isolated from humans in Scandinavia. J. Antimicrob. Chemother., 59, 804-805 (2007). Cavaco L.M., Hansen D.S., Friis-Moller A., Aarestrup F.M., Hasman H., Frimodt-Moller N. 17284539
(RDB 2012) AxCAhPTEN1 PTEN reduces cuff-induced neointima formation and proinflammatory cytokines. Am. J. Physiol. Heart Circ. Physiol., 292, 2824-2831 (2007). S. Koide, M. Okazaki, M. Tamura, K. Ozumi, H. Takatsu, F. Kamezaki, A. Tanimoto, H. Tasaki, Y. Sasaguri, Y. Nakashima, Y. Otsuji 17277022
(RDB 1748) AxCANCre Ku70/80 modulates ATM and ATR signaling pathways in response to DNA double strand breaks. J. Biol. Chem., 282, 10138-10145 (2007). Tomimatsu N., Tahimic C.G., Otsuki A., Burma S., Fukuhara A., Sato K., Shiota G., Oshimura M., Chen D.J., Kurimasa A. 17272272
(RDB 3022) pCMX-N/RBP-J (R218H) Notch Ligand Delta-Like 1 Is Essential for Postnatal Arteriogenesis. Circ. Res., 100, 363-371 (2007). Limbourg A., Ploom M., Elligsen D., Sorensen I., Ziegelhoeffer T., Gossler A., Drexler H., Limbourg F.P. 17234965
(RDB 2925) Nojima cDNA Library Collection No.35. Interactions between peptides containing nucleobase amino acids and T7 phages displaying S. cerevisiae proteins. Biopolymers, 88, 131-140 (2007). Watanabe S., Tomizaki K.Y., Takahashi T., Usui K., Kajikawa K., Mihara H. 17206624


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2006年

RDB No. Title Journal Author PMID
(RDB 1184) Mouse E-cadherin full length cDNA E-cadherin-coated plates maintain pluripotent ES cells without colony formation. PLoS One, 1, (2006). Nagaoka M., Koshimizu U., Yuasa S., Hattori F., Chen H., Tanaka T., Okabe M., Fukuda K., Akaike T. 17183641
(RDB 3022) pCMX-N/RBP-J (R218H)
(RDB 3023) pCMX-N/VP16-RBP-J
(RDB 1801) RBP-J
Canonical notch signaling functions as a commitment switch in the epidermal lineage. Gene. Dev., 20, 3022-3035 (2006). Blanpain C., Lowry W.E., Pasolli H.A., Fuchs E. 17079689
(RDB 1524) pCAhMCSF Retrovirus-mediated conditional immortalization and analysis of established cell lines of osteoclast precursor cells. Biochem. Biophys. Res. Commun., 350, 97-104 (2006). Kawata S., Suzuki J., Maruoka M., Mizutamari M., Ishida-Kitagawa N., Yogo K., Jat P.S., Shishido T. 17005159
(RDB 1748) AxCANCre Assessment of in vitro applicability of reversibly immortalized NKNT-3 cells and clonal derivatives. Cell Transplant., 15, 423-433 (2006). Hoekstra R., Deurholt T., ten Bloemendaal L., Desille M., van Wijk A.C., Clement B., Oude Elferink R.P., van Gulik T.M., Chamuleaut R.A. 16970284
(RDB 4215) CEPH MEGA YAC Clone() Mutation analyses of genes on 6p12-p11 in patients with juvenile myoclonic epilepsy. Neurosci. Lett., 405, 126-131 (2006). Suzuki T., Delgado-Escueta A.V., Alonso M.E., Morita R., Okamura N., Sugimoto Y., Bai D., Medina M.T., Bailey JN, Rasmussen A, Ramos-Peek J, Cordova S, Rubio-Donnadieu F, Ochoa A., Jara-Prado A., Inazawa J., Yamakawa K. 16876319
(RDB 1745) AxCALacZ
(RDB 2012) AxCAhPTEN1
Suppression of PTEN expression during aggregation with retinoic acid in P19 mouse embryonal carcinoma cells. Biochem. Biophys. Res. Commun., 347, 715-722 (2006). Lee J.H., Shin S.Y., Kim S., Choo J., Lee Y.H. 16842746
(RDB 1678) pAxCAwt Overexpression of SOCS3 inhibits astrogliogenesis and promotes maintenance of neural stem cells J. Neurochem., 98, 459?470 (2006). Fang Cao, Ryuji Hata, Pengxiang Zhu, Yong-Jie Ma, Junya Tanaka, Yasushi Hanakawa, Koji Hashimoto, Michio Niinobe, Kazuaki Yoshikawa, Masahiro Sakanaka 16805839
(RDB 1746) Ax1w1 Direct modulation of rheumatoid inflammatory mediator expression in retinoblastoma protein-dependent and -independent pathways by cyclin-dependent kinase 4/6. Arthritis Rheum., 54, 2074-2083 (2006). Nonomura Y., Nagasaka K., Hagiyama H., Sekine C., Nanki T., Tamamori-Adachi M., Miyasaka N., Kohsaka H. 16802342
(RDB 1748) AxCANCre The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development. Development, 133, 3005-3013 (2006). Sakaki-Yumoto M., Kobayashi C., Sato A., Fujimura S., Matsumoto Y., Takasato M., Kodama T., Aburatani H., Asashima M., Yoshida N., Nishinakamura R. 16790473
(RDB 1674) pCALNLw Ductal origin of pancreatic adenocarcinomas induced by conditional activation of a human Ha-ras oncogene in rat pancreas. Carcinogenesis, 27, 2497-2510 (2006). Ueda S., Fukamachi K., Matsuoka Y., Takasuka N., Takeshita F., Naito A., Iigo M., Alexander D.B., Moore M.A., Saito I., Ochiya T., Tsuda H. 16774944
(RDB 2354) pEF-Flag-mSTATY705F Mouse model of human infertility: transient and local inhibition of endometrial STAT-3 activation results in implantation failure. FEBS Lett., 580, 2717-2722 (2006). Nakamura H., Kimura T., Koyama S., Ogita K., Tsutsui T., Shimoya K., Taniguchi T., Koyama M., Kaneda Y., Murata Y. 16647058
(RDB 1679) pCALwL Transgenic mouse for conditional, tissue-specific Cox-2 overexpression Genesis, 44, 177-182 (2006). Ken-ichiro Kamei, Tomo-o Ishikawa, Harvey R. Herschman 16604526
(RDB 1524) pCAhMCSF Src homology 2 (SH2)-containing 5′-inositol phosphatase localizes to podosomes, and the SH2 domain is implicated in the attenuation of bone resorption in osteoclasts. Endocrinology, 147, 3307-3317 (2006). Yogo K., Mizutamari M., Mishima K., Takenouchi H., Ishida-Kitagawa N., Sasaki T., Takeya T. 16601135
(RDB 1679) pCALwL Targeted gene therapy toward astrocytoma using a Cre/loxP-based adenovirus system. Brain Res., 1081, 34-43 (2006). Maeda M., Namikawa K., Kobayashi I., Ohba N., Takahara Y., Kadono C., Tanaka A,, Kiyama H. 16529724
(RDB 1417) AxCAmIL12p40
(RDB 1414) AxCAmIL12p35
The boosting effect of co-transduction with cytokine genes on cancer vaccine therapy using genetically modified dendritic cells expressing tumor-associated antigen. Int. J. Oncol., 28, 947-953 (2006). Ojima T., Iwahashi M., Nakamura M., Matsuda K., Naka T., Nakamori M., Ueda K., Ishida K., Yamaue H. 16525645
(RDB 4755) pcDNA4-mmJDP2_wt
(RDB 4757) pGST-mmJDP2_full
Regulation of histone acetylation and nucleosome assembly by transcription factor JDP2. Nat. Struct. Mol. Biol., 13, 331-338 (2006). Jin C., Kato K., Chimura T., Yamasaki T., Nakade K., Murata T., Li H., Pan J., Zhao M., Sun K., Chiu R., Ito T., Nagata K., Horikoshi M., Yokoyama K.K. 16518400
(RDB 2012) AxCAhPTEN1 Suppression of Egr-1 transcription through targeting of the serum response factor by oncogenic H-Ras. EMBO J., 25, 1093-1103 (2006). Shin S.Y., Bahk Y.Y., Ko J., Chung I.Y., Lee Y.S., Downward J., Eibel H., Sharma P.M., Olefsky J.M., Kim Y.H., Lee B., Lee Y.H. 16456537
(RDB 1208) pRHO1 Lipopolysaccharide-induced microglial activation induces learning and memory deficits without neuronal cell death in rats. J. Neurosci. Res., 83, 557-566 (2006). Tanaka S., Ide M., Shibutani T., Ohtaki H., Numazawa S., Shioda S., Yoshida T. 16429444
(RDB 1960) pGMT20 A Novel Yeast-Based Reporter Assay System for the Sensitive Detection of Genotoxic Agents Mediated by a DNA Damage-Inducible LexA-GAL4 Protein. J. Biochem. (Tokyo)., 139, 105-112 (2006). Ichikawa K., Eki T. 16428325
(RDB 1184) Mouse E-cadherin full length cDNA Cutting edge: identification of E-cadherin as a ligand for the murine killer cell lectin-like receptor G1. J. Immunol., 176, 1311-1315 (2006). Grundemann C., Bauer M., Schweier O., von Oppen N., Lassing U., Saudan P., Becker K.F., Karp K., Hanke T., Bachmann M.F., Pircher H. 16424155
(RDB 2410) AxCALNLrmaf2 (forward)
(RDB 1748) AxCANCre
Activation of connective tissue growth factor gene by the c-Maf and Lc-Maf transcription factors. Biochem. Biophys. Res. Commun., 339, 1089-1097 (2006). Omoteyama K., Ikeda H., Imaki J., Sakai M. 16343439
(RDB 2355) pEF-NFIL6 CCAAT/enhancer binding protein beta binds to and activates the P670 promoter of human papillomavirus type 16. Virology, 346, 98-107 (2006). Kukimoto I., Takeuchi T., Kanda T. 16307770
(RDB 2755) AxCAhp53WT (forward) Defect in serine 46 phosphorylation of p53 contributes to acquisition of p53 resistance in oral squamous cell carcinoma cells. Oncogene, 25, 1216-1224 (2006). Ichwan S.J., Yamada S., Sumrejkanchanakij P., Ibrahim-Auerkari E., Eto K., Ikeda M.A. 16247456
(RDB 1745) AxCALacZ CTLA-4Ig suppresses liver injury by inhibiting acquired immune responses in a mouse model of fulminant hepatitis. Hepatology, 42, 915-924 (2006). Nakayama Y., Shimizu Y., Hirano K., Ebata K., Minemura M., Watanabe A., Sugiyama T. 16175605
(RDB 1466) pMFG SV40tsT Relationship between the P53 functional status of human tumor cell lines and their chemosensitivities to different anticancer drug. Chin. Edu. Gen. Pract., 4 (2006). TAN Yajun,LOU Bin,CHEN Yu.


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2005年

RDB No. Title Journal Author PMID
(RDB 1687) pCM-hGM
(RDB 1685) pCM-hIL4
Identification of HIV-1 epitopes that induce the synthesis of a R5 HIV-1 suppression factor by human CD4+ T cells isolated from HIV-1 immunized hu-PBL SCID mice. Clin. Dev. Immunol., 12, 235-242 (2005). Yoshida A., Tanaka R., Kodama A., Yamamoto N., Ansari A.A., Tanaka Y. 16584108
(RDB 2355) pEF-NFIL6 The role of pit-1 in the regulation of the rat growth hormone-releasing hormone receptor gene transcription by glucocorticoids. J. Mol. Endocrinol., 35, 477-488 (2005). Nogami H., Hiraoka Y., Ogasawara K., Aiso S., Hisano S. 16326834
(RDB 2443) pCAcc-Luc+ Light-induced gene transfer from packaged DNA enveloped in a dendrimeric photosensitizer. Nat. Mater., 4, 934-941 (2005). Nishiyama N., Iriyama A., Jang W.D., Miyata K., Itaka K., Inoue Y., Takahashi H., Yanagi Y., Tamaki Y., Koyama H., Kataoka K. 16299510
(RDB 1864) cDNA library of mixed-stage C. elegans for yeast two-hybrid screening Homologues of the Caenorhabditis elegans Fox-1 protein are neuronal splicing regulators in mammals. Mol. Cell. Biol., 25 (22), 10005-10016 (2005). Underwood, J.G., Boutz, P.L., Dougherty, J.D., Stoilov, P., Black, D.L. 16260614
(RDB 1678) pAxCAwt Downregulation of cyclin-dependent kinase inhibitor; p57(kip2), is involved in the cell cycle progression of vascular smooth muscle cell. Biochem. Biophys. Res. Commun., 338, 1661-1667 (2005). Nakano, N., Urasawa, K., Takagi, Y., Saito, T., Kaneta, S., Ishikawa, S., Higashi, H., Tsutsui, H., Hatakeyama, M., Kitabatake, A. 16259944
(RDB 2164) Ad5-F/asMSH alpha
(RDB 2166) Ad5-F/asMSH beta
(RDB 2169) Ad5-F/gsMSH beta
(RDB 2171) Ad5-F/asK21MSH alpha
(RDB 2167) Ad5-F/gsMSH alpha
(RDB 2193) Ad5-F/RGD
(RDB 2209) Ad5-F/asK21MSH beta
(RDB 2225) Ad5-F/asSS14
(RDB 2227) Ad5-F/asSS28
(RDB 2232) Ad5-F/asGRP27
(RDB 2235) Ad5-F/asSec
(RDB 2257) Ad5-F/540S
(RDB 4245) Ad5-F/K20
(RDB 2241) AxCAhp53-F/wt
(RDB 2014) AxCAhIL2-F/K20
(RDB 2229) AxCAZ2-F/asSS28
(RDB 2233) AxCAZ3-F/asGRP27
(RDB 2255) AxdAdB3-F/K20 Clal(+)
(RDB 2033) AxCAhp53-F/K20
(RDB 2219) AxCIhIL12-F/K20
(RDB 1747) Ad5-dlX
Accumulation of infectious mutants in stocks during the propagation of fiber-modified recombinant adenoviruses. Biochem. Biophys. Res. Commun. 337, 806-814 (2005). Ugai H., Inabe K., Yamasaki T., Murata T., Obata Y., Hamada H., Yokoyama K.K. 16214112
(RDB 1748) AxCANCre
(RDB 2004) AxCALNLBcl2a
Mitochondrial impairment induced by poly(ADP-ribose) polymerase-1 activation in cortical neurons after oxygen and glucose deprivation. J. Neurochem., 95, 179-190 (2005). Tanaka S., Takehashi M., Iida S., Kitajima T., Kamanaka Y., Stedeford T., Banasik M., Ueda K. 16181422
(RDB 1418) pAxCAmGM-CSF Overexpression of granulocyte-macrophage colony-stimulating factor in mouse liver enhances the susceptibility of lipopolysaccharide leading to massive apoptosis of hepatocytes Liver Int., 25, 1027-1035 (2005). Hirano, K., Shimizu, Y., Nakayama, Y., Minemura, M., Yasumura, S., Sugiyama, T. 16162163
(RDB 1748) AxCANCre Ribozymes targeting serine/threonine kinase Akt1 sensitize cells to anticancer drugs. Cancer Sci., 96, 620-6 (2005). Yanagihara M., Katano M., Takahashi-Sasaki N., Kimata K., Taira K., Andoh T. 16128748
(RDB 1476) pBluescript SKII+mIL10 Adenovirus-mediated gene delivery of interleukin-10, but not transforming growth factor beta, ameliorates the induction of Graves’ hyperthyroidism in BALB/c mice. Clin. Exp. Immunol., 141, 405-411 (2005). Saitoh O., Mizutori Y., Takamura N., Yamasaki H., Kita A., Kuwahara H., Nagayama Y. 16045729
(RDB 1746) Ax1w1 Adenovirus-mediated expression of heparin cofactor II inhibits thrombin-induced cellular responses in fibroblasts and vascular smooth muscle cells. Thromb. Res., 116, 357-363 (2005). Hayakawa Y., Hirashima Y., Yamamoto H., Hayashi N., Kurimoto M., Kuwayama N., Endo S. 16038721
(RDB 1524) pCAhMCSF Physical and functional association of c-Src and adhesion and degranulation promoting adaptor protein (ADAP) in osteoclastogenesis in vitro. J. Biol. Chem., 280, 31564-31571 (2005). Koga S., Yogo K., Yoshikawa K., Samori H., Goto M., Uchida T., Ishida N., Takeya T. 16020549
(RDB 2241) AxCAhp53-F/wt
(RDB 1745) AxCALacZ
Adenovirus-mediated p53 gene transfer to the bile duct by direct administration into the bile in a rat cholangitis model. J. Surg. Res., 128, 126-131 (2005). Kojima Y., Honda K., Kotegawa H., Kushihata F., Kobayashi N., Liu B., Yokoyama K.K. 16005898
(RDB 1204) WEE1Hu Akt/protein kinase B-dependent phosphorylation and inactivation of WEE1Hu promote cell cycle progression at G2/M transition. Mol. Cell. Biol., 25, 5725-5737 (2005). Katayama K., Fujita N., Tsuruo T. 15964826
(RDB 1245) P450 2B1 (CYP2B1) cDNA Impaired nuclear translocation of CAR in hepatic preneoplastic lesions: association with an attenuated CYP2B induction by phenobarbital. FEBS Lett., 579, 3560-3564 (2005). Numazawa S., Shindo S., Maruyama K., Chibana F., Kawahara Y., Ashino T., Tanaka S., Yoshida T. 15953603
(RDB 1678) pAxCAwt Suppression of Stat3 promotes neurogenesis in cultured neural stem cells. J. Neurosci. Res., 81, 163-171 (2005). Gu F., Hata R., Ma Y.J., Tanaka J., Mitsuda N., Kumon Y., Hanakawa Y., Hashimoto K., Nakajima K., Sakanaka M. 15948155
anonymous A database of recombinant viruses and recombinant viral vectors available from the RIKEN DNA bank. J. Gene Med., 7, 1148-1157 (2005). Ugai H., Murata T., Nagamura Y., Ugawa Y., Suzuki E., Nakata H., Kujime Y., Inamoto S., Hirose M., Inabe K., Terashima M., Yamasaki T., Liu B., Nakade K., Pan J., Kimura M., Saito I., Hamada H., Obata Y., Yokoyama K.K. 15945121
(RDB 3432) pBlue hNF-IL6 (610 Sal I) C/EBPalpha functionally and physically interacts with GABP to activate the human myeloid IgA Fc receptor (Fc alphaR, CD89) gene promoter. Blood, 106, 2534-2542 (2005). Shimokawa T., Ra C. 15928042
(RDB 3121) pAxCAwtit Secretory phospholipases A2 induce neurite outgrowth in PC12 cells through lysophosphatidylcholine generation and activation of G2A receptor. J. Biol. Chem., 280, 28044-28052, (2005). Ikeno Y., Konno N., Cheon S.H., Bolchi A., Ottonello S., Kitamoto K., Arioka M. 15927955
(RDB 1516) pCAmsIL1 alpha Interference with the IL-1-signaling pathway improves the toxicity profile of systemically applied adenovirus vectors. J. Immunol., 174, 7310-7319 (2005). Shayakhmetov D.M., Li Z.Y., Ni S., Lieber A. 15905578
(RDB 1870) pCAZ 2
(RDB 1681) pCMV (Hu beta)
Gene therapy for hepatocellular carcinoma using sonoporation enhanced by contrast agents Cancer Gene Ther., 12, 884-889 (2005). Sakakima Y., Hayashi S., Yagi Y., Hayakawa A., Tachibana K., Nakao A. 15891773
(RDB 1578) AxCEAprTK An efficient construction of conditionally replicating adenoviruses that target tumor cells with multiple factors. Gene. Ther., 12, 1385-1393 (2005). Nagano S., Oshika H., Fujiwara H., Komiya S., Kosai K. 15877049
(RDB 1745) AxCALacZ Galpha12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts. J. Biol. Chem., 280, 23041-23047 (2005). Fujii T., Onohara N., Maruyama Y., Tanabe S., Kobayashi H., Fukutomi M., Nagamatsu Y., Nishihara N., Inoue R., Sumimoto H., Shibasaki F., Nagao T., Nishida M., Kurose H. 15826947
(RDB 6792) H3001F04
(RDB 6795) H3007A09
(RDB 6796) H3010A01
(RDB 6798) H3015C08
(RDB 6799) H3015F09
(RDB 6800) H3016D10
(RDB 6803) H3023C07
(RDB 6804) H3023C08
(RDB 6805) H3024A07
(RDB 6806) H3026A08
(RDB 6810) H3029F03
(RDB 6811) H3031C12
(RDB 6812) H3031E01
(RDB 6814) H3034B07
(RDB 6816) H3038B03
(RDB 6821) H3050F06
(RDB 6822) H3051B02
(RDB 6823) H3053A12
(RDB 6824) H3054C02
(RDB 6825) H3059B11
(RDB 6827) H3059G11
(RDB 6828) H3065A10
(RDB 6829) H3065B05
(RDB 6830) H3066H08
(RDB 6831) H3069B09
(RDB 6832) H3072G10
(RDB 6834) H3079F11
(RDB 6835) H3079H10
(RDB 6836) H3080H11
(RDB 6837) H3082B04
(RDB 6838) H3084G03
(RDB 6839) H3085D08
(RDB 6840) H3085D10
(RDB 6841) H3096A11
(RDB 6842) H3098E12
(RDB 6843) H3099C01
(RDB 6844) H3100C12
(RDB 6845) H3101A12
(RDB 6846) H3106B04
(RDB 6847) H3106E01
(RDB 6848) H3108A04
(RDB 6849) H3108A08
(RDB 6850) H3110E08
(RDB 6851) H3113D09
(RDB 6852) H3114H08
(RDB 6853) H3118C05
(RDB 6854) H3120D11
(RDB 6855) H3125H07
(RDB 6856) H3126B12
(RDB 6857) H3129D07
(RDB 6858) H3129E11
(RDB 6859) H3131B07
(RDB 6863) H3140A03
(RDB 6864) H3143B05
(RDB 6865) H3145H12
(RDB 6866) H3146C03
(RDB 6868) H3147A08
(RDB 6869) H3154B06
(RDB 6870) H3156A09
(RDB 6871) H3156B03
(RDB 6872) H3157D08
(RDB 6861) H3138G12
Immediate early genes of glucocorticoid action on the developing intestine. Am. J. Physiol. Gastrointest. Liver Physiol. 288, G897-G906, 2005 Agbemafle B.M., Oesterreicher T.J., Shaw C.A., Henning S.J. 15826934
anonymous Recombinant Virus Bank for gene delivery. Science, 307, 1722 (2005). Yokoyama K.K., Murata T, Ugai H., Suzuki E., Terashima M., Kujime Y., Inamoto S., Hirose M., Inabe K., Yamasaki T. 15774743
(RDB 1126) pSVtsA58 ori (-) Functional characterization of a conditionally immortalized mouse epididymis caput epithelial cell line MEPC5 using temperature-sensitive simian virus 40 large T-antigen. Biochem. Biophys. Res. Commun., 329, 812-823 (2005). Tabuchi Y, Toyama Y, Toshimori K, Komiyama M, Mori C, Kondo T. 15752729
(RDB 1745) AxCALacZ G alpha 12/13- and reactive oxygen species-dependent activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase by angiotensin receptor stimulation in rat neonatal cardiomyocytes. J. Biol. Chem., 280, 18434-18441 (2005). Nishida M., Tanabe S., Maruyama Y., Mangmool S., Urayama K., Nagamatsu Y., Takagahara S., Turner J.H., Kozasa T., Kobayashi H., Sato Y., Kawanishi T., Inoue R., Nagao T., Kurose H. 15743761
(RDB 2048) AxE1AdB
(RDB 1743) Ax1 CAUP
(RDB 2031) AxE1CAUP
(RDB 2032) pAxE1CAUP
(RDB 1745) AxCALacZ
Effective gene therapy of biliary tract cancers by a conditionally replicative adenovirus expressing uracil phosphoribosyltransferase: significance of timing of 5-fluorouracil administration. Cancer Res., 65, 546-552 (2005). Seo E., Abei M., Wakayama M., Fukuda K., Ugai H., Murata T., Todoroki T., Matsuzaki Y., Tanaka N., Hamada H., Yokoyama K.K. 15695398
(RDB 5722) NIA/NIH Mouse cDNA() Gene expression profiling of cathepsin D, metallothioneins-1 and -2, osteopontin, and tenascin-C in a mouse spinal cord injury model by cDNA microarray analysis. Acta Neuropathol., 109, 165-180 (2005). Hashimoto M., Koda M., Ino H., Yoshinaga K., Murata A., Yamazaki M., Kojima K., Chiba K., Mori C., Moriya H. 15592854
(RDB 1750) AxCALNLNZ
(RDB 1748) AxCANCre
Delection of the PDGFR-beta Gene Affects Key Fibroblast Functions Important for Wound Healing J. Biol. Chem., 280, 9375-9389 (2005). Gao Z., Sasaoka T., Fujimori T., Oya T., Ishii Y., Sabit H., Kawaguchi M., Kurotaki Y., Naito M., Wada T., Ishizawa S., Kobayashi M., Nabeshima Y., Sasahara M. 15590688
(RDB 3021) pCMX-N/RBP-J Distinct roles of EGF repeats for the Notch signaling system. Exp. Cell Res., 302, 281-291 (2005). Sakamoto K., Chao W.S., Katsube K., Yamaguchi A. 15561108


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2004年

RDB No. Title Journal Author PMID
(RDB 1276) pco12 EGFR Production of soluble mammalian proteins in Escherichia coli: identification of protein features that correlate with successful expression BMC Biotechnol., 4, 1-18 (2004). Dyson M.R., Shadbolt S.P., Vincent K.J., Perera R.L., McCafferty J. 15598350
(RDB 1210) CDMmMCSFCl7 Induction of mouse c-src in RAW264 cells is dependent on AP-1 and NF-kappaB and important for progression to multinucleated cell formation. Biochem. Biophys. Res. Commun., 325, 758-768 (2004). Kumagai N., Ohno K., Tameshige R., Hoshijima M., Yogo K., Ishida N., Takeya T. 15541355
(RDB 1675) pxCANCre An antigen-mediated selection system for mammalian cells that produce glycosylated single-chain Fv. Biochem. Biophys. Res. Commun., 324, 1165-1172 (2004). Pihkala P., Kawahara M., Ueda H., Nagamune T. 15504336
(RDB 1748) AxCANCre Angiogenic endothelium-specific nestin expression is enhanced by the first intron of the nestin gene. Lab. Invest., 84, 1581-1592 (2004). Aihara M., Sugawara K., Torii S., Hosaka M., Kurihara H., Saito N., Takeuchi T. 15502861
(RDB 1476) pBluescript SKII+mIL10 Adeno-associated virus vector-mediated interleukin-10 gene transfer inhibits atherosclerosis in apolipoprotein E-deficient mice. Gene Ther., 11, 1772-1779 (2004). Yoshioka T., Okada T., Maeda Y., Ikeda U., Shimpo M., Nomoto T., Takeuchi K., Nonaka-Sarukawa M., Ito T., Takahashi M., Matsushita T., Mizukami H., Hanazono Y., Kume A., Ookawara S., Kawano M., Ishibashi S., Shimada K., Ozawa K. 15496963
(RDB 1748) AxCANCre Cardiomyocytes fuse with surrounding noncardiomyocytes and reenter the cell cycle. J. Cell Biol., 167, 351-363 (2004). Matsuura K., Wada H., Nagai T., Iijima Y., Minamino T., Sano M., Akazawa H., Molkentin J.D., Kasanuki H., Komuro I. 15492039
(RDB 1745) AxCALacZ Functional activity of human hepatoma cells transfected with adenovirus-mediated hepatocyte nuclear factor (HNF)-4 gene. Cell Transplant., 13, 393-403 (2004). Naiki T., Nagaki M., Shidoji Y., Kojima H., Moriwaki H. 15468681
(RDB 1376) pUC-ER6 Effects of the phytoestrogen coumestrol on RANK-ligand-induced differentiation of osteoclasts. Toxicology., 203, 211-220 (2004). Kanno S., Hirano S., Kayama F. 15363596
(RDB 1484) pBluescript SKII+mLIF Alteration of the timing of implantation by in vivo gene transfer: delay of implantation by suppression of nuclear factor kappaB activity and partial rescue by leukemia inhibitory factor. Biochem. Biophys. Res. Commun., 321, 886-892 (2004). Nakamura H., Kimura T., Ogita K., Koyama S., Tsujie T., Tsutsui T., Shimoya K., Koyama M., Kaneda Y., Murata Y. 15358109
(RDB 1130) pBS rcjun-1 Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation. J. Clin. Invest., 114, 475-484 (2004). Ikeda F., Nishimura R., Matsubara T., Tanaka S., Inoue J., Reddy S.V., Hata K., Yamashita K., Hiraga T., Watanabe T., Kukita T., Yoshioka K., Rao A., Yoneda T. 15314684
(RDB 1775) Six4 (M18 type)
(RDB 1776) Six4 (SM type)
(RDB 1774) Six4 (M8 type)
Reciprocal signaling between the transcriptional co-factor Eya2 and specific members of the Galphai family. Mol. Pharmacol., 66, 1325-1331 (2004). Embry A.C., Glick J.L., Linder M.E., Casey P.J. 15308761
anonymous Genes for systemic vascular complications are differentially expressed in the livers of type 2 diabetic patients. Diabetologia, 47, 638-647 (2004). Takamura T., Sakurai M., Ota T., Ando H., Honda M., Kaneko S. 15298340
(RDB 1745) AxCALacZ Development of donor-specific immunoregulatory T-cells after local CTLA4Ig gene transfer to pancreatic allograft. Transplantation, 78, 59-64 (2004). Miao G., Ito T., Uchikoshi F., Akamaru Y., Kiyomoto T., Komodo H., Song J., Nozawa M., Matsuda H. 15257039
(RDB 1747) Ad5-dlX Cell specificity and efficiency of the Semliki forest virus vector- and adenovirus vector-mediated gene expression in mouse cerebellum. J. Neurosci. Methods, 137, 111-121 (2004). Sato Y., Shiraishi Y., Furuichi T. 15196833
(RDB 1476) pBluescript SKII+mIL10 A method for oral DNA delivery with N-acetylated chitosan. Pharm. Res., 21, 838-843 (2004). Kai E., Ochiya T. 15180343
(RDB 1402) AxCAmIL2 Dendritic cell vaccine therapy by immunization with fusion cells of interleukin-2 gene-transduced, spleen-derived dendritic cells and tumour cells. Scand. J. Immunol., 59, 432-439 (2004). Ogawa F., Iinuma H., Okinaga K. 15140052
(RDB 1748) AxCANCre Separate control of Rep and Cap expression using mutant and wild-type loxP sequences and improved packaging system for adeno-associated virus vector production. Mol. Biotechnol., 27, 7-14 (2004). Mizukami H., Okada T., Ogasawara Y., Matsushita T., Urabe M., Kume A., Ozawa K. 15122043
(RDB 1745) AxCALacZ
(RDB 1998) AxCAhp21
Induction of CDK inhibitor p21 gene as a new therapeutic strategy against pulmonary fibrosis. Am. J. Physiol. Lung Cell. Mol. Physiol., 286, L727-L733 (2004). Inoshima I., Kuwano K., Hamada N., Yoshimi M., Maeyama T., Hagimoto N., Nakanishi Y., Hara N. 15003936
(RDB 1402) AxCAmIL2 Gene therapy eradicating distant disseminated micro-metastases by optimal cytokine expression in the primary lesion only: novel concepts for successful cytokine gene therapy. Int. J. Oncol., 24, 549-558 (2004). Nagano S., Yuge K., Fukunaga M., Terazaki Y., Fujiwara H., Komiya S., Kosai K. 14767539
(RDB 1829) Bombyx POU-M1/SGF-3 Identification of a POU factor involved in regulating the neuron-specific expression of the gene encoding diapause hormone and pheromone biosynthesis-activating neuropeptide in Bombyx mori. Biochem. J., 380, 255-263 (2004). Zhang T.Y., Kang L., Zhang Z.F., Xu W.H. 14766018
(RDB 1888) pRx-mGMCSF-bsr Immature dendritic cells reduce proinflammatory cytokine production by a coculture of macrophages and apoptotic cells in a cell-to-cell contact-dependent manner. J. Leukoc. Biol., 75, 865-873 (2004). Takahashi M., Kurosaka K., Kobayashi Y. 14761936
(RDB 1892) pSK II+[X-K]nbK20 Model of unidirectional transluminal gene transfer. Mol. Ther., 9, 305-310 (2004). Arap MA, Lahdenranta J, Hajitou A, Marini FC 3rd, Wood CG, Wright KC, Fueyo J, Arap W, Pasqualini R. 14759814
(RDB 1205) pHT gamma 1 Quercetin enhances melanogenesis by increasing the activity and synthesis of tyrosinase in human melanoma cells and in normal human melanocytes. Pigment Cell Res. 17, 66-73 (2004). Nagata, H., Takekoshi, S., Takeyama, R., Homma, T., Osamura, R.Y. 14717847
(RDB 1890) pRx-crmA-bsr Xenopus death receptor-M1 and -M2, new members of the tumor necrosis factor receptor superfamily, trigger apoptotic signaling by differential mechanisms. J. Biol. Chem., 279, 7629-7635 (2004) Tamura K., Noyama T., Ishizawa YH., Takamatsu N., Shiba T., Ito M. 14668340
(RDB 1749) AxCANLacZ A simple method for the simultaneous detection of E1A and E1B in adenovirus stocks. Oncol. Rep., 11, 173-178 (2004). Suzuki E., Murata T., Watanabe S., Kujime Y., Hirose M., Pan J., Yamazaki T., Ugai H., Yokoyama K.K. 14654922
(RDB 1127) pHSP90 S100A1 is a novel molecular chaperone and a member of the Hsp70/Hsp90 multichaperone complex. J. Biol. Chem., 279, 4221-4233 (2004). Okada M., Hatakeyama T., Itoh H., Tokuta N., Tokumitsu H., Kobayashi R. 14638689
(RDB 1748) AxCANCre Stress induces mitochondria-mediated apoptosis independent of SAPK/JNK activation in embryonic stem cells. J. Biol. Chem., 279, 1621-1626 (2004). Nishitai G., Shimizu N., Negishi T., Kishimoto H., Nakagawa K., Kitagawa D., Watanabe T., Momose H., Ohata S., Tanemura S., Asaka S., Kubota J., Saito R., Yoshida H., Mak T.W., Wada T., Penninger J.M., Azuma N., Nishina H., Katada T. 14585831
(RDB 2241) AxCAhp53-F/wt
(RDB 1745) AxCALacZ
Adenovirus-mediated p53 gene transfer to the biliary tract in a rat cholangitis model. J. Japan Biliary Assoc., 18, 174-181 (2004). Kojima Y., Honda K., Yokoyama K.K, Kushihata F., Kobayashi N.


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2003年

RDB No. Title Journal Author PMID
(RDB 1463) pMFG rat GM-CSF Thyroid cancer immuno-therapy with retroviral and adenoviral vectors expressing granulocyte macrophage colony stimulating factor and interleukin-12 in a rat model. Clin. Endocrinol., 59, 734-742 (2003). Tanaka K., Towata S., Nakao K., Mizuguchi H., Hayakawa T., Niwa M., Ishii N., Nagayama Y. 14974915
(RDB 1622) Human PAF receptor Effects of rhinovirus infection on the adherence of Streptococcus pneumoniae to cultured human rirway epithelial cells. J. Infect. Dis., 188, 1928-1939 (2003). Ishizuka S., Yamaya M., Suzuki T., Takahashi H., Ida S., Sasaki T., Inoue D., Sekizawa K., Nishimura H., Sasaki H. 14673774
(RDB 5953) pCM-TK Inducible liver injury in the transgenic rat by expressing liver-specific suicide gene. Biochem. Biophys. Res. Commun., 311, 920-928 (2003). Kawasaki M., Fujino M., Li X.K., Kitazawa Y., Funeshima N., Takahashi R., Ueda M., Amano T., Hakamata Y., Kobayashi E. 14623269
(RDB 1130) pBS rcjun-1 Inhibition by dexamethasone of interleukin 13 production via glucocorticoid receptor-mediated inhibition of c-Jun phosphorylation. FEBS Lett., 554, 489-493 (2003). Hirasawa N., Izumi S., Linwong W., Ohuchi K. 14623117
(RDB 1746) Ax1w1 Gene transfer of a cell cycle modulator exerts anti-inflammatory effects in the treatment of arthritis. J. Immunol., 171, 4913-4919 (2003). Nonomura Y., Kohsaka H., Nagasaka K., Miyasaka N. 14568973
(RDB 1864) cDNA library of mixed-stage C. elegans for yeast two-hybrid screening Involvement of fatty acid pathways and cortical interaction of the pronuclear complex in Caenorhabditis elegans embryonic polarity. BMC Dev. Biol., 3, 8 (2003). Nonomura Y., Kohsaka H., Nagasaka K., Miyasaka N. 14527340
(RDB 1126) pSVtsA58 ori (-) Roles of MGMT and MLH1 proteins in alkylation-induced apoptosis and mutagenesis. DNA Repair (Amst)., 2, 1135-1146 (2003). Takagi Y., Takahashi M., Sanada M., Ito R., Yamaizumi M., Sekiguchi M. 13679151
(RDB 1748) AxCANCre Immortalization of bone marrow-derived human mesenchymal stem cells by removable simian virus 40T antigen gene: analysis of the ability to support expansion of cord blood hematopoietic progenitor cells. Int. J. Oncol., 23, 925-32 (2003). Nishioka K., Fujimori Y., Hashimoto-Tamaoki T., Kai S., Qiu H., Kobayashi N., Tanaka N., Westerman K.A, Leboulch P., Hara H. 12963970
(RDB 1746) Ax1w1 E1A, E1B double-restricted adenovirus for oncolytic gene therapy of gallbladder cancer. Cancer Res., 63, 4434-4440 (2003). Fukuda K., Abei M., Ugai H., Seo E., Wakayama M., Murata T., Todoroki T., Tanaka N., Hamada H., Yokoyama K.K. 12907616
(RDB 1687) pCM-hGM
(RDB 1685) pCM-hIL4
Induction of protective immune responses against R5 human immunodeficiency virus type 1 (HIV-1) infection in hu-PBL-SCID mice by intrasplenic immunization with HIV-1-pulsed dendritic cells: possible involvement of a novel factor of human CD4(+) T-cell origin. J. Virol., 77, 8719-8728 (2003). Yoshida A., Tanaka R., Murakami T., Takahashi Y., Koyanagi Y., Nakamura M., Ito M., Yamamoto N., Tanaka Y. 12885891
(RDB 1739) Ax1 CI hp40ip35 Adenoviral interleukin-12 gene transduction into human bronchial epithelial cells: up-regulation of pro-inflammatory cytokines and its prevention by corticosteroids. Clin. Exp. Allergy., 33, 921-929 (2003). Ogawa H., Nishimura N., Nishioka Y., Azuma M., Yanagawa H., Sone S. 12859448
(RDB 1745) AxCALacZ Effect of an adenoviral vector that expresses the canine p53 gene on cell growth of canine osteosarcoma and mammary adenocarcinoma cell lines. Am. J. Vet. Res., 64, 880-888 (2003). Yazawa M., Setoguchi A., Hong S.H., Uyama R., Nakagawa T., Kanaya N., Nishimura R., Sasaki N., Masuda K., Ohno K., Tsujimoto H. 12856773
(RDB 1748) AxCANCre Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation. Biochem. J., 375, 365-371 (2003). Furuyama T., Kitayama K., Yamashita H., Mori N. 12820900
(RDB 1127) pHSP90 Hsp90 is a direct target of the anti-allergic drugs disodium cromoglycate and amlexanox. Biochem. J., 374, 433-441 (2003). Okada M., Itoh H., Hatakeyama T., Tokumitsu H., Kobayashi R. 12803546
(RDB 1372 ) Human MDR1 cDNA Human MDR1 polymorphism: G2677T/A and C3435T have no effect on MDR1 transport activities. Biochem. Pharmacol., 65, 1843-1852 (2003). Morita N., Yasumori T., Nakayama K. 12781336
(RDB 1419) AxCAmGM-CSF Insight into antibody responses induced by plasmid or adenoviral vectors encoding thyroid peroxidase, a major thyroid autoantigen. Clin. Exp. Immunol., 132, 408-415 (2003). Guo J., Pichurin P., Nagayama Y., Rapoport B., McLachlan S.M. 12780686
anonymous
(RDB 917) pAxcw
Potential tumor suppressive pathway involving DUSP6/MKP-3 in pancreatic cancer. Am. J. Pathol., 162, 1807-1815 (2003). Furukawa T., Sunamura M., Motoi F., Matsuno S., Horii A. 12759238
(RDB 1745) AxCALacZ Ex vivo and systemic transfer of adenovirus-mediated CTLA4Ig gene combined with a short course of FK506 therapy prolongs islet graft survival. Transpl. Immunol., 11, 91-100 (2003). Akamaru Y., Ito T., Uchikoshi F., Maeda A., Tori M., Kiyomoto T., Komoda H., Miao G., Matsuda H. 12727480
(RDB 1748) AxCANCre Adenovirus-mediated gene transfer of interferon alpha improves dimethylnitrosamine-induced liver cirrhosis in rat model. Gene Ther., 10, 765-773 (2003). Suzuki K., Aoki K., Ohnami S., Yoshida K., Kazui T., Kato N., Inoue K., Kohara M., Yoshida T. 12704415
(RDB 1679) pCALwL Transgenic expression of a dominant-negative connexin26 causes degeneration of the organ of Corti and non-syndromic deafness. Hum. Mol. Genet., 12, 995-1004 (2003). Kudo T., Kure S., Ikeda K., Xia A.P., Katori Y., Suzuki M., Kojima K., Ichinohe A., Suzuki Y., Aoki Y., Kobayashi T., Matsubara Y. 12700168
(RDB 1745) AxCALacZ Recombinant adenovirus vector bearing antisense macrophage migration inhibitory factor cDNA prevents acute lipopolysaccharide-induced liver failure in mice. Lab. Invest., 83, 561-570 (2003). Iwaki T., Sugimura M., Nishihira J., Matsuura T., Kobayashi T., Kanayama N. 12695559
(RDB 1740) Ax1 CI-hp53 (L) E2FBP1/DRIL1, an AT-Rich Interaction Domain-Family Transcription Factor, Is Regulated by p53. Mol. Cancer Res., 1, 438-444 (2003). Ma K., Araki K., Ichwan S.J., Suganuma T., Tamamori-Adachi M., Ikeda M.A. 12692263
(RDB 1473 ) pBluescript KS+mIL4 Prevention of autoantibody-mediated Graves’-like hyperthyroidism in mice with IL-4, a Th2 cytokine. J. Immunol., 170, 3522-3527 (2003). Nagayama Y., Mizuguchi H., Hayakawa T., Niwa M., McLachlan S.M., Rapoport B. 12646613
(RDB 1745) AxCALacZ Differential Requirement of G{alpha}12, G{alpha}13, G{alpha}q, and G{beta gamma} for Endothelin-1-Induced c-Jun NH2-Terminal Kinase and Extracellular Signal-Regulated Kinase Activation. Mol. Pharmacol., 63, 478-488 (2003). Arai K., Maruyama Y., Nishida M., Tanabe S., Takagahara S., Kozasa T., Mori Y., Nagao T., Kurose H. 12606754
(RDB 1257) p40 BamH I-A Reduction of Natural Adenovirus Tropism to the Liver by both Ablation of Fiber-Coxsackievirus and Adenovirus Receptor Interaction and Use of Replaceable Short Fiber. J. Virol., 77, 2512-2521 (2003). Nakamura T., Sato K., Hamada H. 12551989
(RDB 1678) pAxCAwt
(RDB 2547) AxCAHSVtk
Spontaneous mutations in the human gene for p53 in recombinant adenovirus during multiple passages in human embryonic kidney 293 cells. Biochem. Biophys. Res. Commun., 300, 448-456. (2003). Ugai H., Suzuki E., Inabe K., Murata T., Hamada H., Yokoyama K.K. 12504105
(RDB 1579) AxCEAprZ
(RDB 1578) AxCEAprTK
(RDB 2547) AxCAHSVtk
An optimal therapeutic expression level is crucial for suicide gene therapy for hepatic metastatic cancer in mice. Hepatology, 37, 155-163 (2003). Terazaki Y., Yano S., Yuge K., Nagano S., Fukunaga M., Guo Z.S., Komiya S., Shirouzu K., Kosai K. 12500200
(RDB 2075) mST3GalV Region-specific and epileptogenic-dependent expression of six subtypes of alpha2,3-sialyltransferase in the adult mouse brain. J. Neurochem., 84, 53-66 (2003). Matsuhashi H., Horii Y., Kato K. 12485401


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2002年

RDB No. Title Journal Author PMID
(RDB 1393) pGPi2 Method for identification of mutant glutathione S-transferases conferring enhanced resistance to the anti-cancer drug chlorambucil. J. Biosci. Bioeng., 93, 618-621 (2002). Hirota K., Hanyu Y. 16233260
(RDB 1591) pAxCACD Cloned cytosine deaminase gene expression of Bifidobacterium longum and application to enzyme/pro-drug therapy of hypoxic solid tumors. Biosci. Biotechnol. Biochem., 66, 2362-2366 (2002). Nakamura T., Sasaki T., Fujimori M., Yazawa K., Kano Y., Amano J., Taniguchi S. 12506973
(RDB 1300) pBSKS-FosB
(RDB 1297) pJac-1
A homogeneous and noncompetitive immunoassay based on the enhanced fluorescence resonance energy transfer by leucine zipper interaction. Anal. Chem., 74, 5786-5792 (2002). Ohiro Y., Arai R., Ueda H., Nagamune T. 12463362
(RDB 1745) AxCALacZ Galpha(12/13) mediates alpha(1)-adrenergic receptor-induced cardiac hypertrophy. Circ. Res., 91, 961-969 (2002). Maruyama Y., Nishida M., Sugimoto Y., Tanabe S., Turner J.H., Kozasa T., Wada T., Nagao T., Kurose H. 12433842
(RDB 1745) AxCALacZ Regulated protein-protein interaction between aPKC and PAR-3 plays an essential role in the polarization of epithelial cells. Genes Cells, 7, 1161-1171 (2002). Nagai-Tamai Y., Mizuno K., Hirose T., Suzuki A., Ohno S. 12390250
(RDB 1679) pCALwL Developmental alteration of nerve injury induced glial cell line-derived neurotrophic factor (GDNF) receptor expression is crucial for the determination of injured motoneuron fate. J. Neurochem., 82, 961-975 (2002). Honma M., Namikawa K., Mansur K., Iwata T., Mori N., Iizuka H., Kiyama H. 12358802
(RDB 1745) AxCALacZ MAPK-upstream protein kinase (MUK) regulates the radial migration of immature neurons in telencephalon of mouse embryo. Development, 129, 4483-4495 (2002). Hirai S., Kawaguchi A., Hirasawa R., Baba M., Ohnishi T., Ohno S. 12223406
(RDB 1163) pSV2 proto-ret Differential expression of multiple isoforms of the ELKS mRNAs involved in a papillary thyroid carcinoma. Gene. Chromosome. Canc., 35, 30-37 (2002). Nakata T., Yokota T., Emi M., Minami S. 12203787
(RDB 1749) AxCANLacZ aPKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarization. J. Cell Sci., 115, 3565-3573 (2002). Suzuki A., Ishiyama C., Hashiba K., Shimizu M., Ebnet K., Ohno S. 12186943
(RDB 1694) pCIcc hp53 TNFalpha induces acetylation of p53 but attenuates its transcriptional activation in rheumatoid synoviocytes. Int. J. Mol. Med., 10, 269-275 (2002). Nakazawa M., Aratani S., Hatta M., Araya N., Daitoku H., Kawahara K., Watanabe S., Nakamura H., Yoshino S., Fujii R., Fujita H., Fukamizu A., Nishioka K., Nakajima T. 12165799
(RDB 1749) AxCANLacZ Over-expression of PAR-3 suppresses contact-mediated inhibition of cell migration in MDCK cells. Genes Cells., 7, 581-596 (2002). Mishima A., Suzuki A., Enaka M., Hirose T., Mizuno K., Ohnishi T., Mohri H., Ishigatsubo Y., Ohno S. 12059961
(RDB 1417) AxCAmIL12p40
(RDB 1745) AxCALacZ
(RDB 1414) AxCAmIL12p35
Interleukin-12-gene transduction makes DCs from tumor-bearing mice an effective inducer of tumor-specific immunity in a peritoneal dissemination model. Immunol. Lett., 83, 13-20 (2002). Furumoto K., Mori A., Yamasaki S., Inoue N., Yang W., Nakau M., Yasuda S., Arii S., Imamura M. 12057850
(RDB 1998) AxCAhp21 TGF-beta 1 as an enhancer of Fas-mediated apoptosis of lung epithelial cells. J. Immunol., 168, 6470-6478 (2002). Hagimoto N., Kuwano K., Inoshima I., Yoshimi M., Nakamura N., Fujita M., Maeyama T., Hara N. 12055267
(RDB 1749) AxCANLacZ Stability of a Recombinant Adenoviral Vector: Optimization of Conditions for Storage, Transport and Delivery Jpn. J. Cancer Res., 93, 598-603 (2002). Ugai H., Watanabe S., Suzuki E., Tsutsui-Nakata H., Yokoyama K., Murata T. 12036457
(RDB 1862) pCALNL5
(RDB 1748) AxCANCre
TGFbeta3-induced activation of RhoA/Rho-kinase pathway is necessary but not sufficient for epithelio-mesenchymal transdifferentiation: implications for palatogenesis. Int. J. Mol. Med., 9, 563-70 (2002). Kaartinen V., Haataja L., Nagy A., Heisterkamp N., Groffen J. 12011971
(RDB 2007) pAxCAhFADD Characterization of caspase-8L: a novel isoform of caspase-8 that behaves as an inhibitor of the caspase cascade. Blood, 99, 4070-4078 (2002). Himeji D., Horiuchi T., Tsukamoto H., Hayashi K., Watanabe T., Harada M. 12010809
(RDB 1372) Human MDR1 cDNA Transepithelial transport and cellular accumulation of steroid hormones and polychlorobiphenyl in porcine kidney cells expressed with human P-glycoprotein. Chemosphere., 46, 1505-1511 (2002). Fujise H., Annoura T., Sasawatari S., Ikeda T., Ueda K. 12002483
(RDB 1748) AxCANCre Cytoplasmic RNA vector derived from nontransmissible Sendai virus. Production and use. Methods Mol. Med., 69, 361-370 (2002). Iida A., Hasegawa M. 11987789
(RDB 1269) pHTH1 Stimulation of catecholamine biosynthesis via the protein kinase C pathway by endothelin-1 in PC12 rat pheochromocytoma cells. Biochem. Pharmacol., 63, 977-984 (2002). Takekoshi K., Ishii K., Shibuya S., Kawakami Y., Isobe K., Nakai T. 11911850
(RDB 1739) Ax1 CI hp40ip35 Interleukin (IL)-12 gene transduction and expression into human bronchial epithelial cells (BEAS-2B) by adenovirus vector. J. Med. Invest., 49, 74-82 (2002). Ogawa H., Nishimura N., Nishioka Y., Azuma M., Yanagawa H., Sone S. 11901765
(RDB 5953) pCM-TK Enhanced antitumor effect and reduced vector dissemination with fiber-modified adenovirus vectors expressing herpes simplex virus thymidine kinase. Cancer Gene Ther., 9, 236-242 (2002). Mizuguchi H., Hayakawa T. 11896439
(RDB 1687) pCM-hGM
(RDB 1524) pCAhMCSF
A novel murine model of Graves’ hyperthyroidism with intramuscular injection of adenovirus expressing the thyrotropin receptor. J. Immunol., 168, 2789-2794 (2002). Nagayama Y., Kita-Furuyama M., Ando T., Nakao K., Mizuguchi H., Hayakawa T., Eguchi K., Niwa M. 11884447
(RDB 1749) AxCANLacZ Analysis of gene expression profile induced by hepatocyte nuclear factor 4alpha in hepatoma cells using an oligonucleotide microarray. J. Biol. Chem., 277, 14011-14019(2002). Naiki T., Nagaki M., Shidoji Y., Kojima H., Imose M., Kato T., Ohishi N., Yagi K., Moriwaki H. 11834723
(RDB 1565) AxCAmKL
(RDB 1745) AxCALacZ
Adenovirus-mediated gene delivery and in vitro microinsemination produce offspring from infertile male mice. Proc. Natl. Acad. Sci. U. S. A., 99, 1383-1388 (2002). Kanatsu-Shinohara M., Ogura A., Ikegawa M., Inoue K., Ogonuki N., Tashiro K., Toyokuni S., Honjo T., Shinohara T. 11818536
(RDB 1184) Mouse E-cadherin full length cDNA Immobilized E-cadherin model can enhance cell attachment and differentiation of primary hepatocytes but not proliferation Biotechnol. Lett., 24, 1857-1862 (2002). Nagaoka M., Ise H., Akaike T.


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2001年

RDB No. Title Journal Author PMID
(RDB 1748) AxCANCre Controlled expansion of human endothelial cell populations by Cre-loxP-based reversible immortalization. Hum. Gene Ther., 13, 321-334 (2001). Noguchi H., Kobayashi N., Westerman K.A., Sakaguchi M., Okitsu T., Totsugawa T., Watanabe T., Matsumura T., Fujiwara T., Ueda T., Miyazaki M., Tanaka N., Leboulch P. 11812287
(RDB 1748) AxCANCre Removal of the floxed neo gene from a conditional knockout allele by the adenoviral Cre recombinase in vivo. Genesis., 31, 126-129 (2001). Kaartinen V., Nagy A. 11747203
(RDB 1750) AxCALNLNZ
(RDB 1749) AxCANLacZ
(RDB 1748) AxCANCre
Inflamed glomeruli-specific gene activation that uses recombinant adenovirus with the Cre/loxP system. J. Am. Soc. Nephrol., 12, 2330-2337 (2001). Yokoo T., Ohashi T., Utsunomiya Y., Shiba H., Shen J.S., Hisada Y., Eto Y., Kawamura T., Hosoya T. 11675409
(RDB 1269) pHTH1 Leptin stimulates catecholamine synthesis in a PKC-dependent manner in cultured porcine adrenal medullary chromaffin cells. Endocrinology, 142, 4861-4871 (2001). Takekoshi K., Ishii K., Nanmoku T., Shibuya S., Kawakami Y., Isobe K., Nakai T. 11606454
(RDB 1796) pZRmERK2 cDNA alpha-Synuclein affects the MAPK pathway and accelerates cell death. J. Biol. Chem., 276, 45320-45329 (2001). Iwata A., Maruyama M., Kanazawa I., Nukina N. 11560921
(RDB 1745) AxCALacZ Rapidly functional immobilization of immortalized human hepatocytes using cell adhesive GRGDS peptide-carrying cellulose microspheres. Cell Transplant., 10, 387-392 (2001). Kobayashi N., Taguchi T., Noguchi H., Okitsu T., Totsugawa T., Watanabe T., Matsumura T., Fujiwara T., Urata H., Kishimoto N., Hayashi N., Nakaji S., Murakami T., Tanaka N. 11549059
(RDB 1748) AxCANCre
(RDB 1745) AxCALacZ
Cre/loxP-based reversible immortalization of human hepatocytes. Cell Transplant., 10, 383-386 (2001). Kobayashi N., Noguchi H., Westerman K.A., Watanabe T., Matsumura T., Totsugawa T., Fujiwara T., Leboulch P., Tanaka N. 11549058
(RDB 1749) AxCANLacZ
(RDB 1678) pAxCAwt
PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex. Genes Cells, 6, 721-731 (2001). Yamanaka T., Horikoshi Y., Suzuki A., Sugiyama Y., Kitamura K., Maniwa R., Nagai Y., Yamashita A., Hirose T., Ishikawa H., Ohno S. 11532031
(RDB 1748 ) AxCANCre Accelerated degradation of cellular FLIP protein through the ubiquitin-proteasome pathway in p53-mediated apoptosis of human cancer cells. Oncogene, 20, 5225-5231 (2001). Fukazawa T., Fujiwara T., Uno F., Teraishi F., Kadowaki Y., Itoshima T., Takata Y., Kagawa S., Roth J.A., Tschopp J., Tanaka N. 11526513
(RDB 1482) pBluescript KS+mIFN gamma Induction of antitumor immunity by transduction of CD40 ligand gene and interferon-gamma gene into lung cancer. Cancer Gene Ther., 8, 421-429 (2001). Noguchi M., Imaizumi K., Kawabe T., Wakayama H., Horio Y., Sekido Y., Hara T., Hashimoto N., Takahashi M., Shimokata K., Hasegawa Y. 11498762
(RDB 1303) Human ETB receptor cDNA
(RDB 1415) pCAmIL12p40
Adoptive immunotherapy of experimental autoimmune encephalomyelitis via T cell delivery of the IL-12 p40 subunit. J. Immunol., 167, 2379-2387 (2001). Costa G.L., Sandora M.R., Nakajima A., Nguyen E.V., Taylor-Edwards C., Slavin A.J., Contag C.H., Fathman C.G., Benson J.M. 11490028
(RDB 1303) Human ETB receptor cDNA
(RDB 1302) Human ETA receptor cDNA
An unfolded putative transmembrane polypeptide, which can leado endoplasmic reticulum stress, is a substrate of Parkin. Cell, 105, 891-902 (2001). Imai Y., Soda M., Inoue H., Hattori N., Mizuno Y., Takahashi R. 11439185
(RDB 1678) pAxCAwt Overexpression of EC-SOD suppresses endothelial-cell-mediated LDL oxidation. Biochem. Biophys. Res. Commun., 285, 84-91 (2001). Takatsu H., Tasaki H., Kim H.N., Ueda S., Tsutsui M., Yamashita K., Toyokawa T., Morimoto Y., Nakashima Y., Adachi T. 11437376
(RDB 1745) AxCALacZ Expression of the oxygen-regulated protein ORP150 accelerates wound healing by modulating intracellular VEGF transport. J. Clin. Invest., 108, 41-50 (2001). Ozawa K., Kondo T., Hori O., Kitao Y., Stern D.M., Eisenmenger W., Ogawa S., Ohshima T. 11435456
(RDB 1748) AxCANCre Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis. EMBO J., 20, 3333-3341 (2001). Ohba Y., Ikuta K., Ogura A., Matsuda J., Mochizuki N., Nagashima K., Kurokawa K., Mayer B.J., Maki K., Miyazaki J., Matsuda M. 11432821
(RDB 2276) pAxCAhMSSP (reverse)
(RDB 1440) pMFGmIL1RA
Genetically modified bone marrow continuously supplies anti-inflammatory cells and suppresses renal injury in mouse Goodpasture syndrome. Blood, 98, 57-64 (2001). Yokoo T., Ohashi T., Utsunomiya Y., Shen J.S., Hisada Y., Eto Y., Kawamura T., Hosoya T. 11418463
(RDB 1208) pRHO1 Brain responses to acute withdrawal in phenobarbital-dependent rats. Eur. J. Pharmacol., 421, 101-108 (2001). Tanaka S., Okuno Y., Numazawa S., Yamamoto T., Shioda S., Yoshida T. 11399265
(RDB 1469) pBluescript SKII+mGM-CSF
(RDB 1474) pBluescript KS+mIL6
Antitumor Effect on Murine Renal Cell Carcinoma by Autologous Tumor Vaccines Genetically Modified with Granulocyte-Macrophage Colony-Stimulating Factor and Interleukin-6 Cells. J. Immunother (1991)., 24, 205-211 (2001). Kinoshita Y., Kono T., Yasumoto R., Kishimoto T., Wang C.Y., Haas G.P., Nishisaka N. 11395635
(RDB 1801) RBP-J A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promoters. Mol. Cell Biol., 21, 4337-4346 (2001). Kitagawa M., Oyama T., Kawashima T., Yedvobnick B., Kumar A., Matsuno K., Harigaya K. 11390662
(RDB 1447) pMFGmIL12p40 Antigen-specific T cell-mediated gene therapy in collagen-induced arthritis. J. Clin. Invest., 107, 1293-301 (2001). Nakajima A., Seroogy C.M., Sandora M.R., Tarner I.H., Costa G.L., Taylor-Edwards C., Bachmann M.H., Contag C.H., Fathman C.G. 11375419
(RDB 1746) Ax1w1 Suppression of arthritis by forced expression of cyclin-dependent kinase inhibitor p21(Cip1) gene into the joints. Int. Immunol., 13, 723-731 (2001). Nonomura Y., Koike R., Nishio J., Tsubata R., Kohsaka H., Kubota T., Miyasaka N. 11369699
(RDB 1344) pUC kit EH1 Ulcerative proctitis, rectal prolapse, and intestinal pseudo-obstruction in transgenic mice overexpressing hepatocyte growth factor/scatter factor. Lab. Invest., 81, 297-305 (2001). Takayama H., Takagi H., Larochelle W.J., Kapur R.P., Merlino G. 11310823
anonymous Identification of differentially expressed genes in hepatocellular carcinoma with cDNA microarrays. Hepatology, 33, 832-840 (2001). Shirota Y., Kaneko S., Honda M., Kawai H.F., Kobayashi K. 11283847
(RDB 1796) pZRmERK2 cDNA alpha-Synuclein forms a complex with transcription factor Elk-1. J. Neurochem., 77, 239-252 (2001). Iwata A., Miura S., Kanazawa I., Sawada M., Nukina N. 11279280
(RDB 1749) AxCANLacZ Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures. J. Cell Biol., 152, 1183-1196 (2001). Suzuki A., Yamanaka T., Hirose T., Manabe N., Mizuno K., Shimizu M., Akimoto K., Izumi Y., Ohnishi T., Ohno S. 11257119
(RDB 1276) pco12 EGFR Insulin-like growth factor I (IGF-I) protects cells from apoptosis by Alzheimer’s V642I mutant amyloid precursor protein through IGF-I receptor in an IGF-binding protein-sensitive manner. J. Neurosci., 21, 1902-1910 (2001). Niikura T., Hashimoto Y., Okamoto T., Abe Y., Yasukawa T., Kawasumi M., Hiraki T., Kita Y., Terashita K., Kouyama K., Nishimoto I. 11245675
(RDB 1739) Ax1 CI hp40ip35 Enhanced efficiency by centrifugal manipulation of adenovirus-mediated interleukin 12 gene transduction into human monocyte-derived dendritic cells. Hum. Gene Ther., 12, 333-346 (2001). Nishimura N., Nishioka Y., Shinohara T., Sone S. 11242526
anonymous Differential gene expression between chronic hepatitis B and C hepatic lesion. Gastroenterology., 120, 955-966 (2001). Honda, M., Kaneko, S., Kawai, H., Shirota, Y., Kobayashi, K. 11231949
anonymous alpha-fetoprotein-producing hepatoma cell lines share common expression profiles of genes in various categories demonstrated by cDNA microarray analysis. Hepatology, 33, 676-691 (2001). Kawai H.F., Kaneko S., Honda M., Shirota Y., Kobayashi K. 11230749
(RDB 1750) AxCALNLNZ
(RDB 1679) pCALwL
Targeting the replication of adenovirus to p53-defective thyroid carcinoma with a p53-regulated Cre/loxP system. Cancer Gene Ther., 8, 36-44 (2001). Nagayama Y., Nishihara E., Namba H., Yokoi H., Hasegawa M., Mizuguchi H., Hayakawa T., Hamada H., Yamashita S., Niwa M. 11219492
(RDB 1269) pHTH1 Ca(2+) mobilization, tyrosine hydroxylase activity, and signaling mechanisms in cultured porcine adrenal medullary chromaffin cells: effects of leptin. Endocrinology, 142, 290-298 (2001). Takekoshi K., Ishii K., Kawakami Y., Isobe K., Nanmoku T., Nakai T. 11145592
(RDB 1560) AxCAmIL1RA Genetically modified bone marrow-derived vehicle cells site specifically deliver ananti-inflammatory cytokine to inflamed interstitium of obstructive nephropathy. J. Immunol., 166, 609-616 (2001). Yamagishi H., Yokoo T., Imasawa T., Mitarai T., Kawamura T., Utsunomiya Y. 11123344


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2000年

RDB No. Title Journal Author PMID
(RDB 1441) pMFGmIL2 A speedy method to detect inserted DNA fragment in cell lines transpected with retroviral vectors. Cytotechnology, 34, 243-252 (2000). Ding, L-H, Iimura E., Saijo K., Hamada H., Ohno T. 19003400
(RDB 1746) Ax1w1
(RDB 1749) AxCANLacZ
Transfection of the plasma-type platelet-activating factor acetylhydrolase gene attenuates glutamate-induced apoptosis in cultured rat cortical neurons. Brain Res., 885, 128-132 (2000). Hirashima Y., Ueno H., Karasawa K., Yokoyama K., Setaka M., Takaku A. 11121539
(RDB 1745) AxCALacZ G alpha(i) and G alpha(o) are target proteins of reactive oxygen species. Nature, 408, 492-495 (2000). Nishida M., Maruyama Y., Tanaka R., Kontani K., Nagao T., Kurose H. 11100733
(RDB 1446) pMFGmIL10 Antigen-specific T cells transduced with IL-10 ameliorate experimentally induced arthritis without impairing the systemic immune response to the antigen. J. Immunol., 165, 5980-5986 (2000). Setoguchi K., Misaki Y., Araki Y., Fujio K., Kawahata K., Kitamura T., Yamamoto K. 11067961
(RDB 1385) Inducible NOS cDNA Geranylgeranylacetone stimulates mucin synthesis in cultured guinea pig gastric pit cells by inducing a neuronal nitric oxide synthase. J. Gastroenterol., 35, 673-681 (2000). Rokutan K., Teshima S., Kawai T., Kawahara T., Kusumoro K., Mizushima T., Kishi K. 11023038
(RDB 1410) AxCAmIL10 Interleukin-10 gene transfer improves the survival rate of mice inoculated with Escherichia coli. Crit. Care. Med., 28, 2685-2689 (2000). Takakuwa T., Endo S., Shirakura Y., Yokoyama M., Tamatani M., Tohyama M., Aozasa K., Inada K. 10966236
(RDB 1417) AxCAmIL12p40
(RDB 1414) AxCAmIL12p35
Spleen-derived dendritic cells engineered to enhance interleukin-12 production elicit therapeutic antitumor immune responses. Int. J. Cancer., 87, 665-672 (2000). Furumoto K., Arii S., Yamasaki S., Mizumoto M., Mori A., Inoue N., Isobe N., Imamura M. 10925360
(RDB 1269) pHTH1 kappa-Opioid inhibits catecholamine biosynthesis in PC12 rat pheochromocytoma cell. FEBS Lett., 477, 273-277 (2000). Takekoshi K., Ishii K., Kawakami Y., Isobe K., Nakai T. 10908734
(RDB 1694) pCIcc hp53 Regulation of Lef-mediated Transcription and p53-dependent Pathway by Associating β-Catenin with CBP/p300 J. Biol. Chem., 275, 35170-35175 (2000). Miyagishi M., Fujii R., Hatta M., Yoshida E., Araya N., Nagafuchi A., Ishihara S., Nakajima T., Fukamizu A. 10906119
(RDB 1269) pHTH1 Effects of natriuretic peptides (ANP, BNP, CNP) on catecholamine synthesis and TH mRNA levels in PC12 cells. Life Sci., 66, PL303-311 (2000). Takekoshi K., Ishii K., Isobe K., Nomura F., Nammoku T., Nakai T. 10834306
(RDB 1745) AxCALacZ Enhancement of adenovirus-mediated gene transfer into dermal fibroblasts in vitro and in vivo by polyethylene glycol 6000. J. Dermatol., 27, 244-251 (2000). Ohsawa T., Nakamura T., Mihara M., Sato K. 10824488
(RDB 1675) pxCANCre Glioma/glioblastoma-specific adenoviral gene expression using the nestin gene regulator. Gene Ther., 7, 686-693 (2000). Kurihara H., Zama A., Tamura M., Takeda J., Sasaki T., Takeuchi T. 10800092
(RDB 1245) P450 2B1 (CYP2B1) cDNA Differential suppression of liver-specific genes in regenerating rat liver induced by extended hepatectomy. J. Hepatol., 32, 636-644 (2000). Kurumiya Y., Nozawa K., Sakaguchi K., Nagino M., Nimura Y., Yoshida S. 10782913
(RDB 1579) AxCEAprZ The dominant negative H-ras mutant, N116Y, suppresses growth of metastatic human pancreatic cancer cells in the liver of nude mice. Gene Ther., 7, 518-526 (2000). Takeuchi M., Shichinohe T., Senmaru N., Miyamoto M., Fujita H., Takimoto M., Kondo S., Katoh H., Kuzumaki N. 10757026
anonymous Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development, 127, 1737-1749 (2000). Ko M.S., Kitchen J.R., Wang X., Threat T.A., Wang X., Hasegawa A., Sun T., Grahovac M.J., Kargul GJ, Lim MK, Cui Y, Sano Y, Tanaka T, Liang Y, Mason S., Paonessa P.D., Sauls A.D., DePalma G.E., Sharara R., Rowe L.B., Eppig J., Morrell C., Doi H. 10725249
(RDB 1127) pHSP90 Suppression of heat shock protein-70 by ceramide in heat shock-induced HL-60 cell apoptosis. J. Biol. Chem., 275, 8872-8879 (2000). Kondo T., Matsuda T., Tashima M., Umehara H., Domae N., Yokoyama K., Uchiyama T., Okazaki T. 10722733
(RDB 1127) pHSP90 Role of c-jun expression increased by heat shock- and ceramide-activated caspase-3 in HL-60 cell apoptosis. Possible involvement of ceramide in heat shock-induced apoptosis. J. Biol. Chem., 275, 7668-7676 (2000). Kondo T., Matsuda T., Kitano T., Takahashi A., Tashima M., Ishikura H., Umehara H., Domae N., Uchiyama T., Okazaki T. 10713077
(RDB 1510) pCAmTNF alpha The timing of GM-CSF expression plasmid administration influences the Th1/Th2 response induced by an HIV-1-specific DNA vaccine. J. Immunol., 164, 3102-3111 (2000). Kusakabe K., Xin K.Q., Katoh H., Sumino K., Hagiwara E., Kawamoto S., Okuda K., Miyagi Y., Aoki I., Nishioka K., Klinman D., Okuda K. 10706700
(RDB 1748) AxCANCre
(RDB 1745) AxCALacZ
Prevention of acute liver failure in rats with reversibly immortalized human hepatocytes. Science, 287, 1258-1262 (2000). Kobayashi N., Fujiwara T., Westerman K.A., Inoue Y., Sakaguchi M., Noguchi H., Miyazaki M., Cai J., Tanaka N., Fox I.J., Leboulch P. 10678831
(RDB 1748) AxCANCre
(RDB 74) 659-668 (2000).,Araki T.
(RDB 1750) AxCALNLNZ
Shp-2 specifically regulates several tyrosine-phosphorylated proteins in brain-derived neurotrophic factor signaling in cultured cerebral cortical neurons. Neurochem., 74, 659-668 (2000). Araki T., Yamada M., Ohnishi H., Sano S., Uetsuki T., Hatanaka H. 10646517
(RDB 1303) Human ETB receptor cDNA
(RDB 1302) Human ETA receptor cDNA
Endogenously Generated Nitric Oxide by Nitric-Oxide Synthase Gene Transfer Inhibits Cellular Proliferation. J. Pharmacol. Exp. Ther., 292, 387-393 (2000). Maeda Y., Ikeda U., Oya K., Shimpo M., Ueno S., Okada K., Saito T., Mano H., Ozawa K., Shimada K. 10604975
(RDB 1195) Rat TGF beta 1 cDNA Dietary docosahexaenoic acid ameliorates, but rapeseed oil and safflower oil accelerate renal injury in stroke-prone spontaneously hypertensive rats as compared with soybean oil, which is associated with expression for renal transforming growth factor-beta, fibronectin and renin. Biochim. Biophys. Acta -Mol. Cell Biol. Lip., 1483, 101-110 (2000). Miyazaki M., Takemura N., Watanabe S., Hata N., Misawa Y., Okuyama H. 10601699


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1999年以前

RDB No. Title Journal Author PMID
(RDB 1482) pBluescript KS+mIFN gamma
(RDB 1473) pBluescript KS+mIL4
(RDB 1469) pBluescript SKII+mGM-CSF
DNA immunization with Plasmodium falciparum serine repeat antigen: regulation of humoral immune response by coinoculation of cytokine expression plasmid. Parasitol. Int., 48, 27-33 (1999). Sakai T., Horii T., Hisaeda H., Zhang M., Ishii K., Nakano Y., Maekawa Y., Izumi K., Nitta Y., Miyazaki J., Himeno K. 11269323
(RDB 1560) AxCAmIL1RA Prophylaxis of antibody-induced acute glomerulonephritis with genetically modified bone marrow-derived vehicle cells. Hum. Gene Ther., 10, 2673-2678 (1999). Yokoo T., Ohashi T., Utsunomiya Y., Kojima H., Imasawa T., Kogure T., Hisada Y., Okabe M., Eto Y., Kawamura T., Hosoya T. 10566895
(RDB 1130) pBS rcjun-1 Asbestos-induced phosphorylation of epidermal growth factor receptor is linked to c-fos and apoptosis. Am. J. Physiol., 277, 684-693 (1999). Zanella C.L., Timblin C.R., Cummins A., Jung M., Goldberg J., Raabe R., Tritton T.R., Mossman B.T. 10516208
(RDB 1796) pZRmERK2 cDNA CrkL mediates Ras-dependent activation of the Raf/ERK pathway through the guanine nucleotide exchange factor C3G in hematopoietic cells stimulated with erythropoietin or interleukin-3. J. Biol. Chem., 274, 30154-30162 (1999). Nosaka Y., Arai A., Miyasaka N., Miura O. 10514505
(RDB 1745) AxCALacZ Hepatoprotective action of adenovirus-transferred HNF-3gamma gene in acute liver injury caused by CCl4. FEBS Let., 459, 1-4 (1999). Nakamura T., Akiyoshi H., Shiota G., Isono M., Nakamura K., Moriyama M., Sato K. 10508906
(RDB 1198) ETR103 Angiotensin II stimulates platelet-derived growth factor-B chain expression in newborn rat vascular smooth muscle cells and neointimal cells through Ras, extracellular signal-regulated protein kinase, and c-Jun N-terminal protein kinase mechanisms. Circ. Res., 85, 565-574 (1999). Deguchi J., Makuuchi M., Nakaoka T., Collins T., Takuwa Y. 10506481
(RDB 4215) CEPH MEGA YAC Clone(745-F-8)
(RDB 4215) CEPH MEGA YAC Clone(880-G-9)
(RDB 4215) CEPH MEGA YAC Clone(638-E-12)
(RDB 4215) CEPH MEGA YAC Clone(964-C-10)
Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13). Gene. Chromosome. Canc., 26, 192-202 (1999). Yagasaki F., Jinnai I., Yoshida S., Yokoyama Y., Matsuda A., Kusumoto S., Kobayashi H., Terasaki H., Ohyashiki K., Asou N., Murohashi I., Bessho M., Hirashima K. 10502316
(RDB 1441) pMFGmIL2
(RDB 1454) pMFGmIFN gamma
(RDB 1469) pBluescript SKII+mGM-CSF
Immunotherapy for lung metastases of murine renal cell carcinoma: synergy between radiation and cytokine-producing tumor vaccines. J. Immunother., 22, 308-314 (1999). Nishisaka N., Maini A., Kinoshita Y., Yasumoto R., Kishimoto T., Jones R.F., Morse P., Hillman G.G., Wang C.Y., Haas G.P. 10404432
(RDB 1745) AxCALacZ Adenovirus-mediated transfer of wild-type p53 gene results in apoptosis or growth arrest in human cultured gastric carcinoma cells. Int. J. Oncol., 15, 229-235 (1999). Tatebe S., Matsuura T., Endo K., Teramachi K., Nakamura T., Sato K., Ito H. 10402231
(RDB 1595) pHSG-C3G CrkL activates integrin-mediated hematopoietic cell adhesion through the guanine nucleotide exchange factor C3G. Blood., 93, 3713-3722 (1999). Arai A., Nosaka Y., Kohsaka H., Miyasaka N., Miura O. 10339478
(RDB 1211) pGEMhIL-6 GT IL-6 synthesis by rheumatoid synoviocytes is autonomously upregulated at the transcriptional level. J. Allergy Clin. Immunol., 103, S437-444 (1999). Miyazawa K., Mori A., Okudaira H. 10329846
(RDB 1194) Rat HGF cDNA Wy-14,643, a peroxisome proliferator, inhibits compensative cell proliferation and hepatocyte growth factor mRNA expression in the rat liver. Cancer Lett., 135, 145-150 (1999). Motoki Y., Tamura H., Watanabe T., Suga T. 10096422
(RDB 1745) AxCALacZ Adenovirus-mediated gene expression in the septal cells of cirrhotic rat livers. J. Hepatol., 30, 101-106 (1999). Nakamura T., Akiyoshi H., Saito I., Sato K. 9927156
(RDB 1245) P450 2B1 (CYP2B1) cDNA Biochemical functions and mRNA expression of rat hepatocytes in a bioartifical liver module. Yonago Acta medica, 42, 103-112 (1999). Okada S., Kono Y., Shiraki K.
(RDB 1130) pBS rcjun-1 Heat shock protein expression in hearts hypertrophied by genetic and nongenetic hypertension. Heart Vessels., 13, 30-39 (1998). Iwabuchi K., Tajima M., Isoyama S. 9923563
(RDB 1745) AxCALacZ A newly developed adenovirus-mediated transfer of a wild-type p53 gene increases sensitivity to cis-diamminedichloroplatinum (II) in p53-deleted ovarian cancer cells. Eur. J. Cancer., 34, 1802-1806 (1998). Kanamori Y., Kigawa J., Minagawa Y., Irie T., Oishi T., Shimada M., Takahashi M., Nakamura T., Sato K., Terakawa N. 9893672
(RDB 1745) AxCALacZ Adenovirus-transferred HNF-3 gamma conserves some liver functions in primary cultured hepatocytes of adult rats. Biochem. Biophys. Res. Commun., 253, 352-357 (1998). Nakamura T., Mura T., Saito K., Ohsawa T., Akiyoshi H., Sato K. 9878541
(RDB 1130) pBS rcjun-1 Glutathione depletion inhibits oxidant-induced activation of nuclear factor-kappa B, AP-1, and c-Jun/ATF-2 in cultured guinea-pig gastric epithelial cells. J. Gastroenterol., 33, 646-655 (1998). Rokutan K., Teshima S., Miyoshi M., Kawai T., Nikawa T., Kishi K. 9773928
(RDB 1269) pHTH1
(RDB 1270) pPCDC13 EcoA
(RDB 1271) pDBH-1
A novel protein containing Cdc10/SWI6 motifs regulates expression of mRNA encoding catecholamine biosynthesizing enzymes. J. Biol. Chem., 273, 27051-27054 (1998). Yamakuni T., Yamamoto T., Hoshino M., Song S.Y., Yamamoto H., Kunikata-Sumitomo M., Minegishi A., Kubota M., Ito M., Konishi S. 9765218
(RDB 1207) pHHO1 Oxygen tension regulates heme oxygenase-1 gene expression in mammalian cell lines. Cell Biochem. Funct., 16, 183-193 (1998). Takahashi S., Takahashi Y., Yoshimi T., Miura T. 9747510
(RDB 1211) pGEMhIL-6 GT Regulation of interleukin-1beta-induced interleukin-6 gene expression in human fibroblast-like synoviocytes by p38 mitogen-activated protein kinase. J. Biol. Chem., 273, 24832-24838 (1998). Miyazawa K., Mori A., Miyata H., Akahane M., Ajisawa Y., Okudaira H. 9733787
(RDB 1276) pco12 EGFR Enhanced expression of heparin-binding EGF-like growth factor and its receptor in hypertrophied left ventricle of spontaneously hypertensive rats. Cardiovasc. Res., 38, 365-374 (1998). Fujino T., Hasebe N., Fujita M., Takeuchi K., Kawabe J., Tobise K., Higashiyama S., Taniguchi N., Kikuchi K. 9709397
(RDB 1208) pRHO1 Altered activities of transcription factors and their related gene expression in cardiac tissues of diabetic rats. Diabetes., 47, 1318-1325 (1998). Nishio Y., Kashiwagi A., Taki H., Shinozaki K., Maeno Y., Kojima H., Maegawa H., Haneda M., Hidaka H., Yasuda H., Horiike K., Kikkawa R. 9703334
(RDB 1298) 465.20 Leptin receptor signal transduction: OBRa and OBRb of fa type. Biochem. Biophys. Res. Commun., 246, 752-759 (1998). Yamashita T., Murakami T., Otani S., Kuwajima M., Shima K. 9618284
(RDB 1269) pHTH1 Expression of mRNA coding for four catecholamine-synthesizing enzymes in human adrenal pheochromocytomas. Eur. J. Endocrinol., 138, 383-387 (1998). Isobe K., Nakai T., Yukimasa N., Nanmoku T., Takekoshi K., Nomura F. 9578504
(RDB 1211) pGEMhIL-6 GT Transcriptional roles of CCAAT/enhancer binding protein-beta, nuclear factor-kappaB, and C-promoter binding factor 1 in interleukin (IL)-1beta-induced IL-6 synthesis by human rheumatoid fibroblast-like synoviocytes. J. Biol. Chem., 273, 7620-7627 (1998). Miyazawa K., Mori A., Yamamoto K., Okudaira H. 9516466
(RDB 1211) pGEMhIL-6 GT Constitutive transcription of the human interleukin-6 gene by rheumatoid synoviocytes: spontaneous activation of NF-kappaB and CBF1. Am. J. Pathol., 152, 793-803 (1998). Miyazawa K., Mori A., Yamamoto K., Okudaira H. 9502421
(RDB 1130) pBS rcjun-1
(RDB 1362) c-jun -730, -79 CAT
Stretch activates jun N-terminal Kinase/Stress-activated protein kinase in vascular smooth muscle cells through mechanisms involving autocrine ATP stimulation of purinoceptors. J. Biol. Chem., 273, 6334-6340 (1998). Hamada K., Takuwa N., Yokoyama K., Takuwa Y. 9497362
(RDB 1437) pGKlacZ Development of a novel selective amplifier gene for controllable expansion of transduced hematopoietic cells. Blood, 90, 3884-3892 (1997). Ito K., Ueda Y., Kokubun M., Urabe M., Inaba T., Mano H., Hamada H., Kitamura T., Mizoguchi H., Sakata T., Hasegawa M., Ozawa K. 9354655
(RDB 1195) Rat TGF beta 1 cDNA TSC-36 (follistatin-related polypeptide) gene expression in estrogen receptor positive osteoblastic cell line, CDO7F. Calcified. Tissue Int., 61, 400-403 (1997). Ohashi T., Sato S., Yoshiki A., Kusakabe M. 9351882
(RDB 1385) Inducible NOS cDNA Oxidant-induced activation of nuclear factor-kappa B in cultured guinea pig gastric epithelial cells. Dig. Dis. Sci., 42, 1880-1889 (1997). Rokutan K., Teshima S., Miyoshi M., Nikawa T., Kishi K. 9331151
(RDB 1194) Rat HGF cDNA Decreased hepatocyte growth factor level by Wy-14,643, non-genotoxic hepatocarcinogen in F-344 rats. Carcinogenesis, 18, 1303-1309 (1997). Motoki Y., Tamura H., Morita R., Watanabe T., Suga T. 9230272
(RDB 1208) pRHO1 Increases in the mRNA levels of gamma-glutamyltransferase and heme oxygenase-1 in the rat lung after ozone exposure. Biochem. Pharmacol., 53, 1061-1064 (1997). Takahashi Y., Takahashi S., Yoshimi T., Miura T., Mochitate K., Kobayashi T. 9174121
(RDB 1298) 465.20 Leptin receptor of Zucker fatty rat performs reduced signal transduction. Diabetes, 46, 1077-1080 (1997). Yamashita T., Murakami T., Iida M., Kuwajima M., Shima K. 9166683
(RDB ) human HSP90-alpha Messenger Ribonucleic Acid Expression of Heat Shock Proteins HSP70 and HSP90 in Human Endometrium and Myometrium during the Menstrual Cycle. J. Clin. Endocrinol. Metabol., 82, 1385-1389 (1997). Komatsu T., Konishi I., Fukumoto M., Nanbu K., Koshiyama M., Mandai M., Mori T. 9141521
(RDB 1298) 465.20 A short form of leptin receptor performs signal transduction. Biochem. Biophys. Res. Commun., 231, 26-29 (1997). Murakami T., Yamashita T., Iida M., Kuwajima M., Shima K. 9070213
(RDB ) pcDNA I Neo Lysophosphatidylcholine transduces Ca2+ signaling via the platelet-activating factor receptor in macrophages. Am. J. Physiol., 272, H17-H24 (1997). Ogita T., Tanaka Y., Nakaoka T., Matsuoka R., Kira Y., Nakamura M., Shimizu T., Fujita T. 9038918
(RDB 1271) pDBH-1
(RDB 1269) pHTH1
Pituitary adenylate cyclase-activating polypeptide induces gene expression of the catecholamine synthesizing enzymes, tyrosine hydroxylase and dopamine beta hydroxylase, through 3′,5′-cyclic adenosine monophosphate- and protein kinase C-dependent mechanisms in cultured porcine adrenal medullary chromaffin cells. Neuropeptides., 30, 167-175 (1996). Isobe K., Yukimasa N., Nakai T., Takuwa Y. 8771559
(RDB 1276) pco12 EGFR An epidermal growth factor receptor/Jak2 tyrosine kinase domain chimera induces tyrosine phosphorylation of Stat5 and transduces a growth signal in hematopoietic cells. J. Biol. Chem., 271, 19483-19488 (1996). Nakamura N., Chin H., Miyasaka N., Miura O. 8702638
(RDB 1244) P450 1A2 (CYP1A2) cDNA
(RDB 1245) P450 2B1 (CYP2B1) cDNA
A cardiotonic steroid bufalin-induced differentiation of THP-1 cells. Involvement of Na+, K(+)-ATPase inhibition in the early changes in proto-oncogene expression. Biochem. Pharmacol., 52, 321-329 (1996). Numazawa S., Inoue N., Nakura H., Sugiyama T., Fujino E., Shinoki M., Yoshida T., Kuroiwa Y. 8694857
(RDB 1245) P450 2B1 (CYP2B1) cDNA
(RDB 1244) P450 1A2 (CYP1A2) cDNA
Suppressed expression of phenobarbital-inducible hepatic cytochrome P-450s in Eisai-hyperbilirubinuria rats (EHBR/Eis). J. Pharmacol. Exp. Ther., 277, 1676-1684 (1996). Oguro T., Kaneko E., Kaneko Y., Numazawa S., Imaoka S., Funae Y., Mikami T., Yoshida T. 8667238
(RDB 1246) HLA-G.7.0 E HLA-G gene polymorphism in a Japanese population. Immunogenetics., 44, 186-191 (1996). Yamashita T., Fujii T., Watanabe Y., Tokunaga K., Tadokoro K., Juji T., Taketani Y. 8662085
(RDB 1130) pBS rcjun-1
(RDB 1362) c-jun -730, -79 CAT
Detection of living cells that express AP1 using a fluorolabeled DNA probe. FEBS Lett., 388, 16-20 (1996). Shimokawa, N., Miura, M. 8654580
(RDB 1271) pDBH-1
(RDB 1270) pPCDC13 EcoA
(RDB 1269) pHTH1
Expression of mRNAs coding for catecholamine synthesizing enzymes in human adrenal pheochromocytoma. Jpn. J. Clin. Pathol., 43, 540-544 (1995). Isobe K., Yukimasa N., Takekoshi K., Nomura F., Nakai T. 7602797
(RDB 1130) pBS rcjun-1 Requirement of AP-1 for ceramide-induced apoptosis in human leukemia HL-60 cells. J. Biol. Chem., 270, 27326-27331 (1995). Sawai H., Okazaki T., Yamamoto H., Okano H., Takeda Y., Tashima M., Sawada H., Okuma M., Ishikura H., Umehara H., et al. 7592995
(RDB 917) pAxcw Construction and characterization of adenoviral vector expressing biologically active brain-derived neurotrophic factor. Biochem. Biophys. Res. Commun., 212, 712-717 (1995). Kojima H., Inuzuka S., Miwa T., Furukawa S., Hayashi K., Kanegae Y., Saito I., Ohishi N., Takamori M., Yagi K. 7542888
(RDB 1029) pBLUR8 Chimeric YACs were generated at unreduced rates in conditions that suppress coligation. Nucleic. Acids. Res., 22, 1651-1654 (1994). Wada M., Abe K., Okumura K., Taguchi H., Kohno K., Imamoto F., Schlessinger D., Kuwano M. 8202367

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